Ida Skrinde Leren
- MD, PhD
Ida Skrinde Leren, MD, PhD, Associate researcher
Leren successfully defended her thesis "Ventricular arrhythmias in cardiac ion channel diseases; occurrence, treatment and risk stratification" in June 2016. Her supervisors were Associate Professor Kristina Hermann Haugaa, MD, PhD and Professor Thor Edvardsen, MD, PhD.
Dr. Leren was awarded with His Majesty the King’s Gold Medal for Best Doctoral Thesis within Medicin anno 2016.
The findings in the thesis gained wide international attention and helped change clinical practice and guidelines for the treatment of CPVT (catecholaminergic polymorphic ventricular tachycardia). The recommendations now state that asymptomatic family members receive pre-treatment with beta-blockers as preventative care. The follow-up study examined differences in the treatment effect of different beta-blockers at CPVT and indicated that the beta-blocker nadolol was better in protecting against severe rhythm disturbances than the traditional beta- blockers.
This finding has been important for the selection of drugs for these young patients and is the largest study of its kind. The third article illustrated the connection between the electrical and mechanical function of the heart utilizing sensitive image surveys developed at Oslo University Hospital.