Øystein Fodstad

  • Professor emeritus
  • +47 22 78 23 11

Immunotoxins, preclinical and planning of new clinical studies. Involved in attempts to obtain funding and to secure IPR.

B7-H3: together with Caroline writing manuscripts on the mechanisms of action and clinical significance of B7-H3, in addition review articles. Collaboration with the US company Macrogenics.
Collaborating with Dr. Hector Peinado in Madrid on the role of exosomes in brain metastases.


Publications 2022

Nunes-Xavier CE, Emaldi M, Guldvik IJ, Ramberg H, Taskén KA, Mælandsmo GM, Fodstad Ø, Llarena R, Pulido R, López JI (2022)
Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
Pathol Res Pract, 241, 154243
DOI 10.1016/j.prp.2022.154243, PubMed 36481650

Nunes-Xavier CE, Mingo J, Emaldi M, Flem-Karlsen K, Mælandsmo GM, Fodstad Ø, Llarena R, López JI, Pulido R (2022)
Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer
Front Oncol, 12, 873516
DOI 10.3389/fonc.2022.873516, PubMed 35692804

Publications 2021

Nunes-Xavier CE, Kildal W, Kleppe A, Danielsen HE, Waehre H, Llarena R, Maelandsmo GM, Fodstad Ø, Pulido R, López JI (2021)
Immune checkpoint B7-H3 protein expression is associated with poor outcome and androgen receptor status in prostate cancer
Prostate, 81 (12), 838-848
DOI 10.1002/pros.24180, PubMed 34125445

Svendsen HA, Meling TR, Nygaard V, Waagene S, Russnes H, Juell S, Rogne SG, Pahnke J, Helseth E, Fodstad Ø, Maelandsmo GM (2021)
Novel human melanoma brain metastasis models in athymic nude fox1nu mice: Site-specific metastasis patterns reflecting their clinical origin
Cancer Med, 10 (23), 8604-8613
DOI 10.1002/cam4.4334, PubMed 34612023

Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
Ann Surg Oncol, 28 (9), 5252-5262
DOI 10.1245/s10434-021-10022-0, PubMed 34019185

Publications 2020

Flem-Karlsen K, Fodstad Ø, Nunes-Xavier CE (2020)
B7-H3 Immune Checkpoint Protein in Human Cancer
Curr Med Chem, 27 (24), 4062-4086
DOI 10.2174/0929867326666190517115515, PubMed 31099317

Saeednejad Zanjani L, Madjd Z, Axcrona U, Abolhasani M, Rasti A, Asgari M, Fodstad Ø, Andersson Y (2020)
Cytoplasmic expression of B7-H3 and membranous EpCAM expression are associated with higher grade and survival outcomes in patients with clear cell renal cell carcinoma
Ann Diagn Pathol, 46, 151483
DOI 10.1016/j.anndiagpath.2020.151483, PubMed 32143173

Publications 2019

Andersson Y, Inderberg EM, Kvalheim G, Herud TM, Engebraaten O, Flatmark K, Dueland S, Fodstad Ø (2019)
Immune stimulatory effect of anti-EpCAM immunotoxin - improved overall survival of metastatic colorectal cancer patients
Acta Oncol, 59 (4), 404-409
DOI 10.1080/0284186X.2019.1704864, PubMed 31876430

Flem-Karlsen K, Tekle C, Øyjord T, Flørenes VA, Mælandsmo GM, Fodstad Ø, Nunes-Xavier CE (2019)
p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
Sci Rep, 9 (1), 5839
DOI 10.1038/s41598-019-42303-w, PubMed 30967582

Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2019)
ImmunoPeCa trial: Long-term outcome following intraperitoneal MOC31PE immunotoxin treatment in colorectal peritoneal metastasis
Eur J Surg Oncol, 47 (1), 134-138
DOI 10.1016/j.ejso.2019.04.014, PubMed 31036394

Saeednejad Zanjani L, Madjd Z, Rasti A, Asgari M, Abolhasani M, Tam KJ, Roudi R, Mælandsmo GM, Fodstad Ø, Andersson Y (2019)
Spheroid-Derived Cells From Renal Adenocarcinoma Have Low Telomerase Activity and High Stem-Like and Invasive Characteristics
Front Oncol, 9, 1302
DOI 10.3389/fonc.2019.01302, PubMed 31921617

Publications 2018

Flem-Karlsen K, Fodstad Ø, Tan M, Nunes-Xavier CE (2018)
B7-H3 in Cancer - Beyond Immune Regulation
Trends Cancer, 4 (6), 401-404
DOI 10.1016/j.trecan.2018.03.010, PubMed 29860983

Saeednejad Zanjani L, Madjd Z, Abolhasani M, Rasti A, Shariftabrizi A, Mehrazma M, Fodstad Ø, Asgari M (2018)
Human telomerase reverse transcriptase protein expression predicts tumour aggressiveness and survival in patients with clear cell renal cell carcinoma
Pathology, 51 (1), 21-31
DOI 10.1016/j.pathol.2018.08.019, PubMed 30466948

Publications 2017

Andersson Y, Haavardtun SI, Davidson B, Dørum A, Fleten KG, Fodstad Ø, Flatmark K (2017)
MOC31PE immunotoxin - targeting peritoneal metastasis from epithelial ovarian cancer
Oncotarget, 8 (37), 61800-61809
DOI 10.18632/oncotarget.18694, PubMed 28977905

Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
Pathol Oncol Res, 25 (1), 255-262
DOI 10.1007/s12253-017-0355-7, PubMed 29098521

Flem-Karlsen K, Tekle C, Andersson Y, Flatmark K, Fodstad Ø, Nunes-Xavier CE (2017)
Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells
Pigment Cell Melanoma Res, 30 (5), 467-476
DOI 10.1111/pcmr.12599, PubMed 28513992

Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Olsen KH, Giercksky KE, Julsrud L, Fodstad Ø, Dueland S, Flatmark K (2017)
Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial
Ann Surg Oncol, 24 (7), 1916-1922
DOI 10.1245/s10434-017-5814-6, PubMed 28224367

Lim S, Phillips JB, Madeira da Silva L, Zhou M, Fodstad O, Owen LB, Tan M (2017)
Interplay between Immune Checkpoint Proteins and Cellular Metabolism
Cancer Res, 77 (6), 1245-1249
DOI 10.1158/0008-5472.CAN-16-1647, PubMed 28246276

Wang MY, Nestvold J, Rekdal Ø, Kvalheim G, Fodstad Ø (2017)
A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties
Exp Cell Res, 352 (2), 218-224
DOI 10.1016/j.yexcr.2017.02.005, PubMed 28189639

Zanjani LS, Madjd Z, Abolhasani M, Rasti A, Fodstad O, Andersson Y, Asgari M (2017)
Increased expression of CD44 is associated with more aggressive behavior in clear cell renal cell carcinoma
Biomark Med, 12 (1), 45-61
DOI 10.2217/bmm-2017-0142, PubMed 29243496

Publications 2016

Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips JB, Schmitt DC, Vu T, McClellan S, Lin Y, Lin W, Piazza GA, Fodstad O, Tan M (2016)
Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α
Cancer Res, 76 (8), 2231-42
DOI 10.1158/0008-5472.CAN-15-1538, PubMed 27197253

Nunes-Xavier CE, Karlsen KF, Tekle C, Pedersen C, Øyjord T, Hongisto V, Nesland JM, Tan M, Sahlberg KK, Fodstad Ø (2016)
Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors
Oncotarget, 7 (6), 6891-901
DOI 10.18632/oncotarget.6902, PubMed 26771843

Rud AK, Boye K, Fodstad Ø, Juell S, Jørgensen LH, Solberg S, Helland Å, Brustugun OT, Mælandsmo GM (2016)
Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer
Diagn Pathol, 11 (1), 50
DOI 10.1186/s13000-016-0504-4, PubMed 27316334

Publications 2015

Andersson Y, Engebraaten O, Juell S, Aamdal S, Brunsvig P, Fodstad Ø, Dueland S (2015)
Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin
Br J Cancer, 113 (11), 1548-55
DOI 10.1038/bjc.2015.380, PubMed 26554649

Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2015)
Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox
Acta Ophthalmol, 93 (1), 59-66
DOI 10.1111/aos.12462, PubMed 25613126

Eide N, Garred Ø, Beiske K, Fodstad Ø (2015)
Bilateral uveal melanomas with different gene expression detected with 7 years interval
Acta Ophthalmol, 94 (1), 99-102
DOI 10.1111/aos.12857, PubMed 26496992

Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K et al. (2015)
Tumour exosome integrins determine organotropic metastasis
Nature, 527 (7578), 329-35
DOI 10.1038/nature15756, PubMed 26524530

Srivastava SK, Bhardwaj A, Arora S, Tyagi N, Singh AP, Carter JE, Scammell JG, Fodstad Ø, Singh S (2015)
Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis
Br J Cancer, 112 (11), 1772-81
DOI 10.1038/bjc.2015.154, PubMed 25942396

Publications 2014

Ingebrigtsen VA, Boye K, Nesland JM, Nesbakken A, Flatmark K, Fodstad Ø (2014)
B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome
BMC Cancer, 14, 602
DOI 10.1186/1471-2407-14-602, PubMed 25139714

Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK (2014)
Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
Br J Cancer, 110 (8), 2072-80
DOI 10.1038/bjc.2014.113, PubMed 24577056

Wiiger MT, Bideli H, Fodstad O, Flatmark K, Andersson Y (2014)
The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells
J Ovarian Res, 7, 23
DOI 10.1186/1757-2215-7-23, PubMed 24528603

Publications 2013

Bruheim S, Sandvold ML, Mælandsmo GM, Fodstad O (2013)
Antitumor activity of elacytarabine combined with bevacizumab, cetuximab and trastuzumab in human NSCLC xenografts
Anticancer Res, 33 (9), 3615-21
PubMed 24023287

Desai S, Liu Z, Yao J, Patel N, Chen J, Wu Y, Ahn EE, Fodstad O, Tan M (2013)
Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)
J Biol Chem, 288 (13), 9165-76
DOI 10.1074/jbc.M112.422071, PubMed 23386620

Flatmark K, Guldvik IJ, Svensson H, Fleten KG, Flørenes VA, Reed W, Giercksky KE, Fodstad Ø, Andersson Y (2013)
Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies
Int J Cancer, 133 (6), 1497-506
DOI 10.1002/ijc.28158, PubMed 23494569

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
Clinical significance of disseminated tumour cells in non-small cell lung cancer
Br J Cancer, 109 (5), 1264-70
DOI 10.1038/bjc.2013.450, PubMed 23942067

Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
PLoS One, 8 (6), e66165
DOI 10.1371/journal.pone.0066165, PubMed 23824282

Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G (2013)
In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
Exp Hematol Oncol, 2 (1), 16
DOI 10.1186/2162-3619-2-16, PubMed 23738757

Zhai H, Fesler A, Schee K, Fodstad O, Flatmark K, Ju J (2013)
Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer
Clin Colorectal Cancer, 12 (4), 261-6
DOI 10.1016/j.clcc.2013.06.003, PubMed 24012455

Publications 2012

Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, LeDoux SP, Wilson GL, Tan M (2012)
Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism
Nat Commun, 3, 1271
DOI 10.1038/ncomms2236, PubMed 23232401

Eide N, Hoifødt HK, Nesland JM, Faye RS, Qvale GA, Faber RT, Jebsen P, Kvalheim G, Fodstad Ø (2012)
Disseminated tumour cells in bone marrow of patients with uveal melanoma
Acta Ophthalmol, 91 (4), 343-8
DOI 10.1111/j.1755-3768.2012.02449.x, PubMed 22632270

Ingebrigtsen VA, Boye K, Tekle C, Nesland JM, Flatmark K, Fodstad O (2012)
B7-H3 expression in colorectal cancer: nuclear localization strongly predicts poor outcome in colon cancer
Int J Cancer, 131 (11), 2528-36
DOI 10.1002/ijc.27566, PubMed 22473715

Liu Z, Liu H, Desai S, Schmitt DC, Zhou M, Khong HT, Klos KS, McClellan S, Fodstad O, Tan M (2012)
miR-125b functions as a key mediator for snail-induced stem cell propagation and chemoresistance
J Biol Chem, 288 (6), 4334-45
DOI 10.1074/jbc.M112.419168, PubMed 23255607

Schee K, Boye K, Abrahamsen TW, Fodstad Ø, Flatmark K (2012)
Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
BMC Cancer, 12, 505
DOI 10.1186/1471-2407-12-505, PubMed 23121918

Vincent AJ, Ren S, Harris LG, Devine DJ, Samant RS, Fodstad O, Shevde LA (2012)
Cytoplasmic translocation of p21 mediates NUPR1-induced chemoresistance: NUPR1 and p21 in chemoresistance
FEBS Lett, 586 (19), 3429-34
DOI 10.1016/j.febslet.2012.07.063, PubMed 22858377

Publications 2011

Bruheim S, Kristian A, Uenaka T, Suo Z, Tsuruoka A, Nesland JM, Fodstad Ø (2011)
Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts
Int J Cancer, 129 (3), 742-50
DOI 10.1002/ijc.25922, PubMed 21225632

Flatmark K, Borgen E, Nesland JM, Rasmussen H, Johannessen HO, Bukholm I, Rosales R, Hårklau L, Jacobsen HJ, Sandstad B, Boye K, Fodstad Ø (2011)
Disseminated tumour cells as a prognostic biomarker in colorectal cancer
Br J Cancer, 104 (9), 1434-9
DOI 10.1038/bjc.2011.97, PubMed 21448171

Hjortland GO, Meza-Zepeda LA, Beiske K, Ree AH, Tveito S, Hoifodt H, Bohler PJ, Hole KH, Myklebost O, Fodstad O, Smeland S, Hovig E (2011)
Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma
BMC Cancer, 11, 455
DOI 10.1186/1471-2407-11-455, PubMed 22014070

Liu H, Tekle C, Chen YW, Kristian A, Zhao Y, Zhou M, Liu Z, Ding Y, Wang B, Mælandsmo GM, Nesland JM, Fodstad O, Tan M (2011)
B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation
Mol Cancer Ther, 10 (6), 960-71
DOI 10.1158/1535-7163.MCT-11-0072, PubMed 21518725

Nygren MK, Tekle C, Ingebrigtsen VA, Fodstad O (2011)
B7-H3 and its relevance in cancer; immunological and non-immunological perspectives
Front Biosci (Elite Ed), 3 (3), 989-93
DOI 10.2741/e304, PubMed 21622107

Risberg K, Fodstad Ø, Andersson Y (2011)
Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma
PLoS One, 6 (9), e24012
DOI 10.1371/journal.pone.0024012, PubMed 21915275

Risberg K, Guldvik IJ, Palchaudhuri R, Xi Y, Ju J, Fodstad O, Hergenrother PJ, Andersson Y (2011)
Triphenylmethyl derivatives enhances the anticancer effect of immunotoxins
J Immunother, 34 (5), 438-47
DOI 10.1097/CJI.0b013e31821e00ae, PubMed 21577141

Saelen MG, Flatmark K, Folkvord S, de Wijn R, Rasmussen H, Fodstad Ø, Ree AH (2011)
Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination
Angiogenesis, 14 (4), 481-9
DOI 10.1007/s10456-011-9231-3, PubMed 21833622

Tekle C, Nygren MK, Chen YW, Dybsjord I, Nesland JM, Maelandsmo GM, Fodstad O (2011)
B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes
Int J Cancer, 130 (10), 2282-90
DOI 10.1002/ijc.26238, PubMed 21671471

Tveito S, Andersen K, Kåresen R, Fodstad Ø (2011)
Analysis of EpCAM positive cells isolated from sentinel lymph nodes of breast cancer patients identifies subpopulations of cells with distinct transcription profiles
Breast Cancer Res, 13 (4), R75
DOI 10.1186/bcr2922, PubMed 21816090

Wang B, Howel P, Bruheim S, Ju J, Owen LB, Fodstad O, Xi Y (2011)
Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array
PLoS One, 6 (2), e17167
DOI 10.1371/journal.pone.0017167, PubMed 21347261

Zhao Y, Liu H, Liu Z, Ding Y, Ledoux SP, Wilson GL, Voellmy R, Lin Y, Lin W, Nahta R, Liu B, Fodstad O, Chen J, Wu Y, Price JE, Tan M (2011)
Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism
Cancer Res, 71 (13), 4585-97
DOI 10.1158/0008-5472.CAN-11-0127, PubMed 21498634

Zhao Y, Liu H, Riker AI, Fodstad O, Ledoux SP, Wilson GL, Tan M (2011)
Emerging metabolic targets in cancer therapy
Front Biosci (Landmark Ed), 16 (5), 1844-60
DOI 10.2741/3826, PubMed 21196269

Publications 2010

Bergman AM, Adema AD, Balzarini J, Bruheim S, Fichtner I, Noordhuis P, Fodstad O, Myhren F, Sandvold ML, Hendriks HR, Peters GJ (2010)
Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models
Invest New Drugs, 29 (3), 456-66
DOI 10.1007/s10637-009-9377-7, PubMed 20066470

Briggs JJ, Haugen MH, Johansen HT, Riker AI, Abrahamson M, Fodstad Ø, Maelandsmo GM, Solberg R (2010)
Cystatin E/M suppresses legumain activity and invasion of human melanoma
BMC Cancer, 10, 17
DOI 10.1186/1471-2407-10-17, PubMed 20074384

Davies ML, Parr C, Sanders AJ, Fodstad O, Jiang WG (2010)
The transcript expression and protein distribution pattern in human colorectal carcinoma reveal a pivotal role of COM-1/p8 as a tumour suppressor
Cancer Genomics Proteomics, 7 (2), 75-80
PubMed 20335521

Mercapide J, Rappa G, Anzanello F, King J, Fodstad O, Lorico A (2010)
Primary gene-engineered neural stem/progenitor cells demonstrate tumor-selective migration and antitumor effects in glioma
Int J Cancer, 126 (5), 1206-15
DOI 10.1002/ijc.24809, PubMed 19653275

Metge BJ, Liu S, Riker AI, Fodstad O, Samant RS, Shevde LA (2010)
Elevated osteopontin levels in metastatic melanoma correlate with epigenetic silencing of breast cancer metastasis suppressor 1
Oncology, 78 (1), 75-86
DOI 10.1159/000292363, PubMed 20215788

Prasmickaite L, Skrbo N, Høifødt HK, Suo Z, Engebråten O, Gullestad HP, Aamdal S, Fodstad Ø, Maelandsmo GM (2010)
Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
Pigment Cell Melanoma Res, 23 (3), 449-51
DOI 10.1111/j.1755-148X.2010.00690.x, PubMed 20236249

Risberg K, Fodstad O, Andersson Y (2010)
Anti-melanoma activity of the 9.2.27PE immunotoxin in dacarbazine resistant cells
J Immunother, 33 (3), 272-8
DOI 10.1097/CJI.0b013e3181c54991, PubMed 20445347

Risberg K, Fodstad O, Andersson Y (2010)
Immunotoxins: a promising treatment modality for metastatic melanoma?
Ochsner J, 10 (3), 193-9
PubMed 21603377

Schee K, Fodstad Ø, Flatmark K (2010)
MicroRNAs as biomarkers in colorectal cancer
Am J Pathol, 177 (4), 1592-9
DOI 10.2353/ajpath.2010.100024, PubMed 20829435

Wiiger MT, Gehrken HB, Fodstad Ø, Maelandsmo GM, Andersson Y (2010)
A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth
Cancer Immunol Immunother, 59 (11), 1665-74
DOI 10.1007/s00262-010-0892-3, PubMed 20635083

Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M (2010)
MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
J Biol Chem, 285 (28), 21496-507
DOI 10.1074/jbc.M109.083337, PubMed 20460378

Zhou M, Zhao Y, Ding Y, Liu H, Liu Z, Fodstad O, Riker AI, Kamarajugadda S, Lu J, Owen LB, Ledoux SP, Tan M (2010)
Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxol
Mol Cancer, 9, 33
DOI 10.1186/1476-4598-9-33, PubMed 20144215

Publications 2009

Andersson Y, Engebraaten O, Fodstad Ø (2009)
Synergistic anti-cancer effects of immunotoxin and cyclosporin in vitro and in vivo
Br J Cancer, 101 (8), 1307-15
DOI 10.1038/sj.bjc.6605312, PubMed 19773757

Bergamaschi A, Hjortland GO, Triulzi T, Sørlie T, Johnsen H, Ree AH, Russnes HG, Tronnes S, Maelandsmo GM, Fodstad O, Borresen-Dale AL, Engebraaten O (2009)
Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
Mol Oncol, 3 (5-6), 469-82
DOI 10.1016/j.molonc.2009.07.003, PubMed 19713161

Bratland A, Boender PJ, Høifødt HK, Østensen IH, Ruijtenbeek R, Wang MY, Berg JP, Lilleby W, Fodstad Ø, Ree AH (2009)
Osteoblast-induced EGFR/ERBB2 signaling in androgen-sensitive prostate carcinoma cells characterized by multiplex kinase activity profiling
Clin Exp Metastasis, 26 (5), 485-96
DOI 10.1007/s10585-009-9248-9, PubMed 19294521

Bruheim S, Xi Y, Ju J, Fodstad O (2009)
Gene expression profiles classify human osteosarcoma xenografts according to sensitivity to doxorubicin, cisplatin, and ifosfamide
Clin Cancer Res, 15 (23), 7161-9
DOI 10.1158/1078-0432.CCR-08-2816, PubMed 19920113

Bruland ØS, Høifødt H, Hall KS, Smeland S, Fodstad Ø (2009)
Bone marrow micrometastases studied by an immunomagnetic isolation procedure in extremity localized non-metastatic osteosarcoma patients
Cancer Treat Res, 152, 509-15
DOI 10.1007/978-1-4419-0284-9_30, PubMed 20213412

Chowdhury UR, Samant RS, Fodstad O, Shevde LA (2009)
Emerging role of nuclear protein 1 (NUPR1) in cancer biology
Cancer Metastasis Rev, 28 (1-2), 225-32
DOI 10.1007/s10555-009-9183-x, PubMed 19153668

Eide N, Faye RS, Høifødt HK, Øvergaard R, Jebsen P, Kvalheim G, Fodstad Ø (2009)
Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients
Acta Ophthalmol, 87 (8), 830-6
DOI 10.1111/j.1755-3768.2008.01378.x, PubMed 19055657

Engebraaten O, Trikha M, Juell S, Garman-Vik S, Fodstad Ø (2009)
Inhibition of in vivo tumour growth by the blocking of host alpha(v)beta3 and alphaII(b)beta3 integrins
Anticancer Res, 29 (1), 131-7
PubMed 19331142

Howell PM, Liu S, Ren S, Behlen C, Fodstad O, Riker AI (2009)
Epigenetics in human melanoma
Cancer Control, 16 (3), 200-18
DOI 10.1177/107327480901600302, PubMed 19556960

Liu S, Howell P, Ren S, Fodstad O, Riker AI (2009)
The 14-3-3sigma gene promoter is methylated in both human melanocytes and melanoma
BMC Cancer, 9, 162
DOI 10.1186/1471-2407-9-162, PubMed 19473536

Liu S, Howell P, Ren S, Fodstad O, Zhang G, Samant R, Shevde L, Xi Y, Pannell LK, Riker AI (2009)
Expression and functional analysis of the WAP four disulfide core domain 1 gene in human melanoma
Clin Exp Metastasis, 26 (7), 739-49
DOI 10.1007/s10585-009-9273-8, PubMed 19488830

Ren S, Liu S, Howell PM, Zhang G, Pannell L, Samant R, Shevde-Samant L, Tucker JA, Fodstad O, Riker AI (2009)
Functional characterization of the progestagen-associated endometrial protein gene in human melanoma
J Cell Mol Med, 14 (6B), 1432-42
DOI 10.1111/j.1582-4934.2009.00922.x, PubMed 19799645

Risberg K, Fodstad Ø, Andersson Y (2009)
The melanoma specific 9.2.27PE immunotoxin efficiently kills melanoma cells in vitro
Int J Cancer, 125 (1), 23-33
DOI 10.1002/ijc.24317, PubMed 19350633

Song B, Wang Y, Xi Y, Kudo K, Bruheim S, Botchkina GI, Gavin E, Wan Y, Formentini A, Kornmann M, Fodstad O, Ju J (2009)
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells
Oncogene, 28 (46), 4065-74
DOI 10.1038/onc.2009.274, PubMed 19734943

Zhao YH, Zhou M, Liu H, Ding Y, Khong HT, Yu D, Fodstad O, Tan M (2009)
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth
Oncogene, 28 (42), 3689-701
DOI 10.1038/onc.2009.229, PubMed 19668225

Publications 2008

Brunsvig PF, Flatmark K, Aamdal S, Høifødt H, Le H, Jakobsen E, Sandstad B, Fodstad O (2008)
Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients
Lung Cancer, 61 (2), 170-6
DOI 10.1016/j.lungcan.2007.12.018, PubMed 18261824

Chen YW, Tekle C, Fodstad O (2008)
The immunoregulatory protein human B7H3 is a tumor-associated antigen that regulates tumor cell migration and invasion
Curr Cancer Drug Targets, 8 (5), 404-13
DOI 10.2174/156800908785133141, PubMed 18690846

Clark DW, Mitra A, Fillmore RA, Jiang WG, Samant RS, Fodstad O, Shevde LA (2008)
NUPR1 interacts with p53, transcriptionally regulates p21 and rescues breast epithelial cells from doxorubicin-induced genotoxic stress
Curr Cancer Drug Targets, 8 (5), 421-30
DOI 10.2174/156800908785133196, PubMed 18690848

Faye RS, Paus E, Maelandsmo GM, Berner A, Høifødt HK, Fodstad Ø, Aamdal S (2008)
S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
Melanoma Res, 18 (2), 134-40
DOI 10.1097/CMR.0b013e3282f623d9, PubMed 18337650

Lorico A, Mercapide J, Solodushko V, Alexeyev M, Fodstad O, Rappa G (2008)
Primary neural stem/progenitor cells expressing endostatin or cytochrome P450 for gene therapy of glioblastoma
Cancer Gene Ther, 15 (9), 605-15
DOI 10.1038/cgt.2008.23, PubMed 18421309

Nakajima G, Patino-Garcia A, Bruheim S, Xi Y, San Julian M, Lecanda F, Sierrasesumaga L, Müller C, Fodstad O, Ju J (2008)
CDH11 expression is associated with survival in patients with osteosarcoma
Cancer Genomics Proteomics, 5 (1), 37-42
PubMed 18359978

Rappa G, Fodstad O, Lorico A (2008)
The stem cell-associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma
Stem Cells, 26 (12), 3008-17
DOI 10.1634/stemcells.2008-0601, PubMed 18802032

Rappa G, Mercapide J, Anzanello F, Prasmickaite L, Xi Y, Ju J, Fodstad O, Lorico A (2008)
Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets
Exp Cell Res, 314 (10), 2110-22
DOI 10.1016/j.yexcr.2008.03.008, PubMed 18423605

Riker AI, Enkemann SA, Fodstad O, Liu S, Ren S, Morris C, Xi Y, Howell P, Metge B, Samant RS, Shevde LA, Li W, Eschrich S, Daud A, Ju J, Matta J (2008)
The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis
BMC Med Genomics, 1, 13
DOI 10.1186/1755-8794-1-13, PubMed 18442402

Xi Y, Riker A, Shevde-Samant L, Samant R, Morris C, Gavin E, Fodstad O, Ju J (2008)
Global comparative gene expression analysis of melanoma patient samples, derived cell lines and corresponding tumor xenografts
Cancer Genomics Proteomics, 5 (1), 1-35
PubMed 18359977

Publications 2007

Bauer NN, Chen YW, Samant RS, Shevde LA, Fodstad O (2007)
Rac1 activity regulates proliferation of aggressive metastatic melanoma
Exp Cell Res, 313 (18), 3832-9
DOI 10.1016/j.yexcr.2007.08.017, PubMed 17904119

Flatmark K, Reed W, Halvorsen T, Sørensen O, Wiig JN, Larsen SG, Fodstad Ø, Giercksky KE (2007)
Pseudomyxoma peritonei--two novel orthotopic mouse models portray the PMCA-I histopathologic subtype
BMC Cancer, 7, 116
DOI 10.1186/1471-2407-7-116, PubMed 17603904

Fodstad Ø (2007)
[The 75th anniversary of the Radium Hospital]
Tidsskr Nor Laegeforen, 127 (13), 1800-1
PubMed 17599133

Fodstad Ø, Jiang WG, Mansel RE (2007)
Metastasis of breast cancer
Springer, Dordrecht, XIV, 435 s.
BIBSYS 070516383, ISBN 978-1-4020-5866-0

Lillehammer T, Engesaeter BO, Prasmickaite L, Maelandsmo GM, Fodstad O, Engebraaten O (2007)
Combined treatment with Ad-hTRAIL and DTIC or SAHA is associated with increased mitochondrial-mediated apoptosis in human melanoma cell lines
J Gene Med, 9 (6), 440-51
DOI 10.1002/jgm.1036, PubMed 17410615

Liu S, Ren S, Howell P, Fodstad O, Riker AI (2007)
Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling
Pigment Cell Melanoma Res, 21 (5), 545-58
DOI 10.1111/j.1755-148X.2008.00484.x, PubMed 18627528

Rappa G, Anzanello F, Alexeyev M, Fodstad O, Lorico A (2007)
Gamma-glutamylcysteine synthetase-based selection strategy for gene therapy of chronic granulomatous disease and graft-vs.-host disease
Eur J Haematol, 78 (5), 440-8
DOI 10.1111/j.1600-0609.2007.00833.x, PubMed 17331133

Thies A, Mauer S, Fodstad O, Schumacher U (2007)
Clinically proven markers of metastasis predict metastatic spread of human melanoma cells engrafted in scid mice
Br J Cancer, 96 (4), 609-16
DOI 10.1038/sj.bjc.6603594, PubMed 17262079

Tveito S, Maelandsmo GM, Hoifodt HK, Rasmussen H, Fodstad O (2007)
Specific isolation of disseminated cancer cells: a new method permitting sensitive detection of target molecules of diagnostic and therapeutic value
Clin Exp Metastasis, 24 (5), 317-27
DOI 10.1007/s10585-006-9052-8, PubMed 17530423

Publications 2006

Andersson Y, Le H, Juell S, Fodstad Ø (2006)
AMP-activated protein kinase protects against anti-epidermal growth factor receptor-Pseudomonas exotoxin A immunotoxin-induced MA11 breast cancer cell death
Mol Cancer Ther, 5 (4), 1050-9
DOI 10.1158/1535-7163.MCT-05-0318, PubMed 16648577

Flatmark K, Nome RV, Folkvord S, Bratland A, Rasmussen H, Ellefsen MS, Fodstad Ø, Ree AH (2006)
Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition
Radiat Oncol, 1, 25
DOI 10.1186/1748-717X-1-25, PubMed 16887021

Jiang WG, Davies G, Kynaston H, Mason MD, Fodstad O (2006)
Does the PGC-1/PPARgamma pathway play a role in Com-1/p8 mediated cell growth inhibition in prostate cancer?
Int J Mol Med, 18 (6), 1169-75
PubMed 17089023

Jiang WG, Davies G, Martin TA, Kynaston H, Mason MD, Fodstad O (2006)
Com-1/p8 acts as a putative tumour suppressor in prostate cancer
Int J Mol Med, 18 (5), 981-6
PubMed 17016631

Mbeunkui F, Fodstad O, Pannell LK (2006)
Secretory protein enrichment and analysis: an optimized approach applied on cancer cell lines using 2D LC-MS/MS
J Proteome Res, 5 (4), 899-906
DOI 10.1021/pr050375p, PubMed 16602697

Ree AH, Stokke T, Bratland A, Patzke S, Nome RV, Folkvord S, Meza-Zepeda LA, Flatmark K, Fodstad O, Andersson Y (2006)
DNA damage responses in cell cycle G2 phase and mitosis--tracking and targeting
Anticancer Res, 26 (3A), 1909-16
PubMed 16827124

Xi Y, Nakajima G, Hamil T, Fodstad O, Riker A, Ju J (2006)
Association of insulin-like growth factor binding protein-3 expression with melanoma progression
Mol Cancer Ther, 5 (12), 3078-84
DOI 10.1158/1535-7163.MCT-06-0424, PubMed 17172410

Xi Y, Shalgi R, Fodstad O, Pilpel Y, Ju J (2006)
Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer
Clin Cancer Res, 12 (7 Pt 1), 2014-24
DOI 10.1158/1078-0432.CCR-05-1853, PubMed 16609010

Publications 2005

Bjørnland K, Flatmark K, Pettersen S, Aaasen AO, Fodstad O, Maelandsmo GM (2005)
Matrix metalloproteinases participate in osteosarcoma invasion
J Surg Res, 127 (2), 151-6
DOI 10.1016/j.jss.2004.12.016, PubMed 16083752

Bruland OS, Høifødt H, Saeter G, Smeland S, Fodstad O (2005)
Hematogenous micrometastases in osteosarcoma patients
Clin Cancer Res, 11 (13), 4666-73
DOI 10.1158/1078-0432.CCR-05-0165, PubMed 16000559

Engesaeter BØ, Bonsted A, Berg K, Høgset A, Engebråten O, Fodstad Ø, Curiel DT, Maelandsmo GM (2005)
PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles
Cancer Gene Ther, 12 (5), 439-48
DOI 10.1038/sj.cgt.7700808, PubMed 15678152

Jiang WG, Davies G, Fodstad O (2005)
Com-1/P8 in oestrogen regulated growth of breast cancer cells, the ER-beta connection
Biochem Biophys Res Commun, 330 (1), 253-62
DOI 10.1016/j.bbrc.2005.02.157, PubMed 15781258

Jiang WG, Watkins G, Douglas-Jones A, Mokbel K, Mansel RE, Fodstad O (2005)
Expression of Com-1/P8 in human breast cancer and its relevance to clinical outcome and ER status
Int J Cancer, 117 (5), 730-7
DOI 10.1002/ijc.21221, PubMed 15957166

Lillehammer T, Tveito S, Engesaeter BO, Fodstad O, Maelandsmo GM, Engebraaten O (2005)
Melanoma-specific expression in first-generation adenoviral vectors in vitro and in vivo -- use of the human tyrosinase promoter with human enhancers
Cancer Gene Ther, 12 (11), 864-72
DOI 10.1038/sj.cgt.7700852, PubMed 15891771

Lorico A, Bratbak D, Meyer J, Kunke D, Krauss S, Plott WE, Solodushko V, Baum C, Fodstad O, Rappa G (2005)
Gamma-glutamylcysteine synthetase and L-buthionine-(S,R)-sulfoximine: a new selection strategy for gene-transduced neural and hematopoietic stem/progenitor cells
Hum Gene Ther, 16 (6), 711-24
DOI 10.1089/hum.2005.16.711, PubMed 15960602

Lund T, Stokke T, Olsen ØE, Fodstad Ø (2005)
Garlic arrests MDA-MB-435 cancer cells in mitosis, phosphorylates the proapoptotic BH3-only protein BimEL and induces apoptosis
Br J Cancer, 92 (9), 1773-81
DOI 10.1038/sj.bjc.6602537, PubMed 15827557

Nome RV, Bratland A, Harman G, Fodstad O, Andersson Y, Ree AH (2005)
Cell cycle checkpoint signaling involved in histone deacetylase inhibition and radiation-induced cell death
Mol Cancer Ther, 4 (8), 1231-8
DOI 10.1158/1535-7163.MCT-04-0304, PubMed 16093439

Publications 2004

Andersen K, Nesland JM, Holm R, Flørenes VA, Fodstad Ø, Maelandsmo GM (2004)
Expression of S100A4 combined with reduced E-cadherin expression predicts patient outcome in malignant melanoma
Mod Pathol, 17 (8), 990-7
DOI 10.1038/modpathol.3800151, PubMed 15133476

Andersson Y, Juell S, Fodstad Ø (2004)
Downregulation of the antiapoptotic MCL-1 protein and apoptosis in MA-11 breast cancer cells induced by an anti-epidermal growth factor receptor-Pseudomonas exotoxin a immunotoxin
Int J Cancer, 112 (3), 475-83
DOI 10.1002/ijc.20371, PubMed 15382075

Bergman AM, Kuiper CM, Noordhuis P, Smid K, Voorn DA, Comijn EM, Myhren F, Sandvold ML, Hendriks HR, Fodstad O, Breistøl K, Peters GJ (2004)
Antiproliferative activity and mechanism of action of fatty acid derivatives of gemcitabine in leukemia and solid tumor cell lines and in human xenografts
Nucleosides Nucleotides Nucleic Acids, 23 (8-9), 1329-33
DOI 10.1081/NCN-200027579, PubMed 15571253

Bruheim S, Bruland OS, Breistol K, Maelandsmo GM, Fodstad O (2004)
Human osteosarcoma xenografts and their sensitivity to chemotherapy
Pathol Oncol Res, 10 (3), 133-41
DOI 10.1007/BF03033741, PubMed 15448748

Faye RS, Aamdal S, Høifødt HK, Jacobsen E, Holstad L, Skovlund E, Fodstad Ø (2004)
Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients
Clin Cancer Res, 10 (12 Pt 1), 4134-9
DOI 10.1158/1078-0432.CCR-03-0408, PubMed 15217950

Flatmark K, Maelandsmo GM, Martinsen M, Rasmussen H, Fodstad Ø (2004)
Twelve colorectal cancer cell lines exhibit highly variable growth and metastatic capacities in an orthotopic model in nude mice
Eur J Cancer, 40 (10), 1593-8
DOI 10.1016/j.ejca.2004.02.023, PubMed 15196545

Flatmark K, Maelandsmo GM, Mikalsen SO, Nustad K, Varaas T, Rasmussen H, Meling GI, Fodstad Ø, Paus E (2004)
Immunofluorometric assay for the metastasis-related protein S100A4: release of S100A4 from normal blood cells prohibits the use of S100A4 as a tumor marker in plasma and serum
Tumour Biol, 25 (1-2), 31-40
DOI 10.1159/000077721, PubMed 15192310

Hjortland GO, Garman-Vik SS, Juell S, Olsen OE, Hirschberg H, Fodstad O, Engebraaten O (2004)
Immunotoxin treatment targeted to the high-molecular-weight melanoma-associated antigen prolonging the survival of immunodeficient rats with invasive intracranial human glioblastoma multiforme
J Neurosurg, 100 (2), 320-7
DOI 10.3171/jns.2004.100.2.0320, PubMed 15086240

Hjortland GO, Lillehammer T, Somme S, Wang J, Halvorsen T, Juell S, Hirschberg H, Fodstad Ø, Engebraaten O (2004)
Plasminogen activator inhibitor-1 increases the expression of VEGF in human glioma cells
Exp Cell Res, 294 (1), 130-9
DOI 10.1016/j.yexcr.2003.10.013, PubMed 14980508

Jiang WG, Watkins G, Fodstad O, Douglas-Jones A, Mokbel K, Mansel RE (2004)
Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer
Endocr Relat Cancer, 11 (4), 781-91
DOI 10.1677/erc.1.00825, PubMed 15613452

King JA, Ofori-Acquah SF, Stevens T, Al-Mehdi AB, Fodstad O, Jiang WG (2004)
Activated leukocyte cell adhesion molecule in breast cancer: prognostic indicator
Breast Cancer Res, 6 (5), R478-87
DOI 10.1186/bcr815, PubMed 15318930

Pedersen KB, Andersen K, Fodstad Ø, Maelandsmo GM (2004)
Sensitization of interferon-gamma induced apoptosis in human osteosarcoma cells by extracellular S100A4
BMC Cancer, 4, 52
DOI 10.1186/1471-2407-4-52, PubMed 15318945

Rappa G, Kunke D, Holter J, Diep DB, Meyer J, Baum C, Fodstad O, Krauss S, Lorico A (2004)
Efficient expansion and gene transduction of mouse neural stem/progenitor cells on recombinant fibronectin
Neuroscience, 124 (4), 823-30
DOI 10.1016/j.neuroscience.2003.11.030, PubMed 15026123

Ree AH, Bratland A, Nome RV, Stokke T, Fodstad O, Andersson Y (2004)
Inhibitory targeting of checkpoint kinase signaling overrides radiation-induced cell cycle gene regulation: a therapeutic strategy in tumor cell radiosensitization?
Radiother Oncol, 72 (3), 305-10
DOI 10.1016/j.radonc.2004.07.002, PubMed 15450729

Ree AH, Bratland A, Solberg Landsverk K, Fodstad O (2004)
Ionizing radiation inhibits the PLK cell cycle gene in a G2 checkpoint-dependent manner
Anticancer Res, 24 (2B), 555-62
PubMed 15160994

Wang X, Wang M, Amarzguioui M, Liu F, Fodstad Ø, Prydz H (2004)
Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
Int J Cancer, 112 (6), 994-1002
DOI 10.1002/ijc.20527, PubMed 15386437

Publications 2003

Andersen K, Smith-Sørensen B, Pedersen KB, Hovig E, Myklebost O, Fodstad Ø, Maelandsmo GM (2003)
Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest
Br J Cancer, 88 (12), 1995-2001
DOI 10.1038/sj.bjc.6600998, PubMed 12799648

Bjørnland K, Flatmark K, Mala T, Mathisen O, Bakka A, Aasen AO, Bergan A, Søreide O, Fodstad O (2003)
Detection of disseminated tumour cells in bone marrow of patients with isolated liver metastases from colorectal cancer
J Surg Oncol, 82 (4), 224-7
DOI 10.1002/jso.10223, PubMed 12672004

Bratland A, Ragnhildstveit E, Bjørnland K, Andersen K, Maelandsmo GM, Fodstad O, Saatcioglu F, Ree AH (2003)
The metalloproteinase inhibitor TIMP-2 is down-regulated by androgens in LNCaP prostate carcinoma cells
Clin Exp Metastasis, 20 (6), 541-7
DOI 10.1023/a:1025860214891, PubMed 14598888

Flatmark K, Pedersen KB, Nesland JM, Rasmussen H, Aamodt G, Mikalsen SO, Bjørnland K, Fodstad Ø, Maelandsmo GM (2003)
Nuclear localization of the metastasis-related protein S100A4 correlates with tumour stage in colorectal cancer
J Pathol, 200 (5), 589-95
DOI 10.1002/path.1381, PubMed 12898594

Hjortland GO, Bjørnland K, Pettersen S, Garman-Vik SS, Emilsen E, Nesland JM, Fodstad O, Engebraaten O (2003)
Modulation of glioma cell invasion and motility by adenoviral gene transfer of PAI-1
Clin Exp Metastasis, 20 (4), 301-9
DOI 10.1023/a:1024040718238, PubMed 12856717

Maelandsmo GM, Holm R, Nesland JM, Fodstad Ø, Flørenes VA (2003)
Reduced beta-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma
Clin Cancer Res, 9 (9), 3383-8
PubMed 12960126

Mathisen B, Lindstad RI, Hansen J, El-Gewely SA, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO (2003)
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells
Clin Exp Metastasis, 20 (8), 701-11
DOI 10.1023/b:clin.0000006819.21361.03, PubMed 14713104

Nygaard V, Løland A, Holden M, Langaas M, Rue H, Liu F, Myklebost O, Fodstad Ø, Hovig E, Smith-Sørensen B (2003)
Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
BMC Genomics, 4 (1), 11
DOI 10.1186/1471-2164-4-11, PubMed 12659661

Rappa G, Gamcsik MP, Mitina RL, Baum C, Fodstad O, Lorico A (2003)
Retroviral transfer of MRP1 and gamma-glutamyl cysteine synthetase modulates cell sensitivity to L-buthionine-S,R-sulphoximine (BSO): new rationale for the use of BSO in cancer therapy
Eur J Cancer, 39 (1), 120-8
DOI 10.1016/s0959-8049(02)00447-1, PubMed 12504668

Ree AH, Bratland A, Nome RV, Stokke T, Fodstad Ø (2003)
Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1
Oncogene, 22 (55), 8952-5
DOI 10.1038/sj.onc.1207000, PubMed 14654792

Publications 2002

Engebraaten O, Hjortland GO, Juell S, Hirschberg H, Fodstad O (2002)
Intratumoral immunotoxin treatment of human malignant brain tumors in immunodeficient animals
Int J Cancer, 97 (6), 846-52
DOI 10.1002/ijc.10137, PubMed 11857366

Flatmark K, Bjørnland K, Johannessen HO, Hegstad E, Rosales R, Hårklau L, Solhaug JH, Faye RS, Søreide O, Fodstad Ø, Study Group for Micrometastases in BM in Colorectal Cancer (2002)
Immunomagnetic detection of micrometastatic cells in bone marrow of colorectal cancer patients
Clin Cancer Res, 8 (2), 444-9
PubMed 11839662

Henriksen G, Breistøl K, Bruland ØS, Fodstad Ø, Larsen RH (2002)
Significant antitumor effect from bone-seeking, alpha-particle-emitting (223)Ra demonstrated in an experimental skeletal metastases model
Cancer Res, 62 (11), 3120-5
PubMed 12036923

Høgset A, Engesaeter BO, Prasmickaite L, Berg K, Fodstad O, Maelandsmo GM (2002)
Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy
Cancer Gene Ther, 9 (4), 365-71
DOI 10.1038/sj.cgt.7700447, PubMed 11960287

Lorico A, Bertola A, Baum C, Fodstad O, Rappa G (2002)
Role of the Multidrug Resistance Protein 1 in protection from heavy metal oxyanions: investigations in vitro and in MRP1-deficient mice
Biochem Biophys Res Commun, 291 (3), 617-22
DOI 10.1006/bbrc.2002.6489, PubMed 11855834

Lorico A, Nesland J, Emilsen E, Fodstad O, Rappa G (2002)
Role of the multidrug resistance protein 1 gene in the carcinogenicity of aflatoxin B1: investigations using mrp1-null mice
Toxicology, 171 (2-3), 201-5
DOI 10.1016/s0300-483x(01)00584-4, PubMed 11836025

Marth C, Kisic J, Kaern J, Tropé C, Fodstad Ø (2002)
Circulating tumor cells in the peripheral blood and bone marrow of patients with ovarian carcinoma do not predict prognosis
Cancer, 94 (3), 707-12
DOI 10.1002/cncr.10250, PubMed 11857303

Pedersen KB, Nesland JM, Fodstad Ø, Maelandsmo GM (2002)
Expression of S100A4, E-cadherin, alpha- and beta-catenin in breast cancer biopsies
Br J Cancer, 87 (11), 1281-6
DOI 10.1038/sj.bjc.6600624, PubMed 12439718

Ree AH, Bratland A, Kroes RA, Aasheim HC, Flørenes VA, Moskal JR, Fodstad O, Bruland OS, Maelandsmo GM (2002)
Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases
Anticancer Res, 22 (4), 1949-57
PubMed 12174869

Ree AH, Engebraaten O, Hovig E, Fodstad Ø (2002)
Differential display analysis of breast carcinoma cells enriched by immunomagnetic target cell selection: gene expression profiles in bone marrow target cells
Int J Cancer, 97 (1), 28-33
DOI 10.1002/ijc.1564, PubMed 11774240

Smith-Sørensen B, Lind GE, Skotheim RI, Fosså SD, Fodstad Ø, Stenwig AE, Jakobsen KS, Lothe RA (2002)
Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
Oncogene, 21 (57), 8878-84
DOI 10.1038/sj.onc.1205978, PubMed 12483540

Publications 2001

Bjørnland K, Bratland A, Rugnes E, Pettersen S, Johansen HT, Aasen AO, Fodstad Ø, Ree AH, Maelandsmo GM (2001)
Expression of matrix metalloproteinases and the metastasis-associated gene S100A4 in human neuroblastoma and primitive neuroectodermal tumor cells
J Pediatr Surg, 36 (7), 1040-4
DOI 10.1053/jpsu.2001.24735, PubMed 11431772

Fodstad O, Faye R, Høifødt HK, Skovlund E, Aamdal S (2001)
Immunobead-based detection and characterization of circulating tumor cells in melanoma patients
Recent Results Cancer Res, 158, 40-50
DOI 10.1007/978-3-642-59537-0_5, PubMed 11092032

Forus A, D'Angelo A, Henriksen J, Merla G, Maelandsmo GM, Flørenes VA, Olivieri S, Bjerkehagen B, Meza-Zepeda LA, del Vecchio Blanco F, Müller C, Sanvito F, Kononen J, Nesland JM, Fodstad Ø, Reymond A, Kallioniemi OP, Arrigoni G, Ballabio A, Myklebost O, Zollo M (2001)
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity
Oncogene, 20 (47), 6881-90
DOI 10.1038/sj.onc.1204874, PubMed 11687967

Hovig E, Maelandsmo G, Mellingsaeter T, Fodstad O, Mielewczyk SS, Wolfe J, Goodchild J (2001)
Optimization of hammerhead ribozymes for the cleavage of S100A4 (CAPL) mRNA
Antisense Nucleic Acid Drug Dev, 11 (2), 67-75
DOI 10.1089/108729001750171272, PubMed 11334142

Ivanov VN, Fodstad O, Ronai Z (2001)
Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities
Oncogene, 20 (18), 2243-53
DOI 10.1038/sj.onc.1204314, PubMed 11402319

Rappa G, Lorico A, Hildinger M, Fodstad Ø, Baum C (2001)
Novel bicistronic retroviral vector expressing gamma-glutamylcysteine synthetase and the multidrug resistance protein 1 (MRP1) protects cells from MRP1-effluxed drugs and alkylating agents
Hum Gene Ther, 12 (14), 1785-96
DOI 10.1089/104303401750476276, PubMed 11560771

Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2001)
In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
Int J Cancer, 92 (5), 761-6
DOI 10.1002/1097-0215(20010601)92:5<761::aid-ijc1238>3.0.co;2-4, PubMed 11340584

Siewert C, Herber M, Hunzelmann N, Fodstad O, Miltenyi S, Assenmacher M, Schmitz J (2001)
Rapid enrichment and detection of melanoma cells from peripheral blood mononuclear cells by a new assay combining immunomagnetic cell sorting and immunocytochemical staining
Recent Results Cancer Res, 158, 51-60
DOI 10.1007/978-3-642-59537-0_6, PubMed 11092033

Publications 2000

Bratland A, Risberg K, Maelandsmo GM, Gützkow KB, Olsen OE, Moghaddam A, Wang MY, Hansen CM, Blomhoff HK, Berg JP, Fodstad O, Ree AH (2000)
Expression of a novel factor, com1, is regulated by 1,25-dihydroxyvitamin D3 in breast cancer cells
Cancer Res, 60 (19), 5578-83
PubMed 11034106

Engebraaten O, Sivam G, Juell S, Fodstad O (2000)
Systemic immunotoxin treatment inhibits formation of human breast cancer metastasis and tumor growth in nude rats
Int J Cancer, 88 (6), 970-6
DOI 10.1002/1097-0215(20001215)88:6<970::aid-ijc21>3.0.co;2-q, PubMed 11093823

Rappa G, Shyam K, Lorico A, Fodstad O, Sartorelli AC (2000)
Structure-activity studies of novobiocin analogs as modulators of the cytotoxicity of etoposide (VP-16)
Oncol Res, 12 (3), 113-9
DOI 10.3727/096504001108747585, PubMed 11216669

Ree AH, Pacheco MM, Tvermyr M, Fodstad O, Brentani MM (2000)
Expression of a novel factor, com1, in early tumor progression of breast cancer
Clin Cancer Res, 6 (5), 1778-83
PubMed 10815897

Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2000)
Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
Int J Cancer, 87 (6), 853-9
DOI 10.1002/1097-0215(20000915)87:6<853::aid-ijc15>3.0.co;2-0, PubMed 10956397

Publications 1999

Berg K, Selbo PK, Prasmickaite L, Tjelle TE, Sandvig K, Moan J, Gaudernack G, Fodstad O, Kjølsrud S, Anholt H, Rodal GH, Rodal SK, Høgset A (1999)
Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
Cancer Res, 59 (6), 1180-3
PubMed 10096543

Bjørnland K, Winberg JO, Odegaard OT, Hovig E, Loennechen T, Aasen AO, Fodstad O, Maelandsmo GM (1999)
S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme
Cancer Res, 59 (18), 4702-8
PubMed 10493528

Borgen E, Naume B, Nesland JM, Kvalheim G, Beiske K, Fodstad O, Diel I, Solomayer EF, Theocharous P, Coombes RC, Smith BM, Wunder E, Marolleau JP, Garcia J, Pantel K (1999)
Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells
Cytotherapy, 1 (5), 377-88
DOI 10.1080/0032472031000141283, PubMed 20426539

Breistøl K, Balzarini J, Sandvold ML, Myhren F, Martinsen M, De Clercq E, Fodstad O (1999)
Antitumor activity of P-4055 (elaidic acid-cytarabine) compared to cytarabine in metastatic and s.c. human tumor xenograft models
Cancer Res, 59 (12), 2944-9
PubMed 10383159

Breistøl K, Hendriks HR, Fodstad O (1999)
Superior therapeutic efficacy of N-L-leucyl-doxorubicin versus doxorubicin in human melanoma xenografts correlates with higher tumour concentrations of free drug
Eur J Cancer, 35 (7), 1143-9
DOI 10.1016/s0959-8049(99)00074-x, PubMed 10533461

Engebraaten O, Fodstad O (1999)
Site-specific experimental metastasis patterns of two human breast cancer cell lines in nude rats
Int J Cancer, 82 (2), 219-25
DOI 10.1002/(sici)1097-0215(19990719)82:2<219::aid-ijc12>3.0.co;2-#, PubMed 10389756

Engebraaten O, Hjortland GO, Hirschberg H, Fodstad O (1999)
Growth of precultured human glioma specimens in nude rat brain
J Neurosurg, 90 (1), 125-32
DOI 10.3171/jns.1999.90.1.0125, PubMed 10413165

Forus A, Høifødt HK, Overli GE, Myklebost O, Fodstad O (1999)
Sensitive fluorescent in situ hybridisation method for the characterisation of breast cancer cells in bone marrow aspirates
Mol Pathol, 52 (2), 68-74
DOI 10.1136/mp.52.2.68, PubMed 10474684

Pantel K, Cote RJ, Fodstad O (1999)
Detection and clinical importance of micrometastatic disease
J Natl Cancer Inst, 91 (13), 1113-24
DOI 10.1093/jnci/91.13.1113, PubMed 10393719

Ree AH, Tvermyr M, Engebraaten O, Rooman M, Røsok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O (1999)
Expression of a novel factor in human breast cancer cells with metastatic potential
Cancer Res, 59 (18), 4675-80
PubMed 10493524

Ruud P, Fodstad O, Hovig E (1999)
Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells
Int J Cancer, 80 (1), 119-25
DOI 10.1002/(sici)1097-0215(19990105)80:1<119::aid-ijc22>3.0.co;2-x, PubMed 9935241

Publications 1998

Andersen K, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO (1998)
Interleukin-1 alpha and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL
Anticancer Res, 18 (5A), 3299-303
PubMed 9858899

Bjørnland K, Lehne G, Johansen HT, Fodstad O, Rugstad HE, Aasen AO, Ree AH (1998)
Human hepatoma cells rich in P-glycoprotein display enhanced in vitro invasive properties compared to P-glycoprotein-poor hepatoma cells
Oncol Res, 10 (5), 255-62
PubMed 9802060

Breistøl K, Hendriks HR, Berger DP, Langdon SP, Fiebig HH, Fodstad O (1998)
The antitumour activity of the prodrug N-L-leucyl-doxorubicin and its parent compound doxorubicin in human tumour xenografts
Eur J Cancer, 34 (10), 1602-6
DOI 10.1016/s0959-8049(98)00152-x, PubMed 9893636

Forus A, Berner JM, Meza-Zepeda LA, Saeter G, Mischke D, Fodstad O, Myklebost O (1998)
Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas
Br J Cancer, 78 (4), 495-503
DOI 10.1038/bjc.1998.521, PubMed 9716033

Prasmickaite L, Hogset A, Maelandsmo G, Berg K, Goodchild J, Perkins T, Fodstad O, Hovig E (1998)
Intracellular metabolism of a 2'-O-methyl-stabilized ribozyme after uptake by DOTAP transfection or asfree ribozyme. A study by capillary electrophoresis
Nucleic Acids Res, 26 (18), 4241-8
DOI 10.1093/nar/26.18.4241, PubMed 9722645

Ree AH, Bjørnland K, Brünner N, Johansen HT, Pedersen KB, Aasen AO, Fodstad O (1998)
Regulation of tissue-degrading factors and in vitro invasiveness in progression of breast cancer cells
Clin Exp Metastasis, 16 (3), 205-15
DOI 10.1023/a:1006584624061, PubMed 9568638

Rye PD, Fodstad O, Emilsen E, Bryne M (1998)
Invasion potential and N-acetylgalactosamine expression in a human melanoma model
Int J Cancer, 75 (4), 609-14
DOI 10.1002/(sici)1097-0215(19980209)75:4<609::aid-ijc19>3.0.co;2-3, PubMed 9466664

Publications 1997

Berner JM, Meza-Zepeda LA, Kools PF, Forus A, Schoenmakers EF, Van de Ven WJ, Fodstad O, Myklebost O (1997)
HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas
Oncogene, 14 (24), 2935-41
DOI 10.1038/sj.onc.1201135, PubMed 9205100

de Graaf H, Maelandsmo GM, Ruud P, Forus A, Oyjord T, Fodstad O, Hovig E (1997)
Ectopic expression of target genes may represent an inherent limitation of RT-PCR assays used for micrometastasis detection: studies on the epithelial glycoprotein gene EGP-2
Int J Cancer, 72 (1), 191-6
DOI 10.1002/(sici)1097-0215(19970703)72:1<191::aid-ijc27>3.0.co;2-l, PubMed 9212242

Geurts van Kessel A, dos Santos NR, Simons A, de Bruijn D, Forus A, Fodstad O, Myklebost O, Balemans M, Baats E, Olde Weghuis D, Suijkerbuijk RF, van den Berg E, Molenaar WM, de Leeuw B (1997)
Molecular cytogenetics of bone and soft tissue tumors
Cancer Genet Cytogenet, 95 (1), 67-73
DOI 10.1016/s0165-4608(96)00241-5, PubMed 9140455

Maelandsmo GM, Flørenes VA, Mellingsaeter T, Hovig E, Kerbel RS, Fodstad O (1997)
Differential expression patterns of S100A2, S100A4 and S100A6 during progression of human malignant melanoma
Int J Cancer, 74 (4), 464-9
DOI 10.1002/(sici)1097-0215(19970822)74:4<464::aid-ijc19>3.0.co;2-9, PubMed 9291441

Ree AH, Florenes VA, Berg JP, Maelandsmo GM, Nesland JM, Fodstad O (1997)
High levels of messenger RNAs for tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) in primary breast carcinomas are associated with development of distant metastases
Clin Cancer Res, 3 (9), 1623-8
PubMed 9815852

Rye PD, Høifødt HK, Overli GE, Fodstad O (1997)
Immunobead filtration: a novel approach for the isolation and propagation of tumor cells
Am J Pathol, 150 (1), 99-106
PubMed 9006327

Semb KA, Fodstad O, Klem B, Bibow K, Osmundsen K, Aamdal S (1997)
Zilascorb(2H), a new reversible protein synthesis inhibitor: clinical study of an oral preparation
Anticancer Drugs, 8 (3), 296-303
DOI 10.1097/00001813-199703000-00013, PubMed 9095337

Publications 1996

Berner JM, Forus A, Elkahloun A, Meltzer PS, Fodstad O, Myklebost O (1996)
Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas
Genes Chromosomes Cancer, 17 (4), 254-9
DOI 10.1002/(SICI)1098-2264(199612)17:4<254::AID-GCC7>3.0.CO;2-2, PubMed 8946207

Bjørnland K, Buø L, Kjønniksen I, Larsen M, Fodstad O, Johansen HT, Aasen AO (1996)
Cysteine proteinase inhibitors reduce malignant melanoma cell invasion in vitro
Anticancer Res, 16 (4A), 1627-31
PubMed 8712680

Fodstad O, Breistøl K, Pettit GR, Shoemaker RH, Boyd MR (1996)
Comparative antitumor activities of halichondrins and vinblastine against human tumor xenografts
J Exp Ther Oncol, 1 (2), 119-25
PubMed 9414395

Hovig E, Fodstad O (1996)
[Prostate-specific membrane antigen]
Tidsskr Nor Laegeforen, 116 (3), 411-2
PubMed 8638273

Kvalheim G, Wang MY, Pharo A, Holte H, Jacobsen E, Beiske K, Kvaløy S, Smeland E, Funderud S, Fodstad O (1996)
Purging of tumor cells from leukapheresis products: experimental and clinical aspects
J Hematother, 5 (4), 427-36
DOI 10.1089/scd.1.1996.5.427, PubMed 8877718

Maelandsmo GM, Flørenes VA, Hovig E, Oyjord T, Engebraaten O, Holm R, Børresen AL, Fodstad O (1996)
Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas
Br J Cancer, 73 (8), 909-16
DOI 10.1038/bjc.1996.181, PubMed 8611425

Maelandsmo GM, Holm R, Fodstad O, Kerbel RS, Flørenes VA (1996)
Cyclin kinase inhibitor p21WAF1/CIP1 in malignant melanoma: reduced expression in metastatic lesions
Am J Pathol, 149 (6), 1813-22
PubMed 8952518

Maelandsmo GM, Hovig E, Skrede M, Engebraaten O, Flørenes VA, Myklebost O, Grigorian M, Lukanidin E, Scanlon KJ, Fodstad O (1996)
Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozyme
Cancer Res, 56 (23), 5490-8
PubMed 8968106

Ree AH, Maelandsmo GM, Fodstad O (1996)
Regulation of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in MCF-7 cells: comparison with regulatory mechanisms of pS2 expression
Clin Exp Metastasis, 14 (4), 381-8
DOI 10.1007/BF00123397, PubMed 8878412

Rye PD, Norum L, Olsen DR, Garman-Vik S, Kaul S, Fodstad O (1996)
Brain metastasis model in athymic nude mice using a novel MUC1-secreting human breast-cancer cell line, MA11
Int J Cancer, 68 (5), 682-7
DOI 10.1002/(SICI)1097-0215(19961127)68:5<682::AID-IJC20>3.0.CO;2-2, PubMed 8938153

Publications 1995

Deggerdal AH, Pettersen F, Kvalheim G, Hornes E, Smeland E, Fodstad O, Hovig E (1995)
Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
Lab Invest, 72 (4), 411-8
PubMed 7723279

Flørenes VA, Holm R, Fodstad O (1995)
Accumulation of p53 protein in human malignant melanoma. Relationship to clinical outcome
Melanoma Res, 5 (3), 183-7
DOI 10.1097/00008390-199506000-00007, PubMed 7640520

Forus A, Weghuis DO, Smeets D, Fodstad O, Myklebost O, Geurts van Kessel A (1995)
Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas
Genes Chromosomes Cancer, 14 (1), 15-21
DOI 10.1002/gcc.2870140104, PubMed 8527379

Forus A, Weghuis DO, Smeets D, Fodstad O, Myklebost O, van Kessel AG (1995)
Comparative genomic hybridization analysis of human sarcomas: I. Occurrence of genomic imbalances and identification of a novel major amplicon at 1q21-q22 in soft tissue sarcomas
Genes Chromosomes Cancer, 14 (1), 8-14
DOI 10.1002/gcc.2870140103, PubMed 8527390

Helseth A, Haug E, Nesland JM, Siegal GP, Fodstad O, Bautch VL (1995)
Endocrine and metabolic characteristics of polyoma large T transgenic mice that develop ACTH-producing pituitary tumors
J Neurosurg, 82 (5), 879-85
DOI 10.3171/jns.1995.82.5.0879, PubMed 7714615

Maelandsmo GM, Berner JM, Flørenes VA, Forus A, Hovig E, Fodstad O, Myklebost O (1995)
Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1
Br J Cancer, 72 (2), 393-8
DOI 10.1038/bjc.1995.344, PubMed 7640224

Rye PD, Bovin NV, Vlasova E, Høifødt HK, Kierulf B, Trones GE, Fodstad O (1995)
Breast cancer-associated antibody LU BCRU G7 recognises the terminal disaccharide Gal beta 1-3GlcNAc and can be used to isolate tumour cells from body fluids by an immunomagnetic bead procedure
Biochem Soc Trans, 23 (4), 584S
DOI 10.1042/bst023584s, PubMed 8654769

Wang MY, Fodstad O, Ludwig WD, Bengtsson M, Totterman T, Funderub S, Martin H, Kvalheim G (1995)
An Effective, Direct Immunomagnetic Procedure for Purging Acute Lymphoblastic Leukemia Cells from Human Bone Marrow
Pathol Oncol Res, 1 (1), 32-37
DOI 10.1007/BF02893581, PubMed 11173565

Wen DY, Hall WA, Conrad J, Godal A, Flørenes VA, Fodstad O (1995)
In vitro and in vivo variation in transferrin receptor expression on a human medulloblastoma cell line
Neurosurgery, 36 (6), 1158-63; discussion 1163-4
DOI 10.1227/00006123-199506000-00015, PubMed 7643997

Winderen M, Kjønniksen I, Fodstad O (1995)
Pronounced therapeutic effect of samarium 153-ethylenediaminetetramethylene phosphonate in an orthotopic human osteosarcoma tibial tumor model
J Natl Cancer Inst, 87 (3), 221-2
DOI 10.1093/jnci/87.3.221, PubMed 7707409

Publications 1994

Bruland OS, Fodstad O, Aas M, Solheim OP, Høie J, Skretting A, Winderen M, Michaelsen T, Pihl A (1994)
Immunoscintigraphy of bone sarcomas--results in 5 patients
Eur J Cancer, 30A (10), 1484-9
DOI 10.1016/0959-8049(94)00304-n, PubMed 7833107

Buø L, Bjørnland K, Karlsrud TS, Kvale D, Kjønniksen I, Fodstad O, Brandtzaeg P, Johansen HT, Aasen AO (1994)
Expression and release of plasminogen activators, their inhibitors and receptor by human tumor cell lines
Anticancer Res, 14 (6B), 2445-51
PubMed 7872665

Flørenes VA, Holm R, Myklebost O, Lendahl U, Fodstad O (1994)
Expression of the neuroectodermal intermediate filament nestin in human melanomas
Cancer Res, 54 (2), 354-6
PubMed 8275467

Flørenes VA, Maelandsmo GM, Forus A, Andreassen A, Myklebost O, Fodstad O (1994)
MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status
J Natl Cancer Inst, 86 (17), 1297-302
DOI 10.1093/jnci/86.17.1297, PubMed 8064888

Flørenes VA, Oyjord T, Holm R, Skrede M, Børresen AL, Nesland JM, Fodstad O (1994)
TP53 allele loss, mutations and expression in malignant melanoma
Br J Cancer, 69 (2), 253-9
DOI 10.1038/bjc.1994.48, PubMed 7905277

Fodstad O, Kjønniksen I (1994)
Microenvironment revisited: time for reappraisal of some prevailing concepts of cancer metastasis
J Cell Biochem, 56 (1), 23-8
DOI 10.1002/jcb.240560106, PubMed 7806588

Forus A, Flørenes VA, Maelandsmo GM, Fodstad O, Myklebost O (1994)
The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas
Cancer Genet Cytogenet, 78 (2), 165-71
DOI 10.1016/0165-4608(94)90085-x, PubMed 7828148

Hall WA, Myklebust A, Godal A, Nesland JM, Fodstad O (1994)
In vivo efficacy of intrathecal transferrin-Pseudomonas exotoxin A immunotoxin against LOX melanoma
Neurosurgery, 34 (4), 649-55; discussion 655-6
DOI 10.1227/00006123-199404000-00012, PubMed 8008162

Kashani-Sabet M, Funato T, Florenes VA, Fodstad O, Scanlon KJ (1994)
Suppression of the neoplastic phenotype in vivo by an anti-ras ribozyme
Cancer Res, 54 (4), 900-2
PubMed 8313379

Kjønniksen I, Rye PD, Fodstad O (1994)
Helix pomatia agglutinin binding in human tumour cell lines: correlation with pulmonary metastases in nude mice
Br J Cancer, 69 (6), 1021-4
DOI 10.1038/bjc.1994.200, PubMed 8198963

Kjønniksen I, Winderen M, Bruland O, Fodstad O (1994)
Validity and usefulness of human tumor models established by intratibial cell inoculation in nude rats
Cancer Res, 54 (7), 1715-9
PubMed 8137286

Kvalheim G, Jakobsen E, Holte H, Beiske K, Langholm R, Høiby A, Wang MY, Funderund S, Fodstad O, Smeland E (1994)
Autologous bone marrow transplantation of non-Hodgkin's lymphoma patients with marrow purged using immunomagnetic beads
Prog Clin Biol Res, 389, 133-8
PubMed 7700895

Langdon SP, Hendriks HR, Braakhuis BJ, Pratesi G, Berger DP, Fodstad O, Fiebig HH, Boven E (1994)
Preclinical phase II studies in human tumor xenografts: a European multicenter follow-up study
Ann Oncol, 5 (5), 415-22
DOI 10.1093/oxfordjournals.annonc.a058872, PubMed 8075048

Myklebust AT, Godal A, Fodstad O (1994)
Targeted therapy with immunotoxins in a nude rat model for leptomeningeal growth of human small cell lung cancer
Cancer Res, 54 (8), 2146-50
PubMed 8174121

Myklebust AT, Godal A, Juell S, Pharo A, Fodstad O (1994)
Comparison of two antibody-based methods for elimination of breast cancer cells from human bone marrow
Cancer Res, 54 (1), 209-14
PubMed 7505198

Myklebust AT, Helseth A, Breistøl K, Hall WA, Fodstad O (1994)
Nude rat models for human tumor metastasis to CNS. Procedures for intracarotid delivery of cancer cells and drugs
J Neurooncol, 21 (3), 215-24
DOI 10.1007/BF01063770, PubMed 7699416

Wang MY, Fodstad O, Funderud S, Bengtsson M, Totterman T, Ludwig WD, Martin H, Kvalheim G (1994)
A direct and effective immunomagnetic method for bone marrow purging in non-T ALL malignancies. The use of an anti-HLA-DR antibody gives sustained engraftment
Prog Clin Biol Res, 389, 119-24
PubMed 7700893

Publications 1993


FODSTAD O (1993)

Forus A, Flørenes VA, Maelandsmo GM, Meltzer PS, Fodstad O, Myklebost O (1993)
Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2
Cell Growth Differ, 4 (12), 1065-70
PubMed 8117620

Helseth A, Bautch VL, Haug E, Holm R, Nesland JM, Fodstad O (1993)
[Transgenic mice as animal model of Cushing's syndrome]
Tidsskr Nor Laegeforen, 113 (2), 206-10
PubMed 8381565

Myklebust AT, Godal A, Pharo A, Juell S, Fodstad O (1993)
Eradication of small cell lung cancer cells from human bone marrow with immunotoxins
Cancer Res, 53 (16), 3784-8
PubMed 8393381

Myklebust AT, Pharo A, Fodstad O (1993)
Effective removal of SCLC cells from human bone marrow. Use of four monoclonal antibodies and immunomagnetic beads
Br J Cancer, 67 (6), 1331-6
DOI 10.1038/bjc.1993.246, PubMed 8390285

Schmid U, Bailly M, Fodstad O, Bihl H, Matzku S (1993)
Monoclonal antibody accumulation in experimental and spontaneous lung metastases of human malignant melanoma in rodents
J Cancer Res Clin Oncol, 119 (6), 342-5
DOI 10.1007/BF01208842, PubMed 8449971

Wen DY, Hall WA, Fodstad O (1993)
Rapid detection of transferrin receptor expression on glioma cell lines by using magnetic microspheres
Neurosurgery, 33 (5), 878-81
DOI 10.1227/00006123-199311000-00015, PubMed 8264887

Publications 1992

Beiske K, Myklebust AT, Aamdal S, Langholm R, Jakobsen E, Fodstad O (1992)
Detection of bone marrow metastases in small cell lung cancer patients. Comparison of immunologic and morphologic methods
Am J Pathol, 141 (3), 531-8
PubMed 1381558

Boven E, Winograd B, Berger DP, Dumont MP, Braakhuis BJ, Fodstad O, Langdon S, Fiebig HH (1992)
Phase II preclinical drug screening in human tumor xenografts: a first European multicenter collaborative study
Cancer Res, 52 (21), 5940-7
PubMed 1394220

Flørenes VA, Aamdal S, Myklebost O, Maelandsmo GM, Bruland OS, Fodstad O (1992)
Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression
Cancer Res, 52 (21), 6088-91
PubMed 1356624

Godal A, Kumle B, Pihl A, Juell S, Fodstad O (1992)
Immunotoxins directed against the high-molecular-weight melanoma-associated antigen. Identification of potent antibody-toxin combinations
Int J Cancer, 52 (4), 631-5
DOI 10.1002/ijc.2910520423, PubMed 1399146

Hall WA, Fodstad O (1992)
Immunotoxins and central nervous system neoplasia
J Neurosurg, 76 (1), 1-12
DOI 10.3171/jns.1992.76.1.0001, PubMed 1727147

Hall WA, Godal A, Juell S, Fodstad O (1992)
In vitro efficacy of transferrin-toxin conjugates against glioblastoma multiforme
J Neurosurg, 76 (5), 838-44
DOI 10.3171/jns.1992.76.5.0838, PubMed 1314294

Hendriks HR, Langdon S, Berger DP, Breistøl K, Fiebig HH, Fodstad O, Schwartsmann G (1992)
Comparative antitumour activity of vinblastine-isoleucinate and related vinca alkaloids in human tumour xenografts
Eur J Cancer, 28A (4-5), 767-73
DOI 10.1016/0959-8049(92)90112-f, PubMed 1524896

Hendriks HR, Plowman J, Berger DP, Paull KD, Fiebig HH, Fodstad O, Dreef-van der Meulen HC, Henrar RE, Pinedo HM, Schwartsmann G (1992)
Preclinical antitumour activity and animal toxicology studies of rhizoxin, a novel tubulin-interacting agent
Ann Oncol, 3 (9), 755-63
DOI 10.1093/oxfordjournals.annonc.a058334, PubMed 1450065

Kjønniksen I, Breistøl K, Fodstad O (1992)
Site-dependent differences in sensitivity of LOX human melanoma tumors in nude rats to dacarbazine and mitozolomide, but not to doxorubicin and cisplatin
Cancer Res, 52 (5), 1347-51
PubMed 1737396

Eur. J. Med. Chem., 27 (8), 825-833
DOI 10.1016/0223-5234(92)90117-J

Wang MY, Kvalheim G, Kvaløy S, Beiske K, Jakobsen E, Wijdenes J, Pihl A, Fodstad O (1992)
An effective immunomagnetic method for bone marrow purging in T cell malignancies
Bone Marrow Transplant, 9 (5), 319-23
PubMed 1617315

Publications 1991

Fodstad O (1991)
Tumorigenicity and dissemination of human tumors in congenitally immune-deficient mice
J Natl Cancer Inst, 83 (19), 1419-20
DOI 10.1093/jnci/83.19.1419, PubMed 1920486

Hovig E, Lothe R, Farrants G, Brøgger A, Fodstad O, Børresen AL (1991)
Chromosome 13 alterations in osteosarcoma cell lines derived from a patient with previous retinoblastoma
Cancer Genet Cytogenet, 57 (1), 31-40
DOI 10.1016/0165-4608(91)90186-x, PubMed 1684533

Kjønniksen I, Høifødt HK, Pihl A, Fodstad O (1991)
Different metastasis patterns of a human melanoma cell line in nude mice and rats: influence of microenvironment
J Natl Cancer Inst, 83 (14), 1020-4
DOI 10.1093/jnci/83.14.1020, PubMed 2072409

Myklebust AT, Beiske K, Pharo A, Davies CD, Aamdal S, Fodstad O (1991)
Selection of anti-SCLC antibodies for diagnosis of bone marrow metastasis
Br J Cancer Suppl, 14, 49-53
PubMed 1645572

Br. J. Cancer, 63 14, 49-53

Shoemaker RH, Dykes DJ, Plowman J, Harrison SD, Griswold DP, Abbott BJ, Mayo JG, Fodstad O, Boyd MR (1991)
Practical spontaneous metastasis model for in vivo therapeutic studies using a human melanoma
Cancer Res, 51 (11), 2837-41
PubMed 2032224

Storeng RT, Kjønniksen I, Pihl A, Haug E, Fodstad O (1991)
Athymic rats in preclinical immunodiagnostic studies
Anticancer Res, 11 (2), 649-55
PubMed 2064318

Publications 1990

J. Natl. Cancer Inst., 82 (12), 1070
DOI 10.1093/jnci/82.12.1070

Kjønniksen I, Nesland JM, Pihl A, Fodstad O (1990)
Nude rat model for studying metastasis of human tumor cells to bone and bone marrow
J Natl Cancer Inst, 82 (5), 408-12
DOI 10.1093/jnci/82.5.408, PubMed 2304088

Publications 1989

Kjønniksen I, Storeng R, Pihl A, McLemore TL, Fodstad O (1989)
A human tumor lung metastasis model in athymic nude rats
Cancer Res, 49 (18), 5148-52
PubMed 2766284

Kvalheim G, Fjeld JG, Pihl A, Funderud S, Ugelstad J, Fodstad O, Nustad K (1989)
Immunomagnetic removal of B-lymphoma cells using a novel mono-sized magnetizable polymer bead, M-280, in conjunction with primary IgM and IgG antibodies
Bone Marrow Transplant, 4 (5), 567-74
PubMed 2790334

Shew JY, Ling N, Yang XM, Fodstad O, Lee WH (1989)
Antibodies detecting abnormalities of the retinoblastoma susceptibility gene product (pp110RB) in osteosarcomas and synovial sarcomas
Oncogene Res, 4 (3), 205-14
PubMed 2740144

Publications 1988

Boven E, Winograd B, Fodstad O, Lobbezoo MW, Pinedo HM (1988)
Preclinical phase II studies in human tumor lines: a European multicenter study
Eur J Cancer Clin Oncol, 24 (3), 567-73
DOI 10.1016/s0277-5379(98)90039-6, PubMed 3383962

Bruland OS, Fodstad O, Stenwig AE, Pihl A (1988)
Expression and characteristics of a novel human osteosarcoma-associated cell surface antigen
Cancer Res, 48 (18), 5302-9
PubMed 2457439

Fodstad O, Kjønniksen I, Aamdal S, Nesland JM, Boyd MR, Pihl A (1988)
Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
Cancer Res, 48 (15), 4382-8
PubMed 3390834

Fodstad O, Kvalheim G, Pihl A, Godal A, Funderud S (1988)
New indirect approach to the therapeutic use of immunotoxins
J Natl Cancer Inst, 80 (6), 439-43
DOI 10.1093/jnci/80.6.439, PubMed 3259265

Fodstad O, Aamdal S, McMenamin M, Nesland JM, Pihl A (1988)
A new experimental metastasis model in athymic nude mice, the human malignant melanoma LOX
Int J Cancer, 41 (3), 442-9
DOI 10.1002/ijc.2910410322, PubMed 3346110

Godal A, Fodstad O, Pihl A (1988)
Kinetics of uptake and degradation of an abrin immunotoxin by melanoma cells and studies of the rates of cellular intoxication
Int J Cancer, 42 (3), 400-4
DOI 10.1002/ijc.2910420316, PubMed 3262091

Bone Marrow Transplant., 3 1, 97

Kvalheim G, Funderud S, Kvaløy S, Gaudernack G, Beiske K, Jakobsen E, Jacobsen AB, Pihl A, Fodstad O (1988)
Successful clinical use of an anti-HLA-DR monoclonal antibody for autologous bone marrow transplantation
J Natl Cancer Inst, 80 (16), 1322-5
DOI 10.1093/jnci/80.16.1322, PubMed 3050139

Kvalheim G, Sørensen O, Fodstad O, Funderud S, Kiesel S, Dörken B, Nustad K, Jakobsen E, Ugelstad J, Pihl A (1988)
Immunomagnetic removal of B-lymphoma cells from human bone marrow: a procedure for clinical use
Bone Marrow Transplant, 3 (1), 31-41
PubMed 3048468

Aamdal S, Fodstad O, Pihl A (1988)
Sodium thiosulfate fails to increase the therapeutic index of intravenously administered cis-diamminedichloroplatinum (II) in mice bearing murine and human tumors
Cancer Chemother Pharmacol, 21 (2), 129-33
DOI 10.1007/BF00257358, PubMed 3349560

Publications 1987

Bruland O, Fodstad O, Skretting A, Pihl A (1987)
Selective localisation of two radiolabelled anti-sarcoma monoclonal antibodies in human osteosarcoma xenografts
Br J Cancer, 56 (1), 21-5
DOI 10.1038/bjc.1987.146, PubMed 3476143

Fine DL, Shoemaker R, Gazdar A, Mayo JG, Fodstad O, Boyd MR, Abbott BJ, Donovan PA (1987)
Metastasis models for human tumors in athymic mice: useful models for drug development
Cancer Detect Prev Suppl, 1, 291-9
PubMed 3480056

Godal A, Fodstad O, Pihl A (1987)
Studies on the mechanism of action of abrin-9.2.27 immunotoxin in human melanoma cell lines
Cancer Res, 47 (23), 6243-7
PubMed 2445469

Gundersen S, Aamdal S, Fodstad O (1987)
Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
Br J Cancer, 55 (4), 433-5
DOI 10.1038/bjc.1987.85, PubMed 3580266

Hovig E, Winberg JO, Fodstad O, Brøgger A, Gedde-Dahl T (1987)
Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
Cancer Genet Cytogenet, 24 (2), 327-34
DOI 10.1016/0165-4608(87)90115-4, PubMed 2878716

Kvalheim G, Fodstad O, Pihl A, Nustad K, Pharo A, Ugelstad J, Funderud S (1987)
Elimination of B-lymphoma cells from human bone marrow: model experiments using monodisperse magnetic particles coated with primary monoclonal antibodies
Cancer Res, 47 (3), 846-51
PubMed 3492268

Aamdal S, Fodstad O, Pihl A (1987)
Some procedures to reduce cis-platinum toxicity reduce antitumour activity
Cancer Treat Rev, 14 (3-4), 389-95
DOI 10.1016/0305-7372(87)90035-1, PubMed 3326670

Publications 1986

Bruland O, Fodstad O, Funderud S, Pihl A (1986)
New monoclonal antibodies specific for human sarcomas
Int J Cancer, 38 (1), 27-31
DOI 10.1002/ijc.2910380106, PubMed 3522438

Fodstad O, Brøgger A, Bruland O, Solheim OP, Nesland JM, Pihl A (1986)
Characteristics of a cell line established from a patient with multiple osteosarcoma, appearing 13 years after treatment for bilateral retinoblastoma
Int J Cancer, 38 (1), 33-40
DOI 10.1002/ijc.2910380107, PubMed 3459716

Godal A, Bruland O, Haug E, Aas M, Fodstad O (1986)
Unexpected expression of the 250 kD melanoma-associated antigen in human sarcoma cells
Br J Cancer, 53 (6), 839-41
DOI 10.1038/bjc.1986.142, PubMed 3718838

Godal A, Fodstad O, Morgan AC, Pihl A (1986)
Human melanoma cell lines showing striking inherent differences in sensitivity to immunotoxins containing holotoxins
J Natl Cancer Inst, 77 (6), 1247-53
PubMed 3491924

Aamdal S, Fodstad O, Kaalhus O, Pihl A (1986)
Chemosensitivity profiles of human cancers assessed by the 6-day SRC assay on serially xenografted tumors
Int J Cancer, 37 (4), 579-87
DOI 10.1002/ijc.2910370417, PubMed 3957463

Publications 1985

Bruland O, Fodstad O, Pihl A (1985)
The use of multicellular spheroids in establishing human sarcoma cell lines in vitro
Int J Cancer, 35 (6), 793-8
DOI 10.1002/ijc.2910350616, PubMed 2409034

Fodstad O, Aamdal S, Pihl A, Boyd MR (1985)
Activity of mitozolomide (NSC 353451), a new imidazotetrazine, against xenografts from human melanomas, sarcomas, and lung and colon carcinomas
Cancer Res, 45 (4), 1778-86
PubMed 3978640

Hansen MF, Koufos A, Gallie BL, Phillips RA, Fodstad O, Brøgger A, Gedde-Dahl T, Cavenee WK (1985)
Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition
Proc Natl Acad Sci U S A, 82 (18), 6216-20
DOI 10.1073/pnas.82.18.6216, PubMed 2994066

Hwang KM, Fodstad O, Oldham RK, Morgan AC (1985)
Radiolocalization of xenografted human malignant melanoma by a monoclonal antibody (9.2.27) to a melanoma-associated antigen in nude mice
Cancer Res, 45 (9), 4150-5
PubMed 4028007

Kvalheim G, Gundersen S, Hager B, Fodstad O (1985)
Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients
Radiother Oncol, 4 (2), 127-32
DOI 10.1016/s0167-8140(85)80099-2, PubMed 3934716

Aamdal S, Fodstad O, Nesland JM, Pihl A (1985)
Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
Br J Cancer, 51 (3), 347-56
DOI 10.1038/bjc.1985.46, PubMed 3970811

Aamdal S, Fodstad O, Pihl A (1985)
The six-day subrenal capsule assay (SRCA) for testing the response of human tumours to anticancer agents. Validity and usefulness in cancer research and treatment
Ann Chir Gynaecol Suppl, 199, 51-9
PubMed 3864392

Aamdal S, Fodstad O, Pihl A (1985)
Methodological aspects of the 6-day subrenal capsule assay for measuring the response of human tumors to anticancer agents
Anticancer Res, 5 (4), 329-37
PubMed 4037730

Ann. Chir. Gynaecol., 74 199, 51-59

Publications 1984

Fodstad O, Hansen CT, Cannon GB, Boyd MR (1984)
Immune characteristics of the beige-nude mouse. A model for studying immune surveillance
Scand J Immunol, 20 (3), 267-72
DOI 10.1111/j.1365-3083.1984.tb01002.x, PubMed 6494809

Fodstad O, Hansen CT, Cannon GB, Statham CN, Lichtenstein GR, Boyd MR (1984)
Lack of correlation between natural killer activity and tumor growth control in nude mice with different immune defects
Cancer Res, 44 (10), 4403-8
PubMed 6467201

Fodstad O, Kvalheim G, Godal A, Lotsberg J, Aamdal S, Høst H, Pihl A (1984)
Phase I study of the plant protein ricin
Cancer Res, 44 (2), 862-5
PubMed 6692385

Godal A, Fodstad O, Ingebrigtsen K, Pihl A (1984)
Pharmacological studies of ricin in mice and humans
Cancer Chemother Pharmacol, 13 (3), 157-63
DOI 10.1007/BF00269021, PubMed 6488437

Lindmo T, Davies C, Fodstad O, Morgan AC (1984)
Stable quantitative differences of antigen expression in human melanoma cells isolated by flow cytometric cell sorting
Int J Cancer, 34 (4), 507-12
DOI 10.1002/ijc.2910340413, PubMed 6386700

Lindmo T, Davies C, Rofstad EK, Fodstad O, Sundan A (1984)
Antigen expression in human melanoma cells in relation to growth conditions and cell-cycle distribution
Int J Cancer, 33 (2), 167-71
DOI 10.1002/ijc.2910330203, PubMed 6693198

Nesland JM, Kjellevold K, Finseth I, Fodstad O (1984)
Spherical bodies
Ultrastruct Pathol, 7 (1), 73-8
DOI 10.3109/01913128409141857, PubMed 6097001

Aamdal S, Fodstad O, Kaalhus O, Pihl A (1984)
Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
J Natl Cancer Inst, 73 (3), 743-52
PubMed 6590919

Aamdal S, Fodstad O, Pihl A (1984)
Human tumor xenografts transplanted under the renal capsule of conventional mice. Growth rates and host immune response
Int J Cancer, 34 (5), 725-30
DOI 10.1002/ijc.2910340521, PubMed 6500747

Publications 1983

Fodstad O, Rofstad EK, Tveit KM, Pihl A (1983)
Spontaneous alteration in growth rates of two human melanoma xenografts. Concurrent changes in chemosensitivity
Eur J Cancer Clin Oncol, 19 (8), 1175-8
DOI 10.1016/0277-5379(83)90046-9, PubMed 6684563

Godal A, Fodstad O, Pihl A (1983)
Antibody formation against the cytotoxic proteins abrin and ricin in humans and mice
Int J Cancer, 32 (4), 515-21
DOI 10.1002/ijc.2910320420, PubMed 6618711

Publications 1982

Fodstad O, Pihl A (1982)
Synergistic effect of ricin in combination with daunorubicin, cis-dichlorodiammineplatinum(II) and vincristine in systemic L1210 leukemia
Cancer Res, 42 (6), 2152-8
PubMed 7200398

Rofstad EK, Fodstad O, Lindmo T (1982)
Growth characteristics of human melanoma xenografts
Cell Tissue Kinet, 15 (5), 545-54
DOI 10.1111/j.1365-2184.1982.tb01576.x, PubMed 7127402

Tveit KM, Fodstad O, Lotsberg J, Vaage S, Pihl A (1982)
Colony growth and chemosensitivity in vitro of human melanoma biopsies. Relationship to clinical parameters
Int J Cancer, 29 (5), 533-8
DOI 10.1002/ijc.2910290508, PubMed 7095899

Publications 1981

Tveit KM, Endresen L, Rugstad HE, Fodstad O, Pihl A (1981)
Comparison of two soft-agar methods for assaying chemosensitivity of human tumours in vitro: malignant melanomas
Br J Cancer, 44 (4), 539-44
DOI 10.1038/bjc.1981.223, PubMed 7295510

Tveit KM, Fodstad O, Pihl A (1981)
The usefulness of human tumor cell lines in the study of chemosensitivity. A study of malignant melanomas
Int J Cancer, 28 (4), 403-8
DOI 10.1002/ijc.2910280402, PubMed 7309286

Tveit KM, Fodstad O, Pihl A (1981)
Cultivation of human melanomas in soft agar. Factors influencing plating efficiency and chemosensitivity
Int J Cancer, 28 (3), 329-34
DOI 10.1002/ijc.2910280312, PubMed 7319675

Publications 1980

Fodstad O, Pihl A (1980)
Synergistic effect of adriamycin and ricin on L1210 leukemic cells in mice
Cancer Res, 40 (10), 3735-9
PubMed 7438056

Fodstad O, Pihl A (1980)
Doxorubicin and ricin, a strongly synergistic combination in mouse leukemia
Cancer Treat Rep, 64 (12), 1375-8
PubMed 7471125

Fodstad O, Aass N, Pihl A (1980)
Assessment of tumour growth and of response to chemotherapy of human melanomas in athymic, nude mice
Br J Cancer Suppl, 4, 146-9
PubMed 6932918

Fodstad O, Aass N, Pihl A (1980)
Response to chemotherapy of human, malignant melanoma xenografts in athymic, nude mice
Int J Cancer, 25 (4), 453-8
DOI 10.1002/ijc.2910250405, PubMed 7372371

Fodstad O, Aass N, Pihl A (1980)
An inverse relationship between the growth rate of human melanoma xenografts and their response to some cytostatic drugs
Br J Cancer, 41 (5), 829-31
DOI 10.1038/bjc.1980.149, PubMed 7426308

Br. J. Cancer, 41 4, 146-149

Fodstad Ø (1980)
Preclinical studies of the cancerostatic lectins abrin and ricin: toxicity and effect on murine tumors and on human tumor xenografts in athymic, nude mice
[Forfatteren], Oslo, 1 b. (fl.pag.)
BIBSYS 812138147

Tveit KM, Fodstad O, Brøgger A, Olsnes S (1980)
Human embryonal carcinoma grown in athymic mice and in vitro
Cancer Res, 40 (3), 949-53
PubMed 7471109

Tveit KM, Fodstad O, Johannessen JV, Olsnes S (1980)
A human melanoma cell line established from xenograft in athymic mice
Br J Cancer, 41 (5), 724-33
DOI 10.1038/bjc.1980.134, PubMed 7426299

Tveit KM, Fodstad O, Olsnes S, Pihl A (1980)
In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity
Int J Cancer, 26 (6), 717-22
DOI 10.1002/ijc.2910260604, PubMed 7216540

Publications 1979

Fodstad O (1979)
Human gastrointestinal cancer grown in nude mice used to test new chemotherapeutic agents
Front Gastrointest Res, 5, 71-80
DOI 10.1159/000402313, PubMed 91567

Fodstad O, Johannessen JV, Schjerven L, Pihl A (1979)
Toxicity of abrin and ricin in mice and dogs
J Toxicol Environ Health, 5 (6), 1073-84
DOI 10.1080/15287397909529815, PubMed 529341

Gundersen S, Fodstad O (1979)
Treatment of micrometastases from Lewis lung carcinoma with abrin and cyclophosphamide, given singly and in combination
Int J Cancer, 23 (4), 530-5
DOI 10.1002/ijc.2910230414, PubMed 437927

Publications 1978

Fodstad O, Pihl A (1978)
Effect of ricin and abrin on survival of L1210 leukemic mice and on leukemic and normal bone-marrow cells
Int J Cancer, 22 (5), 558-63
DOI 10.1002/ijc.2910220509, PubMed 721316

Publications 1977

Fodstad O, Olsnes S (1977)
Studies on the accessability of ribosomes to inactivation by the toxic lectins abrin and ricin
Eur J Biochem, 74 (2), 209-15
DOI 10.1111/j.1432-1033.1977.tb11383.x, PubMed 856578

Fodstad O, Olsnes S, Pihl A (1977)
Inhibitory effect of abrin and ricin on the growth of transplantable murine tumors and of abrin on human cancers in nude mice
Cancer Res, 37 (12), 4559-67
PubMed 922739

Publications 1976

Fodstad O, Olsnes S, Pihl A (1976)
Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice
Br J Cancer, 34 (4), 418-25
DOI 10.1038/bjc.1976.187, PubMed 974006

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