OUH - Metabolomics and Metabolic Molecular Biology

Anja Østeby Vassli

Spesialingeniør; MSc

Status: On maternity leave until March 2024

Education

2013: MSc in Analytical Chemistry, University of Oslo, Norway
2008: BSc in Engineering (Biotechnology and Chemistry), Oslo Metropolitan University, Norway

Affiliation

Metabolomics & Metabolic Molecular Biology Group, Department of Medical Biochemistry, Oslo University Hospital - Rikshospitalet, Norway

Research Summary

Anja's main research interest is metabolomics using liquid-chromatography combined with high-resolution mass spectrometry analysis. This holistic approach is suited for gaining understanding of unknown biochemical mechanisms and biomarker discovery in different biofluids.

Highlights:

A new method paper, adding valuable information to the field of Clinical Metabolomics: Skogvold et al. (2021)
A novel metabolomics study of human 3-NPA intoxication, reporting the 1st case in Norway and the 2nd in Scandinavia: Skogvold et al. (2021)
Under the Most Downloaded Articles (All Time) of the journal: Skogvold et al. (2021)

Work Experience

2013 – to date: Chemist at the Department of Medical Biochemistry, Oslo University Hospital, Norway

Links

NB: Check out our NEWS PAGE for the latest!

Publications 2023

Hiller JK, Sandås EM, Rootwelt H, Østeby Vassli A, Utheim TP, Moe MC, Elgstøen KBP, Petrovski G (2023)
Ex Vivo Pig Eye Model for Studying Diffusion of Acylcarnitines with Different Physicochemical Properties
J Ocul Pharmacol Ther, 39 (5), 324-331
DOI 10.1089/jop.2022.0159, PubMed 37219540

Salvador CL, Oppebøen M, Vassli AØ, Pfeiffer HCV, Varhaug KN, Elgstøen KBP, Yazdani M (2023)
Increased Sphingomyelin and Free Sialic Acid in Cerebrospinal Fluid of Kearns-Sayre Syndrome: New Findings Using Untargeted Metabolomics
Pediatr Neurol, 143, 68-76
DOI 10.1016/j.pediatrneurol.2023.02.016, PubMed 37018879

Publications 2022

Böhm HO, Yazdani M, Sandås EM, Østeby Vassli A, Kristensen E, Rootwelt H, Skogvold HB, Brodtkorb E, Elgstøen KBP (2022)
Global Metabolomics Discovers Two Novel Biomarkers in Pyridoxine-Dependent Epilepsy Caused by ALDH7A1 Deficiency
Int J Mol Sci, 23 (24)
DOI 10.3390/ijms232416061, PubMed 36555701

Publications 2021

Bendiksen Skogvold H, Yazdani M, Sandås EM, Østeby Vassli A, Kristensen E, Haarr D, Rootwelt H, Elgstøen KBP (2021)
A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics
J Appl Toxicol, 42 (5), 818-829
DOI 10.1002/jat.4259, PubMed 34725838

Skogvold HB, Sandås EM, Østeby A, Løkken C, Rootwelt H, Rønning PO, Wilson SR, Elgstøen KBP (2021)
Bridging the Polar and Hydrophobic Metabolome in Single-Run Untargeted Liquid Chromatography-Mass Spectrometry Dried Blood Spot Metabolomics for Clinical Purposes
J Proteome Res, 20 (8), 4010-4021
DOI 10.1021/acs.jproteome.1c00326, PubMed 34296888

Zawadzka M, Ràcz B, Ambrosini D, Görbitz CH, Morth JP, Wilkins AL, Østeby A, Elgstøen KBP, Lundanes E, Rise F, Ringvold A, Wilson SR (2021)
Searching for a UV-filter in the eyes of high-flying birds
Sci Rep, 11 (1), 273
DOI 10.1038/s41598-020-79533-2, PubMed 33431985