Vidar Gundersen

  • Professor, Consulant Neurologist; MD, PhD

Original articles

Nordengen K, Morland C, Slusher BS, Gundersen V (2019)
Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus
Cereb Cortex (in press)
DOI 10.1093/cercor/bhz176, PubMed 31504271

Petrelli F, Dallérac G, Pucci L, Calì C, Zehnder T, Sultan S, Lecca S, Chicca A, Ivanov A, Asensio CS, Gundersen V, Toni N, Knott GW, Magara F, Gertsch J, Kirchhoff F, Déglon N, Giros B, Edwards RH, Mothet JP, Bezzi P (2018)
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments
Mol Psychiatry (in press)
DOI 10.1038/s41380-018-0226-y, PubMed 30127471

Morland C, Frøland AS, Pettersen MN, Storm-Mathisen J, Gundersen V, Rise F, Hassel B (2018)
Propionate enters GABAergic neurons, inhibits GABA transaminase, causes GABA accumulation and lethargy in a model of propionic acidemia
Biochem J, 475 (4), 749-758
DOI 10.1042/BCJ20170814, PubMed 29339464

Prydz A, Stahl K, Puchades M, Davarpaneh N, Nadeem M, Ottersen OP, Gundersen V, Amiry-Moghaddam M (2017)
Subcellular expression of aquaporin-4 in substantia nigra of normal and MPTP-treated mice
Neuroscience, 359, 258-266
DOI 10.1016/j.neuroscience.2017.07.029, PubMed 28735099

Gundersen V, Stange EE, Kaltenborn BP, Vistad OI (2017)
Public visual preferences for dead wood in natural boreal forests: The effects of added information
Landsc. Urban Plan., 158, 12-24

Gundersen V, Skar M, O'Brien L, Wold LC, Follo G (2016)
Children and nearby nature: A nationwide parental survey from Norway
Urban For. Urban Green., 17, 116-125

Stensrud MJ, Sogn CJ, Gundersen V (2015)
Immunogold characteristics of VGLUT3-positive GABAergic nerve terminals suggest corelease of glutamate
J Comp Neurol, 523 (18), 2698-713
DOI 10.1002/cne.23811, PubMed 26010578

Nordengen K, Heuser C, Rinholm JE, Matalon R, Gundersen V (2013)
Localisation of N-acetylaspartate in oligodendrocytes/myelin
Brain Struct Funct, 220 (2), 899-917
DOI 10.1007/s00429-013-0691-7, PubMed 24379086

Nagelhus EA, Amiry-Moghaddam M, Bergersen LH, Bjaalie JG, Eriksson J, Gundersen V, Leergaard TB, Morth JP, Storm-Mathisen J, Torp R, Walhovd KB, Tønjum T (2013)
The glia doctrine: addressing the role of glial cells in healthy brain ageing
Mech Ageing Dev, 134 (10), 449-59
DOI 10.1016/j.mad.2013.10.001, PubMed 24141107

Stensrud MJ, Chaudhry FA, Leergaard TB, Bjaalie JG, Gundersen V (2013)
Vesicular glutamate transporter-3 in the rodent brain: vesicular colocalization with vesicular γ-aminobutyric acid transporter
J Comp Neurol, 521 (13), 3042-56
DOI 10.1002/cne.23331, PubMed 23633129

Stensrud MJ, Puchades M, Gundersen V (2013)
GABA is localized in dopaminergic synaptic vesicles in the rodent striatum
Brain Struct Funct, 219 (6), 1901-12
DOI 10.1007/s00429-013-0609-4, PubMed 23851655

Ersland KM, Håvik B, Rinholm JE, Gundersen V, Stansberg C, Steen VM (2013)
LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex
BMC Neurosci, 14, 68
DOI 10.1186/1471-2202-14-68, PubMed 23844656

Sogn CJ, Puchades M, Gundersen V (2013)
Rare contacts between synapses and microglial processes containing high levels of Iba1 and actin--a postembedding immunogold study in the healthy rat brain
Eur J Neurosci, 38 (1), 2030-40
DOI 10.1111/ejn.12213, PubMed 23590220

Puchades M, Sogn CJ, Maehlen J, Bergersen LH, Gundersen V (2013)
Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease
J Parkinsons Dis, 3 (3), 371-85
DOI 10.3233/JPD-130190, PubMed 23963315

Morland C, Nordengen K, Larsson M, Prolo LM, Farzampour Z, Reimer RJ, Gundersen V (2012)
Vesicular uptake and exocytosis of L-aspartate is independent of sialin
FASEB J, 27 (3), 1264-74
DOI 10.1096/fj.12-206300, PubMed 23221336

Berg LK, Larsson M, Morland C, Gundersen V (2012)
Pre- and postsynaptic localization of NMDA receptor subunits at hippocampal mossy fibre synapses
Neuroscience, 230, 139-50
DOI 10.1016/j.neuroscience.2012.10.061, PubMed 23159309

Morland C, Nordengen K, Gundersen V (2012)
Valproate causes reduction of the excitatory amino acid aspartate in nerve terminals
Neurosci Lett, 527 (2), 100-4
DOI 10.1016/j.neulet.2012.08.042, PubMed 22963924

Ormel L, Stensrud MJ, Chaudhry FA, Gundersen V (2012)
A distinct set of synaptic-like microvesicles in atroglial cells contain VGLUT3
Glia, 60 (9), 1289-300
DOI 10.1002/glia.22348, PubMed 22573606

Ormel L, Stensrud MJ, Bergersen LH, Gundersen V (2011)
VGLUT1 is localized in astrocytic processes in several brain regions
Glia, 60 (2), 229-38
DOI 10.1002/glia.21258, PubMed 22009457

Bergersen LH, Morland C, Ormel L, Rinholm JE, Larsson M, Wold JF, Røe AT, Stranna A, Santello M, Bouvier D, Ottersen OP, Volterra A, Gundersen V (2011)
Immunogold detection of L-glutamate and D-serine in small synaptic-like microvesicles in adult hippocampal astrocytes
Cereb Cortex, 22 (7), 1690-7
DOI 10.1093/cercor/bhr254, PubMed 21914633

Larsson M, Sawada K, Morland C, Hiasa M, Ormel L, Moriyama Y, Gundersen V (2011)
Functional and anatomical identification of a vesicular transporter mediating neuronal ATP release
Cereb Cortex, 22 (5), 1203-14
DOI 10.1093/cercor/bhr203, PubMed 21810784

Toft M, Lilleeng B, Ramm-Pettersen J, Skogseid IM, Gundersen V, Gerdts R, Pedersen L, Skjelland M, Røste GK, Dietrichs E (2011)
Long-term efficacy and mortality in Parkinson's disease patients treated with subthalamic stimulation
Mov Disord, 26 (10), 1931-4
DOI 10.1002/mds.23817, PubMed 21656853

Larsson M, Morland C, Poblete-Naredo I, Biber J, Danbolt NC, Gundersen V (2011)
The sodium-dependent inorganic phosphate transporter SLC34A1 (NaPi-IIa) is not localized in the mouse brain: a case of tissue-specific antigenic cross-reactivity
J Histochem Cytochem, 59 (9), 807-12
DOI 10.1369/0022155411411713, PubMed 21606201

Gammelsaeter R, Coppola T, Marcaggi P, Storm-Mathisen J, Chaudhry FA, Attwell D, Regazzi R, Gundersen V (2011)
A role for glutamate transporters in the regulation of insulin secretion
PLoS One, 6 (8), e22960
DOI 10.1371/journal.pone.0022960, PubMed 21853059

Gammelsaeter R, Jenstad M, Bredahl MK, Gundersen V, Chaudhry FA (2009)
Complementary expression of SN1 and SAT2 in the islets of Langerhans suggests concerted action of glutamine transport in the regulation of insulin secretion
Biochem Biophys Res Commun, 381 (3), 378-82
DOI 10.1016/j.bbrc.2009.02.062, PubMed 19233140

Furness DN, Dehnes Y, Akhtar AQ, Rossi DJ, Hamann M, Grutle NJ, Gundersen V, Holmseth S, Lehre KP, Ullensvang K, Wojewodzic M, Zhou Y, Attwell D, Danbolt NC (2008)
A quantitative assessment of glutamate uptake into hippocampal synaptic terminals and astrocytes: new insights into a neuronal role for excitatory amino acid transporter 2 (EAAT2)
Neuroscience, 157 (1), 80-94
DOI 10.1016/j.neuroscience.2008.08.043, PubMed 18805467

Holten AT, Danbolt NC, Shimamoto K, Gundersen V (2008)
Low-affinity excitatory amino acid uptake in hippocampal astrocytes: a possible role of Na+/dicarboxylate cotransporters
Glia, 56 (9), 990-7
DOI 10.1002/glia.20672, PubMed 18442087

Bergersen LH, Storm-Mathisen J, Gundersen V (2008)
Immunogold quantification of amino acids and proteins in complex subcellular compartments
Nat Protoc, 3 (1), 144-52
DOI 10.1038/nprot.2007.525, PubMed 18193031

Gundersen V (2008)
Co-localization of excitatory and inhibitory transmitters in the brain
Acta Neurol Scand Suppl, 188, 29-33
DOI 10.1111/j.1600-0404.2008.01028.x, PubMed 18439218

Holten AT, Gundersen V (2007)
Glutamine as a precursor for transmitter glutamate, aspartate and GABA in the cerebellum: a role for phosphate-activated glutaminase
J Neurochem, 104 (4), 1032-42
DOI 10.1111/j.1471-4159.2007.05065.x, PubMed 17986214

Nicolaysen A, Gammelsaeter R, Storm-Mathisen J, Gundersen V, Iversen PO (2007)
The components required for amino acid neurotransmitter signaling are present in adipose tissues
J Lipid Res, 48 (10), 2123-32
DOI 10.1194/jlr.M700021-JLR200, PubMed 17600303

Jourdain P, Bergersen LH, Bhaukaurally K, Bezzi P, Santello M, Domercq M, Matute C, Tonello F, Gundersen V, Volterra A (2007)
Glutamate exocytosis from astrocytes controls synaptic strength
Nat Neurosci, 10 (3), 331-9
DOI 10.1038/nn1849, PubMed 17310248

Nguyen NH, Morland C, Gonzalez SV, Rise F, Storm-Mathisen J, Gundersen V, Hassel B (2007)
Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia
J Neurochem, 101 (3), 806-14
DOI 10.1111/j.1471-4159.2006.04397.x, PubMed 17286595

Vikne H, Refsnes PE, Ekmark M, Medbø JI, Gundersen V, Gundersen K (2006)
Muscular performance after concentric and eccentric exercise in trained men
Med Sci Sports Exerc, 38 (10), 1770-81
DOI 10.1249/01.mss.0000229568.17284.ab, PubMed 17019299

Boulland JL, Qureshi T, Seal RP, Rafiki A, Gundersen V, Bergersen LH, Fremeau RT, Edwards RH, Storm-Mathisen J, Chaudhry FA (2004)
Expression of the vesicular glutamate transporters during development indicates the widespread corelease of multiple neurotransmitters
J Comp Neurol, 480 (3), 264-80
DOI 10.1002/cne.20354, PubMed 15515175

Gammelsaeter R, Frøyland M, Aragón C, Danbolt NC, Fortin D, Storm-Mathisen J, Davanger S, Gundersen V (2004)
Glycine, GABA and their transporters in pancreatic islets of Langerhans: evidence for a paracrine transmitter interplay
J Cell Sci, 117 (Pt 17), 3749-58
DOI 10.1242/jcs.01209, PubMed 15252115

Bezzi P, Gundersen V, Galbete JL, Seifert G, Steinhäuser C, Pilati E, Volterra A (2004)
Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate
Nat Neurosci, 7 (6), 613-20
DOI 10.1038/nn1246, PubMed 15156145

Gundersen V, Holten AT, Storm-Mathisen J (2004)
GABAergic synapses in hippocampus exocytose aspartate on to NMDA receptors: quantitative immunogold evidence for co-transmission
Mol Cell Neurosci, 26 (1), 156-65
DOI 10.1016/j.mcn.2004.01.017, PubMed 15121187

Bergersen L, Ruiz A, Bjaalie JG, Kullmann DM, Gundersen V (2003)
GABA and GABAA receptors at hippocampal mossy fibre synapses
Eur J Neurosci, 18 (4), 931-41
DOI 10.1046/j.1460-9568.2003.02828.x, PubMed 12925019

Gundersen V, Fonnum F, Ottersen OP, Storm-Mathisen J (2001)
Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study
J Cereb Blood Flow Metab, 21 (1), 41-51
DOI 10.1097/00004647-200101000-00006, PubMed 11149667

Gundersen V, Chaudhry FA, Bjaalie JG, Fonnum F, Ottersen OP, Storm-Mathisen J (1998)
Synaptic vesicular localization and exocytosis of L-aspartate in excitatory nerve terminals: a quantitative immunogold analysis in rat hippocampus
J Neurosci, 18 (16), 6059-70
PubMed 9698301

Weaver CD, Gundersen V, Verdoorn TA (1998)
A high affinity glutamate/aspartate transport system in pancreatic islets of Langerhans modulates glucose-stimulated insulin secretion
J Biol Chem, 273 (3), 1647-53
DOI 10.1074/jbc.273.3.1647, PubMed 9430708

Gundersen V, Ottersen OP, Storm-Mathisen J (1996)
Selective excitatory amino acid uptake in glutamatergic nerve terminals and in glia in the rat striatum: quantitative electron microscopic immunocytochemistry of exogenous (D)-aspartate and endogenous glutamate and GABA
Eur J Neurosci, 8 (4), 758-65
DOI 10.1111/j.1460-9568.1996.tb01261.x, PubMed 9081627

Gundersen V, Shupliakov O, Brodin L, Ottersen OP, Storm-Mathisen J (1995)
Quantification of excitatory amino acid uptake at intact glutamatergic synapses by immunocytochemistry of exogenous D-aspartate
J Neurosci, 15 (6), 4417-28
PubMed 7790917

Snyder GL, Fisone G, Morino P, Gundersen V, Ottersen OP, Hökfelt T, Greengard P (1993)
Regulation by the neuropeptide cholecystokinin (CCK-8S) of protein phosphorylation in the neostriatum
Proc Natl Acad Sci U S A, 90 (23), 11277-81
DOI 10.1073/pnas.90.23.11277, PubMed 8248241

Gundersen V, Danbolt NC, Ottersen OP, Storm-Mathisen J (1993)
Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous D-aspartate
Neuroscience, 57 (1), 97-111
DOI 10.1016/0306-4522(93)90114-u, PubMed 7904057

Gundersen V, Ottersen OP, Storm-Mathisen J (1991)
Aspartate- and Glutamate-like Immunoreactivities in Rat Hippocampal Slices: Depolarization-induced Redistribution and Effects of Precursors
Eur J Neurosci, 3 (12), 1281-1299
DOI 10.1111/j.1460-9568.1991.tb00061.x, PubMed 12106226

Storm-Mathisen J, Ottersen OP, Fu-Long T, Gundersen V, Laake JH, Nordbø G (1986)
Metabolism and transport of amino acids studied by immunocytochemistry
Med Biol, 64 (2-3), 127-32
PubMed 2875229

Review articles

Gundersen V, Storm-Mathisen J, Bergersen LH (2015)
Neuroglial Transmission
Physiol Rev, 95 (3), 695-726
DOI 10.1152/physrev.00024.2014, PubMed 26084688

Gundersen V (2010)
Protein aggregation in Parkinson's disease
Acta Neurol Scand Suppl (190), 82-7
DOI 10.1111/j.1600-0404.2010.01382.x, PubMed 20586742

Bergersen LH, Gundersen V (2008)
Morphological evidence for vesicular glutamate release from astrocytes
Neuroscience, 158 (1), 260-5
DOI 10.1016/j.neuroscience.2008.03.074, PubMed 18479831

Ottersen OP, Storm-Mathisen J, Bramham C, Torp R, Laake J, Gundersen V (1990)
A quantitative electron microscopic immunocytochemical study of the distribution and synaptic handling of glutamate in rat hippocampus
Prog Brain Res, 83, 99-114
DOI 10.1016/s0079-6123(08)61244-3, PubMed 1975455

Other articles

Jusufovic M, Gundersen V (2017)
[Stooped neck]
Tidsskr Nor Laegeforen, 137 (9), 636
DOI 10.4045/tidsskr.16.0993, PubMed 28468480

Dietrichs E, Gundersen V (2006)
[Glutamate--the most important transmitter in the brain]
Tidsskr Nor Laegeforen, 126 (20), 2643
PubMed 17057761

Gundersen V, Dietrichs E (2000)
Neuroprotection and parkinsonism
Can J Neurol Sci, 27 (3), 261
PubMed 10975542


Gundersen V (1998)
Multivariate signal analysis - empirical modelling of drilling riser feasibility study
Høgskolen i Telemark, Avdeling for teknologiske fag, Porsgrunn, 131 bl.
BIBSYS 981985610


Gundersen V (2002)
Anrikning av Artemia og rotatoria med marine fosfolipider
Institutt for marin bioteknologi, Norges fiskerihøgskole,Universitetet i Tromsø, Tromsø, 57 s.
BIBSYS 023023198

Gundersen V (1995)
The synaptic handling of aspartate at excitatory synapsesin the brain: quantitative light and electron microscopic immunocytochemistry
Department of Anatomy, Institute of Basic Medical Sciences, University of Oslo, [Oslo], 1 b. (flere pag.)
BIBSYS 960233334, ISBN 82-91061-68-8

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