Knut Erik Hovda

  • Consultant MD, PhD
  • +47 23 01 59 22
 

Publications 2019

Miró Ò, Dargan PI, Wood DM, Dines AM, Yates C, Heyerdahl F, Hovda KE, Giraudon I, Euro-DEN Plus Research Group, Galicia M (2019)
Epidemiology, clinical features and management of patients presenting to European emergency departments with acute cocaine toxicity: comparison between powder cocaine and crack cocaine cases
Clin Toxicol (Phila), 1-9 (in press)
DOI 10.1080/15563650.2018.1549735, PubMed 30696283

Wood DM, De La Rue L, Hosin AA, Jurgens G, Liakoni E, Heyerdahl F, Hovda KE, Dines A, Giraudon I, Liechti ME, Dargan PI (2019)
Poor Identification of Emergency Department Acute Recreational Drug Toxicity Presentations Using Routine Hospital Coding Systems: the Experience in Denmark, Switzerland and the UK
J Med Toxicol (in press)
DOI 10.1007/s13181-018-0687-z, PubMed 30603897

Publications 2018

Drangsholt E, Vangstad M, Zakharov S, Hovda KE, Jacobsen D (2018)
The Hypothesis of Circulus Hypoxicus and Its Clinical Relevance in Patients With Methanol Poisoning - An Observational Study of 35 Patients
Basic Clin Pharmacol Toxicol, 123 (6), 749-755
DOI 10.1111/bcpt.13074, PubMed 29923671

Liakoni E, Yates C, Dines AM, Dargan PI, Heyerdahl F, Hovda KE, Wood DM, Eyer F, Liechti ME, Euro-DEN Plus Research Group (2018)
Acute recreational drug toxicity: Comparison of self-reports and results of immunoassay and additional analytical methods in a multicenter European case series
Medicine (Baltimore), 97 (5), e9784
DOI 10.1097/MD.0000000000009784, PubMed 29384873

Lyphout C, Yates C, Margolin ZR, Dargan PI, Dines AM, Heyerdahl F, Hovda KE, Giraudon I, Bucher-Bartelson B, Green JL, Euro-DEN Research Group, Wood DM (2018)
Presentations to the emergency department with non-medical use of benzodiazepines and Z-drugs: profiling and relation to sales data
Eur J Clin Pharmacol, 75 (1), 77-85
DOI 10.1007/s00228-018-2550-1, PubMed 30244371

Miro O, Yates C, Dines AM, Wood DM, Dargan PI, Galan I, Jerez A, Puiguriguer J, Waring WS, Moughty A, O'Connor N, Heyerdahl F, Hovda KE, Vallersnes OM, Paasma R, Pold K, Jurgens G, Megarbane B, Anand JS, Liakoni E, Liechti M, Eyer F, Zacharov S, Caganova B, Giraudon I et al. (2018)
Emergencies related to recreational drug abuse in Spain compared to emergencies attended in 3 European areas
Emergencias, 30 (6), 385-394

Yamamoto T, Dargan PI, Dines A, Yates C, Heyerdahl F, Hovda KE, Giraudon I, Sedefov R, Wood DM, Euro-DEN Research Group (2018)
Concurrent Use of Benzodiazepine by Heroin Users-What Are the Prevalence and the Risks Associated with This Pattern of Use?
J Med Toxicol, 15 (1), 4-11
DOI 10.1007/s13181-018-0674-4, PubMed 30066312

Publications 2017

Miró Ò, Galicia M, Dargan P, Dines AM, Giraudon I, Heyerdahl F, Hovda KE, Yates C, Wood DM, Liakoni E, Liechti M, Jürgens G, Pedersen CB, O'Connor N, Markey G, Moughty A, Lee C, O'Donohoe P, Sein Anand J, Puiguriguer J, Homar C, Eyer F, Vallersnes OM, Persett PS, Chevillard L et al. (2017)
Intoxication by gamma hydroxybutyrate and related analogues: Clinical characteristics and comparison between pure intoxication and that combined with other substances of abuse
Toxicol Lett, 277, 84-91
DOI 10.1016/j.toxlet.2017.05.030, PubMed 28579487

Vallersnes OM, Persett PS, Øiestad EL, Karinen R, Heyerdahl F, Hovda KE (2017)
Underestimated impact of novel psychoactive substances: laboratory confirmation of recreational drug toxicity in Oslo, Norway
Clin Toxicol (Phila), 55 (7), 636-644
DOI 10.1080/15563650.2017.1312002, PubMed 28406320

Zakharov S, Roberts DM, Hovda KE (2017)
Reply to "Letter in response to efficiency of acidemia correction on intermittent versus continuous hemodialysis in acute methanol poisoning"
Clin Toxicol (Phila), 55 (4), 306-307
DOI 10.1080/15563650.2017.1284338, PubMed 28206824

Zakharov S, Rulisek J, Nurieva O, Kotikova K, Navratil T, Komarc M, Pelclova D, Hovda KE (2017)
Intermittent versus continuous renal replacement therapy in acute methanol poisoning: comparison of clinical effectiveness in mass poisoning outbreaks
Ann Intensive Care, 7 (1), 77
DOI 10.1186/s13613-017-0300-7, PubMed 28730555

Publications 2016

McMartin K, Jacobsen D, Hovda KE (2016)
Antidotes for poisoning by alcohols that form toxic metabolites
Br J Clin Pharmacol, 81 (3), 505-15
DOI 10.1111/bcp.12824, PubMed 26551875

Rostrup M, Edwards JK, Abukalish M, Ezzabi M, Some D, Ritter H, Menge T, Abdelrahman A, Rootwelt R, Janssens B, Lind K, Paasma R, Hovda KE (2016)
The Methanol Poisoning Outbreaks in Libya 2013 and Kenya 2014
PLoS One, 11 (3), e0152676
DOI 10.1371/journal.pone.0152676, PubMed 27030969

Rostrup M, Edwards JK, Abukalish M, Ezzabi M, Some D, Ritter H, Menge T, Abdelrahman A, Rootwelt R, Janssens B, Lind K, Paasma R, Hovda KE (2016)
Correction: The Methanol Poisoning Outbreaks in Libya 2013 and Kenya 2014
PLoS One, 11 (6), e0157256
DOI 10.1371/journal.pone.0157256, PubMed 27257672

Vallersnes OM, Dines AM, Wood DM, Yates C, Heyerdahl F, Hovda KE, Giraudon I, Euro-DEN Research Group, Dargan PI (2016)
Erratum to: Psychosis associated with acute recreational drug toxicity: a European case series
BMC Psychiatry, 16 (1), 405
DOI 10.1186/s12888-016-1066-4, PubMed 27852244

Vallersnes OM, Dines AM, Wood DM, Yates C, Heyerdahl F, Hovda KE, Giraudon I, Euro-DEN Research Group, Dargan PI (2016)
Psychosis associated with acute recreational drug toxicity: a European case series
BMC Psychiatry, 16, 293
DOI 10.1186/s12888-016-1002-7, PubMed 27538886

Wood DM, Dines AM, Heyerdahl F, Yates C, Giraudon I, Paasma R, Hovda KE, Dargan PI (2016)
Review of European- Drug Emergencies Network ( Euro- DEN) training package for non- specialist workers to assess acute recreational drug and new psychoactive substance toxicity in night- time economy environments
Drug-Educ. Prev. Policy, 23 (1), 73-77

Zakharov S, Pelclova D, Navratil T, Belacek J, Latta J, Pisar M, Rulisek J, Leps J, Zidek P, Kucera C, Bocek R, Mazur M, Belik Z, Chalupa J, Talafa V, Kodras K, Nalos D, Sedlak C, Senkyrik M, Smid J, Salek T, Roberts DM, Hovda KE (2016)
Efficiency of acidemia correction on intermittent versus continuous hemodialysis in acute methanol poisoning
Clin Toxicol (Phila), 55 (2), 123-132
DOI 10.1080/15563650.2016.1250901, PubMed 27817225

Zakharov S, Pelclova D, Urban P, Navratil T, Nurieva O, Kotikova K, Diblik P, Kurcova I, Belacek J, Komarc M, Eddleston M, Hovda KE (2016)
Use of Out-of-Hospital Ethanol Administration to Improve Outcome in Mass Methanol Outbreaks
Ann Emerg Med, 68 (1), 52-61
DOI 10.1016/j.annemergmed.2016.01.010, PubMed 26875060

Publications 2015

Dalaker VM, Vallersnes OM, Fosshaug LE, Andersson KS, Hovda KE (2015)
A young woman who drank Strep test reagents
Tidsskr Nor Laegeforen, 135 (22), 2067-70
DOI 10.4045/tidsskr.15.0190, PubMed 26627296

Dines AM, Wood DM, Galicia M, Yates CM, Heyerdahl F, Hovda KE, Giraudon I, Sedefov R, Euro-DEN Research Group, Dargan PI (2015)
Presentations to the Emergency Department Following Cannabis use--a Multi-Centre Case Series from Ten European Countries
J Med Toxicol, 11 (4), 415-21
DOI 10.1007/s13181-014-0460-x, PubMed 25652342

Dines AM, Wood DM, Yates C, Heyerdahl F, Hovda KE, Giraudon I, Sedefov R, Dargan PI, Euro-DEN Research Group (2015)
Acute recreational drug and new psychoactive substance toxicity in Europe: 12 months data collection from the European Drug Emergencies Network (Euro-DEN)
Clin Toxicol (Phila), 53 (9), 893-900
DOI 10.3109/15563650.2015.1088157, PubMed 26503789

Hovda KE, Gadeholt G, Evtodienko V, Jacobsen D (2015)
A novel bedside diagnostic test for methanol poisoning using dry chemistry for formate
Scand J Clin Lab Invest, 75 (7), 610-4
DOI 10.3109/00365513.2015.1066847, PubMed 26203958

Zakharov S, Pelclova D, Diblik P, Urban P, Kuthan P, Nurieva O, Kotikova K, Navratil T, Komarc M, Belacek J, Seidl Z, Vaneckova M, Hubacek JA, Bezdicek O, Klempir J, Yurchenko M, Ruzicka E, Miovsky M, Janikova B, Hovda KE (2015)
Long-term visual damage after acute methanol poisonings: Longitudinal cross-sectional study in 50 patients
Clin Toxicol (Phila), 53 (9), 884-92
DOI 10.3109/15563650.2015.1086488, PubMed 26364866

Zakharov S, Pelclova D, Navratil T, Belacek J, Komarc M, Eddleston M, Hovda KE (2015)
Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak
Clin Toxicol (Phila), 53 (8), 797-806
DOI 10.3109/15563650.2015.1059946, PubMed 26109326

Publications 2014

Heyerdahl F, Hovda KE, Giraudon I, Yates C, Dines AM, Sedefov R, Wood DM, Dargan PI (2014)
Current European data collection on emergency department presentations with acute recreational drug toxicity: gaps and national variations
Clin Toxicol (Phila), 52 (10), 1005-12
DOI 10.3109/15563650.2014.976792, PubMed 25361166

Wood DM, Heyerdahl F, Yates CB, Dines AM, Giraudon I, Hovda KE, Dargan PI (2014)
The European Drug Emergencies Network (Euro-DEN)
Clin Toxicol (Phila), 52 (4), 239-41
DOI 10.3109/15563650.2014.898771, PubMed 24654801

Zakharov S, Pelclova D, Navratil T, Belacek J, Kurcova I, Komzak O, Salek T, Latta J, Turek R, Bocek R, Kucera C, Hubacek JA, Fenclova Z, Petrik V, Cermak M, Hovda KE (2014)
Intermittent hemodialysis is superior to continuous veno-venous hemodialysis/hemodiafiltration to eliminate methanol and formate during treatment for methanol poisoning
Kidney Int, 86 (1), 199-207
DOI 10.1038/ki.2014.60, PubMed 24621917

Zakharov S, Pelclova D, Urban P, Navratil T, Diblik P, Kuthan P, Hubacek JA, Miovsky M, Klempir J, Vaneckova M, Seidl Z, Pilin A, Fenclova Z, Petrik V, Kotikova K, Nurieva O, Ridzon P, Rulisek J, Komarc M, Hovda KE (2014)
Czech mass methanol outbreak 2012: epidemiology, challenges and clinical features
Clin Toxicol (Phila), 52 (10), 1013-24
DOI 10.3109/15563650.2014.974106, PubMed 25345388

Publications 2013

Krayeva YV, Brusin KM, Bushuev AV, Kondrashov DL, Sentsov VG, Hovda KE (2013)
Pre-hospital management and outcome of acute poisonings by ambulances in Yekaterinburg, Russia
Clin Toxicol (Phila), 51 (8), 752-60
DOI 10.3109/15563650.2013.827707, PubMed 23937527

Lund C, Bjornaas MA, Sandvik L, Ekeberg O, Jacobsen D, Hovda KE (2013)
Five-year mortality after acute poisoning treated in ambulances, an emergency outpatient clinic and hospitals in Oslo
Scand J Trauma Resusc Emerg Med, 21, 65
DOI 10.1186/1757-7241-21-65, PubMed 23965589

Paasma R, Hovda KE, Hassanian-Moghaddan H, Brahmi N, Afshari R, Sandvik L, Jacobsen D (2013)
Response to the letter "Risk assessment of methanol poisoning in outbreaks not applicable to isolated cases"
Clin Toxicol (Phila), 51 (2), 120
DOI 10.3109/15563650.2013.764430, PubMed 23339630

Publications 2012

Lund C, Drottning P, Stiksrud B, Vahabi J, Lyngra M, Ekeberg I, Jacobsen D, Hovda KE (2012)
A one-year observational study of all hospitalized acute poisonings in Oslo: complications, treatment and sequelae
Scand J Trauma Resusc Emerg Med, 20, 49
DOI 10.1186/1757-7241-20-49, PubMed 22828054

Lund C, Teige B, Drottning P, Stiksrud B, Rui TO, Lyngra M, Ekeberg O, Jacobsen D, Hovda KE (2012)
A one-year observational study of all hospitalized and fatal acute poisonings in Oslo: epidemiology, intention and follow-up
BMC Public Health, 12, 858
DOI 10.1186/1471-2458-12-858, PubMed 23046743

Lund C, Vallersnes OM, Jacobsen D, Ekeberg O, Hovda KE (2012)
Outpatient treatment of acute poisonings in Oslo: poisoning pattern, factors associated with hospitalization, and mortality
Scand J Trauma Resusc Emerg Med, 20, 1
DOI 10.1186/1757-7241-20-1, PubMed 22217253

Paasma R, Hovda KE, Hassanian-Moghaddam H, Brahmi N, Afshari R, Sandvik L, Jacobsen D (2012)
Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes--a multicenter study
Clin Toxicol (Phila), 50 (9), 823-31
DOI 10.3109/15563650.2012.728224, PubMed 22992104

Publications 2011

Hovda KE, Julsrud J, Øvrebø S, Brørs O, Jacobsen D (2011)
Studies on ethylene glycol poisoning: one patient - 154 admissions
Clin Toxicol (Phila), 49 (6), 478-84
DOI 10.3109/15563650.2011.590140, PubMed 21824058

Kolvik HM, Heyerdahl F, Bjørnaas MA, Hovda KE, Jacobsen D, Ekeberg Ø (2011)
[Living conditions and pattern of acute poisonings in Oslo]
Tidsskr Nor Laegeforen, 131 (15), 1424-8
DOI 10.4045/tidsskr.10.0531, PubMed 21844943

Publications 2010

Bjornaas MA, Hovda KE, Heyerdahl F, Skog K, Drottning P, Opdahl A, Jacobsen D, Ekeberg O (2010)
Suicidal intention, psychosocial factors and referral to further treatment: a one-year cross-sectional study of self-poisoning
BMC Psychiatry, 10, 58
DOI 10.1186/1471-244X-10-58, PubMed 20653986

Bjornaas MA, Teige B, Hovda KE, Ekeberg O, Heyerdahl F, Jacobsen D (2010)
Fatal poisonings in Oslo: a one-year observational study
BMC Emerg Med, 10, 13
DOI 10.1186/1471-227X-10-13, PubMed 20525396

Publications 2009

Heyerdahl F, Bjornaas MA, Dahl R, Hovda KE, Nore AK, Ekeberg O, Jacobsen D (2009)
Repetition of acute poisoning in Oslo: 1-year prospective study
Br J Psychiatry, 194 (1), 73-9
DOI 10.1192/bjp.bp.107.048322, PubMed 19118331

Hovda KE, Guo C, Austin R, McMartin KE (2009)
Renal toxicity of ethylene glycol results from internalization of calcium oxalate crystals by proximal tubule cells
Toxicol Lett, 192 (3), 365-72
DOI 10.1016/j.toxlet.2009.11.013, PubMed 19931368

Paasma R, Hovda KE, Jacobsen D (2009)
Methanol poisoning and long term sequelae - a six years follow-up after a large methanol outbreak
BMC Clin Pharmacol, 9, 5
DOI 10.1186/1472-6904-9-5, PubMed 19327138

Publications 2008

Heyerdahl F, Bjornas MA, Hovda KE, Skog K, Opdahl A, Wium C, Ekeberg O, Jacobsen D (2008)
Acute poisonings treated in hospitals in Oslo: a one-year prospective study (II): clinical outcome
Clin Toxicol (Phila), 46 (1), 42-9
DOI 10.1080/15563650701210048, PubMed 18167036

Heyerdahl F, Hovda KE, Bjornaas MA, Brørs O, Ekeberg O, Jacobsen D (2008)
Clinical assessment compared to laboratory screening in acutely poisoned patients
Hum Exp Toxicol, 27 (1), 73-9
DOI 10.1177/0960327107087800, PubMed 18480152

Heyerdahl F, Hovda KE, Bjornaas MA, Nore AK, Figueiredo JC, Ekeberg O, Jacobsen D (2008)
Pre-hospital treatment of acute poisonings in Oslo
BMC Emerg Med, 8, 15
DOI 10.1186/1471-227X-8-15, PubMed 19025643

Hovda KE, Bjornaas MA, Skog K, Opdahl A, Drottning P, Ekeberg O, Jacobsen D (2008)
Acute poisonings treated in hospitals in Oslo: a one-year prospective study (I): pattern of poisoning
Clin Toxicol (Phila), 46 (1), 35-41
DOI 10.1080/15563650601185969, PubMed 18167035

Hovda KE, Jacobsen D (2008)
Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning
Hum Exp Toxicol, 27 (7), 539-46
DOI 10.1177/0960327108095992, PubMed 18829729

Publications 2007

Hovda KE, Mundal H, Urdal P, McMartin K, Jacobsen D (2007)
Extremely slow formate elimination in severe methanol poisoning: a fatal case report
Clin Toxicol (Phila), 45 (5), 516-21
DOI 10.1080/15563650701354150, PubMed 17503258

Paasma R, Hovda KE, Tikkerberi A, Jacobsen D (2007)
Methanol mass poisoning in Estonia: outbreak in 154 patients
Clin Toxicol (Phila), 45 (2), 152-7
DOI 10.1080/15563650600956329, PubMed 17364632

Rajka T, Heyerdahl F, Hovda KE, Stiksrud B, Jacobsen D (2007)
Acute child poisonings in Oslo: a 2-year prospective study
Acta Paediatr, 96 (9), 1355-9
DOI 10.1111/j.1651-2227.2007.00420.x, PubMed 17718791

Publications 2006

Bjornaas MA, Hovda KE, Mikalsen H, Andrew E, Rudberg N, Ekeberg O, Jacobsen D (2006)
Clinical vs. laboratory identification of drugs of abuse in patients admitted for acute poisoning
Clin Toxicol (Phila), 44 (2), 127-34
DOI 10.1080/15563650500514384, PubMed 16615667

Hunderi OH, Hovda KE, Jacobsen D (2006)
Use of the osmolal gap to guide the start and duration of dialysis in methanol poisoning
Scand J Urol Nephrol, 40 (1), 70-4
DOI 10.1080/00365590500190755, PubMed 16452060

Publications 2005

Hovda KE, Andersson KS, Urdal P, Jacobsen D (2005)
Methanol and formate kinetics during treatment with fomepizole
Clin Toxicol (Phila), 43 (4), 221-7
PubMed 16035197

Hovda KE, Froyshov S, Gudmundsdottir H, Rudberg N, Jacobsen D (2005)
Fomepizole may change indication for hemodialysis in methanol poisoning: prospective study in seven cases
Clin Nephrol, 64 (3), 190-7
PubMed 16175943

Hovda KE, Hunderi OH, Tafjord AB, Dunlop O, Rudberg N, Jacobsen D (2005)
Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signs
J Intern Med, 258 (2), 181-90
DOI 10.1111/j.1365-2796.2005.01521.x, PubMed 16018795

Hovda KE, Urdal P, Jacobsen D (2005)
Increased serum formate in the diagnosis of methanol poisoning
J Anal Toxicol, 29 (6), 586-8
DOI 10.1093/jat/29.6.586, PubMed 16168185

Publications 2004

Hovda KE, Hunderi OH, Rudberg N, Froyshov S, Jacobsen D (2004)
Anion and osmolal gaps in the diagnosis of methanol poisoning: clinical study in 28 patients
Intensive Care Med, 30 (9), 1842-6
DOI 10.1007/s00134-004-2373-7, PubMed 15241587

Hovda KE, Hunderi OH, Øvrebø S, Jacobsen D (2004)
[Diagnosis in metabolic acidosis of unknown origin]
Tidsskr Nor Laegeforen, 124 (24), 3203-5
PubMed 15608766

Hunderi OH, Hovda KE, Lie B, Listerud S, Hartmann A, Jacobsen D (2004)
[Methanol poisoning in Norway 2002]
Tidsskr Nor Laegeforen, 124 (24), 3199-202
PubMed 15608765

Publications 2003

Server A, Hovda KE, Nakstad PH, Jacobsen D, Dullerud R, Haakonsen M (2003)
Conventional and diffusion-weighted MRI in the evaluation of methanol poisoning
Acta Radiol, 44 (6), 691-5
DOI 10.1046/j.1600-0455.2003.00138.x, PubMed 14616218

Publications 1998

Hovda KE, Liberg JP, Nordby G, Jacobsen D (1998)
[Gamma-hydroxybutyrate--an endogenous substance and an intoxicant]
Tidsskr Nor Laegeforen, 118 (28), 4390-3
PubMed 9889613

Liberg JP, Hovda KE, Nordby G, Jacobsen D (1998)
[Ecstasy--cool dope with long-lasting effects?]
Tidsskr Nor Laegeforen, 118 (28), 4384-7
PubMed 9889612

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