
Geir Øystein Andersen
- MD, PhD
- +472119100
1)Leaf (Safety and efficacy of levosimendan in patients with acute myocardial infarction complicated by symptomatic left ventricular failure)
2)Biobanking in patients with myocardial infarction (BAMI)
Publications 2020
Neutrophil extracellular trap components and myocardial recovery in post-ischemic acute heart failure
PLoS One, 15 (10), e0241333
DOI 10.1371/journal.pone.0241333, PubMed 33119664
Double-Stranded DNA and NETs Components in Relation to Clinical Outcome After ST-Elevation Myocardial Infarction
Sci Rep, 10 (1), 5007
DOI 10.1038/s41598-020-61971-7, PubMed 32193509
Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
Resuscitation, 149, 170-179
DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
EBioMedicine, 60, 102985
DOI 10.1016/j.ebiom.2020.102985, PubMed 32927275
Lower ST-elevation myocardial infarction incidence during COVID-19 epidemic in Northern Europe
Scand Cardiovasc J, 54 (6), 358-360
DOI 10.1080/14017431.2020.1820563, PubMed 32945201
Clinical impact of chronic substance abuse in a Norwegian ICU-population
Acta Anaesthesiol Scand, 65 (4), 515-524
DOI 10.1111/aas.13766, PubMed 33340102
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353
Publications 2019
Rationale for the ASSAIL-MI-trial: a randomised controlled trial designed to assess the effect of tocilizumab on myocardial salvage in patients with acute ST-elevation myocardial infarction (STEMI)
Open Heart, 6 (2), e001108
DOI 10.1136/openhrt-2019-001108, PubMed 31673391
MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI (vol 13, e0206723, 2018)
PLoS One, 14 (3), e0213636
Glucose associated NETosis in patients with ST-elevation myocardial infarction: an observational study
BMC Cardiovasc Disord, 19 (1), 221
DOI 10.1186/s12872-019-1205-1, PubMed 31615411
Neutrophil Extracellular Trap Components Associate with Infarct Size, Ventricular Function, and Clinical Outcome in STEMI
Mediators Inflamm, 2019, 7816491
DOI 10.1155/2019/7816491, PubMed 31772506
Esmolol for cardioprotection during resuscitation with adrenaline in an ischaemic porcine cardiac arrest model
Intensive Care Med Exp, 7 (1), 65
DOI 10.1186/s40635-019-0279-5, PubMed 31802327
IgM antibodies against phosphorylcholine measured early after acute ST-elevation myocardial infarction in relation to atherosclerotic disease burden and long-term clinical outcome
PLoS One, 14 (4), e0215640
DOI 10.1371/journal.pone.0215640, PubMed 31002684
Long-Term Survival after Invasive or Conservative Strategy in Elderly Patients with non-ST-Elevation Myocardial Infarction: A Prospective Cohort Study
Cardiology, 144 (3-4), 79-89
DOI 10.1159/000503442, PubMed 31689705
Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages
Atherosclerosis, 296, 74-82
DOI 10.1016/j.atherosclerosis.2019.12.008, PubMed 31870625
Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
Cardiovasc Res, 115 (4), 752-764
DOI 10.1093/cvr/cvy257, PubMed 30351410
Publications 2018
Microvascular perfusion in infarcted and remote myocardium after successful primary PCI: angiographic and CMR findings
Eur Radiol, 29 (2), 941-950
DOI 10.1007/s00330-018-5588-7, PubMed 29980929
MR findings of microvascular perfusion in infarcted and remote myocardium early after successful primary PCI
PLoS One, 13 (11), e0206723
DOI 10.1371/journal.pone.0206723, PubMed 30412607
Markers of Thrombin Generation Are Associated With Long-Term Clinical Outcome in Patients With ST-Segment Elevation Myocardial Infarction
Clin Appl Thromb Hemost, 24 (7), 1088-1094
DOI 10.1177/1076029618764847, PubMed 29695176
Hypothermia elongates the contraction-relaxation cycle in explanted human failing heart decreasing the time for ventricular filling during diastole
Am J Physiol Heart Circ Physiol, 315 (5), H1137-H1147
DOI 10.1152/ajpheart.00208.2018, PubMed 30004809
Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
ESC Heart Fail, 5 (3), 292-301
DOI 10.1002/ehf2.12266, PubMed 29424484
IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
Front Immunol, 9, 2035
DOI 10.3389/fimmu.2018.02035, PubMed 30258440
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
Int J Cardiol, 268, 187-192
DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279
Association of IL-8 With Infarct Size and Clinical Outcomes in Patients With STEMI
J Am Coll Cardiol, 72 (2), 187-198
DOI 10.1016/j.jacc.2018.04.053, PubMed 29976293
Comparison of three haemodynamic monitoring methods in comatose post cardiac arrest patients
Scand Cardiovasc J, 52 (3), 141-148
DOI 10.1080/14017431.2018.1450992, PubMed 29544369
Publications 2017
Systolic mitral annulus velocity is a sensitive index for changes in left ventricular systolic function during inotropic therapy in patients with acute heart failure
Eur Heart J Acute Cardiovasc Care, 7 (4), 321-329
DOI 10.1177/2048872616687114, PubMed 28045338
Long-term survival in patients with acute myocardial infarction and out-of-hospital cardiac arrest: A prospective cohort study
Resuscitation, 122, 41-47
DOI 10.1016/j.resuscitation.2017.11.047, PubMed 29155294
Evaluation of circulating levels of CCN2/connective tissue growth factor in patients with ST-elevation myocardial infarction
Sci Rep, 7 (1), 11945
DOI 10.1038/s41598-017-12372-w, PubMed 28931920
Osteoprotegerin levels in ST-elevation myocardial infarction: Temporal profile and association with myocardial injury and left ventricular function
PLoS One, 12 (3), e0173034
DOI 10.1371/journal.pone.0173034, PubMed 28253327
Publications 2016
Impact of acute kidney injury on patient outcome in out-of-hospital cardiac arrest: a prospective observational study
Acta Anaesthesiol Scand, 60 (8), 1170-81
DOI 10.1111/aas.12753, PubMed 27306254
Urine biomarkers give early prediction of acute kidney injury and outcome after out-of-hospital cardiac arrest
Crit Care, 20 (1), 314
DOI 10.1186/s13054-016-1503-2, PubMed 27716377
Monocyte-derived circulating microparticles (CD14+, CD14+/CD11b+ and CD14+/CD142+) are related to long-term prognosis for cardiovascular mortality in STEMI patients
Int J Cardiol, 227, 876-881
DOI 10.1016/j.ijcard.2016.11.302, PubMed 27915085
Circulating Levels of IL-6 Receptor and gp130 and Long-Term Clinical Outcomes in ST-Elevation Myocardial Infarction
J Am Heart Assoc, 5 (6)
DOI 10.1161/JAHA.115.003014, PubMed 27412895
Publications 2015
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages
Atherosclerosis, 243 (1), 204-10
DOI 10.1016/j.atherosclerosis.2015.09.010, PubMed 26402139
Markers of thrombin generation are associated with myocardial necrosis and left ventricular impairment in patients with ST-elevation myocardial infarction
Thromb J, 13, 31
DOI 10.1186/s12959-015-0061-1, PubMed 26396552
Influence of ischemic postconditioning on myocardial dysfunction measured by speckle tracking echocardiography in patients with ST-elevation myocardial infarction
Int J Cardiol, 187, 459-61
DOI 10.1016/j.ijcard.2015.03.192, PubMed 25846653
The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium
PLoS One, 10 (3), e0115547
DOI 10.1371/journal.pone.0115547, PubMed 25738589
Post-Resuscitation ECG for Selection of Patients for Immediate Coronary Angiography in Out-of-Hospital Cardiac Arrest
Circ Cardiovasc Interv, 8 (10)
DOI 10.1161/CIRCINTERVENTIONS.115.002784, PubMed 26453688
The authors reply
Crit Care Med, 43 (3), e98
DOI 10.1097/CCM.0000000000000812, PubMed 25700077
Prediction of outcome after out-of-hospital cardiac arrest already on hospital admission-not reliable enough to be true!
Eur Heart J, 37 (42), 3229-3231
DOI 10.1093/eurheartj/ehv490, PubMed 26516178
Publications 2014
Circulatory shock
N Engl J Med, 370 (6), 583
DOI 10.1056/NEJMc1314999, PubMed 24499234
Association of interleukin 8 and myocardial recovery in patients with ST-elevation myocardial infarction complicated by acute heart failure
PLoS One, 9 (11), e112359
DOI 10.1371/journal.pone.0112359, PubMed 25390695
Effect of ischemic postconditioning on infarct size in patients with ST-elevation myocardial infarction treated by primary PCI results of the POSTEMI (POstconditioning in ST-Elevation Myocardial Infarction) randomized trial
J Am Heart Assoc, 3 (2), e000679
DOI 10.1161/JAHA.113.000679, PubMed 24760962
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart
Br J Pharmacol, 171 (23), 5169-81
DOI 10.1111/bph.12647, PubMed 24547784
Bradycardia during therapeutic hypothermia is associated with good neurologic outcome in comatose survivors of out-of-hospital cardiac arrest
Crit Care Med, 42 (11), 2401-8
DOI 10.1097/CCM.0000000000000515, PubMed 25072762
Publications 2013
Levosimendan in acute heart failure following primary percutaneous coronary intervention-treated acute ST-elevation myocardial infarction. Results from the LEAF trial: a randomized, placebo-controlled study
Eur J Heart Fail, 15 (5), 565-72
DOI 10.1093/eurjhf/hfs215, PubMed 23288914
Myocardial salvage is reduced in primary PCI-treated STEMI patients with microvascular obstruction, demonstrated by early and late CMR
PLoS One, 8 (8), e71780
DOI 10.1371/journal.pone.0071780, PubMed 23977143
Publications 2012
Increased circulating mitochondrial DNA after myocardial infarction
Int J Cardiol, 158 (1), 132-4
DOI 10.1016/j.ijcard.2012.04.047, PubMed 22578950
Publications 2011
Elevated serum osteoprotegerin levels measured early after acute ST-elevation myocardial infarction predict final infarct size
Heart, 97 (6), 460-5
DOI 10.1136/hrt.2010.206714, PubMed 21270073
Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction: potential counteracting effects of activin A on inflammation
Diabetes, 60 (5), 1544-51
DOI 10.2337/db10-1493, PubMed 21464440
Impact of newly diagnosed abnormal glucose regulation on long-term prognosis in low risk patients with ST-elevation myocardial infarction: A follow-up study
BMC Endocr Disord, 11, 14
DOI 10.1186/1472-6823-11-14, PubMed 21801387
Elevated levels of PAI-1 activity and t-PA antigen are associated with newly diagnosed abnormal glucose regulation in patients with ST-elevation myocardial infarction
J Thromb Haemost, 9 (8), 1468-74
DOI 10.1111/j.1538-7836.2011.04377.x, PubMed 21624046
Strong and weak aspects of an established post-resuscitation treatment protocol-A five-year observational study
Resuscitation, 82 (9), 1186-93
DOI 10.1016/j.resuscitation.2011.05.003, PubMed 21636202
Publications 2010
Increased levels of CRP and MCP-1 are associated with previously unknown abnormal glucose regulation in patients with acute STEMI: a cohort study
Cardiovasc Diabetol, 9, 47
DOI 10.1186/1475-2840-9-47, PubMed 20809989
Rationale and design of the POSTEMI (postconditioning in ST-elevation myocardial infarction) study
Cardiology, 116 (2), 103-9
DOI 10.1159/000316965, PubMed 20588018
Publications 2009
Abnormal glucose regulation in patients with acute ST- elevation myocardial infarction-a cohort study on 224 patients
Cardiovasc Diabetol, 8, 6
DOI 10.1186/1475-2840-8-6, PubMed 19183453
Publications 2008
Treatment of acute decompensated heart failure: harmful effects of high doses of loop diuretics?
Cardiology, 113 (1), 9-11
DOI 10.1159/000164148, PubMed 18931491
Publications 2007
Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
Mol Pharmacol, 72 (3), 582-91
DOI 10.1124/mol.107.035766, PubMed 17573483
Publications 2005
[Cardiogenic shock-- new therapeutic strategies]
Tidsskr Nor Laegeforen, 125 (10), 1318-21
PubMed 15909001
Publications 2004
RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin
J Mol Cell Cardiol, 38 (1), 145-51
DOI 10.1016/j.yjmcc.2004.10.009, PubMed 15623431
Ca2+-dependent elevation of inositol 1,4,5-trisphosphate level induced by freezing or homogenization of tissues and cells
Basic Clin Pharmacol Toxicol, 95 (6), 288-94
DOI 10.1111/j.1742-7843.2004.t01-1-pto950507.x, PubMed 15569274