Welcome to Group of Urological Molecular Biology
Group of Urological Molecular Biology was established in 2001 at Oslo Urological University Clinic and moved in 2010 to Department of Tumor Biology.
Prostate cancer is the most common male malignancy in Norway and the number of men diagnosed with prostate cancer is rapidly increasing. About one third of the patients receive curative treatment meaning surgery or radiation. However, many patients will experience more problems due to the treatment then the cancer itself. This is a dilemma for the urologists as they can’t tell whether a histological proven tumor will give rise to a clinically significant disease. Thus, over treatment of prostate cancer patients with non-aggressive disease is a major problem both for the patients and the health care system. In collaboration with Department of Urology and Department of Pathology, the Group of Urological Molecular Biology is studying the molecular mechanisms involved in progression to castration resistant prostate cancer (also called hormone refractory or androgen-independent) in order to identify molecular biomarkers of aggressive disease and new drug targets.
The leader of the group is senior scientist Kristin Austlid Taskén (PhD), who also holds a position as adjunct professor at Department of Urology.
Prostate cancer is the most common male malignancy in Norway and the number of men diagnosed with prostate cancer is rapidly increasing. About one third of the patients receive curative treatment meaning surgery or radiation. However, many patients will experience more problems due to the treatment then the cancer itself. This is a dilemma for the urologists as they can’t tell whether a histological proven tumor will give rise to a clinically significant disease. Thus, over treatment of prostate cancer patients with non-aggressive disease is a major problem both for the patients and the health care system. In collaboration with Department of Urology and Department of Pathology, the Group of Urological Molecular Biology is studying the molecular mechanisms involved in progression to castration resistant prostate cancer (also called hormone refractory or androgen-independent) in order to identify molecular biomarkers of aggressive disease and new drug targets.
The leader of the group is senior scientist Kristin Austlid Taskén (PhD), who also holds a position as adjunct professor at Department of Urology.
News & events
Study by Ane Hansen Kjenseth et al. featured on the cover of Journal of Biological Chemistry
May 7, 2012
More news
May 7, 2012
Latest publications
Kristin Austlid Taskčn
The effects of short-term genistein intervention on prostate biomarker expression in patients with localised prostate cancer before radical prostatectomy
Br J Nutr, 1-10 (in press)
PubMed 22397815
Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial
Nutr Cancer, 63 (6), 889-98
PubMed 21714686
Regulation of PBX3 expression by androgen and Let-7d in prostate cancer
Mol Cancer, 10, 50
PubMed 21548940
More publications






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