Welcome to the web site of Elisabeth Larsen’s group
Laboratory of Embryonic Stem Cell Research
Institute of Medical Microbiology, Section for Molecular Biology, is located at the National Hospital at Gaustad, Oslo.
Our aim is to model human diseases using induced pluripotent stem cells (iPSC).
Currently we are working on reprogramming cells from patients suffering from Huntington disease to iPSC. Also, we are in the process of reprogramming fibroblasts from patients with different genetic imprinting disorders. Furthermore, by using embryonic stem cells derived from knockout animals lacking enzymes involved in epigenetic regulation, we try to elucidate mechanisms regulating pluripotency and self-renewal.
We do have a close collaboration with professor Arne Klungland (the National Hospital, Oslo, Norway), professor Jennie Lee (Harvard Medical School, Boston, USA) and professor Mary Donohoe (Weill Cornell Medical College, New York, USA).
Jørgen Wesche appointed group leader for the Mesenchymal Cancer Biology Group at the Department of Tumor Biology
Mar 15, 2017
Prestigious research prize from the Norwegian Cancer Society to pioneer in autophagy research
Mar 7, 2017
Mar 6, 2017
Mar 2, 2017
Role of ALKBH1 in the Core Transcriptional Network of Embryonic Stem Cells
Cell Physiol Biochem, 38 (1), 173-84
Non-homologous functions of the AlkB homologs
J Mol Cell Biol, 7 (6), 494-504
Oxidative stress causes DNA triplet expansion in Huntington's disease mouse embryonic stem cells
Stem Cell Res, 11 (3), 1264-71