Christian Naper
Position: Head physician
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Author network for Christian Naper by COREMINE medical


Publications 2017

Boieri M, Shah P, Jalapothu D, Zaitseva O, Walter L, Rolstad B, Naper C, Dressel R, Inngjerdingen M (2017)
Rat acute GvHD is Th1 driven and characterized by predominant donor CD4(+) T-cell infiltration of skin and gut
Exp Hematol (in press)
PubMed 28238806

Koefoed-Nielsen P, Weinreich I, Bengtsson M, Lauronen J, Naper C, Gäbel M, Sørensen SS, Wennberg L, Reisaeter AV, Møller BK, Nordic Kidney group and the Tissue Typing group in Scandiatransplant (2017)
Scandiatransplant acceptable mismatch program (STAMP) a bridge to transplanting highly immunized patients
HLA (in press)
PubMed 28449350

Publications 2015

Thorsen T, Dahlgren US, Aandahl EM, Grzyb K, Karlsen TH, Boberg KM, Rydberg L, Naper C, Foss A, Bennet W (2015)
Liver transplantation with deceased ABO-incompatible donors is life-saving but associated with increased risk of rejection and post-transplant complications
Transpl Int, 28 (7), 800-12
PubMed 25736519

Publications 2013

Boulland LM, Naper C, Skauby MH (2013)
Presensitization revisited: pitfalls of vascular allografts in transplant candidates
Clin Kidney J, 7 (1), 65-67
PubMed 24466426

Dörje C, Midtvedt K, Holdaas H, Naper C, Strøm EH, Øyen O, Leivestad T, Aronsen T, Jenssen T, Flaa-Johnsen L, Lindahl JP, Hartmann A, Reisæter AV (2013)
Early versus late acute antibody-mediated rejection in renal transplant recipients
Transplantation, 96 (1), 79-84
PubMed 23632391

Publications 2012

Daws MR, Dai KZ, Zinöcker S, Naper C, Kveberg L, Hedrich HJ, Rolstad B, Vaage JT (2012)
Identification of an MHC class I ligand for the single member of a killer cell lectin-like receptor family, KLRH1
J Immunol, 189 (11), 5178-84
PubMed 23100519

Publications 2011

Inngjerdingen M, Kveberg L, Naper C, Vaage JT (2011)
Natural killer cell subsets in man and rodents
Tissue Antigens, 78 (2), 81-8
PubMed 21726202

Naper C, Shegarfi H, Inngjerdingen M, Rolstad B (2011)
The role of natural killer cells in the defense against Listeria monocytogenes lessons from a rat model
J Innate Immun, 3 (3), 289-97
PubMed 21430356

Shegarfi H, Dai KZ, Daws MR, Ryan JC, Vaage JT, Rolstad B, Naper C (2011)
The rat NK cell receptors Ly49s4 and Ly49i4 recognize nonclassical MHC-I molecules on Listeria monocytogenes-infected macrophages
J Leukoc Biol, 89 (4), 617-23
PubMed 21248147

Publications 2010

Kveberg L, Jiménez-Royo P, Naper C, Rolstad B, Butcher GW, Vaage JT, Inngjerdingen M (2010)
Two complementary rat NK cell subsets, Ly49s3+ and NKR-P1B+, differ in phenotypic characteristics and responsiveness to cytokines
J Leukoc Biol, 88 (1), 87-93
PubMed 20395458

Naper C, Kveberg L, Engh E, Nestvold J, Rolstad B, Vaage JT (2010)
Partial NK cell tolerance induced by radioresistant host cells in rats transplanted with MHC-mismatched bone marrow
Int Immunol, 22 (12), 973-80
PubMed 21118904

Shegarfi H, Dai KZ, Inngjerdingen M, Ryan JC, Vaage JT, Rolstad B, Naper C (2010)
The activating rat Ly49s5 receptor responds to increased levels of MHC class Ib molecules on Listeria monocytogenes-infected enteric epithelial cells
Eur J Immunol, 40 (12), 3535-43
PubMed 21108473

Shegarfi H, Naper C, Rolstad B, Inngjerdingen M (2010)
Listeria monocytogenes infection affects a subset of Ly49-expressing NK cells in the rat
PLoS One, 5 (12), e15579
PubMed 21179539

Publications 2009

Kveberg L, Dai KZ, Westgaard IH, Daws MR, Fossum S, Naper C, Vaage JT (2009)
Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding
Eur J Immunol, 39 (2), 541-51
PubMed 19130483

Shegarfi H, Sydnes K, Løvik M, Inngjerdingen M, Rolstad B, Naper C (2009)
The role of natural killer cells in resistance to the intracellular bacterium Listeria monocytogenes in rats
Scand J Immunol, 70 (3), 238-44
PubMed 19703013

Publications 2008

Reikerås O, Shegarfi H, Naper C, Reinholt FP, Rolstad B (2008)
Impact of MHC mismatch and freezing on bone graft incorporation: an experimental study in rats
J Orthop Res, 26 (7), 925-31
PubMed 18302282

Publications 2007

Bastian D, Shegarfi H, Rolstad B, Naper C, Lyngstadaas SP, Reikerås O (2007)
Investigation of lipopolysaccharide receptor expression on human monocytes after major orthopaedic surgery
Eur Surg Res, 40 (2), 239-45
PubMed 18063867

Publications 2006

Kveberg L, Bäck CJ, Dai KZ, Inngjerdingen M, Rolstad B, Ryan JC, Vaage JT, Naper C (2006)
The novel inhibitory NKR-P1C receptor and Ly49s3 identify two complementary, functionally distinct NK cell subsets in rats
J Immunol, 176 (7), 4133-40
PubMed 16547249

Kveberg L, Dai KZ, Dissen E, Ryan JC, Rolstad B, Vaage JT, Naper C (2006)
Strain-dependent expression of four structurally related rat Ly49 receptors; correlation with NK gene complex haplotype and NK alloreactivity
Immunogenetics, 58 (11), 905-16
PubMed 17028855

Publications 2005

Naper C, Dai KZ, Kveberg L, Rolstad B, Niemi EC, Vaage JT, Ryan JC (2005)
Two structurally related rat Ly49 receptors with opposing functions (Ly49 stimulatory receptor 5 and Ly49 inhibitory receptor 5) recognize nonclassical MHC class Ib-encoded target ligands
J Immunol, 174 (5), 2702-11
PubMed 15728478

Nylenna O, Flornes LM, Westgaard IH, Woon PY, Naper C, Vaage JT, Gauguier D, Ryan JC, Dissen E, Fossum S (2005)
Killer cell lectin-like receptors and the natural killer cell gene complex
Adv Exp Med Biol, 564, 23-4
PubMed 16400803

Nylenna O, Naper C, Vaage JT, Woon PY, Gauguier D, Dissen E, Ryan JC, Fossum S (2005)
The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex
Eur J Immunol, 35 (1), 261-72
PubMed 15593300

Publications 2004

Nejad S, Bryceson Y, Dissen E, Sundvold-Gjerstad V, Naper C, Rolstad B, Spurkland A, Vaage JT (2004)
cDNA cloning of a rat orthologue of SH2D2A encoding T-cell-specific adaptor protein (TSAd): expression in T and NK cells
Immunogenetics, 56 (5), 338-42
PubMed 15300336

Nestvold J, Stokland A, Naper C, Rolstad B (2004)
Phenotype and natural killer cell sensitivity of a radiation-induced acute T-cell leukaemia (Roser leukaemia) in PVG rats
Scand J Immunol, 60 (1-2), 153-8
PubMed 15238084

Publications 2002

Naper C, Hayashi S, Joly E, Butcher GW, Rolstad B, Vaage JT, Ryan JC (2002)
Ly49i2 is an inhibitory rat natural killer cell receptor for an MHC class Ia molecule (RT1-A1c)
Eur J Immunol, 32 (7), 2031-6
PubMed 12115624

Naper C, Hayashi S, Kveberg L, Niemi EC, Lanier LL, Vaage JT, Ryan JC (2002)
Ly-49s3 is a promiscuous activating rat NK cell receptor for nonclassical MHC class I-encoded target ligands
J Immunol, 169 (1), 22-30
PubMed 12077224

Naper C, Hayashi S, Løvik G, Kveberg L, Niemi EC, Rolstad B, Dissen E, Ryan JC, Vaage JT (2002)
Characterization of a novel killer cell lectin-like receptor (KLRH1) expressed by alloreactive rat NK cells
J Immunol, 168 (10), 5147-54
PubMed 11994469

Publications 2001

Løvik G, Vaage JT, Rolstad B, Naper C (2001)
The effect of in vivo depletion of NKR-P1+ or CD8+ lymphocytes on the acute rejection of allogeneic lymphocytes (ALC) in the rat
Scand J Immunol, 54 (4), 341-7
PubMed 11555400

Rolstad B, Naper C, Løvik G, Vaage JT, Ryan JC, Bäckman-Petersson E, Kirsch RD, Butcher GW (2001)
Rat natural killer cell receptor systems and recognition of MHC class I molecules
Immunol Rev, 181, 149-57
PubMed 11513136

Ryan JC, Naper C, Hayashi S, Daws MR (2001)
Physiologic functions of activating natural killer (NK) complex-encoded receptors on NK cells
Immunol Rev, 181, 126-37
PubMed 11513134

Publications 1999

Nakamura MC, Naper C, Niemi EC, Spusta SC, Rolstad B, Butcher GW, Seaman WE, Ryan JC (1999)
Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor
J Immunol, 163 (9), 4694-700
PubMed 10528166

Naper C, Ryan JC, Kirsch R, Butcher GW, Rolstad B, Vaage JT (1999)
Genes in two major histocompatibility complex class I regions control selection, phenotype, and function of a rat Ly-49 natural killer cell subset
Eur J Immunol, 29 (6), 2046-53
PubMed 10382768

Publications 1998

Naper C, Ryan JC, Nakamura MC, Lambracht D, Rolstad B, Vaage JT (1998)
Identification of an inhibitory MHC receptor on alloreactive rat natural killer cells
J Immunol, 160 (1), 219-24
PubMed 9551974

Publications 1997

Knudsen E, Seierstad T, Vaage JT, Naper C, Benestad HB, Rolstad B, Maghazachi AA (1997)
Cloning, functional activities and in vivo tissue distribution of rat NKR-P1+ TCR alpha beta + cells
Int Immunol, 9 (7), 1043-51
PubMed 9237113

Rolstad B, Vaage JT, Naper C, Lambracht D, Wonigeit K, Joly E, Butcher GW (1997)
Positive and negative MHC class I recognition by rat NK cells
Immunol Rev, 155, 91-104
PubMed 9059885

Torgersen KM, Salcedo M, Vaage JT, Naper C, Rolstad B, Ljunggren HG, Höglund P (1997)
Major histocompatibility complex class I-independent killing of xenogeneic targets by rat allospecific natural killer cells
Transplantation, 63 (1), 119-23
PubMed 9000672

Publications 1996

Maghazachi AA, Al-Aoukaty A, Naper C, Torgersen KM, Rolstad B (1996)
Preferential involvement of Go and Gz proteins in mediating rat natural killer cell lysis of allogeneic and tumor target cells
J Immunol, 157 (12), 5308-14
PubMed 8955177

Naper C, Rolstad B, Wonigeit K, Butcher GW, Vaage JT (1996)
Genes in two MHC class I regions control recognition of a single rat NK cell allodeterminant
Int Immunol, 8 (11), 1779-85
PubMed 8943573

Publications 1995

Løvik G, Vaage JT, Naper C, Benestad HB, Rolstad B (1995)
Recruitment of alloreactive natural killer cells to the rat peritoneum by a transfected cell line secreting rat recombinant interleukin-2
J Immunol Methods, 179 (1), 59-69
PubMed 7868925

Naper C, Vaage JT, Lambracht D, Løvik G, Butcher GW, Wonigeit K, Rolstad B (1995)
Alloreactive natural killer cells in the rat: complex genetics of major histocompatibility complex control
Eur J Immunol, 25 (5), 1249-56
PubMed 7774627

Publications 1994

Vaage JT, Naper C, Løvik G, Lambracht D, Rehm A, Hedrich HJ, Wonigeit K, Rolstad B (1994)
Control of rat natural killer cell-mediated allorecognition by a major histocompatibility complex region encoding nonclassical class I antigens
J Exp Med, 180 (2), 641-51
PubMed 8046337

Publications 1993

Løvik G, Vaage JT, Naper C, Rolstad B (1993)
Natural killer cell alloreactivity in the rat: I. Potent in vivo recruitment of rat natural killer cells with an interleukin-2-producing cell line in intraperitoneal diffusion chambers
Transplant Proc, 25 (5), 2800-1
PubMed 8212239

Vaage JT, Løvik G, Naper C, Hedrich HJ, Wonigeit K, Rolstad B (1993)
Natural killer cell alloreactivity in the rat: II. Predominant role of the RT1.C region in determining target cell susceptibility and specificity
Transplant Proc, 25 (5), 2802-3
PubMed 8212240