Kirsten Sandvig
Position: Group leader, Professor
Phone: +47 22 78 18 28
Email:
 

Author network for Kirsten Sandvig by COREMINE medical


Publications 2017

Ailte I, Lingelem AB, Kvalvaag AS, Kavaliauskiene S, Brech A, Koster G, Dommersnes PG, Bergan J, Skotland T, Sandvig K (2017)
Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Traffic, 18 (3), 176-191
PubMed 28067430

Hardes K, Ivanova T, Thaa B, McInerney GM, Klokk TI, Sandvig K, Künzel S, Lindberg I, Steinmetzer T (2017)
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin
ChemMedChem, 12 (8), 613-620
PubMed 28334511

Kavaliauskiene S, Dyve Lingelem AB, Skotland T, Sandvig K (2017)
Protection against Shiga Toxins
Toxins (Basel), 9 (2)
PubMed 28165371

Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K (2017)
Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis
PLoS One, 12 (1), e0170716
PubMed 28114329

Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K (2017)
Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network
Exp Cell Res, 357 (1), 67-78
PubMed 28450044

Skotland T, Sandvig K, Llorente A (2017)
Lipids in exosomes: Current knowledge and the way forward
Prog Lipid Res, 66, 30-41
PubMed 28342835

Vestad B, Llorente A, Neurauter A, Phuyal S, Kierulf B, Kierulf P, Skotland T, Sandvig K, Haug KBF, Øvstebø R (2017)
Size and concentration analyses of extracellular vesicles by nanoparticle tracking analysis: a variation study
J Extracell Vesicles, 6 (1), 1344087
PubMed 28804597

Publications 2016

Ailte I, Lingelem AB, Kavaliauskiene S, Bergan J, Kvalvaag AS, Myrann AG, Skotland T, Sandvig K (2016)
Addition of lysophospholipids with large head groups to cells inhibits Shiga toxin binding
Sci Rep, 6, 30336
PubMed 27458147

Asp N, Kvalvaag A, Sandvig K, Pust S (2016)
Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins
Oncotarget, 7 (18), 25443-60
PubMed 27029001

Herrera C, Klokk TI, Cole R, Sandvig K, Mantis NJ (2016)
A Bispecific Antibody Promotes Aggregation of Ricin Toxin on Cell Surfaces and Alters Dynamics of Toxin Internalization and Trafficking
PLoS One, 11 (6), e0156893
PubMed 27300140

Hessvik NP, Øverbye A, Brech A, Torgersen ML, Jakobsen IS, Sandvig K, Llorente A (2016)
PIKfyve inhibition increases exosome release and induces secretory autophagy
Cell Mol Life Sci, 73 (24), 4717-4737
PubMed 27438886

Kavaliauskiene S, Torgersen ML, Lingelem AB, Klokk TI, Lintonen T, Simolin H, Ekroos K, Skotland T, Sandvig K (2016)
Cellular effects of fluorodeoxyglucose: Global changes in the lipidome and alteration in intracellular transport
Oncotarget, 7 (48), 79885-79900
PubMed 27829218

Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2016)
Data including GROMACS input files for atomistic molecular dynamics simulations of mixed, asymmetric bilayers including molecular topologies, equilibrated structures, and force field for lipids compatible with OPLS-AA parameters
Data Brief, 7, 1171-1174
PubMed 27761499

Skotland T, Ekroos K, Kauhanen D, Simolin H, Seierstad T, Berge V, Sandvig K, Llorente A (2016)
Molecular lipid species in urinary exosomes as potential prostate cancer biomarkers
Eur J Cancer, 70, 122-132
PubMed 27914242

Skotland T, Ekroos K, Kavaliauskiene S, Bergan J, Kauhanen D, Lintonen T, Sandvig K (2016)
Determining the Turnover of Glycosphingolipid Species by Stable-Isotope Tracer Lipidomics
J Mol Biol, 428 (24 Pt A), 4856-4866
PubMed 27363608

Torgersen ML, Klokk TI, Kavaliauskiene S, Klose C, Simons K, Skotland T, Sandvig K (2016)
The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
Oncotarget, 7 (52), 86871-86888
PubMed 27894086

Wang L, Skotland T, Berge V, Sandvig K, Llorente A (2016)
Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation
Eur J Pharm Sci, 98, 80-85
PubMed 27664330

Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ (2016)
Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport
Sci Rep, 6, 22721
PubMed 26949061

Publications 2015

Dyve Lingelem AB, Hjelseth IA, Simm R, Torgersen ML, Sandvig K (2015)
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells
PLoS One, 10 (5), e0129214
PubMed 26017782

Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T (2015)
Novel Furin Inhibitors with Potent Anti-infectious Activity
ChemMedChem, 10 (7), 1218-31
PubMed 25974265

Kavaliauskiene S, Skotland T, Sylvänne T, Simolin H, Klokk TI, Torgersen ML, Lingelem AB, Simm R, Ekroos K, Sandvig K (2015)
Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids
Biochem J, 470 (1), 23-37
PubMed 26251444

Klokk TI, Kavaliauskiene S, Sandvig K (2015)
Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic
Cell Mol Life Sci, 73 (6), 1301-16
PubMed 26407609

Kymre L, Simm R, Skotland T, Sandvig K (2015)
Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells
Pathog Dis, 73 (9), ftv083
PubMed 26443836

Róg T, Orłowski A, Llorente A, Skotland T, Sylvänne T, Kauhanen D, Ekroos K, Sandvig K, Vattulainen I (2015)
Interdigitation of long-chain sphingomyelin induces coupling of membrane leaflets in a cholesterol dependent manner
Biochim Biophys Acta, 1858 (2), 281-8
PubMed 26654782

Skotland T, Iversen TG, Torgersen ML, Sandvig K (2015)
Cell-penetrating peptides: possibilities and challenges for drug delivery in vitro and in vivo
Molecules, 20 (7), 13313-23
PubMed 26205056

Słomińska-Wojewódzka M, Sandvig K (2015)
The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation
Molecules, 20 (6), 9816-46
PubMed 26023941

Sokołowska I, Piłka ES, Sandvig K, Węgrzyn G, Słomińska-Wojewódzka M (2015)
Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells
BMC Cell Biol, 16, 1
PubMed 25655076

Øverbye A, Skotland T, Koehler CJ, Thiede B, Seierstad T, Berge V, Sandvig K, Llorente A (2015)
Identification of prostate cancer biomarkers in urinary exosomes
Oncotarget, 6 (30), 30357-76
PubMed 26196085

Publications 2014

Asp N, Pust S, Sandvig K (2014)
Flotillin depletion affects ErbB protein levels in different human breast cancer cells
Biochim Biophys Acta, 1843 (9), 1987-96
PubMed 24747692

Bergan J, Skotland T, Lingelem AB, Simm R, Spilsberg B, Lindbäck T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2014)
The ether lipid precursor hexadecylglycerol protects against Shiga toxins
Cell Mol Life Sci, 71 (21), 4285-300
PubMed 24740796

Cordara G, Winter HC, Goldstein IJ, Krengel U, Sandvig K (2014)
The fungal chimerolectin MOA inhibits protein and DNA synthesis in NIH/3T3 cells and may induce BAX-mediated apoptosis
Biochem Biophys Res Commun, 447 (4), 586-9
PubMed 24747075

Holland P, Torgersen ML, Sandvig K, Simonsen A (2014)
LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis
Traffic, 15 (12), 1390-405
PubMed 25216107

Kvalvaag AS, Pust S, Sandvig K (2014)
Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport
Commun Integr Biol, 7 (1), e28129
PubMed 24778763

Phuyal S, Hessvik NP, Skotland T, Sandvig K, Llorente A (2014)
Regulation of exosome release by glycosphingolipids and flotillins
FEBS J, 281 (9), 2214-27
PubMed 24605801

Phuyal S, Skotland T, Hessvik NP, Simolin H, Øverbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A (2014)
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
J Biol Chem, 290 (7), 4225-37
PubMed 25519911

Sandvig K, Bergan J, Kavaliauskiene S, Skotland T (2014)
Lipid requirements for entry of protein toxins into cells
Prog Lipid Res, 54, 1-13
PubMed 24462587

Skotland T, Iversen TG, Sandvig K (2014)
Development of nanoparticles for clinical use
Nanomedicine (Lond), 9 (9), 1295-9
PubMed 25204821

Słomińska-Wojewódzka M, Pawlik A, Sokołowska I, Antoniewicz J, Węgrzyn G, Sandvig K (2014)
The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol
Biochem J, 457 (3), 485-96
PubMed 24200403

Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ (2014)
Antibody-mediated inhibition of ricin toxin retrograde transport
MBio, 5 (2), e00995
PubMed 24713323

Publications 2013

Bergan J, Skotland T, Sylvänne T, Simolin H, Ekroos K, Sandvig K (2013)
The ether lipid precursor hexadecylglycerol causes major changes in the lipidome of HEp-2 cells
PLoS One, 8 (9), e75904
PubMed 24098742

Gregers TF, Skånland SS, Wälchli S, Bakke O, Sandvig K (2013)
BiP negatively affects ricin transport
Toxins (Basel), 5 (5), 969-82
PubMed 23666197

Hessvik NP, Sandvig K, Llorente A (2013)
Exosomal miRNAs as Biomarkers for Prostate Cancer
Front Genet, 4, 36
PubMed 23519132

Kavaliauskiene S, Nymark CM, Bergan J, Simm R, Sylvänne T, Simolin H, Ekroos K, Skotland T, Sandvig K (2013)
Cell density-induced changes in lipid composition and intracellular trafficking
Cell Mol Life Sci, 71 (6), 1097-116
PubMed 23921715

Kvalvaag AS, Pust S, Sundet KI, Engedal N, Simm R, Sandvig K (2013)
The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport
Traffic, 14 (7), 839-52
PubMed 23593995

Llorente A, Skotland T, Sylvänne T, Kauhanen D, Róg T, Orłowski A, Vattulainen I, Ekroos K, Sandvig K (2013)
Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
Biochim Biophys Acta, 1831 (7), 1302-9
PubMed 24046871

Sandvig K, Skotland T, van Deurs B, Klokk TI (2013)
Retrograde transport of protein toxins through the Golgi apparatus
Histochem Cell Biol, 140 (3), 317-26
PubMed 23765164

Publications 2012

Becker GL, Lu Y, Hardes K, Strehlow B, Levesque C, Lindberg I, Sandvig K, Bakowsky U, Day R, Garten W, Steinmetzer T (2012)
Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
J Biol Chem, 287 (26), 21992-2003
PubMed 22539349

Bergan J, Dyve Lingelem AB, Simm R, Skotland T, Sandvig K (2012)
Shiga toxins
Toxicon, 60 (6), 1085-107
PubMed 22960449

Hessvik NP, Phuyal S, Brech A, Sandvig K, Llorente A (2012)
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
Biochim Biophys Acta, 1819 (11-12), 1154-63
PubMed 22982408

Ilina P, Hyvonen Z, Saura M, Sandvig K, Yliperttula M, Ruponen M (2012)
Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems
J Control Release, 163 (3), 385-95
PubMed 23041276

Iversen TG, Frerker N, Sandvig K (2012)
Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism
J Nanobiotechnology, 10, 33
PubMed 22849338

Pust S, Klokk TI, Musa N, Jenstad M, Risberg B, Erikstein B, Tcatchoff L, Liestøl K, Danielsen HE, van Deurs B, Sandvig K (2012)
Flotillins as regulators of ErbB2 levels in breast cancer
Oncogene, 32 (29), 3443-51
PubMed 22869152

Sandvig K, Llorente A (2012)
Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
Mol Cell Proteomics, 11 (7), M111.012914
PubMed 22457534

Tcatchoff L, Andersson S, Utskarpen A, Klokk TI, Skånland SS, Pust S, Gerke V, Sandvig K (2012)
Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
PLoS One, 7 (7), e40429
PubMed 22792315

Publications 2011

Cordara G, Egge-Jacobsen W, Johansen HT, Winter HC, Goldstein IJ, Sandvig K, Krengel U (2011)
Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity
Biochem Biophys Res Commun, 408 (3), 405-10
PubMed 21513701

Dang H, Klokk TI, Schaheen B, McLaughlin BM, Thomas AJ, Durns TA, Bitler BG, Sandvig K, Fares H (2011)
Derlin-dependent retrograde transport from endosomes to the Golgi apparatus
Traffic, 12 (10), 1417-31
PubMed 21722281

Dyve Lingelem AB, Bergan J, Sandvig K (2011)
Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
Traffic, 13 (3), 443-54
PubMed 22132807

Engedal N, Skotland T, Torgersen ML, Sandvig K (2011)
Shiga toxin and its use in targeted cancer therapy and imaging
Microb Biotechnol, 4 (1), 32-46
PubMed 21255370

Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J (2011)
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
PLoS One, 6 (7), e21708
PubMed 21779335

Iversen TG, Skotland T, Sandvig K (2011)
Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
Nano Today, 6 (2), 176-185

Klokk TI, Lingelem AB, Myrann AG, Sandvig K (2011)
Role of phospholipase A(2) in retrograde transport of ricin
Toxins (Basel), 3 (9), 1203-19
PubMed 22069763

Sandvig K, Pust S, Skotland T, van Deurs B (2011)
Clathrin-independent endocytosis: mechanisms and function
Curr Opin Cell Biol, 23 (4), 413-20
PubMed 21466956

Skotland T, Iversen TG, Sandvig K (2011)
Comment on "short ligands affect modes of QD uptake and elimination in human cells"
ACS Nano, 5 (10), 7690; author reply 7691-2
PubMed 22023400

Sokołowska I, Wälchli S, Węgrzyn G, Sandvig K, Słomińska-Wojewódzka M (2011)
A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
Biochem J, 436 (2), 371-85
PubMed 21388347

Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2011)
Protein C mutation (A267T) results in ER retention and unfolded protein response activation
PLoS One, 6 (8), e24009
PubMed 21901152

Publications 2010

Pust S, Barth H, Sandvig K (2010)
Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
Cell Microbiol, 12 (12), 1809-20
PubMed 20690924

Pust S, Dyve AB, Torgersen ML, van Deurs B, Sandvig K (2010)
Interplay between toxin transport and flotillin localization
PLoS One, 5 (1), e8844
PubMed 20107503

Sandvig K, Torgersen ML, Engedal N, Skotland T, Iversen TG (2010)
Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
FEBS Lett, 584 (12), 2626-34
PubMed 20385131

Skotland T, Iversen TG, Sandvig K (2010)
New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
Nanomedicine, 6 (6), 730-7
PubMed 20570639

Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2010)
Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
BMC Cell Biol, 11, 67
PubMed 20815936

Torgersen ML, Engedal N, Bergan J, Sandvig K (2010)
The Intracellular Journey of Shiga Toxins
The Open Toxinology Journal, 3, 3-12
PublikaID 24

Torgersen ML, Engedal N, Pedersen AM, Husebye H, Espevik T, Sandvig K (2010)
Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
FEMS Immunol Med Microbiol, 61 (1), 63-75
PubMed 21054580

Utskarpen A, Massol R, van Deurs B, Lauvrak SU, Kirchhausen T, Sandvig K (2010)
Shiga toxin increases formation of clathrin-coated pits through Syk kinase
PLoS One, 5 (7), e10944
PubMed 20668539

Publications 2009

Dyve AB, Bergan J, Utskarpen A, Sandvig K (2009)
Sorting nexin 8 regulates endosome-to-Golgi transport
Biochem Biophys Res Commun, 390 (1), 109-14
PubMed 19782049

Døving KB, Sandvig K, Kasumyan A (2009)
Ligand-specific induction of endocytosis in taste receptor cells
J Exp Biol, 212 (Pt 1), 42-9
PubMed 19088209

Iversen TG, Frerker N, Sandvig K (2009)
Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
PublikaID 29

Iversen TG, Frerker N, Sandvig K (2009)
Quantum dot bioconjugates: Uptake into cells and induction of changes in normal cellular transport
P SOC PHOTO-OPT INS, 7189, 71890T

Raa H, Grimmer S, Schwudke D, Bergan J, Wälchli S, Skotland T, Shevchenko A, Sandvig K (2009)
Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
Traffic, 10 (7), 868-82
PubMed 19453975

Sandvig K, Bergan J, Dyve AB, Skotland T, Torgersen ML (2009)
Endocytosis and retrograde transport of Shiga toxin
Toxicon, 56 (7), 1181-5
PubMed 19951719

Skånland SS, Wälchli S, Brech A, Sandvig K (2009)
SNX4 in complex with clathrin and dynein: implications for endosome movement
PLoS One, 4 (6), e5935
PubMed 19529763

Skånland SS, Wälchli S, Sandvig K (2009)
β-arrestins attenuate p38-mediated endosome to Golgi transport
Cell Microbiol, 11 (5), 796-807
PubMed 19159388

Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K (2009)
Characterization of clathrin and Syk interaction upon Shiga toxin binding
Cell Signal, 21 (7), 1161-8
PubMed 19289168

Publications 2008

Sandvig K, Torgersen ML, Raa HA, van Deurs B (2008)
Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
Histochem Cell Biol, 129 (3), 267-76
PubMed 18193449

Sandvig K, van Deurs B (2008)
Cell biology: Viruses in camouflage
Nature, 453 (7194), 466-7
PubMed 18497813

Tekle C, Deurs Bv, Sandvig K, Iversen TG (2008)
Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
Nano Lett, 8 (7), 1858-65
PubMed 18570482

Publications 2007

Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH (2007)
The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
Exp Cell Res, 313 (8), 1696-709
PubMed 17382318

Kurmanova A, Llorente A, Polesskaya A, Garred O, Olsnes S, Kozlov J, Sandvig K (2007)
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
PubMed 17407762

Llorente A, van Deurs B, Sandvig K (2007)
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
Eur J Cell Biol, 86 (7), 405-15
PubMed 17601634

Martín-Acebes MA, González-Magaldi M, Sandvig K, Sobrino F, Armas-Portela R (2007)
Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
Virology, 369 (1), 105-18
PubMed 17714753

Skånland SS, Wälchli S, Utskarpen A, Wandinger-Ness A, Sandvig K (2007)
Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
Traffic, 8 (3), 297-309
PubMed 17319803

Spilsberg B, Llorente A, Sandvig K (2007)
Polyunsaturated fatty acids regulate Shiga toxin transport
Biochem Biophys Res Commun, 364 (2), 283-8
PubMed 17942073

Torgersen ML, Wälchli S, Grimmer S, Skånland SS, Sandvig K (2007)
Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
J Biol Chem, 282 (22), 16317-28
PubMed 17403690

Utskarpen A, Slagsvold HH, Dyve AB, Skånland SS, Sandvig K (2007)
SNX1 and SNX2 mediate retrograde transport of Shiga toxin
Biochem Biophys Res Commun, 358 (2), 566-70
PubMed 17498660

Wälchli S, Skånland SS, Gregers TF, Lauvrak SU, Torgersen ML, Ying M, Kuroda S, Maturana A, Sandvig K (2007)
The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking
Mol Biol Cell, 19 (1), 95-104
PubMed 17959827

Publications 2006

Grimmer S, Spilsberg B, Hanada K, Sandvig K (2006)
Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
Traffic, 7 (9), 1243-53
PubMed 16919154

Slominska-Wojewodzka M, Gregers TF, Wälchli S, Sandvig K (2006)
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
Mol Biol Cell, 17 (4), 1664-75
PubMed 16452630

Utskarpen A, Slagsvold HH, Iversen TG, Wälchli S, Sandvig K (2006)
Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
Traffic, 7 (6), 663-72
PubMed 16683916

Publications 2005

Grimmer S, Ying M, Wälchli S, van Deurs B, Sandvig K (2005)
Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
Traffic, 6 (2), 144-56
PubMed 15634214

Guerra L, Teter K, Lilley BN, Stenerlöw B, Holmes RK, Ploegh HL, Sandvig K, Thelestam M, Frisan T (2005)
Cellular internalization of cytolethal distending toxin: a new end to a known pathway
Cell Microbiol, 7 (7), 921-34
PubMed 15953025

Hommelgaard AM, Roepstorff K, Vilhardt F, Torgersen ML, Sandvig K, van Deurs B (2005)
Caveolae: stable membrane domains with a potential for internalization
Traffic, 6 (9), 720-4
PubMed 16101676

Lauvrak SU, Wälchli S, Iversen TG, Slagsvold HH, Torgersen ML, Spilsberg B, Sandvig K (2005)
Shiga toxin regulates its entry in a Syk-dependent manner
Mol Biol Cell, 17 (3), 1096-109
PubMed 16371508

Sandvig K, van Deurs B (2005)
Delivery into cells: lessons learned from plant and bacterial toxins
Gene Ther, 12 (11), 865-72
PubMed 15815697

Spilsberg B, Hanada K, Sandvig K (2005)
Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
Biochem Biophys Res Commun, 329 (2), 465-73
PubMed 15737610

Spilsberg B, Sandvig K, Wälchli S (2005)
Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
Toxicon, 46 (8), 900-6
PubMed 16260019

Torgersen ML, Lauvrak SU, Sandvig K (2005)
The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
FEBS J, 272 (16), 4103-13
PubMed 16098193

Publications 2004

Lauvrak SU, Torgersen ML, Sandvig K (2004)
Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
J Cell Sci, 117 (Pt 11), 2321-31
PubMed 15126632

Sandvig K, Spilsberg B, Lauvrak SU, Torgersen ML, Iversen TG, van Deurs B (2004)
Pathways followed by protein toxins into cells
Int J Med Microbiol, 293 (7-8), 483-90
PubMed 15149022

Publications 2003

Iversen TG, Skretting G, van Deurs B, Sandvig K (2003)
Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
Proc Natl Acad Sci U S A, 100 (9), 5175-80
PubMed 12682302

Llorente A, Lauvrak SU, van Deurs B, Sandvig K (2003)
Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
J Biol Chem, 278 (37), 35850-5
PubMed 12847103

Sandvig K, van Deurs B (2003)
Cholera toxin internalization and intoxication - Reply
J. Cell Sci., 116 (3), 432-433

Spillsberg B, van Meer G, Sandvig K (2003)
Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-552

Spilsberg B, Van Meer G, Sandvig K (2003)
Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-52
PubMed 12839497

van Deurs B, Roepstorff K, Hommelgaard AM, Sandvig K (2003)
Caveolae: anchored, multifunctional platforms in the lipid ocean
Trends Cell Biol, 13 (2), 92-100
PubMed 12559760

van Deurs B, Roepstorff K, Hommelgaard AM, Sandvig K (2003)
Caveolae: anchored, multifunctional platforms in the lipid ocean
Trends Cell Biol., 13 (2), PII S0962-8924(02)00039-9-100

Ying M, Grimmer S, Iversen TG, Van Deurs B, Sandvig K (2003)
Cholesterol loading induces a block in the exit of VSVG from the TGN
Traffic, 4 (11), 772-84
PubMed 14617359

Publications 2002

Birkeli KA, Llorente A, Torgersen ML, Keryer G, Taskén K, Sandvig K (2002)
Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
J Biol Chem, 278 (3), 1991-7
PubMed 12419802

Grimmer S, van Deurs B, Sandvig K (2002)
Membrane ruffling and macropinocytosis in A431 cells require cholesterol
J Cell Sci, 115 (Pt 14), 2953-62
PubMed 12082155

Lauvrak SU, Llorente A, Iversen TG, Sandvig K (2002)
Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
J Cell Sci, 115 (Pt 17), 3449-56
PubMed 12154075

Roepstorff K, Thomsen P, Sandvig K, van Deurs B (2002)
Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
J Biol Chem, 277 (21), 18954-60
PubMed 11886870

Sandvig K, van Deurs B (2002)
Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
FEBS Lett, 529 (1), 49-53
PubMed 12354612

Sandvig K, van Deurs B (2002)
Membrane traffic exploited by protein toxins
Annu Rev Cell Dev Biol, 18, 1-24
PubMed 12142266

Sandvig K, van Deurs B (2002)
Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
FEBS Lett., 529 (1), PII S0014-5793(02)03182-4-53

Tse SM, Furuya W, Gold E, Schreiber AD, Sandvig K, Inman RD, Grinstein S (2002)
Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis
J Biol Chem, 278 (5), 3331-8
PubMed 12424246

Publications 2001

Garred Ø, Rodal SK, van Deurs B, Sandvig K (2001)
Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
Traffic, 2 (1), 26-36
PubMed 11208166

Iversen TG, Skretting G, Llorente A, Nicoziani P, van Deurs B, Sandvig K (2001)
Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
Mol Biol Cell, 12 (7), 2099-107
PubMed 11452006

Llorente A, Prydz K, Sprangers M, Skretting G, Kolset SO, Sandvig K (2001)
Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
J Cell Sci, 114 (Pt 2), 335-43
PubMed 11148135

Sandvig K (2001)
Shiga toxins
Toxicon, 39 (11), 1629-35
PubMed 11595626

Sandvig K, Grimmer S, Lauvrak SU, Torgersen ML, Skretting G, van Deurs B, Iversen TG (2001)
Pathways followed by ricin and Shiga toxin into cells
Histochem Cell Biol, 117 (2), 131-41
PubMed 11935289

Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2001)
In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
Int J Cancer, 92 (5), 761-6
PubMed 11340584

Torgersen ML, Skretting G, van Deurs B, Sandvig K (2001)
Internalization of cholera toxin by different endocytic mechanisms
J Cell Sci, 114 (Pt 20), 3737-47
PubMed 11707525

Publications 2000

Falnes PO, Ariansen S, Sandvig K, Olsnes S (2000)
Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
J Biol Chem, 275 (6), 4363-8
PubMed 10660606

Falnes PO, Sandvig K (2000)
Penetration of protein toxins into cells
Curr Opin Cell Biol, 12 (4), 407-13
PubMed 10873820

Grimmer S, Iversen TG, van Deurs B, Sandvig K (2000)
Endosome to Golgi transport of ricin is regulated by cholesterol
Mol Biol Cell, 11 (12), 4205-16
PubMed 11102518

Llorente A, van Deurs B, Garred O, Eker P, Sandvig K (2000)
Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
J Cell Sci, 113 ( Pt 7), 1213-21
PubMed 10704372

Nicoziani P, Vilhardt F, Llorente A, Hilout L, Courtoy PJ, Sandvig K, van Deurs B (2000)
Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
Mol Biol Cell, 11 (2), 481-95
PubMed 10679008

Sandvig K, Grimmer S, Iversen TG, Rodal K, Torgersen ML, Nicoziani P, van Deurs B (2000)
Ricin transport into cells: studies of endocytosis and intracellular transport
Int J Med Microbiol, 290 (4-5), 415-20
PubMed 11111920

Sandvig K, Llorente A, Rodal SK, Eker P, Garred O, Stahlhut M, van Deurs B (2000)
Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
Eur J Cell Biol, 79 (7), 447-57
PubMed 10961444

Sandvig K, van Deurs B (2000)
Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
EMBO J, 19 (22), 5943-50
PubMed 11080141

Selbo PK, Sandvig K, Kirveliene V, Berg K (2000)
Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
Biochim Biophys Acta, 1475 (3), 307-13
PubMed 10913830

Selbo PK, Sivam G, Fodstad O, Sandvig K, Berg K (2000)
Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
Int J Cancer, 87 (6), 853-9
PubMed 10956397

Stahlhut M, Sandvig K, van Deurs B (2000)
Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer
Exp Cell Res, 261 (1), 111-8
PubMed 11082281

Publications 1999

Berg K, Selbo PK, Prasmickaite L, Tjelle TE, Sandvig K, Moan J, Gaudernack G, Fodstad O, Kjølsrud S, Anholt H, Rodal GH, Rodal SK, Høgset A (1999)
Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
Cancer Res, 59 (6), 1180-3
PubMed 10096543

Rodal SK, Skretting G, Garred O, Vilhardt F, van Deurs B, Sandvig K (1999)
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
Mol Biol Cell, 10 (4), 961-74
PubMed 10198050

Sandvig K, van Deurs B (1999)
Endocytosis and intracellular transport of ricin: recent discoveries
FEBS Lett, 452 (1-2), 67-70
PubMed 10376680

Skretting G, Torgersen ML, van Deurs B, Sandvig K (1999)
Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
J Cell Sci, 112 ( Pt 22), 3899-909
PubMed 10547351

Vilhardt F, Nielsen M, Sandvig K, van Deurs B (1999)
Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells
Mol Biol Cell, 10 (1), 179-95
PubMed 9880335

Publications 1998

Drolsum L, Haaskjold E, Sandvig K (1998)
Phacoemulsification in eyes with pseudoexfoliation
J Cataract Refract Surg, 24 (6), 787-92
PubMed 9642589

Llorente A, Rapak A, Schmid SL, van Deurs B, Sandvig K (1998)
Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
J Cell Biol, 140 (3), 553-63
PubMed 9456316

Llorente A, van Deurs B, Sandvig K (1998)
Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
FEBS Lett, 431 (2), 200-4
PubMed 9708902

Vogel U, Sandvig K, van Deurs B (1998)
Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
J Cell Sci, 111 ( Pt 6), 825-32
PubMed 9472010

Publications 1997

Garred O, Dubinina E, Polesskaya A, Olsnes S, Kozlov J, Sandvig K (1997)
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
PubMed 9111051

Sandvig K, Garred O, van Deurs B (1997)
Intracellular transport and processing of protein toxins produced by enteric bacteria
Adv Exp Med Biol, 412, 225-32
PubMed 9192018

Publications 1996

Allen ED, Burton RL, Webber SK, Haaskjold E, Sandvig K, Jyrkkiö H, Leite E, Nyström A, Wollensak J (1996)
Comparison of a diffractive bifocal and a monofocal intraocular lens
J Cataract Refract Surg, 22 (4), 446-51
PubMed 8733848

Llorente A, Garred O, Holm PK, Eker P, Jacobsen J, van Deurs B, Sandvig K (1996)
Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
Exp Cell Res, 227 (2), 298-308
PubMed 8831568

Sandvig K, Garred O, van Deurs B (1996)
Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
Proc Natl Acad Sci U S A, 93 (22), 12339-43
PubMed 8901582

Sandvig K, Garred O, van Helvoort A, van Meer G, van Deurs B (1996)
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
Mol Biol Cell, 7 (9), 1391-404
PubMed 8885234

Sandvig K, van Deurs B (1996)
Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
Physiol Rev, 76 (4), 949-66
PubMed 8874490

van Deurs B, Holm PK, Sandvig K (1996)
Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells
Eur J Cell Biol, 69 (4), 343-50
PubMed 8741216

van Deurs B, von Bũlow F, Vilhardt F, Holm PK, Sandvig K (1996)
Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane
J Cell Sci, 109 ( Pt 7), 1655-65
PubMed 8832388

Publications 1995

ERIKSEN S, SAND O, LANZREIN M, SANDVIG K, OLSNES S (1995)
CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168

Garred O, Dubinina E, Holm PK, Olsnes S, van Deurs B, Kozlov JV, Sandvig K (1995)
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
PubMed 7737376

Garred O, van Deurs B, Sandvig K (1995)
Furin-induced cleavage and activation of Shiga toxin
J Biol Chem, 270 (18), 10817-21
PubMed 7738018

Holm PK, Eker P, Sandvig K, van Deurs B (1995)
Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
Exp Cell Res, 217 (1), 157-68
PubMed 7867714

Lanzrein M, Garred O, Olsnes S, Sandvig K (1995)
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1), 285-9
PubMed 7646457

van Deurs B, Holm PK, Kayser L, Sandvig K (1995)
Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
Eur J Cell Biol, 66 (4), 309-23
PubMed 7544728

Publications 1994

Eker P, Holm PK, van Deurs B, Sandvig K (1994)
Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP
J Biol Chem, 269 (28), 18607-15
PubMed 8034609

Eriksen S, Olsnes S, Sandvig K, Sand O (1994)
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
EMBO J, 13 (19), 4433-9
PubMed 7523112

Madshus IH, Wiedlocha A, Sandvig K (1994)
Intermediates in translocation of diphtheria toxin across the plasma membrane
J Biol Chem, 269 (6), 4648-52
PubMed 7508447

SANDVIG K, GARRED O, HOLM PK, VANDEURS B (1994)
ENTRY OF SHIGA TOXIN INTO CELLS
INT CONGR SER, 1072, 139-146

Sandvig K, Ryd M, Garred O, Schweda E, Holm PK, van Deurs B (1994)
Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
J Cell Biol, 126 (1), 53-64
PubMed 8027186

Sandvig K, van Deurs B (1994)
Endocytosis and intracellular sorting of ricin and Shiga toxin
FEBS Lett, 346 (1), 99-102
PubMed 8206167

Sandvig K, van Deurs B (1994)
Endocytosis without clathrin
Trends Cell Biol, 4 (8), 275-7
PubMed 14731589

SANDVIG K, VANDEURS B (1994)
ENTRY OF SHIGA TOXIN INTO CELLS
ZBL BAKT S, 24, 365-374

Wiedłocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S (1994)
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
PubMed 7511061

Publications 1993

Hansen SH, Sandvig K, van Deurs B (1993)
Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
J Cell Biol, 123 (1), 89-97
PubMed 8408209

Hansen SH, Sandvig K, van Deurs B (1993)
Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification
J Cell Biol, 121 (1), 61-72
PubMed 8458873

Holm PK, Hansen SH, Sandvig K, van Deurs B (1993)
Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment
Eur J Cell Biol, 62 (2), 362-71
PubMed 7925492

Ludt J, Sandvig K, Olsnes S (1993)
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
PubMed 8411117

Melby EL, Jacobsen J, Olsnes S, Sandvig K (1993)
Entry of protein toxins in polarized epithelial cells
Cancer Res, 53 (8), 1755-60
PubMed 8467493

Olsnes S, van Deurs B, Sandvig K (1993)
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
PubMed 8392658

Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, Van Deurs B (1993)
Entry of Shiga toxin into cells
Zentralbl Bakteriol, 278 (2-3), 296-305
PubMed 8347933

Sandvig K, Garred O, Holm PK, van Deurs B (1993)
Endocytosis and intracellular transport of protein toxins
Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
PubMed 8224494

van Deurs B, Holm PK, Kayser L, Sandvig K, Hansen SH (1993)
Multivesicular bodies in HEp-2 cells are maturing endosomes
Eur J Cell Biol, 61 (2), 208-24
PubMed 8223712

van Deurs B, Holm PK, Sandvig K, Hansen SH (1993)
Are caveolae involved in clathrin-independent endocytosis?
Trends Cell Biol, 3 (8), 249-51
PubMed 14731741

Publications 1992

Falnes PO, Madshus IH, Sandvig K, Olsnes S (1992)
Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
J Biol Chem, 267 (17), 12284-90
PubMed 1376320

Hansen SH, Sandvig K, van Deurs B (1992)
Internalization efficiency of the transferrin receptor
Exp Cell Res, 199 (1), 19-28
PubMed 1735458

O'Brien AD, Tesh VL, Donohue-Rolfe A, Jackson MP, Olsnes S, Sandvig K, Lindberg AA, Keusch GT (1992)
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
Curr Top Microbiol Immunol, 180, 65-94
PubMed 1324134

Prydz K, Hansen SH, Sandvig K, van Deurs B (1992)
Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells
J Cell Biol, 119 (2), 259-72
PubMed 1400572

Sandvig K, Dubinina E, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
Protein toxins: mode of action and cell entry
Biochem Soc Trans, 20 (4), 724-7
PubMed 1487049

Sandvig K, Garred O, Prydz K, Kozlov JV, Hansen SH, van Deurs B (1992)
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
Nature, 358 (6386), 510-2
PubMed 1641040

Sandvig K, van Deurs B (1992)
Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide
Exp Cell Res, 200 (2), 253-62
PubMed 1572394

Publications 1991

Hansen SH, Sandvig K, van Deurs B (1991)
The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
J Cell Biol, 113 (4), 731-41
PubMed 1673969

Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
PubMed 2046087

Madshus IH, Stenmark H, Sandvig K, Olsnes S (1991)
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632

Melby EL, Prydz K, Olsnes S, Sandvig K (1991)
Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
J Cell Biochem, 47 (3), 251-60
PubMed 1791187

Olsnes S, Kozlov JV, van Deurs B, Sandvig K (1991)
Bacterial protein toxins acting on intracellular targets
Semin Cell Biol, 2 (1), 7-14
PubMed 1954345

Sandvig K, Prydz K, Hansen SH, van Deurs B (1991)
Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
J Cell Biol, 115 (4), 971-81
PubMed 1955466

Sandvig K, Prydz K, Ryd M, van Deurs B (1991)
Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells
J Cell Biol, 113 (3), 553-62
PubMed 1901867

Sandvig K, van Deurs B (1991)
Endocytosis without clathrin (a minireview)
Cell Biol Int Rep, 15 (1), 3-8
PubMed 1900741

Stenmark H, Moskaug JO, Madshus IH, Sandvig K, Olsnes S (1991)
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
PubMed 2040642

Wiedłocha A, Sandvig K, Walzel H, Radzikowsky C, Olsnes S (1991)
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131

Publications 1990

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1990)
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980

Olsnes S, Stenmark H, Moskaug JO, McGill S, Madshus IH, Sandvig K (1990)
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
PubMed 1696341

Sandvig K, van Deurs B (1990)
Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis
J Biol Chem, 265 (11), 6382-8
PubMed 1969411

Tønnessen TI, Sandvig K, Olsnes S (1990)
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
PubMed 2163200

van Deurs B, Hansen SH, Petersen OW, Melby EL, Sandvig K (1990)
Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium
Eur J Cell Biol, 51 (1), 96-109
PubMed 2328741

Publications 1989

Hansen SH, Petersen OW, Sandvig K, Olsnes S, van Deurs B (1989)
Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
Exp Cell Res, 185 (2), 373-86
PubMed 2689197

McGill S, Stenmark H, Sandvig K, Olsnes S (1989)
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
PubMed 2684631

Moskaug JO, Sandvig K, Olsnes S (1989)
Role of anions in low pH-induced translocation of diphtheria toxin
J Biol Chem, 264 (19), 11367-72
PubMed 2500440

Moskaug JO, Sletten K, Sandvig K, Olsnes S (1989)
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
J Biol Chem, 264 (26), 15709-13
PubMed 2768283

Olsnes S, Sandvig K, Petersen OW, van Deurs B (1989)
Immunotoxins--entry into cells and mechanisms of action
Immunol Today, 10 (9), 291-5
PubMed 2686677

Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882

OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751

Sandvig K, Olsnes S, Brown JE, Petersen OW, van Deurs B (1989)
Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
J Cell Biol, 108 (4), 1331-43
PubMed 2564398

Sandvig K, Olsnes S, Petersen OW, Van Deurs B (1989)
Control of coated-pit function by cytoplasmic pH
Methods Cell Biol, 32, 365-82
PubMed 2575206

Stenmark H, McGill S, Olsnes S, Sandvig K (1989)
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
PubMed 2479538

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
PubMed 2818647

van Deurs B, Petersen OW, Olsnes S, Sandvig K (1989)
The ways of endocytosis
Int Rev Cytol, 117, 131-77
PubMed 2573583

van Deurs B, Petersen OW, Sandvig K, Olsnes S (1989)
[Endocytosis, intracellular transport and sorting of proteins]
Nord Med, 104 (1), 9-11
PubMed 2911460

Publications 1988

Holtskog R, Sandvig K, Olsnes S (1988)
Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
Oncology, 45 (3), 172-9
PubMed 3368193

Moskaug JO, Sandvig K, Olsnes S (1988)
Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
J Biol Chem, 263 (5), 2518-25
PubMed 3339019

Olsnes S, Moskaug JO, Stenmark H, Sandvig K (1988)
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
PubMed 3072713

Olsnes S, Sandvig K (1988)
How protein toxins enter and kill cells
Cancer Treat Res, 37, 39-73
PubMed 2908634

Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517

Sandvig K, Olsnes S (1988)
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
J Biol Chem, 263 (25), 12352-9
PubMed 2457582

Sandvig K, Olsnes S, Petersen OW, van Deurs B (1988)
Inhibition of endocytosis from coated pits by acidification of the cytosol
J Cell Biochem, 36 (1), 73-81
PubMed 2893802

Stenmark H, Olsnes S, Sandvig K (1988)
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666

van Deurs B, Sandvig K, Petersen OW, Olsnes S, Simons K, Griffiths G (1988)
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
J Cell Biol, 106 (2), 253-67
PubMed 2892843

Publications 1987

Madshus IH, Sandvig K, Olsnes S, van Deurs B (1987)
Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
J Cell Physiol, 131 (1), 14-22
PubMed 3032992

Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
PubMed 3571337

Moskaug JO, Sandvig K, Olsnes S (1987)
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
J Biol Chem, 262 (21), 10339-45
PubMed 3112141

Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
PubMed 3624315

Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
PubMed 3606992

Sandvig K, Brown JE (1987)
Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells
Infect Immun, 55 (2), 298-303
PubMed 3542829

Sandvig K, Moskaug JO (1987)
Pseudomonas toxin binds triton X-114 at low pH
Biochem J, 245 (3), 899-901
PubMed 3117052

Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987)
Acidification of the cytosol inhibits endocytosis from coated pits
J Cell Biol, 105 (2), 679-89
PubMed 2887575

Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
PubMed 3624314

van Deurs B, Petersen OW, Olsnes S, Sandvig K (1987)
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
Exp Cell Res, 171 (1), 137-52
PubMed 3622628

Aarnes CM, Madshus IH, Guillemot JC, Sandvig K, Olsnes S (1987)
Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
Exp Cell Res, 170 (2), 483-90
PubMed 3036553

Publications 1986

Olsnes S, Carvajal E, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
J Biol Chem, 261 (4), 1562-9
PubMed 3632976

Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
J Biol Chem, 261 (4), 1553-61
PubMed 3944101

Olsnes S, Sandvig K (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
J Biol Chem, 261 (4), 1542-52
PubMed 3944100

Olsnes S, Tønnessen TI, Sandvig K (1986)
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
PubMed 3949885

Sandvig K, Olsnes S (1986)
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
J Biol Chem, 261 (4), 1570-5
PubMed 2418015

SANDVIG K, TONNESSEN TI, SAND O, OLSNES S (1986)
REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
J. Biol. Chem., 261 (25), 1639-1644

Sandvig K, Tønnessen TI, Olsnes S (1986)
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563

Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160

van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
PubMed 3001103

Publications 1985

Guillemot JC, Sundan A, Olsnes S, Sandvig K (1985)
Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
J Cell Physiol, 122 (2), 193-9
PubMed 3844014

Madshus IH, Sandvig K, Olsnes S (1985)
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
Exp Cell Res, 160 (1), 240-4
PubMed 2995095

Olsnes S, Carvajal E, Sundan A, Sandvig K (1985)
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
Biochim Biophys Acta, 846 (3), 334-41
PubMed 4041483

Olsnes S, Sandvig K, Madshus IH, Sundan A (1985)
Entry mechanisms of protein toxins and picornaviruses
Biochem Soc Symp, 50, 171-91
PubMed 3915869

OLSNES S, SANDVIG K, MADSHUS IH, SUNDAN A (1985)
ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
Biochem. Soc. Symp. (50), 171-191

Sandvig K, Olsnes S (1985)
Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
Biochem J, 228 (2), 521-3
PubMed 2990449

Sandvig K, Sundan A, Olsnes S (1985)
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
J Cell Physiol, 124 (1), 54-60
PubMed 3930519

Stirpe F, Barbieri L, Abbondanza A, Falasca AI, Brown AN, Sandvig K, Olsnes S, Pihl A (1985)
Properties of volkensin, a toxic lectin from Adenia volkensii
J Biol Chem, 260 (27), 14589-95
PubMed 3932357

STIRPE F, BARBIERI L, ABBONDANZA A, FALASCA AI, BROWN ANF, SANDVIG K, OLSNES S, PIHL A (1985)
PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
J. Biol. Chem., 260 (27), 4589-4595

van Deurs B, Pedersen LR, Sundan A, Olsnes S, Sandvig K (1985)
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
Exp Cell Res, 159 (2), 287-304
PubMed 2863159

Publications 1984

Madshus IH, Olsnes S, Sandvig K (1984)
Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
Virology, 139 (2), 346-57
PubMed 6097029

Madshus IH, Olsnes S, Sandvig K (1984)
Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
J Cell Biol, 98 (4), 1194-200
PubMed 6325467

Madshus IH, Olsnes S, Sandvig K (1984)
Requirements for entry of poliovirus RNA into cells at low pH
EMBO J, 3 (9), 1945-50
PubMed 6092049

Sandvig K, Madshus IH, Olsnes S (1984)
Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
Biochem J, 219 (3), 935-40
PubMed 6331401

Sandvig K, Olsnes S (1984)
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
J Cell Physiol, 119 (1), 7-14
PubMed 6707104

Sandvig K, Olsnes S (1984)
Receptor-mediated entry of protein toxins into cells
Acta Histochem Suppl, 29, 79-94
PubMed 6144140

Sandvig K, Sundan A, Olsnes S (1984)
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
J Cell Biol, 98 (3), 963-70
PubMed 6699094

Sundan A, Sandvig K, Olsnes S (1984)
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
Cancer Res, 44 (11), 4919-23
PubMed 6435858

Sundan A, Sandvig K, Olsnes S (1984)
Calmodulin antagonists sensitize cells to pseudomonas toxin
J Cell Physiol, 119 (1), 15-22
PubMed 6707099

Publications 1983

Sundan A, Sandvig K, Olsnes S (1983)
Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
Biochem Biophys Res Commun, 117 (2), 562-7
PubMed 6318763

Sundan A, Sandvig K, Olsnes S (1983)
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
Biochim Biophys Acta, 761 (3), 296-302
PubMed 6652111

SUNDAN A, SANDVIG K, OLSNES S (1983)
DANCYLCADAVERINE ELIMINATES CALMODULIN STIMULATION OF PHOSPHODIESTERASE
Biochem. Biophys. Res. Commun., 117 (2), 562-567

Publications 1982

Olsnes S, Haylett T, Sandvig K (1982)
The toxic lectin modeccin
Methods Enzymol, 83, 357-62
PubMed 6178935

Olsnes S, Stirpe F, Sandvig K, Pihl A (1982)
Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
J Biol Chem, 257 (22), 13263-70
PubMed 7142144

Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
J Biol Chem, 257 (13), 7495-503
PubMed 6806276

Sandvig K, Olsnes S (1982)
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
J Biol Chem, 257 (13), 7504-13
PubMed 7085634

Stirpe F, Sandvig K, Olsnes S, Pihl A (1982)
Action of viscumin, a toxic lectin from mistletoe, on cells in culture
J Biol Chem, 257 (22), 13271-7
PubMed 7142145

Sundan A, Olsnes S, Sandvig K, Pihl A (1982)
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
J Biol Chem, 257 (16), 9733-9
PubMed 7107588

Publications 1981

Sandvig K, Olsnes S (1981)
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
J Biol Chem, 256 (17), 9068-76
PubMed 7263699

Sandvig K, Olsnes S (1981)
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
Biochem J, 194 (3), 821-7
PubMed 7306026

Publications 1980

Sandvig K (1980)
[Intracellular mediators for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (15), 1021-23
PubMed 6250248

Sandvig K (1980)
Corneal Changes During Chloroquine Treatment: An investigation of 70 patients with chronic rheumatoid arthritis receiving chloroquine treatment
Scand J Rheumatol, 9 (1), 150-6
PubMed 19919350

Sandvig K (1980)
[Receptors for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (14), 964-6, 970
PubMed 6250247

Sandvig K, Olsnes S (1980)
Diphtheria toxin entry into cells is facilitated by low pH
J Cell Biol, 87 (3 Pt 1), 828-32
PubMed 7462324

Publications 1979

Sandvig K, Olsnes S (1979)
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
Exp Cell Res, 121 (1), 15-25
PubMed 446525

Sandvig K, Olsnes S, Pihl A (1979)
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
Biochem Biophys Res Commun, 90 (2), 648-55
PubMed 508328

Publications 1978

Olsnes S, Sandvig K, Eiklid K, Pihl A (1978)
Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
J Supramol Struct, 9 (1), 15-25
PubMed 732310

Sandvig K (1978)
Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures
FEBS Lett, 89 (2), 233-6
PubMed 658411

Sandvig K, Olsnes S, Pihl A (1978)
Chemical modifications of the toxic lectins abrin and ricin
Eur J Biochem, 84 (2), 323-31
PubMed 639792

Sandvig K, Olsnes S, Pihl A (1978)
Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
Eur J Biochem, 88 (1), 307-13
PubMed 78847

Sandvig K, Olsnes S, Pihl A (1978)
Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
Eur J Biochem, 82 (1), 13-23
PubMed 620666

Publications 1977

REFSNES K, HAYLETT T, SANDVIG K, OLSNES S (1977)
MODECCIN - PLANT TOXIN INHIBITING PROTEIN-SYNTHESIS
Biochem. Biophys. Res. Commun., 79 (4), 1176-1183

Refsnes K, Haylett T, Sandvig K, Olsnes S (1977)
Modeccin--a plant toxin inhibiting protein synthesis
Biochem Biophys Res Commun, 79 (4), 1176-83
PubMed 603653

Publications 1976

Olsnes S, Sandvig K, Refsnes K, Pihl A (1976)
Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
J Biol Chem, 251 (13), 3985-92
PubMed 932017

Sandvig K, Olsnes S, Pihl A (1976)
Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
J Biol Chem, 251 (13), 3977-84
PubMed 6468