Kanthi Galappathi
Position: Department engineer, M.Sc.
Phone: +47 22 78 12 21
Email:
Education: M.Sc.
Research interests/projects: Microenvironment- and radiation-induced metastasis
 

Author network for Kanthi Galappathi by COREMINE medical


Publications 2017

Andersen LMK, Wegner CS, Simonsen TG, Huang R, Gaustad JV, Hauge A, Galappathi K, Rofstad EK (2017)
Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts
Oncotarget (in press)
PubMed 28624797

Publications 2016

Rofstad EK, Huang R, Galappathi K, Andersen LM, Wegner CS, Hauge A, Gaustad JV, Simonsen TG (2016)
Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis
Oncotarget, 7 (35), 56986-56997
PubMed 27486768

Rofstad EK, Simonsen TG, Huang R, Andersen LM, Galappathi K, Ellingsen C, Wegner CS, Hauge A, Gaustad JV (2016)
Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix
Cancer Lett, 373 (2), 147-55
PubMed 26828134

Publications 2015

Ellingsen C, Andersen LM, Galappathi K, Rofstad EK (2015)
Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix
BMC Cancer, 15, 805
PubMed 26502718

Publications 2014

Hompland T, Ellingsen C, Galappathi K, Rofstad EK (2014)
DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts
BMC Cancer, 14, 92
PubMed 24528854

Rofstad EK, Galappathi K, Mathiesen BS (2014)
Tumor interstitial fluid pressure-a link between tumor hypoxia, microvascular density, and lymph node metastasis
Neoplasia, 16 (7), 586-94
PubMed 25117980

Publications 2013

Ellingsen C, Hompland T, Galappathi K, Mathiesen B, Rofstad EK (2013)
DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts
Radiother Oncol, 110 (2), 335-41
PubMed 24231244

Hompland T, Ellingsen C, Galappathi K, Rofstad EK (2013)
Connective tissue of cervical carcinoma xenografts: associations with tumor hypoxia and interstitial fluid pressure and its assessment by DCE-MRI and DW-MRI
Acta Oncol, 53 (1), 6-15
PubMed 23445339

Publications 2012

Ellingsen C, Ovrebø KM, Galappathi K, Mathiesen B, Rofstad EK (2012)
pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (4), 1317-23
PubMed 22270159

Ovrebø KM, Ellingsen C, Galappathi K, Rofstad EK (2012)
Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of melanoma xenografts
Int J Radiat Oncol Biol Phys, 83 (1), e121-7
PubMed 22381901

Publications 2011

Gulliksrud K, Galappathi K, Rofstad EK (2011)
Interstitial fluid pressure and vascularity of intradermal and intramuscular human tumor xenografts
Int J Radiat Oncol Biol Phys, 80 (1), 258-64
PubMed 21255944

Gulliksrud K, Hompland T, Galappathi K, Rofstad EK (2011)
Assessment of tumor hypoxia and interstitial fluid pressure by gadomelitol-based dynamic contrast-enhanced magnetic resonance imaging
Radiother Oncol, 101 (1), 217-22
PubMed 21840612

Publications 2010

Egeland TA, Gaustad JV, Galappathi K, Rofstad EK (2010)
Magnetic resonance imaging of tumor necrosis
Acta Oncol, 50 (3), 427-34
PubMed 20950229

Ellingsen C, Egeland TA, Galappathi K, Rofstad EK (2010)
Dynamic contrast-enhanced magnetic resonance imaging of human cervical carcinoma xenografts: pharmacokinetic analysis and correlation to tumor histomorphology
Radiother Oncol, 97 (2), 217-24
PubMed 20656365

Gulliksrud K, Mathiesen B, Galappathi K, Rofstad EK (2010)
Quantitative assessment of hypoxia in melanoma xenografts by dynamic contrast-enhanced magnetic resonance imaging: intradermal versus intramuscular tumors
Radiother Oncol, 97 (2), 233-8
PubMed 20934767

Rofstad EK, Gaustad JV, Egeland TA, Mathiesen B, Galappathi K (2010)
Tumors exposed to acute cyclic hypoxic stress show enhanced angiogenesis, perfusion and metastatic dissemination
Int J Cancer, 127 (7), 1535-46
PubMed 20091868

Rofstad EK, Ruud EB, Mathiesen B, Galappathi K (2010)
Associations between radiocurability and interstitial fluid pressure in human tumor xenografts without hypoxic tissue
Clin Cancer Res, 16 (3), 936-45
PubMed 20103667

Publications 2009

Rofstad EK, Gaustad JV, Brurberg KG, Mathiesen B, Galappathi K, Simonsen TG (2009)
Radiocurability is associated with interstitial fluid pressure in human tumor xenografts
Neoplasia, 11 (11), 1243-51
PubMed 19881960

Publications 2008

Gulliksrud K, Vestvik IK, Galappathi K, Mathiesen B, Rofstad EK (2008)
Detection of different hypoxic cell subpopulations in human melanoma xenografts by pimonidazole immunohistochemistry
Radiat Res, 170 (5), 638-50
PubMed 18959463

Publications 2007

Rofstad EK, Galappathi K, Mathiesen B, Ruud EB (2007)
Fluctuating and diffusion-limited hypoxia in hypoxia-induced metastasis
Clin Cancer Res, 13 (7), 1971-8
PubMed 17360973

Publications 2006

Rofstad EK, Mathiesen B, Kindem K, Galappathi K (2006)
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
Cancer Res, 66 (13), 6699-707
PubMed 16818644

Publications 2005

Rofstad EK, Mathiesen B, Henriksen K, Kindem K, Galappathi K (2005)
The tumor bed effect: increased metastatic dissemination from hypoxia-induced up-regulation of metastasis-promoting gene products
Cancer Res, 65 (6), 2387-96
PubMed 15781654

Publications 2004

Rofstad EK, Galappathi K, Mathiesen B (2004)
Thrombospondin-1 treatment prevents growth of dormant lung micrometastases after surgical resection and curative radiation therapy of the primary tumor in human melanoma xenografts
Int J Radiat Oncol Biol Phys, 58 (2), 493-9
PubMed 14751520

Rofstad EK, Mathiesen B, Galappathi K (2004)
Increased metastatic dissemination in human melanoma xenografts after subcurative radiation treatment: radiation-induced increase in fraction of hypoxic cells and hypoxia-induced up-regulation of urokinase-type plasminogen activator receptor
Cancer Res, 64 (1), 13-8
PubMed 14729600

Publications 2003

Rofstad EK, Henriksen K, Galappathi K, Mathiesen B (2003)
Antiangiogenic treatment with thrombospondin-1 enhances primary tumor radiation response and prevents growth of dormant pulmonary micrometastases after curative radiation therapy in human melanoma xenografts
Cancer Res, 63 (14), 4055-61
PubMed 12874006

Publications 2002

Rofstad EK, Rasmussen H, Galappathi K, Mathiesen B, Nilsen K, Graff BA (2002)
Hypoxia promotes lymph node metastasis in human melanoma xenografts by up-regulating the urokinase-type plasminogen activator receptor
Cancer Res, 62 (6), 1847-53
PubMed 11912164

Rofstad EK, Tunheim SH, Mathiesen B, Graff BA, Halsør EF, Nilsen K, Galappathi K (2002)
Pulmonary and lymph node metastasis is associated with primary tumor interstitial fluid pressure in human melanoma xenografts
Cancer Res, 62 (3), 661-4
PubMed 11830516