Ola Didrik Saugstad
Position: Professor, Head of Department, MD, PhD, FRCPE
Phone: +47 23 07 27 94
Email:

Curriculum vitae for Ola Didrik Saugstad

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Full name and adress
Ola Didrik Saugstad: Vindernvn 22, 0373 Oslo, Norway
Office adress: Department of Pediatric Research, Rikshospitalet, 0027 Oslo, Norway
+47-22 86 91 10/11, Fax: + 47-22 86 91 17
E- mail: o.d.saugstad@medisin.uio.no

Current position
Professor of Pediatrics at the University of Oslo.
Director of Department of Pediatric Research
Consultant in Neonatology
Rikshospitalet, University of Oslo, Norway.

Place of birth - Citizenship - marital status
Born in Norway, March 5th 1947, Norwegian citizen
Married with Anne-Margrete in 1973
Two children, Andreas born in 1974 and Maria born in 1978 .

Education and training

  • 1973: MD, University of Oslo
  • 1977: Dr med (Ph D), University of Oslo.
  • 1973-74: Research Fellow at the Perinatal Research Unit, Department of Pediatrics, University Hospital, Uppsala, Sweden
  • 1974-76: Research Fellow at Institute for Surgical Research, The National Hospital, Oslo, Norway (Fellow of the Norwegian Research Council).
  • 1980/81: Recipient of a Fogarty Postdoctoral Fellowship (NIH) at the University of California San Diego, Department of Neonatology/Perinatology.
  • 1986: 3 months Visiting Associate Research Pediatrician at University of California San Francisco, Cardiovascular Research Institute.
  • 1979-84: Training in Pediatrics and Neonatology at Ullevål Sykehus (Oslo City Hospital) and The National Hospital, Oslo.
  • 1984: Certified Pediatrician in Norway
  • 1986- to present: Consultant in Neonatology at The National Hospital.
  • 1991 (June 1st) - to present: Professor 1 in Pediatrics and Director of Department of Pediatric Research, The National Hospital, University of Oslo.

Research areas and publications

  • Published more than 300 articles and book chapters in journals and books. Of these 270 are recorded in Medline. The main topics are hypoxia and the purine metabolism, hypoxia-reoxygenation injury, the effect of oxygen radicals in the neonatal period, and mechanisms of lung injury.
  • Published 3 books in Norwegian
  • Edited three books.
  • Supervisor for 24 completed PhD/Dr med
  • Advisor for WHO in Newborn medicine

Invited lecturer

Invited more than 250 times as guest speaker to international meetings/institutions in Africa, Asia, Australia, Europe, and the USA.

Member of editorial boards of medical journals

Editor

  • Applied Cardiopulmonary Pathophysiology (Section Editor Neonatology) 1992-98
  • Prenatal and Neonatal Medicine (Specialty Editor on Resuscitation) 1996-1999
  • Prenatal and Neonatal Medicine (Editor) 1999-2001
  • Pediatric Research (Consulting Editor) 1999-
  • J Maternal Fetal Neonatal Medicine (Editor in Chief) 2001-2004
  • Biology of the Neonate (Section editor) 2002-203
  • Acta Paediatrica (Assoc Editor 2005 -2008

Guest editor

  • Seminars in Neonatology (volume 3, 1998)

Editorial Board member

  • J Perinatal Medicine
  • Biology of the Neonate
  • J Fetal and Maternal Investigation (1992-98).
  • Acta Paediatrica (1998-2005, 2008-)
  • J of Perinatology
  • Acta Pediatrica Espanola

Council membership in scientific societies

  • Council Member of European Society for Pediatric Research (ESPR) 1987-90
  • Secretary of Working Group on Neonatology in ESPR 1990-93
  • Founder of the Norwegian Society of Perinatal Medicine in 1987
  • Chairman of the Norwegian Society of Perinatal Medicine1987-89 and Council Member from 1989-1995
  • Member of the Executive Board of the European Assoc of Perinatal Medicine 1996-2000
  • Member of Scientific Committee of World Association of Perinatal Medicine 1998-
  • President Elect European Association of Perinatal Medicine 2000-2002
  • Member of Board of Trustees International Pediatric Foundation 2000 -2004
  • President European Associaton of Perinatal Medicine 2002-2004
  • Past President European Association of Perinatal Medicine 2004-2006

Member of international societies

  • European Society for Pediatric Research
  • Society for Pediatric Research (USA)
  • The Neonatal Society (UK).
  • European Society for Pediatric Intensive Care
  • Fellow to the Royal College of Physicians (Edinburgh)
  • International Academy of Perinatal Medicine

Scientific boards

International meetings

  • President of the "8th International Workshop on Surfactant Replacement", Oslo, 1993.
  • President of the XVIII European Congress of Perinatal Medicine, Oslo, 2002
  • President of the "XXI International Workshop on Surfactant Replacement", Oslo 2006
  • President 1st World Congress of Neonatology, Egypt 2008

National meetings

  • Chairman of 1st Norwegian Perinatal Congress, Oslo, September, 1987
  • Chairman of 6th Norwegian Perinatal Congress, Oslo, November, 1992

Awards

  • Recipient of The Laerdal Foundations Nordic Award for Acute Medicine 1995
  • Fellow to The Royal College of Physicians Edinburgh 1996
  • Recipient of the Arvo Ylppo's International Award in Neonatal Medicine 1997
  • Honorary Member of the Hungarian Pediatric Association 2000
  • Virginia Apgar Prize 2001
  • Medinnova's Idea award 2001
  • Honorary member of the Norwegian Perinatal Society 2001
  • Honorary Member of the Finnish Perinatal Society, 2005
  • Honorary Member of the European Association of Perinatal Medicine 2006
  • The Human Protection Award (Norwegian) 2007
  • The Maternité Prize (European Association of Perinatal Medicine) 2008
  • Recent advances in Newborn Medicine, Wurzburg 2008 in honour of OD Saugstad

Reviewer

  • Acted as referee for more than 30 international medical journals

Bibliographied

  • Who's Who in the World 1996 - 2006
  • Dictionary of International Biography 1997 -2000
  • Leading Intellectuals in the World 2001

December 2008

Ola Didrik Saugstad

 

Author network for Ola Didrik Saugstad by COREMINE medical


Publications 2017

Aune D, Schlesinger S, Henriksen T, Saugstad OD, Tonstad S (2017)
Physical activity and the risk of preterm birth: a systematic review and meta-analysis of epidemiological studies
BJOG (in press)
PubMed 28374930

Kuligowski J, Solberg R, Sánchez-Illana Á, Pankratov L, Parra-Llorca A, Quintás G, Saugstad OD, Vento M (2017)
Plasma metabolite score correlates with Hypoxia time in a newly born piglet model for asphyxia
Redox Biol, 12, 1-7 (in press)
PubMed 28209514

Oei JL, Saugstad OD, Lui K, Wright IM, Smyth JP, Craven P, Wang YA, McMullan R, Coates E, Ward M, Mishra P, De Waal K, Travadi J, See KC, Cheah IG, Lim CT, Choo YM, Kamar AA, Cheah FC, Masoud A, Tarnow-Mordi W (2017)
Targeted Oxygen in the Resuscitation of Preterm Infants, a Randomized Clinical Trial
Pediatrics, 139 (1)
PubMed 28034908

Sánchez-Illana Á, Solberg R, Lliso I, Pankratov L, Quintás G, Saugstad OD, Vento M, Kuligowski J (2017)
Assessment of phospholipid synthesis related biomarkers for perinatal asphyxia: a piglet study
Sci Rep, 7, 40315
PubMed 28071721

Saugstad OD (2017)
50 Years Ago in The Journal of Pediatrics: The Incidence of Neonatal Hypoglycemia-A Completed Survey
J Pediatr, 180, 73
PubMed 28010802

Saugstad OD (2017)
50 Years Ago in The Journal of Pediatrics: Feeding Studies in Low-Birth-Weight Infants
J Pediatr, 184, 124
PubMed 28434564

Saugstad OD (2017)
Fish Oil in Pregnancy and Asthma in Offspring
N Engl J Med, 376 (12), 1191
PubMed 28332384

Saugstad OD (2017)
The Incidence of Neonatal Hypoglycemia-A Completed Survey
J. Pediatr., 180, 73-+

Solberg R, Longini M, Proietti F, Perrone S, Felici C, Porta A, Saugstad OD, Buonocore G (2017)
DHA Reduces Oxidative Stress after Perinatal Asphyxia: A Study in Newborn Piglets
Neonatology, 112 (1), 1-8 (in press)
PubMed 28142140

Solevåg AL, Schmölzer GM, Nakstad B, Saugstad OD, Cheung PY (2017)
Association between Brain and Kidney Near-Infrared Spectroscopy and Early Postresuscitation Mortality in Asphyxiated Newborn Piglets
Neonatology, 112 (1), 80-86 (in press)
PubMed 28380491

Publications 2016

Asadi-Azarbaijani B, Santos RR, Jahnukainen K, Braber S, van Duursen MB, Toppari J, Saugstad OD, Nurmio M, Oskam IC (2016)
Developmental effects of imatinib mesylate on follicle assembly and early activation of primordial follicle pool in postnatal rat ovary
Reprod Biol, 17 (1), 25-33
PubMed 28040471

Aschner JL, Gien J, Ambalavanan N, Kinsella JP, Konduri GG, Lakshminrusimha S, Saugstad OD, Steinhorn RH (2016)
Challenges, priorities and novel therapies for hypoxemic respiratory failure and pulmonary hypertension in the neonate
J Perinatol, 36 Suppl 2, S32-6
PubMed 27225964

Aune D, Sen A, Henriksen T, Saugstad OD, Tonstad S (2016)
Physical activity and the risk of gestational diabetes mellitus: a systematic review and dose-response meta-analysis of epidemiological studies
Eur J Epidemiol, 31 (10), 967-997
PubMed 27485519

Benterud T, Ystgaard MB, Manueldas S, Pankratov L, Alfaro-Cervello C, Florholmen G, Ahmed MS, Sandvik L, Norgren S, Bjørås M, Baumbusch LO, Solberg R, Saugstad OD (2016)
N-Acetylcysteine Amide Exerts Possible Neuroprotective Effects in Newborn Pigs after Perinatal Asphyxia
Neonatology, 111 (1), 12-21
PubMed 27497671

Bryn V, Aass HC, Skjeldal OH, Isaksen J, Saugstad OD, Ormstad H (2016)
Cytokine Profile in Autism Spectrum Disorders in Children
J Mol Neurosci, 61 (1), 1-7
PubMed 27730473

Buonocore G, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP (2016)
Sharing Progress in Neonatal (SPIN) Lung and Brain
Neonatology, 109 (4), 322-4
PubMed 27251786

Cháfer-Pericás C, Torres-Cuevas I, Sanchez-Illana A, Escobar J, Kuligowski J, Solberg R, Garberg HT, Huun MU, Saugstad OD, Vento M (2016)
Development of a reliable analytical method to determine lipid peroxidation biomarkers in newborn plasma samples
Talanta, 153, 152-7
PubMed 27130102

Escobar J, Sánchez-Illana Á, Kuligowski J, Torres-Cuevas I, Solberg R, Garberg HT, Huun MU, Saugstad OD, Vento M, Cháfer-Pericás C (2016)
Development of a reliable method based on ultra-performance liquid chromatography coupled to tandem mass spectrometry to measure thiol-associated oxidative stress in whole blood samples
J Pharm Biomed Anal, 123, 104-12
PubMed 26895495

Garberg HT, Huun MU, Baumbusch LO, Åsegg-Atneosen M, Solberg R, Saugstad OD (2016)
Temporal Profile of Circulating microRNAs after Global Hypoxia-Ischemia in Newborn Piglets
Neonatology, 111 (2), 133-139
PubMed 27750254

Garberg HT, Huun MU, Escobar J, Martinez-Orgado J, Løberg EM, Solberg R, Didrik Saugstad O (2016)
Short-term effects of cannabidiol after global hypoxia-ischemia in newborn piglets
Pediatr Res, 80 (5), 710-718
PubMed 27441365

Grytten J, Monkerud L, Skau I, Eskild A, Sørensen RJ, Saugstad OD (2016)
Saving Newborn Babies - The Benefits of Interventions in Neonatal Care in Norway over More Than 40 Years
Health Econ, 26 (3), 352-370
PubMed 26842217

Kessler J, Yli BM, Stray-Pedersen B, Jacobsen AF, Saugstad OD, Henriksen T (2016)
Why did the authors perform a meta-analysis of studies with primary endpoints they consider clinically unimportant?
Acta Obstet Gynecol Scand, 95 (5), 606-7
PubMed 26878842

Lakshminrusimha S, Saugstad OD (2016)
The fetal circulation, pathophysiology of hypoxemic respiratory failure and pulmonary hypertension in neonates, and the role of oxygen therapy
J Perinatol, 36 Suppl 2, S3-S11
PubMed 27225963

Manja V, Saugstad OD, Lakshminrusimha S (2016)
Oxygen Saturation Targets in Preterm Infants and Outcomes at 18-24 Months: A Systematic Review
Pediatrics, 139 (1)
PubMed 27940510

Oei JL, Ghadge A, Coates E, Wright IM, Saugstad OD, Vento M, Buonocore G, Nagashima T, Suzuki K, Hosono S, Davis PG, Craven P, Askie L, Dawson J, Garg S, Keech A, Rabi Y, Smyth J, Sinha S, Stenson B, Lui K, Hunter CL, Tarnow Mordi W, HOLISTIC (Higher Or Lower oxygen and Infant Saturation Targeting: International Collaboration) Study Group (2016)
Clinicians in 25 countries prefer to use lower levels of oxygen to resuscitate preterm infants at birth
Acta Paediatr, 105 (9), 1061-6
PubMed 27228325

Oei JL, Vento M, Rabi Y, Wright I, Finer N, Rich W, Kapadia V, Aune D, Rook D, Tarnow-Mordi W, Saugstad OD (2016)
Higher or lower oxygen for delivery room resuscitation of preterm infants below 28 completed weeks gestation: a meta-analysis
Arch Dis Child Fetal Neonatal Ed, 102 (1), F24-F30
PubMed 27150977

Rognlien AG, Wollen EJ, Atneosen-Åsegg M, Saugstad OD (2016)
Temporal Patterns of Gene Expression Profiles in the Neonatal Mouse Lung after Hypoxia-Reoxygenation
Neonatology, 111 (1), 45-54
PubMed 27529351

Rognum TO, Holmen S, Musse MA, Dahlberg PS, Stray-Pedersen A, Saugstad OD, Opdal SH (2016)
Estimation of time since death by vitreous humor hypoxanthine, potassium, and ambient temperature
Forensic Sci Int, 262, 160-5
PubMed 26994446

Saugstad OD (2016)
50 Years Ago in TheJournal ofPediatrics: Alkali Therapy in the Delivery Room
J Pediatr, 174, 62
PubMed 27346505

Saugstad OD (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (3), 205
PubMed 26860375

Saugstad OD (2016)
50 Years Ago in TheJournal ofPediatrics: Arterial Oxygen Tension in Premature Infants
J Pediatr, 176, 61
PubMed 27568249

Saugstad OD (2016)
50 Years Ago in The Journal of Pediatrics: Arterial Blood Gas Tensions and Acid-Base Balance in the Management of Respiratory Distress Syndrome
J Pediatr, 168, 98
PubMed 26719179

Saugstad OD (2016)
50 Years Ago in TheJournal ofPediatrics: Acetylcholine in the Treatment of Idiopathic Respiratory Distress Syndrome
J Pediatr, 178, 92
PubMed 27788846

Saugstad OD (2016)
The Newborn at the edge of viability
Acta Paediatr, 105 (11), 1249-1251
PubMed 27726194

Saugstad OD, Robertson NJ, Vento M (2016)
A critical review of the 2015 International Liaison Committee on Resuscitation treatment recommendations for resuscitating the newly born infant
Acta Paediatr, 105 (5), 442-4
PubMed 27062471

Saugstad OD, Soll RF (2016)
Assessing Heart Rate at Birth: Auscultation Is Still the Gold Standard
Neonatology, 110 (3), 238-40
PubMed 27250860

Saugstad OD, Stokkereit I (2016)
Children's Right to Health: Implications for Decision-Making in Newborn Medical Care
Pediatrics, 138 (1)
PubMed 27260696

Solberg R, Kuligowski J, Pankratov L, Escobar J, Quintás G, Lliso I, Sánchez-Illana Á, Saugstad OD, Vento M (2016)
Changes of the plasma metabolome of newly born piglets subjected to postnatal hypoxia and resuscitation with air
Pediatr Res, 80 (2), 284-92
PubMed 27055187

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Vento M, Visser GH, Halliday HL (2016)
European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2016 Update
Neonatology, 111 (2), 107-125
PubMed 27649091

Torres-Cuevas I, Kuligowski J, Cárcel M, Cháfer-Pericás C, Asensi M, Solberg R, Cubells E, Nuñez A, Saugstad OD, Vento M, Escobar J (2016)
Protein-bound tyrosine oxidation, nitration and chlorination by-products assessed by ultraperformance liquid chromatography coupled to tandem mass spectrometry
Anal Chim Acta, 913, 104-10
PubMed 26944994

Vento M, Schmölzer G, Cheung PY, Finer N, Solevåg AL, Oei JL, Saugstad OD (2016)
What initial oxygen is best for preterm infants in the delivery room?-A response to the 2015 neonatal resuscitation guidelines
Resuscitation, 101, e7-8
PubMed 26827713

Publications 2015

Benterud T, Pankratov L, Solberg R, Bolstad N, Skinningsrud A, Baumbusch L, Sandvik L, Saugstad OD (2015)
Perinatal Asphyxia May Influence the Level of Beta-Amyloid (1-42) in Cerebrospinal Fluid: An Experimental Study on Newborn Pigs
PLoS One, 10 (10), e0140966
PubMed 26501201

Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP (2015)
30 years of surfactant research - from basic science to new clinical treatments for the preterm infant
Neonatology, 107 (4), 314-6
PubMed 26044097

Egeland T, Angelsen A, Haug R, Henriksen JO, Lea TE, Saugstad OD (2015)
[T. Egeland and colleagues reply]
Tidsskr Nor Laegeforen, 135 (22), 2020-1
PubMed 26627271

Egeland T, Angelsen A, Haug R, Henriksen JO, Lea TE, Saugstad OD (2015)
[T. Egeland and colleagues reply]
Tidsskr Nor Laegeforen, 135 (22), 2021-2
PubMed 26627273

Egeland T, Angelsen A, Haug R, Henriksen JO, Lea TE, Saugstad OD (2015)
What exactly is myalgic encephalomyelitis?
Tidsskr Nor Laegeforen, 135 (19), 1756-9
PubMed 26486672

Lindenskov PH, Castellheim A, Saugstad OD, Mollnes TE (2015)
Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies
Neonatology, 107 (3), 225-30
PubMed 25721501

Samiee-Zafarghandy S, Saugstad OD, Fusch C (2015)
Do we have an answer when it comes to providing extremely preterm infants with optimal target oxygen saturation?
Acta Paediatr, 104 (3), e130-3
PubMed 25348933

Saugstad OD (2015)
Hyperoxia and cerebral vasoconstriction in healthy newborns
Acta Paediatr, 104 (7), 645-6
PubMed 26086478

Saugstad OD (2015)
Delivery room management of term and preterm newly born infants
Neonatology, 107 (4), 365-71
PubMed 26044106

Tataranno ML, Oei JL, Perrone S, Wright IM, Smyth JP, Lui K, Tarnow-Mordi WO, Longini M, Proietti F, Negro S, Saugstad OD, Buonocore G (2015)
Resuscitating preterm infants with 100% oxygen is associated with higher oxidative stress than room air
Acta Paediatr, 104 (8), 759-65
PubMed 25966608

Ystgaard MB, Sejersted Y, Løberg EM, Lien E, Yndestad A, Saugstad OD (2015)
Early Upregulation of NLRP3 in the Brain of Neonatal Mice Exposed to Hypoxia-Ischemia: No Early Neuroprotective Effects of NLRP3 Deficiency
Neonatology, 108 (3), 211-9
PubMed 26279061

Publications 2014

Arduini A, Escobar J, Vento M, Escrig R, Quintás G, Sastre J, Saugstad OD, Solberg R (2014)
Metabolic adaptation and neuroprotection differ in the retina and choroid in a piglet model of acute postnatal hypoxia
Pediatr Res, 76 (2), 127-34
PubMed 24819373

Aune D, Saugstad OD, Henriksen T, Tonstad S (2014)
Maternal body mass index and the risk of fetal death, stillbirth, and infant death: a systematic review and meta-analysis
JAMA, 311 (15), 1536-46
PubMed 24737366

Aune D, Saugstad OD, Henriksen T, Tonstad S (2014)
Physical activity and the risk of preeclampsia: a systematic review and meta-analysis
Epidemiology, 25 (3), 331-43
PubMed 24713878

Brabrand K, de Lange C, Emblem KE, Reinholt FP, Saugstad OD, Stokke ES, Munkeby BH (2014)
Contrast-enhanced ultrasound identifies reduced overall and regional renal perfusion during global hypoxia in piglets
Invest Radiol, 49 (8), 540-6
PubMed 24637585

Haaland E, Meland E, Magelssen M, Salbu H, Felde G, Saugstad OD, Rognum T (2014)
[No real loss of referral obligations]
Tidsskr Nor Laegeforen, 134 (17), 1646
PubMed 25223670

Janvier A, Barrington KJ, Aziz K, Bancalari E, Batton D, Bellieni C, Bensouda B, Blanco C, Cheung PY, Cohn F, Daboval T, Davis P, Dempsey E, Dupont-Thibodeau A, Ferretti E, Farlow B, Fontana M, Fortin-Pellerin E, Goldberg A, Hansen TW, Haward M, Kovacs L, Lapointe A, Lantos J, Morley C et al. (2014)
CPS position statement for prenatal counselling before a premature birth: Simple rules for complicated decisions
Paediatr Child Health, 19 (1), 22-4
PubMed 24627651

Kuligowski J, Pérez-Guaita D, Lliso I, Escobar J, León Z, Gombau L, Solberg R, Saugstad OD, Vento M, Quintás G (2014)
Detection of batch effects in liquid chromatography-mass spectrometry metabolomic data using guided principal component analysis
Talanta, 130, 442-8
PubMed 25159433

Mitra S, Aune D, Speer CP, Saugstad OD (2014)
Chorioamnionitis as a risk factor for retinopathy of prematurity: a systematic review and meta-analysis
Neonatology, 105 (3), 189-99
PubMed 24481268

Ramji S, Saugstad OD, Jain A (2014)
Current concepts of oxygen therapy in neonates
Indian J Pediatr, 82 (1), 46-52
PubMed 25326155

Rognlien AG, Wollen EJ, Atneosen-Åsegg M, Saugstad OD (2014)
Increased expression of inflammatory genes in the neonatal mouse brain after hyperoxic reoxygenation
Pediatr Res, 77 (2), 326-33
PubMed 25423075

Saugstad OD (2014)
Twins should be delivered before 38 weeks of gestation: AGAINST
BJOG, 121 (10), 1293
PubMed 25155320

Saugstad OD (2014)
New growth charts for newborn babies
Lancet, 384 (9946), 833-5
PubMed 25209472

Saugstad OD, Aune D, Aguar M, Kapadia V, Finer N, Vento M (2014)
Systematic review and meta-analysis of optimal initial fraction of oxygen levels in the delivery room at ≤32 weeks
Acta Paediatr, 103 (7), 744-51
PubMed 24716824

Sweet D, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Halliday HL, European Association of Perinatal Medicine (2014)
[European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants--2013 update]
Zhonghua Er Ke Za Zhi, 52 (10), 749-55
PubMed 25537540

Vento M, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP (2014)
More about surfactant, oxygen, caffeine and chronic lung disease
Neonatology, 105 (4), 320-2
PubMed 24931323

Wollen EJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Sejersted Y, Wright MS, Günther CC, Nygård S, Saugstad OD, Pietrzyk JJ (2014)
Hypoxia-reoxygenation affects whole-genome expression in the newborn eye
Invest Ophthalmol Vis Sci, 55 (3), 1393-401
PubMed 24458145

Publications 2013

Døhlen G, Antal EA, Castellheim A, Thaulow E, Kielland A, Saugstad OD (2013)
Hyperoxic resuscitation after hypoxia-ischemia induces cerebral inflammation that is attenuated by tempol in a reporter mouse model with very young mice
J Perinat Med, 41 (3), 251-7
PubMed 23241583

Hallman M, Curstedt T, Halliday HL, Saugstad OD, Speer CP (2013)
Better neonatal outcomes: oxygen, surfactant and drug delivery. Preface
Neonatology, 103 (4), 316-9
PubMed 23736008

Hameed NN, Abdul Jaleel RK, Saugstad OD (2013)
The use of continuous positive airway pressure in preterm babies with respiratory distress syndrome: a report from Baghdad, Iraq
J Matern Fetal Neonatal Med, 27 (6), 629-32
PubMed 23885695

Hansen TWR, Saugstad OD (2013)
Management of periviable newbornas in the Nordic countries.
Current Pediatric Reviews, 9, 19-24
PublikaID 194

Kro GA, Yli BM, Rasmussen S, Norèn H, Amer-Wåhlin I, Rosén KG, Stray-Pedersen B, Saugstad OD (2013)
Association between umbilical cord artery pCO₂ and the Apgar score; elevated levels of pCO₂ may be beneficial for neonatal vitality after moderate acidemia
Acta Obstet Gynecol Scand, 92 (6), 662-70
PubMed 23551012

Pietrzyk JJ, Kwinta P, Wollen EJ, Bik-Multanowski M, Madetko-Talowska A, Günther CC, Jagła M, Tomasik T, Saugstad OD (2013)
Gene expression profiling in preterm infants: new aspects of bronchopulmonary dysplasia development
PLoS One, 8 (10), e78585
PubMed 24194948

Salvesen B, Curstedt T, Mollnes TE, Saugstad OD (2013)
Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome
Neonatology, 105 (2), 128-35
PubMed 24356240

Saugstad OD (2013)
The oxygen paradox in the newborn: keep oxygen at normal levels
J Pediatr, 163 (4), 934-5
PubMed 23866716

Saugstad OD (2013)
Too Expensive to Treat? Finitude, Tragedy, and the Neonatal ICU
J. Bioethical Inq., 10 (2), 253-255

Saugstad OD (2013)
[Oxygen to premature births--a new scandal?]
Tidsskr Nor Laegeforen, 133 (19), 2062-4
PubMed 24129538

Saugstad OD (2013)
The Oxygen Paradox in the Newborn: Keep Oxygen at Normal Levels
J. Pediatr., 163 (4), 934-935

Saugstad OD, Aune D (2013)
Optimal oxygenation of extremely low birth weight infants: a meta-analysis and systematic review of the oxygen saturation target studies
Neonatology, 105 (1), 55-63
PubMed 24247112

Saugstad OD, Kwinta P, Wollen EJ, Bik-Multanowski M, Madetko-Talowska A, Jagła M, Tomasik T, Pietrzyk JJ (2013)
Impact of antenatal glucocorticosteroids on whole-genome expression in preterm babies
Acta Paediatr, 102 (4), 349-55
PubMed 23347050

Solberg R, Escobar J, Arduini A, Torres-Cuevas I, Lahoz A, Sastre J, Saugstad OD, Vento M, Kuligowski J, Quintás G (2013)
Metabolomic Analysis of the Effect of Postnatal Hypoxia on the Retina in a Newly Born Piglet Model
PLoS One, 8 (6), e66540
PubMed 23823578

Solevåg AL, Dannevig I, Šaltytė-Benth J, Saugstad OD, Nakstad B (2013)
Reliability of pulse oximetry in hypoxic newborn pigs
J Matern Fetal Neonatal Med, 27 (8), 833-8
PubMed 24090354

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Vento M, Halliday HL, European Association of Perinatal Medicine (2013)
European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants--2013 update
Neonatology, 103 (4), 353-68
PubMed 23736015

Wollen EJ, Sejersted Y, Wright MS, Bik-Multanowski M, Madetko-Talowska A, Günther CC, Nygård S, Kwinta P, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse lung after hypoxia and reoxygenation: hyperoxic reoxygenation affects mTOR signaling pathway, DNA repair, and JNK-pathway regulation
Pediatr Res, 74 (5), 536-44
PubMed 23999071

Wollen EJ, Sejersted Y, Wright MS, Madetko-Talowska A, Bik-Multanowski M, Kwinta P, Günther CC, Nygård S, Løberg EM, Ystgaard MB, Pietrzyk JJ, Saugstad OD (2013)
Transcriptome profiling of the newborn mouse brain after hypoxia-reoxygenation: hyperoxic reoxygenation induces inflammatory and energy failure responsive genes
Pediatr Res, 75 (4), 517-26
PubMed 24375083

World Health Organization Odon Device Research Group, Schvartzman JA, Krupitzki H, Betran AP, Requejo J, Bergel E, Fiorillo AE, Gadow EC, Vizcaino FM, von Petery F, Althabe F, Belizan J, Borruto F, Boulvain M, Di Renzo GC, Gülmezoglu M, Hofmeyr J, Judge K, Leung TY, Nguyen MH, Saugstad OD, Temmerman M, Treisser A, Vayena E, Merialdi M (2013)
Feasibility and safety study of a new device (Odón device) for assisted vaginal deliveries: study protocol
Reprod Health, 10, 33
PubMed 23822879

Wright CJ, Saugstad OD (2013)
OHRP and SUPPORT: lessons in balancing safety and improving the way we care for patients
J Pediatr, 163 (5), 1495-7
PubMed 24050739

Publications 2012

Alsharnoubi JM, Odland HH, Saugstad OD (2012)
Nicotine does not influence NF-κB activity in neonatal mice reoxygenated with room-air or 100% oxygen
J Matern Fetal Neonatal Med, 25 (10), 2102-5
PubMed 22489644

Barlinn J, Feet BA, Saugstad OD (2012)
[When the nervous system is affected and the heart stops]
Tidsskr Nor Laegeforen, 132 (4), 432
PubMed 22353839

Dalen ML, Liu X, Elstad M, Løberg EM, Saugstad OD, Rootwelt T, Thoresen M (2012)
Resuscitation with 100% oxygen increases injury and counteracts the neuroprotective effect of therapeutic hypothermia in the neonatal rat
Pediatr Res, 71 (3), 247-52
PubMed 22337259

Dannevig I, Solevåg AL, Saugstad OD, Nakstad B (2012)
Lung Injury in Asphyxiated Newborn Pigs Resuscitated from Cardiac Arrest - The Impact of Supplementary Oxygen, Longer Ventilation Intervals and Chest Compressions at Different Compression-to-Ventilation Ratios
Open Respir Med J, 6, 89-96
PubMed 23115599

Dannevig I, Solevåg AL, Sonerud T, Saugstad OD, Nakstad B (2012)
Brain inflammation induced by severe asphyxia in newborn pigs and the impact of alternative resuscitation strategies on the newborn central nervous system
Pediatr Res, 73 (2), 163-70
PubMed 23168577

de Lange C, Malinen E, Qu H, Johnsrud K, Skretting A, Saugstad OD, Munkeby BH (2012)
Dynamic FDG PET for assessing early effects of cerebral hypoxia and resuscitation in new-born pigs
Eur J Nucl Med Mol Imaging, 39 (5), 792-9
PubMed 22297457

Koh J, Yeo CL, Wright I, Lui K, Saugstad O, Tarnow-Mordi W, Smyth J, Oei JL (2012)
The use of oxygen for delivery room resuscitation of newborn infants in non-Western countries
Early Hum Dev, 88 (8), 631-5
PubMed 22321600

Odland HH, Brun H, Sejersted Y, Dalen M, Edvardsen T, Saugstad OD, Thaulow E (2012)
Myocardial longitudinal peak systolic acceleration (pSac): relationship to ejection phase, pressure, and contractility
Echocardiography, 29 (5), 541-53
PubMed 22329750

Osterholt HC, Lundeland B, Sonerud T, Saugstad OD, Nakstad B (2012)
The impact of hyaluronan on monocyte Toll-like receptor expression in term infant cord blood
Acta Paediatr, 101 (7), 706-13
PubMed 22372604

Pietrzyk JJ, Kwinta P, Bik-Multanowski M, Madetko-Talowska A, Jagła M, Tomasik T, Mitkowska Z, Wollen EJ, Nygård S, Saugstad OD (2012)
New insight into the pathogenesis of retinopathy of prematurity: assessment of whole-genome expression
Pediatr Res, 73 (4 Pt 1), 476-83
PubMed 23269122

Saugstad OD (2012)
[Apples and pears should not be compared]
Tidsskr Nor Laegeforen, 132 (4), 388-9
PubMed 22353820

Saugstad OD (2012)
Hyperoxia in the term newborn: more evidence is still needed for optimal oxygen therapy
Acta Paediatr, 101 (464), 34-8
PubMed 22404890

Saugstad OD, Sejersted Y, Solberg R, Wollen EJ, Bjørås M (2012)
Oxygenation of the newborn: a molecular approach
Neonatology, 101 (4), 315-25
PubMed 22940621

Saugstad OD, Vento M, Ramji S, Howard D, Soll RF (2012)
Neurodevelopmental outcome of infants resuscitated with air or 100% oxygen: a systematic review and meta-analysis
Neonatology, 102 (2), 98-103
PubMed 22677698

Solberg R, Longini M, Proietti F, Vezzosi P, Saugstad OD, Buonocore G (2012)
Resuscitation with supplementary oxygen induces oxidative injury in the cerebral cortex
Free Radic Biol Med, 53 (5), 1061-7
PubMed 22842050

Solberg R, Perrone S, Saugstad OD, Buonocore G (2012)
Risks and benefits of oxygen in the delivery room
J Matern Fetal Neonatal Med, 25 Suppl 1, 41-4
PubMed 22356586

Østerholt HC, Dannevig I, Wyckoff MH, Liao J, Akgul Y, Ramgopal M, Mija DS, Cheong N, Longoria C, Mahendroo M, Nakstad B, Saugstad OD, Savani RC (2012)
Antioxidant protects against increases in low molecular weight hyaluronan and inflammation in asphyxiated newborn pigs resuscitated with 100% oxygen
PLoS One, 7 (6), e38839
PubMed 22701723

Publications 2011

Dawson JA, Vento M, Finer NN, Rich W, Saugstad OD, Morley CJ, Davis PG (2011)
Managing oxygen therapy during delivery room stabilization of preterm infants
J Pediatr, 160 (1), 158-61
PubMed 21907350

de Lange C, Brabrand K, Emblem KE, Bjornerud A, Løberg EM, Saugstad OD, Munkeby BH (2011)
Cerebral perfusion in perinatal hypoxia and resuscitation assessed by transcranial contrast-enhanced ultrasound and 3 T MRI in newborn pigs
Invest Radiol, 46 (11), 686-96
PubMed 21730873

Lawn JE, Bahl R, Bergstrom S, Bhutta ZA, Darmstadt GL, Ellis M, English M, Kurinczuk JJ, Lee AC, Merialdi M, Mohamed M, Osrin D, Pattinson R, Paul V, Ramji S, Saugstad OD, Sibley L, Singhal N, Wall SN, Woods D, Wyatt J, Chan KY, Rudan I (2011)
Setting research priorities to reduce almost one million deaths from birth asphyxia by 2015
PLoS Med, 8 (1), e1000389
PubMed 21305038

Odland HH, Brun H, Sejersted Y, Dalen M, Edvardsen T, Saugstad OD, Thaulow E (2011)
Longitudinal myocardial contribution to peak systolic flow and stroke volume in the neonatal heart
Pediatr Res, 70 (4), 345-51
PubMed 21691252

Odland HH, Kro GA, Edvardsen T, Thaulow E, Saugstad OD (2011)
Impaired diastolic function and disruption of the force-frequency relationship in the right ventricle of newborn pigs resuscitated with 100% oxygen
Neonatology, 101 (2), 147-53
PubMed 21952615

Saugstad OD (2011)
A time to be born and a time to die: ethical challenges in the neonatal intensive care unit
Neonatology, 100 (2), 215-6
PubMed 21654182

Saugstad OD (2011)
[Oxygen to newborns]
Tidsskr Nor Laegeforen, 131 (24), 2488-90
PubMed 22170138

Saugstad OD (2011)
[Frequent, feared and manifold]
Tidsskr Nor Laegeforen, 131 (5), 477
PubMed 21383804

Saugstad OD (2011)
Is 21% oxygen best for newborn resuscitation? Reply
Lancet, 377 (9772), 1153

Saugstad OD, International Liason Committee on Resuscitation (2011)
New guidelines for newborn resuscitation--a critical evaluation
Acta Paediatr, 100 (8), 1058-62
PubMed 21457302

Saugstad OD, Speer CP, Halliday HL (2011)
Oxygen saturation in immature babies: revisited with updated recommendations
Neonatology, 100 (3), 217-8
PubMed 21757963

Sejersted Y, Hildrestrand GA, Kunke D, Rolseth V, Krokeide SZ, Neurauter CG, Suganthan R, Atneosen-Åsegg M, Fleming AM, Saugstad OD, Burrows CJ, Luna L, Bjørås M (2011)
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Proc Natl Acad Sci U S A, 108 (46), 18802-7
PubMed 22065741

Solevåg AL, Dannevig I, Wyckoff M, Saugstad OD, Nakstad B (2011)
Return of spontaneous circulation with a compression:ventilation ratio of 15:2 versus 3:1 in newborn pigs with cardiac arrest due to asphyxia
Arch Dis Child Fetal Neonatal Ed, 96 (6), F417-21
PubMed 21393311

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Halliday HL (2011)
[European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants-2010 update]
Zhonghua Er Ke Za Zhi, 49 (1), 27-33
PubMed 21429308

Vento M, Saugstad OD (2011)
Oxygen supplementation in the delivery room: updated information
J Pediatr, 158 (2 Suppl), e5-7
PubMed 21238706

Yli BM, Kro GA, Rasmussen S, Khoury J, Norèn H, Amer-Wåhlin I, Saugstad OD, Stray-Pedersen B (2011)
How does the duration of active pushing in labor affect neonatal outcomes?
J Perinat Med, 40 (2), 171-8
PubMed 22098306

Publications 2010

Baibarina E, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP (2010)
Global neonatal mortality and hypothermia for perinatal asphyxia. Preface
Neonatology, 97 (4), 356-7
PubMed 20551702

Dalen ML, Alme TN, Bjørås M, Munkeby BH, Rootwelt T, Saugstad OD (2010)
Reduced expression of DNA glycosylases in post-hypoxic newborn pigs undergoing therapeutic hypothermia
Brain Res, 1363, 198-205
PubMed 20883672

Dalen ML, Alme TN, Munkeby BH, Løberg EM, Pripp AH, Mollnes TE, Rootwelt T, Saugstad OD (2010)
Early protective effect of hypothermia in newborn pigs after hyperoxic, but not after normoxic, reoxygenation
J Perinat Med, 38 (5), 545-56
PubMed 20629493

Dannevig I, Solevåg AL, Wyckoff M, Saugstad OD, Nakstad B (2010)
Delayed onset of cardiac compressions in cardiopulmonary resuscitation of newborn pigs with asphyctic cardiac arrest
Neonatology, 99 (2), 153-62
PubMed 20829634

Finer N, Saugstad O, Vento M, Barrington K, Davis P, Duara S, Leone T, Lui K, Martin R, Morley C, Rabi Y, Rich W (2010)
Use of oxygen for resuscitation of the extremely low birth weight infant
Pediatrics, 125 (2), 389-91
PubMed 20100772

Keller M, Felderhoff-Mueser U, Lagercrantz H, Dammann O, Marlow N, Hüppi P, Buonocore G, Poets C, Simbruner G, Guimaraes H, Mader S, Merialdi M, Saugstad OD (2010)
Policy benchmarking report on neonatal health and social policies in 13 European countries
Acta Paediatr, 99 (11), 1624-9
PubMed 20500729

Kro GA, Yli BM, Rasmussen S, Norèn H, Amer-Wåhlin I, Saugstad OD, Stray-Pedersen B, Rosén KG (2010)
A new tool for the validation of umbilical cord acid-base data
BJOG, 117 (12), 1544-52
PubMed 20840525

Mandruzzato G, Alfirevic Z, Chervenak F, Gruenebaum A, Heimstad R, Heinonen S, Levene M, Salvesen K, Saugstad O, Skupski D, Thilaganathan B, World Association of Perinatal Medicine (2010)
Guidelines for the management of postterm pregnancy
J Perinat Med, 38 (2), 111-9
PubMed 20156009

Odland HH, Kro GA, Munkeby BH, Edvardsen T, Saugstad OD, Thaulow E (2010)
Ejection time-corrected systolic velocity improves accuracy in the evaluation of myocardial dysfunction: a study in piglets
Pediatr Cardiol, 31 (7), 1070-8
PubMed 20721662

Salvesen B, Stenvik J, Rossetti C, Saugstad OD, Espevik T, Mollnes TE (2010)
Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner
Mol Immunol, 47 (6), 1226-34
PubMed 20092898

Saugstad OD (2010)
Oxygen and oxidative stress in bronchopulmonary dysplasia
J Perinat Med, 38 (6), 571-7
PubMed 20807008

Saugstad OD (2010)
Why are we still using oxygen to resuscitate term infants?
J Perinatol, 30 Suppl, S46-50
PubMed 20877407

Saugstad OD (2010)
[Better prognosis for the extremely premature infants]
Tidsskr Nor Laegeforen, 130 (1), 52-4
PubMed 20094127

Saugstad OD (2010)
[The responsibility of university hospitals]
Tidsskr Nor Laegeforen, 130 (7), 721
PubMed 20379327

Saugstad OD (2010)
Resuscitation of newborn infants: from oxygen to room air
Lancet, 376 (9757), 1970-1
PubMed 20663546

Saugstad OD (2010)
Reducing global neonatal mortality is possible
Neonatology, 99 (4), 250-7
PubMed 21088433

Saugstad OD, Aune D (2010)
In search of the optimal oxygen saturation for extremely low birth weight infants: a systematic review and meta-analysis
Neonatology, 100 (1), 1-8
PubMed 21150224

Skupski DW, Chervenak FA, McCullough LB, Bancalari E, Haumont D, Simeoni U, Saugstad O, Donn S, Arabin B, Greenough A, Donzelli G, Levene M, Sen C, Carbonell X, Dudenhausen JW, Vladareanu R, Antsaklis A, Papp Z, Aksit M, Carrapato M (2010)
Ethical dimensions of periviability
J Perinat Med, 38 (6), 579-83
PubMed 20807009

Solberg R, Andresen JH, Pettersen S, Wright MS, Munkeby BH, Charrat E, Khrestchatisky M, Rivera S, Saugstad OD (2010)
Resuscitation of hypoxic newborn piglets with supplementary oxygen induces dose-dependent increase in matrix metalloproteinase-activity and down-regulates vital genes
Pediatr Res, 67 (3), 250-6
PubMed 20010314

Solberg R, Enot D, Deigner HP, Koal T, Scholl-Bürgi S, Saugstad OD, Keller M (2010)
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs
PLoS One, 5 (3), e9606
PubMed 20231903

Solberg R, Løberg EM, Andresen JH, Wright MS, Charrat E, Khrestchatisky M, Rivera S, Saugstad OD (2010)
Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNF
PLoS One, 5 (12), e14261
PubMed 21151608

Solevåg AL, Dannevig I, Nakstad B, Saugstad OD (2010)
Resuscitation of severely asphyctic newborn pigs with cardiac arrest by using 21% or 100% oxygen
Neonatology, 98 (1), 64-72
PubMed 20068361

Solevåg AL, Dannevig I, Wyckoff M, Saugstad OD, Nakstad B (2010)
Extended series of cardiac compressions during CPR in a swine model of perinatal asphyxia
Resuscitation, 81 (11), 1571-6
PubMed 20638769

Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, Simeoni U, Speer CP, Halliday HL, European Association of Perinatal Medicine (2010)
European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2010 update
Neonatology, 97 (4), 402-17
PubMed 20551710

Vento M, Saugstad OD (2010)
Resuscitation of the term and preterm infant
Semin Fetal Neonatal Med, 15 (4), 216-22
PubMed 20451481

Vento M, Saugstad OD (2010)
Oxygen as a therapeutic agent in neonatology: a comprehensive approach
Semin Fetal Neonatal Med, 15 (4), 185
PubMed 20494637

Publications 2009

Andresen JH, Carlsen B, Solberg R, Mørkrid L, Goverud IL, Løberg EM, Saugstad OD (2009)
Newborn piglets exposed to hypoxia after nicotine or saline pretreatment: long-term effects on brain and heart
J Matern Fetal Neonatal Med, 22 (2), 161-8
PubMed 19253165

Andresen JH, Løberg EM, Wright M, Goverud IL, Stray-Pedersen B, Saugstad OD (2009)
Nicotine affects the expression of brain-derived neurotrophic factor mRNA and protein in the hippocampus of hypoxic newborn piglets
J Perinat Med, 37 (5), 553-60
PubMed 19492919

Babnik J, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP (2009)
Preface. Neonatology
Neonatology, 95 (4), 340-1
PubMed 19494554

Liu JQ, Saugstad OD, Cheung PY (2009)
Using 100% oxygen for the resuscitation of term neonates until evidence of spontaneous circulation: more investigations needed
Resuscitation, 81 (2), 145-7
PubMed 20036456

Maltepe E, Saugstad OD (2009)
Oxygen in health and disease: regulation of oxygen homeostasis--clinical implications
Pediatr Res, 65 (3), 261-8
PubMed 18852690

Odland HH, Kro GA, Edvardsen T, Thaulow E, Saugstad OD (2009)
Atrioventricular valve annulus velocity and acceleration during global hypoxia in newborn pigs - assessment of myocardial function
Neonatology, 97 (2), 100-7
PubMed 19713716

Sejersted Y, Aasland AL, Bjørås M, Eide L, Saugstad OD (2009)
Accumulation of 8-oxoguanine in liver DNA during hyperoxic resuscitation of newborn mice
Pediatr Res, 66 (5), 533-8
PubMed 19668103

Publications 2008

Andresen JH, Godang K, Munkeby BH, Stray-Pedersen B, Saugstad OD (2008)
Nicotine in a small-to-moderate dose does not cause a significant increase in plasma catecholamine levels in newborn piglets
Neonatology, 94 (4), 279-83
PubMed 18784424

Andresen JH, Saugstad OD (2008)
Effects of nicotine infusion on striatal glutamate and cortical non-protein-bound iron in hypoxic newborn piglets
Neonatology, 94 (4), 284-92
PubMed 18784425

Dalen ML, Frøyland E, Saugstad OD, Mollnes TE, Rootwelt T (2008)
Post-hypoxic hypothermia is protective in human NT2-N neurons regardless of oxygen concentration during reoxygenation
Brain Res, 1259, 80-9
PubMed 19146835

Garmany TH, Wambach JA, Heins HB, Watkins-Torry JM, Wegner DJ, Bennet K, An P, Land G, Saugstad OD, Henderson H, Nogee LM, Cole FS, Hamvas A (2008)
Population and disease-based prevalence of the common mutations associated with surfactant deficiency
Pediatr Res, 63 (6), 645-9
PubMed 18317237

Haumont D, Curstedt T, Halliday HL, Robertson B, Saugstad OD, Speer CP (2008)
Neonatology. Preface
Neonatology, 93 (4), 282-3
PubMed 18540132

Helland IB, Smith L, Blomén B, Saarem K, Saugstad OD, Drevon CA (2008)
Effect of supplementing pregnant and lactating mothers with n-3 very-long-chain fatty acids on children's IQ and body mass index at 7 years of age
Pediatrics, 122 (2), e472-9
PubMed 18676533

Lie RT, Wilcox AJ, Taylor J, Gjessing HK, Saugstad OD, Aabyholm F, Vindenes H (2008)
Maternal smoking and oral clefts: the role of detoxification pathway genes
Epidemiology, 19 (4), 606-15
PubMed 18449058

McBee AD, Wegner DJ, Carlson CS, Wambach JA, Yang P, Heins HB, Saugstad OD, Trusgnich MA, Watkins-Torry J, Nogee LM, Henderson H, Cole FS, Hamvas A (2008)
Recombination as a mechanism for sporadic mutation in the surfactant protein-C gene
Pediatr Pulmonol, 43 (5), 443-50
PubMed 18383112

Mollnes TE, Castellheim A, Lindenskov PH, Salvesen B, Saugstad OD (2008)
The role of complement in meconium aspiration syndrome
J Perinatol, 28 Suppl 3, S116-9
PubMed 19057601

Salvesen B, Fung M, Saugstad OD, Mollnes TE (2008)
Role of complement and CD14 in meconium-induced cytokine formation
Pediatrics, 121 (3), e496-505
PubMed 18299306

Salvesen B, Mollnes TE, Saugstad OD (2008)
Albumin lavage does not improve the outcome of meconium aspiration syndrome
J Matern Fetal Neonatal Med, 21 (10), 719-25
PubMed 19012188

Salvesen B, Nielsen EW, Harboe M, Saugstad OD, Mollnes TE (2008)
Mechanisms of complement activation and effects of C1-inhibitor on the meconium-induced inflammatory reaction in human cord blood
Mol Immunol, 46 (4), 688-94
PubMed 18950866

Saugstad OD (2008)
To oxygenate or not to oxygenate--that is the question
Am J Physiol Heart Circ Physiol, 295 (4), H1371-2
PubMed 18708440

Saugstad OD, Ramji S, Soll RF, Vento M (2008)
Resuscitation of newborn infants with 21% or 100% oxygen: an updated systematic review and meta-analysis
Neonatology, 94 (3), 176-82
PubMed 18612215

Saugstad OD, Tølløfsrud PA, Lindenskov P, Drevon CA (2008)
Toxic effects of different meconium fractions on lung function: new therapeutic strategies for meconium aspiration syndrome?
J Perinatol, 28 Suppl 3, S113-5
PubMed 19057600

Publications 2007

Andresen JH, Solberg R, Løberg EM, Munkeby BH, Stray-Pedersen B, Saugstad OD (2007)
Resuscitation with 21 or 100% oxygen in hypoxic nicotine-pretreated newborn piglets: possible neuroprotective effects of nicotine
Neonatology, 93 (1), 36-44
PubMed 17630496

Dohlen G, Odland HH, Carlsen H, Blomhoff R, Thaulow E, Saugstad OD (2007)
Antioxidant activity in the newborn brain: a luciferase mouse model
Neonatology, 93 (2), 125-31
PubMed 17785990

Kolas T, Saugstad OD, Daltveit AK, Nilsen ST, Oian P (2007)
Planned cesarean vs planned vaginal delivery at term - Reply
Am. J. Obstet. Gynecol., 197 (2), 217

Markus T, Hansson S, Amer-Wåhlin I, Hellström-Westas L, Saugstad OD, Ley D (2007)
Cerebral inflammatory response after fetal asphyxia and hyperoxic resuscitation in newborn sheep
Pediatr Res, 62 (1), 71-7
PubMed 17519806

Saugstad OD (2007)
Take a breath--but do not add oxygen (if not needed)
Acta Paediatr, 96 (6), 798-800
PubMed 17537006

Saugstad OD (2007)
New guidelines for newborn resuscitation
Acta Paediatr, 96 (3), 333-7
PubMed 17407451

Saugstad OD (2007)
Optimal oxygenation at birth and in the neonatal period
Neonatology, 91 (4), 319-22
PubMed 17575477

Saugstad OD, Hansen TW, Rønnestad A, Nakstad B, Tølløfsrud PA, Reinholt F, Hamvas A, Coles FS, Dean M, Wert SE, Whitsett JA, Nogee LM (2007)
Novel mutations in the gene encoding ATP binding cassette protein member A3 (ABCA3) resulting in fatal neonatal lung disease
Acta Paediatr, 96 (2), 185-90
PubMed 17429902

Saugstad OD, Ramji S, Vento M (2007)
The need to assess benefits and not just risks of 100% oxygen for newborn resuscitation - Reply
Pediatrics, 119 (1), 217-219

Solberg R, Andresen JH, Escrig R, Vento M, Saugstad OD (2007)
Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation
Pediatr Res, 62 (5), 559-63
PubMed 18049371

Sweet D, Bevilacqua G, Carnielli V, Greisen G, Plavka R, Saugstad OD, Simeoni U, Speer CP, Valls-I-Soler A, Halliday H, Working Group on Prematurity of the World Association of Perinatal Medicine, European Association of Perinatal Medicine (2007)
European consensus guidelines on the management of neonatal respiratory distress syndrome
J Perinat Med, 35 (3), 175-86
PubMed 17480144

Publications 2006

Børke WB, Edvardsen T, Fugelseth D, Lenes K, Ihlen H, Saugstad OD, Thaulow E (2006)
Reduced left ventricular function in hypoxemic newborn pigs: a strain Doppler echocardiographic study
Pediatr Res, 59 (5), 630-5
PubMed 16627872

Gonzalez R, Merialdi M, Lincetto O, Lauer J, Becerra C, Castro R, García P, Saugstad OD, Villar J (2006)
Reduction in neonatal mortality in Chile between 1990 and 2000
Pediatrics, 117 (5), e949-54
PubMed 16606682

Helland IB, Saugstad OD, Saarem K, Van Houwelingen AC, Nylander G, Drevon CA (2006)
Supplementation of n-3 fatty acids during pregnancy and lactation reduces maternal plasma lipid levels and provides DHA to the infants
J Matern Fetal Neonatal Med, 19 (7), 397-406
PubMed 16923694

Hellström-Westas L, Forsblad K, Sjörs G, Saugstad OD, Björklund LJ, Marsál K, Källén K (2006)
Earlier Apgar score increase in severely depressed term infants cared for in Swedish level III units with 40% oxygen versus 100% oxygen resuscitation strategies: a population-based register study
Pediatrics, 118 (6), e1798-804
PubMed 17142501

Kolås T, Saugstad OD, Daltveit AK, Nilsen ST, Øian P (2006)
Planned cesarean versus planned vaginal delivery at term: comparison of newborn infant outcomes
Am J Obstet Gynecol, 195 (6), 1538-43
PubMed 16846577

Lyng K, Munkeby BH, Scheie D, Mallard C, Hagberg H, Stray-Pedersen B, Saugstad OD, Frøen JF (2006)
Fetal brain injury in experimental intrauterine asphyxia and inflammation in Göttingen minipigs
J Perinat Med, 34 (3), 226-34
PubMed 16602844

Saugstad OD (2006)
Oxygen and retinopathy of prematurity
J Perinatol, 26 Suppl 1, S46-50; discussion S63-4
PubMed 16482198

Saugstad OD (2006)
Some like it cool: hypothermia for newborn infants with hypoxic ischemic encephalopathy
J Perinatol, 26 (3), 144-6
PubMed 16493431

Saugstad OD (2006)
Oxygen saturations immediately after birth
J Pediatr, 148 (5), 569-70
PubMed 16737860

Saugstad OD (2006)
Non-selective fetal reduction is malpractice
J Perinat Med, 34 (5), 355-8
PubMed 16965220

Saugstad OD, Ramji S, Vento M (2006)
Oxygen for newborn resuscitation: how much is enough?
Pediatrics, 118 (2), 789-92
PubMed 16882835

Vento Torres M, Saugstad OD, Ramji S (2006)
[Normoxemic resuscitation in the delivery room]
An Pediatr (Barc), 64 (5), 419-21
PubMed 16756881

Publications 2005

Castellheim A, Lindenskov PH, Pharo A, Aamodt G, Saugstad OD, Mollnes TE (2005)
Meconium aspiration syndrome induces complement-associated systemic inflammatory response in newborn piglets
Scand J Immunol, 61 (3), 217-25
PubMed 15787738

Døhlen G, Carlsen H, Blomhoff R, Thaulow E, Saugstad OD (2005)
Reoxygenation of hypoxic mice with 100% oxygen induces brain nuclear factor-kappa B
Pediatr Res, 58 (5), 941-5
PubMed 16183808

Fallang B, Øien I, Hellem E, Saugstad OD, Hadders-Algra M (2005)
Quality of reaching and postural control in young preterm infants is related to neuromotor outcome at 6 years
Pediatr Res, 58 (2), 347-53
PubMed 16055930

Fugelseth D, Børke WB, Lenes K, Matthews I, Saugstad OD, Thaulow E (2005)
Restoration of cardiopulmonary function with 21% versus 100% oxygen after hypoxaemia in newborn pigs
Arch Dis Child Fetal Neonatal Ed, 90 (3), F229-34
PubMed 15846013

Haavet OR, Saugstad OD, Straand J (2005)
Positive factors associated with promoting health in low-risk and high-risk populations of 15- and 16-year-old pupils in Oslo, Norway
Acta Paediatr, 94 (3), 345-51
PubMed 16028654

Haavet OR, Straand J, Hjortdahl P, Saugstad OD (2005)
Do negative life experiences predict the health-care-seeking of adolescents? A study of 10th-year students in Oslo, Norway
J Adolesc Health, 37 (2), 128-34
PubMed 16026722

Lindenskov PH, Castellheim A, Aamodt G, Saugstad OD (2005)
Meconium induced IL-8 production and intratracheal albumin alleviated lung injury in newborn pigs
Pediatr Res, 57 (3), 371-7
PubMed 15635049

Lyng K, Braakhuis M, Frøen JF, Stray-Pedersen B, Saugstad OD (2005)
Inflammation increases vulnerability to hypoxia in newborn piglets: effect of reoxygenation with 21% and 100% O2
Am J Obstet Gynecol, 192 (4), 1172-8
PubMed 15846198

Lyng K, Munkeby BH, Saugstad OD, Stray-Pedersen B, Frøen JF (2005)
Effect of interleukin-10 on newborn piglet brain following hypoxia-ischemia and endotoxin-induced inflammation
Biol Neonate, 87 (3), 207-16
PubMed 15637455

Munkeby BH, Børke WB, Bjørnland K, Sikkeland LI, Borge GI, Lømo J, Rivera S, Khrestchatisky M, Halvorsen B, Saugstad OD (2005)
Resuscitation of hypoxic piglets with 100% O2 increases pulmonary metalloproteinases and IL-8
Pediatr Res, 58 (3), 542-8
PubMed 16148071

Saugstad OD (2005)
[Should some newborn infants not be treated?]
Tidsskr Nor Laegeforen, 125 (10), 1308
PubMed 15908997

Saugstad OD (2005)
When newborn infants are bound to die
Acta Paediatr, 94 (11), 1535-7
PubMed 16303690

Saugstad OD (2005)
Oxygen for newborns: how much is too much?
J Perinatol, 25 Suppl 2, S45-9; discussion S50
PubMed 15861173

Saugstad OD (2005)
Oxidative stress in the newborn--a 30-year perspective
Biol Neonate, 88 (3), 228-36
PubMed 16210845

Saugstad OD, Ramji S, Rootwelt T, Vento M (2005)
Response to resuscitation of the newborn: early prognostic variables
Acta Paediatr, 94 (7), 890-5
PubMed 16188811

Publications 2004

Borke WB, Munkeby BH, Halvorsen B, Bjornland K, Tunheim SH, Borge GI, Thaulow E, Saugstad OD (2004)
Increased myocardial matrix metalloproteinases in hypoxic newborn pigs during resuscitation: effects of oxygen and carbon dioxide
Eur J Clin Invest, 34 (7), 459-66
PubMed 15255782

Børke WB, Munkeby BH, Mørkrid L, Thaulow E, Saugstad OD (2004)
Resuscitation with 100% O(2) does not protect the myocardium in hypoxic newborn piglets
Arch Dis Child Fetal Neonatal Ed, 89 (2), F156-60
PubMed 14977902

Castellheim A, Pharo A, Fung M, Saugstad OD, Mollnes TE (2004)
Complement C5a is a key mediator of meconium-induced neutrophil activation
Pediatr Res, 57 (2), 242-7
PubMed 15585680

Haavet OR, Straand J, Saugstad OD, Grünfeld B (2004)
Illness and exposure to negative life experiences in adolescence: two sides of the same coin? A study of 15-year-olds in Oslo, Norway
Acta Paediatr, 93 (3), 405-11
PubMed 15124848

Lindenskov PH, Castellheim A, Aamodt G, Saugstad OD, Mollnes TE (2004)
Complement activation reflects severity of meconium aspiration syndrome in newborn pigs
Pediatr Res, 56 (5), 810-7
PubMed 15347770

Munkeby BH, Børke WB, Bjørnland K, Sikkeland LI, Borge GI, Halvorsen B, Saugstad OD (2004)
Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets
Pediatr Res, 56 (5), 783-90
PubMed 15347772

Munkeby BH, Lyng K, Frøen JF, Winther-Larssen EH, Rosland JH, Smith HJ, Saugstad OD, Bjørnerud A (2004)
Morphological and hemodynamic magnetic resonance assessment of early neonatal brain injury in a piglet model
J Magn Reson Imaging, 20 (1), 8-15
PubMed 15221803

Saugstad OD (2004)
The role of oxygen in neonatal resuscitation
Clin Perinatol, 31 (3), 431-43
PubMed 15325530

Saugstad OD (2004)
Optimal oxygen therapy in the newborn period
Pediatr Pulmonol Suppl, 26, 112-3
PubMed 15029619

Saugstad OD (2004)
Resuscitation with pure oxygen at birth: it is time for a change
J Matern Fetal Neonatal Med, 15 (2), 73-4
PubMed 15209112

Saugstad OD (2004)
[How fast should premature infants grow?]
Tidsskr Nor Laegeforen, 124 (5), 615
PubMed 15004600

Saugstad OD (2004)
Room air resuscitation-two decades of neonatal research
Early Hum Dev, 81 (1), 111-6
PubMed 15707722

Saugstad OD, Ramji S, Vento M (2004)
Resuscitation of depressed newborn infants with ambient air or pure oxygen: a meta-analysis
Biol Neonate, 87 (1), 27-34
PubMed 15452400

Saugstad OD, Rootwelt T (2004)
[Children as research subjects]
Tidsskr Nor Laegeforen, 124 (8), 1141; author reply 1141-2
PubMed 15114401

Solas AB, Munkeby BH, Saugstad OD (2004)
Comparison of short- and long-duration oxygen treatment after cerebral asphyxia in newborn piglets
Pediatr Res, 56 (1), 125-31
PubMed 15128930

Tølløfsrud PA, Medbø S, Solås AB, Robertson B, Speer CP, Seidenspinner S, Drevon CA, Saugstad OD (2004)
Intratracheal albumin reduces interleukin-8 in tracheobronchial aspirates in piglets after meconium aspiration
J Perinat Med, 32 (1), 78-83
PubMed 15008393

Publications 2003

Almaas R, Pytte M, Lindstad JK, Wright M, Saugstad OD, Pleasure D, Rootwelt T (2003)
Acidosis has opposite effects on neuronal survival during hypoxia and reoxygenation
J Neurochem, 84 (5), 1018-27
PubMed 12603826

Castellheim A, Lindenskov PH, Pharo A, Fung M, Saugstad OD, Mollnes TE (2003)
Meconium is a potent activator of complement in human serum and in piglets
Pediatr Res, 55 (2), 310-8
PubMed 14605246

Fallang B, Saugstad OD, Grøgaard J, Hadders-Algra M (2003)
Kinematic quality of reaching movements in preterm infants
Pediatr Res, 53 (5), 836-42
PubMed 12612201

Fallang B, Saugstad OD, Hadders-Algra M (2003)
Postural adjustments in preterm infants at 4 and 6 months post-term during voluntary reaching in supine position
Pediatr Res, 54 (6), 826-33
PubMed 12904588

Helland IB, Smith L, Saarem K, Saugstad OD, Drevon CA (2003)
Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age
Pediatrics, 111 (1), e39-44
PubMed 12509593

Jugessur A, Lie RT, Wilcox AJ, Murray JC, Taylor JA, Saugstad OD, Vindenes HA, Abyholm F (2003)
Variants of developmental genes (TGFA, TGFB3, and MSX1) and their associations with orofacial clefts: a case-parent triad analysis
Genet Epidemiol, 24 (3), 230-9
PubMed 12652527

Jugessur A, Lie RT, Wilcox AJ, Murray JC, Taylor JA, Saugstad OD, Vindenes HA, Abyholm FE (2003)
Cleft palate, transforming growth factor alpha gene variants, and maternal exposures: assessing gene-environment interactions in case-parent triads
Genet Epidemiol, 25 (4), 367-74
PubMed 14639706

Saugstad OD (2003)
Bronchopulmonary dysplasia-oxidative stress and antioxidants
Semin Neonatol, 8 (1), 39-49
PubMed 12667829

Saugstad OD (2003)
Protect the innocent!
J Matern Fetal Neonatal Med, 13 (1), 1
PubMed 12710850

Saugstad OD (2003)
Surfactant therapy is still on the move
J Matern Fetal Neonatal Med, 14 (3), 145-6
PubMed 14694967

Saugstad OD (2003)
[Clinical medical research--from wrong to worse?]
Tidsskr Nor Laegeforen, 123 (2), 142
PubMed 12607490

Saugstad OD (2003)
Fetal reduction: a neonatologist's point of view
J Matern Fetal Neonatal Med, 13 (5), 289-91
PubMed 12916676

Saugstad OD (2003)
[From the informed to the administrative autocracy]
Tidsskr Nor Laegeforen, 123 (12), 1732
PubMed 12821997

Saugstad OD, Ramji S, Irani SF, El-Meneza S, Hernandez EA, Vento M, Talvik T, Solberg R, Rootwelt T, Aalen OO (2003)
Resuscitation of newborn infants with 21% or 100% oxygen: follow-up at 18 to 24 months
Pediatrics, 112 (2), 296-300
PubMed 12897277

Solås AB, Kalous P, Davis JM, Saugstad OD (2003)
Effects of recombinant human superoxide dismutase during reoxygenation with 21% or 100% oxygen after cerebral asphyxia in newborn piglets
J Matern Fetal Neonatal Med, 14 (2), 96-101
PubMed 14629089

Solås AB, Kalous P, Saugstad OD (2003)
Reoxygenation with 100 or 21% oxygen after cerebral hypoxemia-ischemia-hypercapnia in newborn piglets
Biol Neonate, 85 (2), 105-11
PubMed 14631156

Truffert P, Empana JP, Bréart G, Saugstad OD, Goelz R, Halliday HL, Anceschi M (2003)
Treatment strategies for bronchopulmonary dysplasia with postnatal corticosteroids in Europe: the EURAIL survey
Acta Paediatr, 92 (8), 948-51
PubMed 12948071

Tølløfsrud PA, Lindenskov PH, Drevon CA, Speer CP, Seidenspinner S, Saugstad OD (2003)
Comparison of pulmonary and inflammatory effects of lipid- and water-soluble components in meconium in newborn piglets
Biol Neonate, 84 (4), 330-7
PubMed 14593245

Publications 2002

Almaas R, Saugstad OD, Pleasure D, Rootwelt T (2002)
Neuronal formation of free radicals plays a minor role in hypoxic cell death in human NT2-N neurons
Pediatr Res, 51 (2), 136-43
PubMed 11809906

Frøen JF, Akre H, Stray-Pedersen B, Saugstad OD (2002)
Prolonged apneas and hypoxia mediated by nicotine and endotoxin in piglets
Biol Neonate, 81 (2), 119-25
PubMed 11844882

Frøen JF, Amerio G, Stray-Pedersen B, Saugstad OD (2002)
Detrimental effects of nicotine and endotoxin in the newborn piglet brain during severe hypoxemia
Biol Neonate, 82 (3), 188-96
PubMed 12373070

Frøen JF, Arnestad M, Vege A, Irgens LM, Rognum TO, Saugstad OD, Stray-Pedersen B (2002)
Comparative epidemiology of sudden infant death syndrome and sudden intrauterine unexplained death
Arch Dis Child Fetal Neonatal Ed, 87 (2), F118-21
PubMed 12193518

Frøen JF, Munkeby BH, Stray-Pedersen B, Saugstad OD (2002)
Interleukin-10 reverses acute detrimental effects of endotoxin-induced inflammation on perinatal cerebral hypoxia-ischemia
Brain Res, 942 (1-2), 87-94
PubMed 12031856

Frøen JF, Møyland RA, Saugstad OD, Stray-Pedersen B (2002)
Maternal health in sudden intrauterine unexplained death: do urinary tract infections protect the fetus?
Obstet Gynecol, 100 (5 Pt 1), 909-15
PubMed 12423852

Kutzsche S, Solas AB, Lyberg T, Saugstad OD (2002)
Nitric oxide synthesis inhibition during cerebral hypoxemia and reoxygenation with 100% oxygen in newborn pigs
Biol Neonate, 82 (3), 197-206
PubMed 12373071

Saugstad OD (2002)
New guidelines for resuscitation of the newly born infant
J Matern Fetal Neonatal Med, 11 (1), 2-3
PubMed 12380600

Saugstad OD (2002)
Is lactate a reliable indicator of tissue hypoxia in the neonatal period?
Acta Paediatr, 91 (1), 17-9
PubMed 11883813

Tølløfsrud PA, Medbø S, Solas AB, Drevon CA, Saugstad OD (2002)
Albumin mixed with meconium attenuates pulmonary dysfunction in a newborn piglet model with meconium aspiration
Pediatr Res, 52 (4), 545-53
PubMed 12357049

Publications 2001

Frøen JF, Arnestad M, Frey K, Vege A, Saugstad OD, Stray-Pedersen B (2001)
Risk factors for sudden intrauterine unexplained death: epidemiologic characteristics of singleton cases in Oslo, Norway, 1986-1995
Am J Obstet Gynecol, 184 (4), 694-702
PubMed 11262474

Helland IB, Reseland JE, Saugstad OD, Drevon CA (2001)
Smoking related to plasma leptin concentration in pregnant women and their newborn infants
Acta Paediatr, 90 (3), 282-7
PubMed 11332168

Helland IB, Saugstad OD, Smith L, Saarem K, Solvoll K, Ganes T, Drevon CA (2001)
Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women
Pediatrics, 108 (5), E82
PubMed 11694666

Kutzsche S, Ilves P, Kirkeby OJ, Saugstad OD (2001)
Hydrogen peroxide production in leukocytes during cerebral hypoxia and reoxygenation with 100% or 21% oxygen in newborn piglets
Pediatr Res, 49 (6), 834-42
PubMed 11385146

Medbø S, Frøen JF, Saugstad OD (2001)
Effects of selective inhibition of the endothelin A and B receptors on hypoxic pulmonary vasoconstriction in newborn piglets
J Perinat Med, 29 (4), 344-50
PubMed 11565204

Niermeyer S, Van Reempts P, Kattwinkel J, Wiswell T, Burchfield D, Saugstad OD, Milner A, Knaebel S, Perlman J, Azzopardi D, Gunn A, Boyle R, Toce S, Solimano A, American Heart Association, International Liaison Committee on Resuscitation (2001)
Resuscitation of newborns
Ann Emerg Med, 37 (4 Suppl), S110-25
PubMed 11290975

Saugstad OD (2001)
Chronic lung disease: oxygen dogma revisited
Acta Paediatr, 90 (2), 113-5
PubMed 11236035

Saugstad OD (2001)
Update on oxygen radical disease in neonatology
Curr Opin Obstet Gynecol, 13 (2), 147-53
PubMed 11315869

Saugstad OD (2001)
Is oxygen more toxic than currently believed?
Pediatrics, 108 (5), 1203-5
PubMed 11694702

Saugstad OD (2001)
Resuscitation of newborn infants with room air or oxygen
Semin Neonatol, 6 (3), 233-9
PubMed 11520188

Saugstad OD (2001)
Resuscitation of the asphyxic newborn infant: new insight leads to new therapeutic possibilities
Biol Neonate, 79 (3-4), 258-60
PubMed 11275662

Skaug MA, Helland I, Solvoll K, Saugstad OD (2001)
Presence of ochratoxin A in human milk in relation to dietary intake
Food Addit Contam, 18 (4), 321-7
PubMed 11339267

Solås AB, Kutzsche S, Vinje M, Saugstad OD (2001)
Cerebral hypoxemia-ischemia and reoxygenation with 21% or 100% oxygen in newborn piglets: effects on extracellular levels of excitatory amino acids and microcirculation
Pediatr Crit Care Med, 2 (4), 340-5
PubMed 12793938

Tølløfsrud PA, Solås AB, Saugstad OD (2001)
Newborn piglets with meconium aspiration resuscitated with room air or 100% oxygen
Pediatr Res, 50 (3), 423-9
PubMed 11518832

Publications 2000

Almaas R, Robertson B, Linderholm B, Lundberg E, Saugstad OD, Moen A (2000)
Reversal of meconium inhibition of pulmonary surfactant by ferric chloride, copper chloride, and acetic acid
Am J Respir Crit Care Med, 162 (5), 1789-94
PubMed 11069814

Almaas R, Saugstad OD, Pleasure D, Rootwelt T (2000)
Effect of barbiturates on hydroxyl radicals, lipid peroxidation, and hypoxic cell death in human NT2-N neurons
Anesthesiology, 92 (3), 764-74
PubMed 10719955

Cinek O, Wilkinson E, Paltiel L, Saugstad OD, Magnus P, Rønningen KS (2000)
Screening for the IDDM high-risk genotype. A rapid microtitre plate method using serum as source of DNA
Tissue Antigens, 56 (4), 344-9
PubMed 11098934

Fallang B, Saugstad OD, Hadders-Algra M (2000)
Goal directed reaching and postural control in supine position in healthy infants
Behav Brain Res, 115 (1), 9-18
PubMed 10996403

Frøen JF, Akre H, Stray-Pedersen B, Saugstad OD (2000)
Adverse effects of nicotine and interleukin-1beta on autoresuscitation after apnea in piglets: implications for sudden infant death syndrome
Pediatrics, 105 (4), E52
PubMed 10742373

Niermeyer S, Kattwinkel J, Van Reempts P, Nadkarni V, Phillips B, Zideman D, Azzopardi D, Berg R, Boyle D, Boyle R, Burchfield D, Carlo W, Chameides L, Denson S, Fallat M, Gerardi M, Gunn A, Hazinski MF, Keenan W, Knaebel S, Milner A, Perlman J, Saugstad OD, Schleien C, Solimano A et al. (2000)
International Guidelines for Neonatal Resuscitation: An excerpt from the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: International Consensus on Science. Contributors and Reviewers for the Neonatal Resuscitation Guidelines
Pediatrics, 106 (3), E29
PubMed 10969113

Saugstad OD (2000)
Does nitric oxide prevent oxidative mediated lung injury?
Acta Paediatr, 89 (8), 905-7
PubMed 10976827

Saugstad OD, Rootwelt T, Aalen OO (2000)
[Resuscitation of newborn infants with room air or oxygen]
Tidsskr Nor Laegeforen, 120 (1), 25-8
PubMed 10815474

Publications 1999

Kutzsche S, Kirkeby OJ, Rise IR, Saugstad OD (1999)
Effects of hypoxia and reoxygenation with 21% and 100%-oxygen on cerebral nitric oxide concentration and microcirculation in newborn piglets
Biol Neonate, 76 (3), 153-67
PubMed 10460953

Medbø S, Tølløfsrud PA, Saugstad OD (1999)
Pulmonary hemodynamics in newborn piglets during hypoxemia and reoxygenation: blocking of the endothelin-1 receptors
Pediatr Res, 46 (5), 514-22
PubMed 10541312

Rødningen OK, Tonstad S, Saugstad OD, Ose L, Leren TP (1999)
Mutant transcripts of the LDL receptor gene: mRNA structure and quantity
Hum Mutat, 13 (3), 186-96
PubMed 10090473

Saugstad OD (1999)
Inhaled nitric oxide for preterm infants--still an experimental therapy
Lancet, 354 (9184), 1047-8
PubMed 10509489

Saugstad OD (1999)
[Postnatal steroid treatment--time to reconsider?]
Tidsskr Nor Laegeforen, 119 (23), 3404
PubMed 10553333

Storm H, Nylander G, Saugstad OD (1999)
The amount of brainstem gliosis in sudden infant death syndrome (SIDS) victims correlates with maternal cigarette smoking during pregnancy
Acta Paediatr, 88 (1), 13-8
PubMed 10090540

Yu XQ, Medbo S, Saugstad OD (1999)
Sodium nitroprusside prevents oxygen-free-radical-induced pulmonary vasoconstriction in newborn piglets
Biol Neonate, 75 (5), 319-26
PubMed 10095146

Yu XQ, Saugstad OD (1999)
Nebulization of sodium nitroprusside in lung-lavaged newborn piglets
Pediatr Res, 45 (2), 255-9
PubMed 10022599

Publications 1998

Elsner R, Oyasaeter S, Almaas R, Saugstad OD (1998)
Diving seals, ischemia-reperfusion and oxygen radicals
Comp Biochem Physiol A Mol Integr Physiol, 119 (4), 975-80
PubMed 9773490

Feet BA, Brun NC, Hellström-Westas L, Svenningsen NW, Greisen G, Saugstad OD (1998)
Early cerebral metabolic and electrophysiological recovery during controlled hypoxemic resuscitation in piglets
J Appl Physiol (1985), 84 (4), 1208-16
PubMed 9516186

Feet BA, Gilland E, Groenendaal F, Brun NC, Hellström-Westas L, Hagberg H, Saugstad OD (1998)
Cerebral excitatory amino acids and Na+,K+-ATPase activity during resuscitation of severely hypoxic newborn piglets
Acta Paediatr, 87 (8), 889-95
PubMed 9736239

Feet BA, Medbö S, Rootwelt T, Ganes T, Saugstad OD (1998)
Hypoxemic resuscitation in newborn piglets: recovery of somatosensory evoked potentials, hypoxanthine, and acid-base balance
Pediatr Res, 43 (5), 690-6
PubMed 9585017

Helland IB, Reseland JE, Saugstad OD, Drevon CA (1998)
Leptin levels in pregnant women and newborn infants: gender differences and reduction during the neonatal period
Pediatrics, 101 (3), E12
PubMed 9481031

Helland IB, Saarem K, Saugstad OD, Drevon CA (1998)
Fatty acid composition in maternal milk and plasma during supplementation with cod liver oil
Eur J Clin Nutr, 52 (11), 839-45
PubMed 9846598

Medbø S, Yu XQ, Asberg A, Saugstad OD (1998)
Pulmonary hemodynamics and plasma endothelin-1 during hypoxemia and reoxygenation with room air or 100% oxygen in a piglet model
Pediatr Res, 44 (6), 843-9
PubMed 9853916

Moen A, Yu XQ, Almaas R, Curstedt T, Saugstad OD (1998)
Acute effects on systemic circulation after intratracheal instillation of Curosurf or Survanta in surfactant-depleted newborn piglets
Acta Paediatr, 87 (3), 297-303
PubMed 9560037

Opdal SH, Rognum TO, Vege A, Saugstad OD (1998)
Hypoxanthine levels in vitreous humor: a study of influencing factors in sudden infant death syndrome
Pediatr Res, 44 (2), 192-6
PubMed 9702913

Saugstad OD (1998)
Practical aspects of resuscitating asphyxiated newborn infants
Eur J Pediatr, 157 Suppl 1, S11-5
PubMed 9462900

Saugstad OD (1998)
Chronic lung disease: the role of oxidative stress
Biol Neonate, 74 Suppl 1, 21-8
PubMed 9730588

Saugstad OD (1998)
Resuscitation with room-air or oxygen supplementation
Clin Perinatol, 25 (3), 741-56, xi
PubMed 9779345

Saugstad OD, Rootwelt T, Aalen O (1998)
Resuscitation of asphyxiated newborn infants with room air or oxygen: an international controlled trial: the Resair 2 study
Pediatrics, 102 (1), e1
PubMed 9651453

Skaug MA, Størmer FC, Saugstad OD (1998)
Ochratoxin A: a naturally occurring mycotoxin found in human milk samples from Norway
Acta Paediatr, 87 (12), 1275-8
PubMed 9894829

Vege A, Rognum TO, Aasen AO, Saugstad OD (1998)
Are elevated cerebrospinal fluid levels of IL-6 in sudden unexplained deaths, infectious deaths and deaths due to heart/lung disease in infants and children due to hypoxia?
Acta Paediatr, 87 (8), 819-24
PubMed 9736227

Yu XO, Moen A, Feet BA, Saugstad OD (1998)
Oxygen delivery and consumption in surfactant-depleted newborn piglets
Intensive Care Med, 24 (4), 358-62
PubMed 9609415

Publications 1997

Almaas R, Rootwelt T, Oyasaeter S, Saugstad OD (1997)
Ascorbic acid enhances hydroxyl radical formation in iron-fortified infant cereals and infant formulas
Eur J Pediatr, 156 (6), 488-92
PubMed 9208249

Almaas R, Sundar TB, Rootwelt T, Oyasaeter S, Saugstad OD (1997)
Plasma hypoxanthine reacts more abruptly to changes in oxygenation than base deficit and uric acid in newborn piglets
J Perinat Med, 25 (4), 353-60
PubMed 9350606

Brun NC, Moen A, Børch K, Saugstad OD, Greisen G (1997)
Near-infrared monitoring of cerebral tissue oxygen saturation and blood volume in newborn piglets
Am J Physiol, 273 (2 Pt 2), H682-6
PubMed 9277484

Feet BA, Yu XQ, Rootwelt T, Oyasaeter S, Saugstad OD (1997)
Effects of hypoxemia and reoxygenation with 21% or 100% oxygen in newborn piglets: extracellular hypoxanthine in cerebral cortex and femoral muscle
Crit Care Med, 25 (8), 1384-91
PubMed 9267954

Harkness RA, Saugstad OD (1997)
The importance of the measurement of ATP depletion and subsequent cell damage with an estimate of size and nature of the market for a practicable method: a review designed for technology transfer
Scand J Clin Lab Invest, 57 (8), 655-72
PubMed 9458488

Moen A, Yu XQ, Rootwelt T, Saugstad OD (1997)
Acute effects on systemic and pulmonary hemodynamics of intratracheal instillation of porcine surfactant or saline in surfactant-depleted newborn piglets
Pediatr Res, 41 (4 Pt 1), 486-92
PubMed 9098849

Saugstad OD (1997)
Bronchopulmonary dysplasia and oxidative stress: are we closer to an understanding of the pathogenesis of BPD?
Acta Paediatr, 86 (12), 1277-82
PubMed 9475300

Yu XQ, Feet BA, Moen A, Curstedt T, Saugstad OD (1997)
Nitric oxide contributes to surfactant-induced vasodilation in surfactant-depleted newborn piglets
Pediatr Res, 42 (2), 151-6
PubMed 9262215

Publications 1996

Moen A, Rootwelt T, Robertson B, Curstedt T, Hall C, Saugstad OD (1996)
Hemodynamics and tissue blood flow after porcine surfactant replacement in surfactant-depleted newborn piglets
Pediatr Res, 40 (2), 215-24
PubMed 8827769

Rootwelt T, Odden JP, Hall C, Saugstad OD (1996)
Regional blood flow during severe hypoxemia and resuscitation with 21% or 100% O2 in newborn pigs
J Perinat Med, 24 (3), 227-36
PubMed 8827571

Saugstad OD (1996)
Mechanisms of tissue injury by oxygen radicals: implications for neonatal disease
Acta Paediatr, 85 (1), 1-4
PubMed 8834970

Saugstad OD (1996)
Role of xanthine oxidase and its inhibitor in hypoxia: reoxygenation injury
Pediatrics, 98 (1), 103-7
PubMed 8668378

Storm H, Stoltenberg L, Saugstad OD, Rognum TO, Reichelt KL (1996)
Beta-endorphin immunoreactivity levels in CSF after laryngeal chemoreflex activation correlate with apnoea duration in piglets
J Perinat Med, 24 (4), 363-72
PubMed 8880634

Publications 1995

Opdal SH, Vege A, Saugstad OD, Rognum TO (1995)
Is the medium-chain acyl-CoA dehydrogenase G985 mutation involved in sudden infant death in Norway?
Eur J Pediatr, 154 (2), 166-7
PubMed 7720752

Pettersen RD, Saugstad OD, Heyerdahl S, Motzfeldt K, Lie SO (1995)
[Screening of newborn infants in Norway for severe metabolic disease]
Tidsskr Nor Laegeforen, 115 (5), 584-7
PubMed 7900109

Pettersen RD, Saugstad OD, Lie SO (1995)
[Neonatal screening for metabolic diseases--a task without priority in the Norwegian health policy?]
Tidsskr Nor Laegeforen, 115 (5), 607-8
PubMed 7900116

Rootwelt T, Almaas R, Oyasaeter S, Moen A, Saugstad OD (1995)
Release of xanthine oxidase to the systemic circulation during resuscitation from severe hypoxemia in newborn pigs
Acta Paediatr, 84 (5), 507-11
PubMed 7633144

Sanderud J, Kumlin M, Granström E, Saugstad OD (1995)
Effects of oxygen radicals on cysteinyl leukotriene metabolism and pulmonary circulation in young pigs
Eur Surg Res, 27 (2), 117-26
PubMed 7781643

Sanderud J, Oroszlàn G, Bjøro K, Kumlin M, Saugstad OD (1995)
D-penicillamine inhibits the action of reactive oxygen species in the pig pulmonary circulation
J Perinat Med, 23 (5), 385-93
PubMed 8606345

Saugstad OD (1995)
[Treatment with high-frequency jet ventilators and nitrogen oxide in Norwegian neonatal practice]
Tidsskr Nor Laegeforen, 115 (5), 581-2
PubMed 7900107

Shinwell ES, Robertson B, Saugstad OD, Halliday HL, Speer CP (1995)
Update on surfactant therapy. Report from the 9th International Workshop on Surfactant Replacement, Jerusalem, May 22-25, 1994
Biol Neonate, 67 (1), 2-12
PubMed 7748970

Stoltenberg L, Vege A, Saugstad OD, Rognum TO (1995)
Changes in the concentration and distribution of immunoglobulin-producing cells in SIDS palatine tonsils
Pediatr Allergy Immunol, 6 (1), 48-55
PubMed 7550766

Storm H, Stoltenberg L, Oyasaeter S, Saugstad OD, Rognum TO, Reichelt KL (1995)
Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets
Pediatr Res, 38 (2), 205-10
PubMed 7478817

Vege A, Rognum TO, Scott H, Aasen AO, Saugstad OD (1995)
SIDS cases have increased levels of interleukin-6 in cerebrospinal fluid
Acta Paediatr, 84 (2), 193-6
PubMed 7756807

Publications 1994

Bell AH, Skov L, Lundstrøm KE, Saugstad OD, Greisen G (1994)
Cerebral blood flow and plasma hypoxanthine in relation to surfactant treatment
Acta Paediatr, 83 (9), 910-4
PubMed 7819684

Haberland A, Rootwelt T, Saugstad OD, Schimke I (1994)
Modulation of the xanthine oxidase/xanthine dehydrogenase ratio by reaction of malondialdehyde with NH2-groups
Eur J Clin Chem Clin Biochem, 32 (4), 267-72
PubMed 8038267

Opdal SH, Vege A, Saugstad OD, Rognum TO (1994)
Is partial deletion of the complement C4 genes associated with sudden infant death?
Eur J Pediatr, 153 (4), 287-90
PubMed 8194566

Robertson B, Saugstad OD (1994)
[Natural or synthetic surfactant in the treatment of neonatal respiratory distress syndrome]
Tidsskr Nor Laegeforen, 114 (8), 987-8
PubMed 8191480

Saugstad OD (1994)
[Questionable guidelines on solid food to breast-fed infants]
Tidsskr Nor Laegeforen, 114 (30), 3704-5
PubMed 7825156

Saugstad OD (1994)
[Neonatology in India]
Tidsskr Nor Laegeforen, 114 (17), 2015-7
PubMed 8079335

Saugstad OD, Aasen AO (1994)
Free radicals and antioxidants
Lancet, 344 (8934), 1442
PubMed 7968108

Stoltenberg L, Sundar T, Almaas R, Storm H, Rognum TO, Saugstad OD (1994)
Changes in apnea and autoresuscitation in piglets after intravenous and intrathecal interleukin-1 beta injection
J Perinat Med, 22 (5), 421-32
PubMed 7791018

Storm H, Rognum TO, Saugstad OD, Skullerud K, Reichelt KL (1994)
Beta-endorphin immunoreactivity in spinal fluid and hypoxanthine in vitreous humour related to brain stem gliosis in sudden infant death victims
Eur J Pediatr, 153 (9), 675-81
PubMed 7957429

Vege A, Chen Y, Opdal SH, Saugstad OD, Rognum TO (1994)
Vitreous humor hypoxanthine levels in SIDS and infectious death
Acta Paediatr, 83 (6), 634-9
PubMed 7919762

Publications 1993

Bechensteen AG, Hågå P, Halvorsen S, Whitelaw A, Liestøl K, Lindemann R, Grøgaard J, Hellebostad M, Saugstad OD, Grønn M (1993)
Erythropoietin, protein, and iron supplementation and the prevention of anaemia of prematurity
Arch Dis Child, 69 (1 Spec No), 19-23
PubMed 8346946

Blomhoff R, Botten G, Baerug A, Saugstad OD, Bjørneboe GE (1993)
[Recommendations of the Council for Nutrition on infant nutrition. Norwegian National Nutrition Council]
Tidsskr Nor Laegeforen, 113 (27), 3368-73
PubMed 8273065

Poulsen JP, Lun A, Scheuch C, Gruetzmann H, Saugstad OD, Gross J (1993)
Effect of the hypoxanthine/xanthine oxidase system on dopamine outflow from rat striatal synaptosomes
Neuropediatrics, 24 (1), 30-5
PubMed 8474608

Poulsen JP, Oyasaeter S, Saugstad OD (1993)
Hypoxanthine, xanthine, and uric acid in newborn pigs during hypoxemia followed by resuscitation with room air or 100% oxygen
Crit Care Med, 21 (7), 1058-65
PubMed 8319464

Poulsen JP, Rognum TO, Hauge S, Oyasaeter S, Saugstad OD (1993)
Post-mortem concentrations of hypoxanthine in the vitreous humor--a comparison between babies with severe respiratory failure, congenital abnormalities of the heart, and victims of sudden infant death syndrome
J Perinat Med, 21 (2), 153-63
PubMed 8515358

Ramji S, Ahuja S, Thirupuram S, Rootwelt T, Rooth G, Saugstad OD (1993)
Resuscitation of asphyxic newborn infants with room air or 100% oxygen
Pediatr Res, 34 (6), 809-12
PubMed 8108199

Rognum TO, Saugstad OD (1993)
Biochemical and immunological studies in SIDS victims. Clues to understanding the death mechanism
Acta Paediatr Suppl, 82 Suppl 389, 82-5
PubMed 8374202

Rootwelt T, Odden JP, Hall C, Ganes T, Saugstad OD (1993)
Cerebral blood flow and evoked potentials during reoxygenation with 21 or 100% O2 in newborn pigs
J Appl Physiol (1985), 75 (5), 2054-60
PubMed 8307859

Rootwelt T, Oyasaeter S, Saugstad OD (1993)
Transport of hypoxanthine from plasma to cerebrospinal fluid and vitreous humor in newborn pigs
J Perinat Med, 21 (3), 211-7
PubMed 8229612

Sanderud J, Bjøro K, Saugstad OD (1993)
Oxygen radicals stimulate thromboxane and prostacyclin synthesis and induce vasoconstriction in pig lungs
Scand J Clin Lab Invest, 53 (5), 447-55
PubMed 8210966

Sanderud J, Saugstad OD (1993)
Oxygen radicals induce pulmonary vasoconstriction in pigs without activating plasma proteolytic cascade systems
Eur Surg Res, 25 (3), 137-45
PubMed 8500505

Saugstad OD (1993)
[Sudden infant death--is mortality decreasing?]
Tidsskr Nor Laegeforen, 113 (12), 1446
PubMed 8332968

Saugstad OD (1993)
The future of neonatal research
Acta Paediatr, 82 (6-7), 505-9
PubMed 8338979

Saugstad OD, Danielsen K, Grønn M, Holt J, Meberg A, Silberg IE, Okland O (1993)
[Neonatal respiratory distress syndrome treated with a natural surfactant. The Norwegian Curosurf study]
Tidsskr Nor Laegeforen, 113 (19), 2389-93
PubMed 8378900

Saugstad OD, Halliday HL, Robertson B, Speer CP (1993)
Replacement therapy with porcine natural surfactant--current status and future challenges. Report from the 8th International Workshop on Surfactant Replacement, Oslo, May 20-22, 1993
Biol Neonate, 64 (5), 269-78
PubMed 7905289

Stoltenberg L, Rootwelt T, Oyasaeter S, Rognum TO, Saugstad OD (1993)
Hypoxanthine, xanthine, and uric acid concentrations in plasma, cerebrospinal fluid, vitreous humor, and urine in piglets subjected to intermittent versus continuous hypoxemia
Pediatr Res, 34 (6), 767-71
PubMed 8108190

Storm H, Rognum TO, Saugstad OD, Reichelt KL (1993)
Elevated beta-endorphin immunoreactivity in the cerebrospinal fluid in victims of sudden infant death correlates with hypoxanthine in vitreous humour
Eur J Pediatr, 152 (11), 935-8
PubMed 8276029

Publications 1992

Oroszlán G, Sanderud J, Saugstad OD, Lakatos L (1992)
[D-penicillamine: old drug, new indication? D-penicillamine reduced pulmonary hypertension induced by free radicals]
Orv Hetil, 133 (44), 2835-6, 2839
PubMed 1437106

Rootwelt T, Løberg EM, Moen A, Oyasaeter S, Saugstad OD (1992)
Hypoxemia and reoxygenation with 21% or 100% oxygen in newborn pigs: changes in blood pressure, base deficit, and hypoxanthine and brain morphology
Pediatr Res, 32 (1), 107-13
PubMed 1635835

Saugstad OD (1992)
[Use of resources and results in neonatal medicine]
Tidsskr Nor Laegeforen, 112 (6), 744
PubMed 1561592

Saugstad OD, Buø L, Johansen HT, Røise O, Aasen AO (1992)
Activation of the plasma kallikrein-kinin system in respiratory distress syndrome
Pediatr Res, 32 (4), 431-5
PubMed 1437396

Saugstad OD, Rognum TO (1992)
[Sudden infant death and sleeping position]
Tidsskr Nor Laegeforen, 112 (11), 1423-4
PubMed 1631809

Saugstad OD, Tubman TR, Gloppestad K, Halliday HL, Oyasaeter S, Curstedt T, Robertson B (1992)
Raised plasma hypoxanthine levels as a prognostic sign in preterm babies with respiratory distress syndrome treated with natural surfactant
J Perinat Med, 20 (5), 379-85
PubMed 1479521

Stoltenberg L, Saugstad OD, Rognum TO (1992)
Sudden infant death syndrome victims show local immunoglobulin M response in tracheal wall and immunoglobulin A response in duodenal mucosa
Pediatr Res, 31 (4 Pt 1), 372-5
PubMed 1570203

Publications 1991

Dueland S, Myhre K, Dueland AN, Saugstad OD (1991)
Increased plasma hypoxanthine values in humans during exposure to simulated altitude of 7,620 meters (25,000 feet)
Aviat Space Environ Med, 62 (11), 1044-9
PubMed 1741717

Oddoy A, Renner S, Saugstad OD (1991)
The influence of intratracheal saline upon the dynamic lung-thorax compliance of premature newborn rabbits
Z Erkr Atmungsorgane, 177 (3), 144-50
PubMed 1808863

Poulsen JP, Saugstad OD (1991)
Oxypurines in extracellular fluids from piglets during hypoxemia and reoxygenation
Adv Exp Med Biol, 309A, 271-4
PubMed 1789224

Rognum TO, Hauge S, Oyasaeter S, Saugstad OD (1991)
A new biochemical method for estimation of postmortem time
Forensic Sci Int, 51 (1), 139-46
PubMed 1752591

Rognum TO, Saugstad OD (1991)
Hypoxanthine levels in vitreous humor: evidence of hypoxia in most infants who died of sudden infant death syndrome
Pediatrics, 87 (3), 306-10
PubMed 1796934

Rognum TO, Saugstad OD, Lier LA (1991)
[Police investigation in crib death? How should the health services, forensic medicine and police cooperate?]
Tidsskr Nor Laegeforen, 111 (14), 1752-3
PubMed 2063388

Sanderud J, Norstein J, Saugstad OD (1991)
Reactive oxygen metabolites produce pulmonary vasoconstriction in young pigs
Pediatr Res, 29 (6), 543-7
PubMed 1866209

Saugstad OD (1991)
Moral dilemmas in neonatal medicine
Int J Technol Assess Health Care, 7 Suppl 1, 133-5
PubMed 2037427

Saugstad OD, Rognum TO (1991)
[Diagnostic criteria for sudden infant death]
Tidsskr Nor Laegeforen, 111 (23), 2829-30
PubMed 1948876

Publications 1990

Møller P, Moe N, Saugstad OD, Skullerud K, Velken M, Berg K, Nitter-Hauge S, Børresen AL (1990)
Spinal muscular atrophy type I combined with atrial septal defect in three sibs
Clin Genet, 38 (2), 81-3
PubMed 2208769

Oddoy A, Dinger J, Saugstad OD (1990)
[Hypoxic pulmonary vasoconstriction following lung damage by xanthine oxidase--studies in rats]
Z Erkr Atmungsorgane, 175 (3), 155-62
PubMed 2080631

Poulsen JP, Oyasaeter S, Sanderud J, Rognum TO, Saugstad OD (1990)
Hypoxanthine, xanthine, and uric acid concentrations in the cerebrospinal fluid, plasma, and urine of hypoxemic pigs
Pediatr Res, 28 (5), 477-81
PubMed 2255571

Poulsen JP, Rognum TO, Oyasaeter S, Saugstad OD (1990)
Changes in oxypurine concentrations in vitreous humor of pigs during hypoxemia and post-mortem
Pediatr Res, 28 (5), 482-4
PubMed 2255572

Saugstad OD (1990)
Oxygen toxicity in the neonatal period
Acta Paediatr Scand, 79 (10), 881-92
PubMed 2264459

Saugstad OD, Gloppestad K (1990)
[Surfactant treatment of premature infants with respiratory distress syndrome]
Tidsskr Nor Laegeforen, 110 (29), 3737-41
PubMed 2274941

Saugstad OD, Nygaard R (1990)
[Treatment considerations for children during terminal care]
Tidsskr Nor Laegeforen, 110 (16), 2084-7
PubMed 2368074

Saugstad OD, Rognum TO (1990)
[Sudden infant death]
Tidsskr Nor Laegeforen, 110 (29), 3717-8
PubMed 2274934

Publications 1989

Clyman RI, Saugstad OD, Mauray F (1989)
Reactive oxygen metabolites relax the lamb ductus arteriosus by stimulating prostaglandin production
Circ Res, 64 (1), 1-8
PubMed 2909293

Saugstad OD (1989)
The oxygen radical disease in neonatology
Indian J Pediatr, 56 (5), 585-93
PubMed 2632427

Saugstad OD, Sanderud J (1989)
Circulatory effects of oxygen radicals
Biomed Biochim Acta, 48 (2-3), S20-4
PubMed 2730608

Publications 1988

Rognum TO, Saugstad OD, Oyasaeter S, Olaisen B (1988)
Elevated levels of hypoxanthine in vitreous humor indicate prolonged cerebral hypoxia in victims of sudden infant death syndrome
Pediatrics, 82 (4), 615-8
PubMed 3174318

Saugstad OD (1988)
Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production
Pediatr Res, 23 (2), 143-50
PubMed 3281119

Saugstad OD (1988)
[Ethical dilemmas in modern neonatology]
Tidsskr Nor Laegeforen, 108 (12), 957-9
PubMed 3381211

Saugstad OD, Hallman M, Becher G, Oddoy A, Lium B, Lachmann B (1988)
Respiratory failure caused by intratracheal saline: additive effect of xanthine oxidase
Biol Neonate, 54 (2), 61-7
PubMed 3167134

Saugstad OD, Marklund SL (1988)
High activities of erythrocyte glutathione peroxidase in patients with the Lesch-Nyhan syndrome
Acta Med Scand, 224 (3), 281-5
PubMed 3239456

Saugstad OD, Rognum TO (1988)
High postmortem levels of hypoxanthine in the vitreous humor of premature babies with respiratory distress syndrome
Pediatrics, 81 (3), 395-8
PubMed 3422735

Publications 1987

Lachmann B, Saugstad OD, Erdmann W (1987)
Effects of surfactant replacement on respiratory failure induced by free oxygen radicals
Prog Clin Biol Res, 236B, 305-13
PubMed 3615475

Lachmann B, Saugstad OD, Klein J, Erdmann W (1987)
Acute respiratory failure induced by tracheal instillation of xanthine oxidase, its prevention and therapy by exogenous surfactant instillation
Adv Exp Med Biol, 215, 351-4
PubMed 3673737

Rooth G, Saugstad OD (1987)
Consequences of asphyxia in surfactant deficiency
J Perinat Med, 15 (5), 429-34
PubMed 3443897

Saugstad OD (1987)
[Ductus arteriosus. Physiopathological and clinical aspects]
Tidsskr Nor Laegeforen, 107 (12), 1015-8
PubMed 3299860

Saugstad OD (1987)
[HIV transmitted in the perinatal period]
Tidsskr Nor Laegeforen, 107 (6), 562-4
PubMed 3576550

Saugstad OD, Becher G, Grossmann M, Merker G, Oddoy A, Lachmann B (1987)
Acute and chronic effects of xanthine oxidase on lung thorax-compliance in guinea pigs
Intensive Care Med, 13 (1), 30-2
PubMed 3558933

Publications 1986

Lindemann R, Hågå P, Saugstad OD, Langslet A (1986)
[Congenital AV block]
Tidsskr Nor Laegeforen, 106 (2), 131-3
PubMed 3952703

Saugstad OD (1986)
[Free radicals and posthypoxic cellular damage. Importance of the hypoxanthine-xanthine oxidase system]
Tidsskr Nor Laegeforen, 106 (22), 1697-99, 1673
PubMed 3775702

Saugstad OD, Ziegler MG, Kessel B, Saunders B, Gluck L (1986)
Correlation of plasma hypoxanthine and catecholamine levels in the umbilical vein
J Perinat Med, 14 (5), 339-43
PubMed 3783399

Publications 1985

Hallman M, Saugstad OD, Porreco RP, Epstein BL, Gluck L (1985)
Role of myoinositol in regulation of surfactant phospholipids in the newborn
Early Hum Dev, 10 (3-4), 245-54
PubMed 3838720

Lindemann R, Hågå P, Saugstad OD, Langslet A (1985)
Congenital complete AV-block
J Oslo City Hosp, 35 (9-10), 103-6
PubMed 4067711

Saugstad OD (1985)
Oxygen radicals and pulmonary damage
Pediatr Pulmonol, 1 (3), 167-75
PubMed 3903637

Publications 1984

Saugstad OD (1984)
Pathogenetic aspects of respiratory distress syndrome in adults and newborns. Experimental and clinical data
Eur Surg Res, 16 Suppl 2, 113-9
PubMed 6562962

Saugstad OD, Hallman M, Abraham JL, Epstein B, Cochrane C, Gluck L (1984)
Hypoxanthine and oxygen induced lung injury: a possible basic mechanism of tissue damage?
Pediatr Res, 18 (6), 501-4
PubMed 6610852

Publications 1983

Bejar R, Saugstad OD, James H, Gluck L (1983)
Increased hypoxanthine concentrations in cerebrospinal fluid of infants with hydrocephalus
J Pediatr, 103 (1), 44-8
PubMed 6864395

Publications 1982

Lium B, Saugstad OD, Aasen AO, Guldvog I, Nordstoga K, Amundsen E (1982)
Experimental post-traumatic lung insufficiency in dogs. Gross and light microscopic lung lesions
Acta Vet Scand, 23 (1), 118-27
PubMed 7113861

Lium B, Aasen AO, Saugstad OD, Guldvog I, Nordstoga K, Amundsen E (1982)
Experimental post-traumatic lung insufficiency in dogs: ultrastructure of lung lesions
Acta Pathol Microbiol Immunol Scand A, 90 (2), 113-23
PubMed 7080819

Saugstad OD (1982)
[Lung insufficiency in neonatal period]
Tidsskr Nor Laegeforen, 102 (9-10), 546-51
PubMed 6897590

Saugstad OD, Gluck L (1982)
Plasma hypoxanthine levels in newborn infants: a specific indicator of hypoxia
J Perinat Med, 10 (6), 266-72
PubMed 6891718

Saugstad OD, Harvie A, Langslet A (1982)
Activation of the kallikrein-kinin system in premature infants with respiratory distress syndrome (RDS)
Acta Paediatr Scand, 71 (6), 965-8
PubMed 6925441

Saugstad OD, Wung WE, Howell SB, Gluck L (1982)
Determination of plasma hypoxanthine: a comparison of high-pressure liquid chromatographic and oxygen consumption methods
Anal Biochem, 122 (1), 159-63
PubMed 7103081

Saugstad OD, Aasen AO, Guldvog I, Lium B, Lyngaas K, Amundsen E (1982)
Changes of components of the plasma kallikrein-kinin system during experimental lung insufficiency in dogs
Acta Chir Scand Suppl, 509, 61-7
PubMed 6962621

Sørlie D, Myhre K, Saugstad OD, Giercksky KE (1982)
Release of hypoxanthine and phosphate from exercising human legs with and without arterial insufficiency
Acta Med Scand, 211 (4), 281-6
PubMed 7102367

Publications 1981

Flatmark A, Rugstad HE, Saugstad OD (1981)
[The use of drugs in Norwegian prisons]
Tidsskr Nor Laegeforen, 101 (19-21), 1145-50
PubMed 7281140

Saugstad OD (1981)
Letter to the editor: comparison of hypoxanthine and lactate as indicators of hypoxia
Pediatr Res, 15 (8), 1140
PubMed 7267189

Publications 1980

Guldvog I, Saugstad OD, Aasen AO, Dale J, Lium B, Larsbraaten M, Lyngaas K, Amundsen E (1980)
Blood cells and coagulation during experimental lung insufficiency in dogs
Acta Chir Scand Suppl, 499, 131-9
PubMed 6935893

Saugstad OD (1980)
[Health status of Norwegian longterm prisoners]
Tidsskr Nor Laegeforen, 100 (8-9), 509-14
PubMed 7385214

Saugstad OD, Aasen AO (1980)
Plasma hypoxanthine concentrations in pigs. A prognostic aid in hypoxia
Eur Surg Res, 12 (2), 123-9
PubMed 7408920

Saugstad OD, Aasen AO, Guldvog I, Lium B, Larsbraaten M, Lyngaas K, Amundsen E (1980)
Activation of the kallikrein-kinin system during experimental lung insufficiency in dogs
Acta Chir Scand Suppl, 499, 123-9
PubMed 6935892

Thiringer K, Saugstad OD, Kjellmer I (1980)
Plasma hypoxanthine in exteriorized, acutely asphyxiated fetal lambs
Pediatr Res, 14 (8), 905-10
PubMed 6775273

Aasen AO, Saugstad OD, Lium B, Guldvog I, Lyngaas K, Larsbraaten M, Amundsen E (1980)
Plasma antiplasmin activities in experimental lung insufficiency
Acta Chir Scand Suppl, 499, 113-21
PubMed 6935891

Publications 1979

Saugstad OD (1979)
[New aspects of hypoxia]
Tidsskr Nor Laegeforen, 99 (7), 360-3
PubMed 432858

Saugstad OD (1979)
[Posttraumatic respiratory failure (shock lung)]
Tidsskr Nor Laegeforen, 99 (1), 7-11
PubMed 760245

Aasen AO, Saugstad OD (1979)
Hypoxanthine in lethal canine endotoxin shock
Circ Shock, 6 (3), 277-83
PubMed 498432

Publications 1978

Meberg A, Saugstad OD (1978)
Hypoxanthine in cerebrospinal fluid in children
Scand J Clin Lab Invest, 38 (5), 437-40
PubMed 705228

Saugstad OD, Olaisen B (1978)
Post-mortem hypoxanthine levels in the vitreous humour. An introductory report
Forensic Sci, 12 (1), 33-6
PubMed 711084

Saugstad OD, Schrader H (1978)
The determination of inosine and hypoxanthine in the rat brain during normothermic and hypothermic anoxia
Acta Neurol Scand, 57 (4), 281-8
PubMed 665150

Saugstad OD, Aasen AO, Hetland O (1978)
Plasma hypoxanthine levels in pigs during acute hypoxemia. A correlation between lactate and base deficit concentrations
Eur Surg Res, 10 (5), 314-21
PubMed 30633

Aasen AO, Frolich W, Saugstad OD, Amundsen E (1978)
Plasma kallikrein activity and prekallikrein levels during endotoxin shock in dogs
Eur Surg Res, 10 (1), 50-62
PubMed 344043

Publications 1977

Saugstad OD (1977)
Hypoxanthine as an indicator of tissue hypoxia. A study of plasma, cerebro-spinal and brain tissue concentrations
J Oslo City Hosp, 27 (3), 29-40
PubMed 845718

Saugstad OD, Bo G, Ostrem T, Aasen AO (1977)
Hypoxanthine levels of plasma during hypoxemia in dogs
Eur Surg Res, 9 (1), 23-33
PubMed 14834

Saugstad OD, Kroese A, Myhre HO, Andersen R (1977)
Alteration of plasma hypoxanthine concentration during ischaemia in the forelimb of the pig
Scand J Clin Lab Invest, 37 (6), 517-20
PubMed 10733408

Saugstad OD, Ostrem T (1977)
Hypoxanthine and urate levels of plasma during and after hemorrhagic hypotension in dogs
Eur Surg Res, 9 (1), 48-56
PubMed 844465

Publications 1976

Saugstad OD, Schrader H, Aasen AO (1976)
Alteration of the hypoxanthine level in cerebrospinal fluid as an indicator of tissue hypoxia
Brain Res, 112 (1), 188-9
PubMed 947488

Publications 1975

Saugstad OD (1975)
Hypoxanthine as a measurement of hypoxia
Pediatr Res, 9 (4), 158-61
PubMed 1143950

Saugstad OD (1975)
Letter: Hyperuricaemia and epileptic seizures: a possible explanation
Lancet, 2 (7936), 665
PubMed 52039

Saugstad OD (1975)
The determination of hypoxanthine and xanthine with a PO2 electrode
Pediatr Res, 9 (7), 575-9
PubMed 1161346