Bernt Christian Hellerud
Position: Post doc, PhD
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Visit the Mollnes group home page at UiO for more information

 

Author network for Bernt Christian Hellerud by COREMINE medical


Publications 2017

Harboe M, Johnson C, Nymo S, Ekholt K, Schjalm C, Lindstad JK, Pharo A, Hellerud BC, Nilsson Ekdahl K, Mollnes TE, Nilsson PH (2017)
Properdin binding to complement activating surfaces depends on initial C3b deposition
Proc Natl Acad Sci U S A, 114 (4), E534-E539
PubMed 28069958

Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzæg P, Nielsen EW, Mollnes TE (2017)
Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis
J Intensive Care, 5, 21
PubMed 28261486

Publications 2015

Hellerud BC, Olstad OK, Nielsen EW, Trøseid AM, Skadberg Ø, Thorgersen EB, Vege Å, Mollnes TE, Brandtzæg P (2015)
Massive Organ Inflammation in Experimental and in Clinical Meningococcal Septic Shock
Shock, 44 (5), 458-69
PubMed 26473439

Publications 2014

Owen EP, Würzner R, Leisegang F, Rizkallah P, Whitelaw A, Simpson J, Thomas AD, Harris CL, Giles JL, Hellerud BC, Mollnes TE, Morgan BP, Potter PC, Orren A (2014)
A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases
Mol Immunol, 64 (1), 170-6
PubMed 25534848

Publications 2013

Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn M, Scott H, Mollnes TE (2013)
Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis
J Immunol, 191 (2), 819-27
PubMed 23761634

Thorgersen EB, Pischke SE, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Hellerud BC, Mollnes TE (2013)
Systemic CD14 inhibition attenuates organ inflammation in porcine Escherichia coli sepsis
Infect Immun, 81 (9), 3173-81
PubMed 23774598

Publications 2012

Barratt-Due A, Sokolov A, Gustavsen A, Hellerud BC, Egge K, Pischke SE, Lindstad JK, Pharo A, Castellheim A, Thorgersen EB, Mollnes TE (2012)
Polyvalent immunoglobulin significantly attenuated the formation of IL-1β in Escherichia coli-induced sepsis in pigs
Immunobiology, 218 (5), 683-9
PubMed 22947599

Sokolov A, Hellerud BC, Johannessen EA, Mollnes TE (2012)
Inflammatory response induced by candidate biomaterials of an implantable microfabricated sensor
J Biomed Mater Res A, 100 (5), 1142-50
PubMed 22337626

Sokolov A, Hellerud BC, Tønnessen TI, Johannessen EA, Mollnes TE (2012)
Activation of coagulation and platelets by candidate membranes of implantable devices in a whole blood model without soluble anticoagulant
J Biomed Mater Res A, 101 (2), 575-81
PubMed 22949225

Publications 2011

Barratt-Due A, Johansen HT, Sokolov A, Thorgersen EB, Hellerud BC, Reubsaet JL, Seip KF, Tønnessen TI, Lindstad JK, Pharo A, Castellheim A, Mollnes TE, Nielsen EW (2011)
The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis
Shock, 36 (5), 517-23
PubMed 21921836

Brekke OL, Hellerud BC, Christiansen D, Fure H, Castellheim A, Nielsen EW, Pharo A, Lindstad JK, Bergseth G, Leslie G, Lambris JD, Brandtzaeg P, Mollnes TE (2011)
Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood
Mol Immunol, 48 (15-16), 2159-69
PubMed 21839519

Sokolov A, Hellerud BC, Lambris JD, Johannessen EA, Mollnes TE (2011)
Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor
J Diabetes Sci Technol, 5 (6), 1490-8
PubMed 22226271

Sokolov A, Hellerud BC, Pharo A, Johannessen EA, Mollnes TE (2011)
Complement activation by candidate biomaterials of an implantable microfabricated medical device
J Biomed Mater Res B Appl Biomater, 98 (2), 323-9
PubMed 21648060

Publications 2010

Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tønnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P (2010)
Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis
Crit Care Med, 38 (6), 1467-74
PubMed 20400898

Publications 2009

Hellerud BC, Aase A, Herstad TK, Naess LM, Kristiansen LH, Trøseid AM, Harboe M, Lappegård KT, Brandtzaeg P, Høiby EA, Mollnes TE (2009)
Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies
Infect Immun, 78 (2), 802-9
PubMed 19933829

Lappegård KT, Christiansen D, Pharo A, Thorgersen EB, Hellerud BC, Lindstad J, Nielsen EW, Bergseth G, Fadnes D, Abrahamsen TG, Høiby EA, Schejbel L, Garred P, Lambris JD, Harboe M, Mollnes TE (2009)
Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature
Proc Natl Acad Sci U S A, 106 (37), 15861-6
PubMed 19717455

Nielsen EW, Hellerud BC, Thorgersen EB, Castellheim A, Pharo A, Lindstad J, Tønnessen TI, Brandtzaeg P, Mollnes TE (2009)
A new dynamic porcine model of meningococcal shock
Shock, 32 (3), 302-9
PubMed 19174740

Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE (2009)
CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs
FASEB J, 24 (3), 712-22
PubMed 19841036

Publications 2008

Castellheim A, Thorgersen EB, Hellerud BC, Pharo A, Johansen HT, Brosstad F, Gaustad P, Brun H, Fosse E, Tønnessen TI, Nielsen EW, Mollnes TE (2008)
New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs
Scand J Immunol, 68 (1), 75-84
PubMed 18466195

Hellerud BC, Stenvik J, Espevik T, Lambris JD, Mollnes TE, Brandtzaeg P (2008)
Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation
Infect Immun, 76 (9), 4183-9
PubMed 18591229

Publications 2005

Hellerud BC, Kittang OB, Vesterhus P (2005)
[A three-year-old boy with hypoglycaemia]
Tidsskr Nor Laegeforen, 125 (15), 2031-2
PubMed 16114124

Publications 2002

Hellerud BC, Storm H (2002)
Skin conductance and behaviour during sensory stimulation of preterm and term infants
Early Hum Dev, 70 (1-2), 35-46
PubMed 12441203