Publications

Publications published since 2003 or in press from OUS - Cell signalling research group

43 publications found

Publications in press

1. Lehtiö L, Chi NW, Krauss S
   Tankyrases as Drug Targets
   FEBS J (in press)
   PubMed 23648170

Publications 2013

1. Klimova L, Lachova J, Machon O, Sedlacek R, Kozmik Z (2013)
   Generation of mRx-Cre Transgenic Mouse Line for Efficient Conditional Gene Deletion in Early Retinal Progenitors
   PLoS One, 8 (5), e63029
   PubMed 23667567
2. Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M (2013)
   A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation-Driven Colorectal Tumor Growth
   Cancer Res, 73 (10), 3132-3144
   PubMed 23539443
3. Solberg N, Krauss S (2013)
   Luciferase assay to study the activity of a cloned promoter DNA fragment
   Methods Mol Biol, 977, 65-78
   PubMed 23436354
4. Voronkov A, Holsworth DD, Waaler J, Wilson SR, Ekblad B, Perdreau-Dahl H, Dinh H, Drewes G, Hopf C, Morth JP, Krauss S (2013)
   Structural Basis and SAR for G007-LK, a Lead Stage 1,2,4-Triazole Based Specific Tankyrase 1/2 Inhibitor
   J Med Chem, 56 (7), 3012-23
   PubMed 23473363
5. Voronkov A, Krauss S (2013)
   Wnt/beta-catenin signaling and small molecule inhibitors
   Curr Pharm Des, 19 (4), 634-64
   PubMed 23016862

Publications 2012

1. Holsworth DD, Krauss S (2012)
   Recent Advances in Wnt/beta-Catenin Pathway Small-Molecule Inhibitors
   Annu. Rep. Med. Chem., 47, 393-409
2. Roberg-Larsen H, Strand MF, Grimsmo A, Olsen PA, Dembinski JL, Rise F, Lundanes E, Greibrokk T, Krauss S, Wilson SR (2012)
   High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry
   J Chromatogr A, 1255, 291-7
   PubMed 22410154
3. Solberg N, Machon O, Krauss S (2012)
   Characterization and functional analysis of the 5'-flanking promoter region of the mouse Tcf3 gene
   Mol Cell Biochem, 360 (1-2), 289-99
   PubMed 21935611
4. Solberg N, Machon O, Machonova O, Krauss S (2012)
   Mouse Tcf3 represses canonical Wnt signaling by either competing for ?-catenin binding or through occupation of DNA-binding sites
   Mol Cell Biochem, 365 (1-2), 53-63
   PubMed 22270545
5. Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
   A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
   Cancer Res, 72 (11), 2822-32
   PubMed 22440753

Publications 2011

1. Irvine EE, Drinkwater L, Radwanska K, Al-Qassab H, Smith MA, O'Brien M, Kielar C, Choudhury AI, Krauss S, Cooper JD, Withers DJ, Giese KP (2011)
   Insulin receptor substrate 2 is a negative regulator of memory formation
   Learn Mem, 18 (6), 375-83
   PubMed 21597043
2. Jing Y, Machon O, Hampl A, Dvorak P, Xing Y, Krauss S (2011)
   In vitro differentiation of mouse embryonic stem cells into neurons of the dorsal forebrain
   Cell Mol Neurobiol, 31 (5), 715-27
   PubMed 21424551
3. Strand MF, Wilson SR, Dembinski JL, Holsworth DD, Khvat A, Okun I, Petersen D, Krauss S (2011)
   A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model
   PLoS One, 6 (6), e19904
   PubMed 21698280
4. Waaler J, Machon O, von Kries JP, Wilson SR, Lundenes E, Wedlich D, Gradl D, Paulsen JE, Machonova O, Dembinski JL, Dinh H, Krauss S (2011)
   Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth
   Cancer Res, 71 (1), 197-205
   PubMed 21199802

Publications 2010

1. Dembinski JL, Krauss S (2010)
   A Distinct Slow-Cycling Cancer Stem-like Subpopulation of Pancreatic Adenocarcinoma Cells is maintained in Vivo
   Cancers, 2 (4), 2011-2025
   PublikaID 116
2. Kalousova A, Mavropoulos A, Adams BA, Nekrep N, Li Z, Krauss S, Stainier DY, German MS (2010)
   Dachshund homologues play a conserved role in islet cell development
   Dev Biol, 348 (2), 143-52
   PubMed 20869363
3. Olsen PA, Gelazauskaite M, Randøl M, Krauss S (2010)
   Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction
   BMC Mol Biol, 11, 35
   PubMed 20459736
4. Wilson SR, Strand MF, Krapp A, Rise F, Herstad G, Malterud KE, Krauss S (2010)
   Hedgehog antagonists cyclopamine and dihydroveratramine can be mistaken for each other in Veratrum album
   J Pharm Biomed Anal, 53 (3), 497-502
   PubMed 20646889
5. Wilson SR, Strand MF, Krapp A, Rise F, Petersen D, Krauss S (2010)
   Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified
   J Pharm Biomed Anal, 52 (5), 707-13
   PubMed 20236786

Publications 2009

1. Dembinski JL, Krauss S (2009)
   Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma
   Clin Exp Metastasis, 26 (7), 611-23
   PubMed 19421880
2. Hildrestrand GA, Neurauter CG, Diep DB, Castellanos CG, Krauss S, Bjørås M, Luna L (2009)
   Expression patterns of Neil3 during embryonic brain development and neoplasia
   BMC Neurosci, 10, 45
   PubMed 19426544
3. Kunke D, Bryja V, Mygland L, Arenas E, Krauss S (2009)
   Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs
   Biochem Biophys Res Commun, 386 (4), 628-33
   PubMed 19545542
4. Olsen PA, Solhaug A, Booth JA, Gelazauskaite M, Krauss S (2009)
   Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases
   DNA Repair (Amst), 8 (3), 298-308
   PubMed 19071233

Publications 2008

1. Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Studer M, Rubenstein JL (2008)
   COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling
   Cereb Cortex, 18 (9), 2117-31
   PubMed 18165280
2. Solberg N, Machon O, Krauss S (2008)
   Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool
   Dev Dyn, 237 (7), 1799-811
   PubMed 18521945

Publications 2007

1. Fujimura N, Vacik T, Machon O, Vlcek C, Scalabrin S, Speth M, Diep D, Krauss S, Kozmik Z (2007)
   Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5
   J Biol Chem, 282 (2), 1225-37
   PubMed 17090534
2. Hildrestrand GA, Diep DB, Kunke D, Bolstad N, Bjørås M, Krauss S, Luna L (2007)
   The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation
   DNA Repair (Amst), 6 (6), 723-32
   PubMed 17236821
3. Kadowaki M, Nakamura S, Machon O, Krauss S, Radice GL, Takeichi M (2007)
   N-cadherin mediates cortical organization in the mouse brain
   Dev Biol, 304 (1), 22-33
   PubMed 17222817
4. Kreslova J, Machon O, Ruzickova J, Lachova J, Wawrousek EF, Kemler R, Krauss S, Piatigorsky J, Kozmik Z (2007)
   Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function
   Genesis, 45 (4), 157-68
   PubMed 17410548
5. Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, Krauss S (2007)
   A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus
   Dev Biol, 311 (1), 223-37
   PubMed 17916349
6. Persson AS, Westman E, Wang FH, Khan FH, Spenger C, Lavebratt C (2007)
   Kv1.1 null mice have enlarged hippocampus and ventral cortex
   BMC Neurosci, 8, 10
   PubMed 17250763

Publications 2005

1. Backman M, Machon O, Mygland L, van den Bout CJ, Zhong W, Taketo MM, Krauss S (2005)
   Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon
   Dev Biol, 279 (1), 155-68
   PubMed 15708565
2. Lorico A, Bratbak D, Meyer J, Kunke D, Krauss S, Plott WE, Solodushko V, Baum C, Fodstad O, Rappa G (2005)
   Gamma-glutamylcysteine synthetase and L-buthionine-(S,R)-sulfoximine: a new selection strategy for gene-transduced neural and hematopoietic stem/progenitor cells
   Hum Gene Ther, 16 (6), 711-24
   PubMed 15960602
3. Machon O, Backman M, Krauss S, Kozmik Z (2005)
   The cellular fate of cortical progenitors is not maintained in neurosphere cultures
   Mol Cell Neurosci, 30 (3), 388-97
   PubMed 16150605
4. Olsen PA, Randol M, Krauss S (2005)
   Implications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotides
   Gene Ther, 12 (6), 546-51
   PubMed 15674399
5. Olsen PA, Randøl M, Luna L, Brown T, Krauss S (2005)
   Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends
   J Gene Med, 7 (12), 1534-44
   PubMed 16025558

Publications 2004

1. Diep DB, Hoen N, Backman M, Machon O, Krauss S (2004)
   Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain
   Brain Res Dev Brain Res, 153 (2), 261-70
   PubMed 15527894
2. Petersen PH, Zou K, Krauss S, Zhong W (2004)
   Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
   Nat Neurosci, 7 (8), 803-11
   PubMed 15273690
3. Rappa G, Kunke D, Holter J, Diep DB, Meyer J, Baum C, Fodstad O, Krauss S, Lorico A (2004)
   Efficient expansion and gene transduction of mouse neural stem/progenitor cells on recombinant fibronectin
   Neuroscience, 124 (4), 823-30
   PubMed 15026123

Publications 2003

1. Backman M, Machon O, Van Den Bout CJ, Krauss S (2003)
   Targeted disruption of mouse Dach1 results in postnatal lethality
   Dev Dyn, 226 (1), 139-44
   PubMed 12508235
2. Machon O, van den Bout CJ, Backman M, Kemler R, Krauss S (2003)
   Role of beta-catenin in the developing cortical and hippocampal neuroepithelium
   Neuroscience, 122 (1), 129-43
   PubMed 14596855
3. Olsen PA, McKeen C, Krauss S (2003)
   Branched oligonucleotides induce in vivo gene conversion of a mutated EGFP reporter
   Gene Ther, 10 (21), 1830-40
   PubMed 12960973