Jo Waaler
Position: PhD Student
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Visit the homepage of the Krauss group at the CMBN for more information.
 

Author network for Jo Waaler by COREMINE medical


Publications 2017

Vehus T, Waaler J, Krauss S, Lundanes E, Wilson SR (2017)
Combining HIC, SEC, and IEX with Fluorescence Polarization for Drug Target Discovery
LC GC Eur., 30 (5), 232-239

Publications 2016

Vehus T, Roberg-Larsen H, Waaler J, Aslaksen S, Krauss S, Wilson SR, Lundanes E (2016)
Versatile, sensitive liquid chromatography mass spectrometry - Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins
Sci Rep, 6, 37507
PubMed 27897190

Publications 2015

Haikarainen T, Waaler J, Ignatev A, Nkizinkiko Y, Venkannagari H, Obaji E, Krauss S, Lehtiö L (2015)
Development and structural analysis of adenosine site binding tankyrase inhibitors
Bioorg Med Chem Lett, 26 (2), 328-33
PubMed 26706174

Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestøl K, Waaler J, Krauss S, Stenmark H (2015)
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol Cancer Res, 13 (11), 1487-501
PubMed 26124443

Zhong L, Ding Y, Bandyopadhyay G, Waaler J, Börgeson E, Smith S, Zhang M, Phillips SA, Mahooti S, Mahata SK, Shao J, Krauss S, Chi NW (2015)
The PARsylation activity of tankyrase in adipose tissue modulates systemic glucose metabolism in mice
Diabetologia, 59 (3), 582-91
PubMed 26631215

Publications 2013

Lau T, Chan E, Callow M, Waaler J, Boggs J, Blake RA, Magnuson S, Sambrone A, Schutten M, Firestein R, Machon O, Korinek V, Choo E, Diaz D, Merchant M, Polakis P, Holsworth DD, Krauss S, Costa M (2013)
A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth
Cancer Res, 73 (10), 3132-44
PubMed 23539443

Stratford EW, Daffinrud J, Munthe E, Castro R, Waaler J, Krauss S, Myklebost O (2013)
The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines
Cancer Med, 3 (1), 36-46
PubMed 24403055

Voronkov A, Holsworth DD, Waaler J, Wilson SR, Ekblad B, Perdreau-Dahl H, Dinh H, Drewes G, Hopf C, Morth JP, Krauss S (2013)
Structural basis and SAR for G007-LK, a lead stage 1,2,4-triazole based specific tankyrase 1/2 inhibitor
J Med Chem, 56 (7), 3012-23
PubMed 23473363

Publications 2012

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
Cancer Res, 72 (11), 2822-32
PubMed 22440753

Publications 2011

Waaler J, Machon O, von Kries JP, Wilson SR, Lundenes E, Wedlich D, Gradl D, Paulsen JE, Machonova O, Dembinski JL, Dinh H, Krauss S (2011)
Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth
Cancer Res, 71 (1), 197-205
PubMed 21199802