Caroline E. Nunes-Xavier
Position: PostDoc, PhD
Phone: +47 22 78 18 75

Area of research
B7-H3/CD276 is a glycosylated type 1 transmembrane protein that is overexpressed in various types of cancer, facilitating tumor metastasis formation and resistance to therapy. We are interested in the molecular basis of the B7-H3 biological properties and its relation to tumorigenesis.

Academic qualifications
PhD in Molecular Biology of Cancer, Marie Curie predoctoral fellow, University of Valencia, Spain. 2011
Master in Molecular Biology, Cellular Biology and Genetics, University of Valencia, Spain. 2008
Master in Molecular Biology, Biochemistry and Physiology, University of Oslo, Norway. 2007
Bachelor in Natural Sciences, University of Oslo, Norway. 2005


Author network for Caroline Elisabeth Nunes-Xavier by COREMINE medical

Publications 2016

Alonso A, Nunes-Xavier CE, Bayn Y, Pulido R (2016)
The Extended Family of Protein Tyrosine Phosphatases
Methods Mol Biol, 1447, 1-23
PubMed 27514797

Errarte P, Guarch R, Pulido R, Blanco L, Nunes-Xavier CE, Beitia M, Gil J, Angulo JC, Lpez JI, Larrinaga G (2016)
The Expression of Fibroblast Activation Protein in Clear Cell Renal Cell Carcinomas Is Associated with Synchronous Lymph Node Metastases
PLoS One, 11 (12), e0169105
PubMed 28033421

Nunes-Xavier CE, Karlsen KF, Tekle C, Pedersen C, yjord T, Hongisto V, Nesland JM, Tan M, Sahlberg KK, Fodstad (2016)
Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors
Oncotarget, 7 (6), 6891-901
PubMed 26771843

Nunes-Xavier CE, Pulido R (2016)
Global RT-PCR and RT-qPCR Analysis of the mRNA Expression of the Human PTPome
Methods Mol Biol, 1447, 25-37
PubMed 27514798

Publications 2014

Nygren MK, Tekle C, Ingebrigtsen VA, Mkel R, Krohn M, Aure MR, Nunes-Xavier CE, Perl M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Brresen-Dale AL, Fodstad , Sahlberg KK, Leivonen SK (2014)
Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
Br J Cancer, 110 (8), 2072-80
PubMed 24577056