John Kjekshus
Position: Professor Emeritus, MD PhD
Phone:
Email:

Stipendiates: Elena Soroka, Torgeir Wethal

Main focus:
Coronary disease. Heart failure. Clinical trialss.

Main methods:
Hemodynamic studies. Laboratory testing.

Project:
Low-frequency helicopter noise as a cardiovascular risk factor

Aim:
Prospective investigation of noise and effects provoked by noise on endothelial function and signal markers for endothelial function and inflammation

 

Author network for John Kjekshus by COREMINE medical


Publications 2017

Ellingsen Ø, Halle M, Conraads V, Støylen A, Dalen H, Delagardelle C, Larsen AI, Hole T, Mezzani A, Van Craenenbroeck EM, Videm V, Beckers P, Christle JW, Winzer E, Mangner N, Woitek F, Höllriegel R, Pressler A, Monk-Hansen T, Snoer M, Feiereisen P, Valborgland T, Kjekshus J, Hambrecht R, Gielen S et al. (2017)
High-Intensity Interval Training in Patients With Heart Failure With Reduced Ejection Fraction
Circulation, 135 (9), 839-849
PubMed 28082387

Publications 2016

Arain F, Gullestad L, Nymo S, Kjekshus J, Cleland JG, Michelsen A, McMurray JJ, Wikstrand J, Aukrust P, Ueland T (2016)
Low YKL-40 in chronic heart failure may predict beneficial effects of statins: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA)
Biomarkers, 1-7 (in press)
PubMed 27325138

Publications 2015

Abdul-Rahim AH, Perez AC, Fulton RL, Jhund PS, Latini R, Tognoni G, Wikstrand J, Kjekshus J, Lip GY, Maggioni AP, Tavazzi L, Lees KR, McMurray JJ (2015)
Response to Letter Regarding Article, "Risk of Stroke in Chronic Heart Failure Patients Without Atrial Fibrillation: Analysis of the Controlled Rosuvastatin in Multinational Trial Heart Failure (CORONA) and the Gruppo Italiano per lo Studio della Sopravvivenza nell'Insufficienza Cardiaca-Heart Failure (GISSI-HF) Trials."
Circulation, 132 (22), e358
PubMed 26621661

Abdul-Rahim AH, Perez AC, Fulton RL, Jhund PS, Latini R, Tognoni G, Wikstrand J, Kjekshus J, Lip GY, Maggioni AP, Tavazzi L, Lees KR, McMurray JJ, Investigators of the Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA), GISSI-Heart Failure (GISSI-HF) Committees and Investigators (2015)
Risk of Stroke in Chronic Heart Failure Patients Without Atrial Fibrillation: Analysis of the Controlled Rosuvastatin in Multinational Trial Heart Failure (CORONA) and the Gruppo Italiano per lo Studio della Sopravvivenza nell'Insufficienza Cardiaca-Heart Failure (GISSI-HF) Trials
Circulation, 131 (17), 1486-94; discussion 1494
PubMed 25810334

Askevold ET, Gullestad L, Nymo S, Kjekshus J, Yndestad A, Latini R, Cleland JG, McMurray JJ, Aukrust P, Ueland T (2015)
Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
PLoS One, 10 (8), e0133970
PubMed 26288364

Damman K, Kjekshus J, Wikstrand J, Cleland JG, Komajda M, Wedel H, Waagstein F, McMurray JJ (2015)
Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction
Eur J Heart Fail, 18 (3), 328-36
PubMed 26693947

Feinstein MJ, Jhund P, Kang J, Ning H, Maggioni A, Wikstrand J, Kjekshus J, Tavazzi L, McMurray J, Lloyd-Jones DM (2015)
Do statins reduce the risk of myocardial infarction in patients with heart failure? A pooled individual-level reanalysis of CORONA and GISSI-HF
Eur J Heart Fail, 17 (4), 434-41
PubMed 25684642

Haver VG, Mateo Leach I, Kjekshus J, Fox JC, Wedel H, Wikstrand J, de Boer RA, van Gilst WH, McMurray JJ, van Veldhuisen DJ, van der Harst P (2015)
Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA)
Eur J Heart Fail, 17 (3), 313-9
PubMed 25639660

Kjekshus J (2015)
Are statins failing in heart failure?
Eur Heart J, 36 (24), 1502-4
PubMed 25883176

Kjekshus J (2015)
Inflammation: Friend and Foe
EBioMedicine, 2 (7), 634-5
PubMed 26288833

Smedsrud MK, Gravning J, Omland T, Eek C, Mørkrid L, Skulstad H, Aaberge L, Bendz B, Kjekshus J, Edvardsen T (2015)
Sensitive cardiac troponins and N-terminal pro-B-type natriuretic peptide in stable coronary artery disease: correlation with left ventricular function as assessed by myocardial strain
Int J Cardiovasc Imaging, 31 (5), 967-73
PubMed 25788439

Wethal T, Røysland R, Torbjørn O, Kjekshus J (2015)
Exercise-induced vasodilation in healthy males: A marker of reduced endothelial function
Scand Cardiovasc J, 49 (3), 123-9
PubMed 25752356

Publications 2014

Badar AA, Perez-Moreno AC, Jhund PS, Wong CM, Hawkins NM, Cleland JG, van Veldhuisen DJ, Wikstrand J, Kjekshus J, Wedel H, Watkins S, Gardner RS, Petrie MC, McMurray JJ (2014)
Relationship between angina pectoris and outcomes in patients with heart failure and reduced ejection fraction: an analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
Eur Heart J, 35 (48), 3426-33
PubMed 25265976

Haver VG, Verweij N, Kjekshus J, Fox JC, Wedel H, Wikstrand J, van Gilst WH, de Boer RA, van Veldhuisen DJ, van der Harst P (2014)
The impact of coronary artery disease risk loci on ischemic heart failure severity and prognosis: association analysis in the COntrolled ROsuvastatin multiNAtional trial in heart failure (CORONA)
BMC Med Genet, 15, 140
PubMed 25528061

Kristensen SL, Jhund PS, Køber L, Preiss D, Kjekshus J, McKelvie RS, Zile MR, Anand IS, Wikstrand J, Wedel H, Komajda M, Carson PE, Cleland JG, McMurray JJ (2014)
Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction
Eur J Heart Fail, 17 (2), 169-76
PubMed 25756844

Kristensen SL, Køber L, Jhund PS, Solomon SD, Kjekshus J, McKelvie RS, Zile MR, Granger CB, Wikstrand J, Komajda M, Carson PE, Pfeffer MA, Swedberg K, Wedel H, Yusuf S, McMurray JJ (2014)
International geographic variation in event rates in trials of heart failure with preserved and reduced ejection fraction
Circulation, 131 (1), 43-53
PubMed 25406306

Perez-Moreno AC, Jhund PS, Macdonald MR, Petrie MC, Cleland JG, Böhm M, van Veldhuisen DJ, Gullestad L, Wikstrand J, Kjekshus J, Lewsey JD, McMurray JJ (2014)
Fatigue as a predictor of outcome in patients with heart failure: analysis of CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure)
JACC Heart Fail, 2 (2), 187-97
PubMed 24720928

Perez AC, Jhund PS, Stott DJ, Gullestad L, Cleland JG, van Veldhuisen DJ, Wikstrand J, Kjekshus J, McMurray JJ (2014)
Thyroid-stimulating hormone and clinical outcomes: the CORONA trial (controlled rosuvastatin multinational study in heart failure)
JACC Heart Fail, 2 (1), 35-40
PubMed 24622117

Rogers JK, Jhund PS, Perez AC, Böhm M, Cleland JG, Gullestad L, Kjekshus J, van Veldhuisen DJ, Wikstrand J, Wedel H, McMurray JJ, Pocock SJ (2014)
Effect of rosuvastatin on repeat heart failure hospitalizations: the CORONA Trial (Controlled Rosuvastatin Multinational Trial in Heart Failure)
JACC Heart Fail, 2 (3), 289-97
PubMed 24952697

Swerdlow DI, Preiss D, Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T, Sofat R, Stender S, Johnson PC, Scott RA, Leusink M, Verweij N, Sharp SJ, Guo Y, Giambartolomei C, Chung C, Peasey A, Amuzu A, Li K, Palmen J, Howard P, Cooper JA, Drenos F, Li YR, Lowe G et al. (2014)
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
Lancet, 385 (9965), 351-61
PubMed 25262344

Ueland T, Aukrust P, Nymo SH, Kjekshus J, McMurray JJ, Wikstrand J, Block D, Zaugg C, Gullestad L (2014)
Novel extracellular matrix biomarkers as predictors of adverse outcome in chronic heart failure: association between biglycan and response to statin therapy in the CORONA trial
J Card Fail, 21 (2), 153-9
PubMed 25451704

Ueland T, Aukrust P, Nymo SH, Kjekshus J, McMurray JJ, Wikstrand J, Wienhues-Thelen UH, Block D, Zaugg C, Gullestad L (2014)
Predictive value of endostatin in chronic heart failure patients with poor kidney function
Cardiology, 130 (1), 17-22
PubMed 25428583

Publications 2013

Batty JA, Hall AS, White HL, Wikstrand J, de Boer RA, van Veldhuisen DJ, van der Harst P, Waagstein F, Hjalmarson Å, Kjekshus J, Balmforth AJ, MERIT-HF Study Group (2013)
An investigation of CYP2D6 genotype and response to metoprolol CR/XL during dose titration in patients with heart failure: a MERIT-HF substudy
Clin Pharmacol Ther, 95 (3), 321-30
PubMed 24193112

Dahl CP, Aukrust P, Nymo SH, Kjekshus J, Cleland JG, McMurray JJ, Wikstrand J, Gullestad L, Ueland T (2013)
Prognostic value of CXCL16 in patients with left ventricular systolic dysfunction and heart failure
Int J Cardiol, 168 (4), 4427-9
PubMed 23714594

Gravning J, Askevold ET, Nymo SH, Ueland T, Wikstrand J, McMurray JJ, Aukrust P, Gullestad L, Kjekshus J, CORONA Study Group (2013)
Prognostic effect of high-sensitive troponin T assessment in elderly patients with chronic heart failure: results from the CORONA trial
Circ Heart Fail, 7 (1), 96-103
PubMed 24284025

Gravning J, Smedsrud MK, Omland T, Eek C, Skulstad H, Aaberge L, Bendz B, Kjekshus J, Mørkrid L, Edvardsen T (2013)
Sensitive troponin assays and N-terminal pro-B-type natriuretic peptide in acute coronary syndrome: prediction of significant coronary lesions and long-term prognosis
Am Heart J, 165 (5), 716-24
PubMed 23622908

Ketchum ES, Dickstein K, Kjekshus J, Pitt B, Wong MF, Linker DT, Levy WC (2013)
The Seattle Post Myocardial Infarction Model (SPIM): prediction of mortality after acute myocardial infarction with left ventricular dysfunction
Eur Heart J Acute Cardiovasc Care, 3 (1), 46-55
PubMed 24562803

Perez AC, Jhund P, Preiss D, Kjekshus J, McMurray JJ (2013)
Effect of rosuvastatin on fatigue in patients with heart failure
J Am Coll Cardiol, 61 (10), 1121-2
PubMed 23473415

Ueland T, Nymo SH, Latini R, McMurray JJ, Kjekshus J, Yndestad A, Fucili A, Grosu A, Masson S, Maggioni AP, Gullestad L, Aukrust P, Investigators of the Controlled Rosuvastatin Multinational Study in Heart Failure (CORONA) trial, Investigators of the GISSI-Heart Failure (GISSI-HF) trial (2013)
CCL21 is associated with fatal outcomes in chronic heart failure: data from CORONA and GISSI-HF trials
Eur J Heart Fail, 15 (7), 747-55
PubMed 23487539

Wethal T, Nedregaard B, Andersen R, Fosså A, Lund MB, Günther A, Kvaløy S, Fosså SD, Kjekshus J (2013)
Atherosclerotic lesions in lymphoma survivors treated with radiotherapy
Radiother Oncol, 110 (3), 448-54
PubMed 24231235

Publications 2012

Askevold ET, Nymo S, Ueland T, Gravning J, Wergeland R, Kjekshus J, Yndestad A, Cleland JG, McMurray JJ, Aukrust P, Gullestad L (2012)
Soluble glycoprotein 130 predicts fatal outcomes in chronic heart failure: analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
Circ Heart Fail, 6 (1), 91-8
PubMed 23230311

Broch K, Ueland T, Nymo SH, Kjekshus J, Hulthe J, Muntendam P, McMurray JJ, Wikstrand J, Cleland JG, Aukrust P, Gullestad L (2012)
Soluble ST2 is associated with adverse outcome in patients with heart failure of ischaemic aetiology
Eur J Heart Fail, 14 (3), 268-77
PubMed 22302661

Gullestad L, Ueland T, Kjekshus J, Nymo SH, Hulthe J, Muntendam P, Adourian A, Böhm M, van Veldhuisen DJ, Komajda M, Cleland JG, Wikstrand J, McMurray JJ, Aukrust P, CORONA Study Group (2012)
Galectin-3 predicts response to statin therapy in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
Eur Heart J, 33 (18), 2290-6
PubMed 22513778

Gullestad L, Ueland T, Kjekshus J, Nymo SH, Hulthe J, Muntendam P, McMurray JJ, Wikstrand J, Aukrust P (2012)
The predictive value of galectin-3 for mortality and cardiovascular events in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)
Am Heart J, 164 (6), 878-83
PubMed 23194488

Inglis SC, Bebchuk J, Al-Suhaim SA, Case J, Pfeffer MA, Solomon SD, Hou YR, Pitt B, Dargie HJ, Ford I, Kjekshus J, Zannad F, Dickstein K, McMurray JJ (2012)
Peripheral artery disease and outcomes after myocardial infarction: an individual-patient meta-analysis of 28,771 patients in CAPRICORN, EPEHESUS, OPTIMAAL and VALIANT
Int J Cardiol, 168 (2), 1094-101
PubMed 23194780

Jaffe LM, Kjekshus J, Gottlieb SS (2012)
Importance and management of chronic sleep apnoea in cardiology
Eur Heart J, 34 (11), 809-15
PubMed 22427382

Kåsin JI, Kjellevand TO, Kjekshus J, Nesheim GB, Wagstaff A (2012)
CT examination of the pericardium and lungs in helicopter pilots exposed to vibration and noise
Aviat Space Environ Med, 83 (9), 858-64
PubMed 22946349

Nymo SH, Ueland T, Askevold ET, Flo TH, Kjekshus J, Hulthe J, Wikstrand J, McMurray J, Van Veldhuisen DJ, Gullestad L, Aukrust P, Yndestad A (2012)
The association between neutrophil gelatinase-associated lipocalin and clinical outcome in chronic heart failure: results from CORONA*
J Intern Med, 271 (5), 436-43
PubMed 22211640

Preiss D, Tikkanen MJ, Welsh P, Ford I, Lovato LC, Elam MB, LaRosa JC, DeMicco DA, Colhoun HM, Goldenberg I, Murphy MJ, MacDonald TM, Pedersen TR, Keech AC, Ridker PM, Kjekshus J, Sattar N, McMurray JJ (2012)
Lipid-modifying therapies and risk of pancreatitis: a meta-analysis
JAMA, 308 (8), 804-11
PubMed 22910758

Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Øie E, Vinge LE, Sjaastad I, Sandanger Ø, Ranheim T, Dickstein K, Kjekshus J, Damås JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P (2012)
The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure
PLoS One, 7 (3), e33038
PubMed 22427939

Publications 2011

Catapano AL, Reiner Z, De Backer G, Graham I, Taskinen MR, Wiklund O, Agewall S, Alegria E, Chapman M, Durrington P, Erdine S, Halcox J, Hobbs R, Kjekshus J, Filardi PP, Riccardi G, Storey RF, Wood D, European Society of Cardiology (ESC), European Atherosclerosis Society (EAS) (2011)
ESC/EAS Guidelines for the management of dyslipidaemias The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
Atherosclerosis, 217 (1), 3-46
PubMed 21882396

European Association for Cardiovascular Prevention & Rehabilitation, Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, Wiklund O, Agewall S, Alegria E, Chapman MJ, Durrington P, Erdine S, Halcox J, Hobbs R, Kjekshus J, Filardi PP, Riccardi G, Storey RF, Wood D, ESC Committee for Practice Guidelines (CPG) 2008-2010 and 2010-2012 Committees (2011)
ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
Eur Heart J, 32 (14), 1769-818
PubMed 21712404

Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS), Catapano AL, Reiner Z, De Backer G, Graham I, Taskinen MR, Wiklund O, Agewall S, Alegria E, Chapman MJ, Durrington P, Erdine S, Halcox J, Hobbs R, Kjekshus J, Perrone Filardi P, Riccardi G, Storey RF, Wood D, ESC Committee for Practice Guidelines 2008-2010 and 2010-2012 Committees (2011)
ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
Atherosclerosis, 217 Suppl 1, S1-44
PubMed 21723445

Ueland T, Dahl CP, Kjekshus J, Hulthe J, Böhm M, Mach F, Goudev A, Lindberg M, Wikstrand J, Aukrust P, Gullestad L (2011)
Osteoprotegerin predicts progression of chronic heart failure: results from CORONA
Circ Heart Fail, 4 (2), 145-52
PubMed 21216833

Publications 2010

Inglis SC, McMurray JJ, Böhm M, Schaufelberger M, van Veldhuisen DJ, Lindberg M, Dunselman P, Hjalmarson A, Kjekshus J, Waagstein F, Wedel H, Wikstrand J, CORONA Study Group (2010)
Intermittent claudication as a predictor of outcome in patients with ischaemic systolic heart failure: analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure trial (CORONA)
Eur J Heart Fail, 12 (7), 698-705
PubMed 20501489

Kim MA, Yang D, Kida K, Molotkova N, Yeo SJ, Varki N, Iwata M, Dalton ND, Peterson KL, Siems WE, Walther T, Cowling RT, Kjekshus J, Greenberg B (2010)
Effects of ACE2 inhibition in the post-myocardial infarction heart
J Card Fail, 16 (9), 777-85
PubMed 20797602

Lorgelly PK, Briggs AH, Wedel H, Dunselman P, Hjalmarson A, Kjekshus J, Waagstein F, Wikstrand J, Jánosi A, van Veldhuisen DJ, Barrios V, Fonseca C, McMurray JJ, CORONA Study Group (2010)
An economic evaluation of rosuvastatin treatment in systolic heart failure: evidence from the CORONA trial
Eur J Heart Fail, 12 (1), 66-74
PubMed 20023047

McMurray JJ, Dunselman P, Wedel H, Cleland JG, Lindberg M, Hjalmarson A, Kjekshus J, Waagstein F, Apetrei E, Barrios V, Böhm M, Kamenský G, Komajda M, Mareev V, Wikstrand J, CORONA Study Group (2010)
Coenzyme Q10, rosuvastatin, and clinical outcomes in heart failure: a pre-specified substudy of CORONA (controlled rosuvastatin multinational study in heart failure)
J Am Coll Cardiol, 56 (15), 1196-204
PubMed 20883926

Sattar N, Preiss D, Murray HM, Welsh P, Buckley BM, de Craen AJ, Seshasai SR, McMurray JJ, Freeman DJ, Jukema JW, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Shepherd J, Davis BR, Pressel SL, Marchioli R, Marfisi RM, Maggioni AP, Tavazzi L, Tognoni G, Kjekshus J, Pedersen TR, Cook TJ et al. (2010)
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials
Lancet, 375 (9716), 735-42
PubMed 20167359

Wethal T, Haugnes HS, Kjekshus J, Småstuen MC, Ueland T, Aukrust P, Fosså SD (2010)
C-reactive protein; a potential marker of second cancer and cardiovascular disease in testicular cancer survivors?
Eur J Cancer, 46 (18), 3425-33
PubMed 20832295

Publications 2009

Andersen R, Wethal T, Günther A, Fosså A, Edvardsen T, Fosså SD, Kjekshus J (2009)
Relation of coronary artery calcium score to premature coronary artery disease in survivors >15 years of Hodgkin's lymphoma
Am J Cardiol, 105 (2), 149-52
PubMed 20102909

Anker SD, Voors A, Okonko D, Clark AL, James MK, von Haehling S, Kjekshus J, Ponikowski P, Dickstein K, OPTIMAAL Investigators (2009)
Prevalence, incidence, and prognostic value of anaemia in patients after an acute myocardial infarction: data from the OPTIMAAL trial
Eur Heart J, 30 (11), 1331-9
PubMed 19383732

Cleland JG, McMurray JJ, Kjekshus J, Cornel JH, Dunselman P, Fonseca C, Hjalmarson A, Korewicki J, Lindberg M, Ranjith N, van Veldhuisen DJ, Waagstein F, Wedel H, Wikstrand J, CORONA Study Group (2009)
Plasma concentration of amino-terminal pro-brain natriuretic peptide in chronic heart failure: prediction of cardiovascular events and interaction with the effects of rosuvastatin: a report from CORONA (Controlled Rosuvastatin Multinational Trial in Heart Failure)
J Am Coll Cardiol, 54 (20), 1850-9
PubMed 19892235

Kjekshus J (2009)
Is there a heart rate paradox--demystification of the myths?
J Intern Med, 266 (3), 242-7
PubMed 19702792

Kåsin JI, Kjekshus J, Aukrust P, Mollnes TE, Wagstaff A (2009)
A helicopter flight does not induce significant changes in systemic biomarker profiles
Scand J Clin Lab Invest, 69 (4), 462-74
PubMed 19333819

McMurray JJ, Kjekshus J, Gullestad L, Dunselman P, Hjalmarson A, Wedel H, Lindberg M, Waagstein F, Grande P, Hradec J, Kamenský G, Korewicki J, Kuusi T, Mach F, Ranjith N, Wikstrand J, CORONA Study Group (2009)
Effects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): a retrospective analysis
Circulation, 120 (22), 2188-96
PubMed 19917888

Wedel H, McMurray JJ, Lindberg M, Wikstrand J, Cleland JG, Cornel JH, Dunselman P, Hjalmarson A, Kjekshus J, Komajda M, Kuusi T, Vanhaecke J, Waagstein F, CORONA Study Group (2009)
Predictors of fatal and non-fatal outcomes in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): incremental value of apolipoprotein A-1, high-sensitivity C-reactive peptide and N-terminal pro B-type natriuretic peptide
Eur J Heart Fail, 11 (3), 281-91
PubMed 19168876

Wethal T, Lund MB, Edvardsen T, Fosså SD, Pripp AH, Holte H, Kjekshus J, Fosså A (2009)
Valvular dysfunction and left ventricular changes in Hodgkin's lymphoma survivors. A longitudinal study
Br J Cancer, 101 (4), 575-81
PubMed 19623176

Yndestad A, Landrø L, Ueland T, Dahl CP, Flo TH, Vinge LE, Espevik T, Frøland SS, Husberg C, Christensen G, Dickstein K, Kjekshus J, Øie E, Gullestad L, Aukrust P (2009)
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure
Eur Heart J, 30 (10), 1229-36
PubMed 19329498

Publications 2008

Ghali JK, Wikstrand J, Van Veldhuisen DJ, Fagerberg B, Goldstein S, Hjalmarson A, Johansson P, Kjekshus J, Ohlsson L, Samuelsson O, Waagstein F, Wedel H, MERIT-HF Study Group (2008)
The influence of renal function on clinical outcome and response to beta-blockade in systolic heart failure: insights from Metoprolol CR/XL Randomized Intervention Trial in Chronic HF (MERIT-HF)
J Card Fail, 15 (4), 310-8
PubMed 19398079

Gravning J, Kjekshus J (2008)
The perfect biomarker in acute coronary syndrome: a challenge for diagnosis, prognosis, and treatment
Eur Heart J, 29 (23), 2827-8
PubMed 18957473

Gravning J, Ueland T, Mørkrid L, Endresen K, Aaberge L, Kjekshus J (2008)
Different prognostic importance of elevated troponin I after percutaneous coronary intervention in acute coronary syndrome and stable angina pectoris
Scand Cardiovasc J, 42 (3), 214-21
PubMed 18569954

Huskey J, Lindenfeld J, Cook T, Targher G, Kendrick J, Kjekshus J, Pedersen T, Chonchol M (2008)
Effect of simvastatin on kidney function loss in patients with coronary heart disease: findings from the Scandinavian Simvastatin Survival Study (4S)
Atherosclerosis, 205 (1), 202-6
PubMed 19124121

Kjekshus J (2008)
Risk associated with statin treatment
J Am Coll Cardiol, 51 (1), 91; author reply 92
PubMed 18174047

Kjekshus J (2008)
What are the effects of patient age and blood pressure on the cholesterol-related risk of vascular mortality?
Nat Clin Pract Cardiovasc Med, 5 (6), 310-1
PubMed 18446135

Kjekshus J, McMurray JJV, Wikstrand J (2008)
Rosuvastatin in older patients with systolic heart failure - Reply
N. Engl. J. Med., 358 (12), 1301

Publications 2007

Chonchol M, Cook T, Kjekshus J, Pedersen TR, Lindenfeld J (2007)
Simvastatin for secondary prevention of all-cause mortality and major coronary events in patients with mild chronic renal insufficiency
Am J Kidney Dis, 49 (3), 373-82
PubMed 17336698

Kjekshus J (2007)
Prescription of beta-blockers in patients with advanced heart failure and preserved left ventricular ejection fraction. Clinical implications and survival
Eur J Heart Fail, 9 (9), 962; author reply 962-3
PubMed 17652021

Kjekshus J, Apetrei E, Barrios V, Böhm M, Cleland JG, Cornel JH, Dunselman P, Fonseca C, Goudev A, Grande P, Gullestad L, Hjalmarson A, Hradec J, Jánosi A, Kamenský G, Komajda M, Korewicki J, Kuusi T, Mach F, Mareev V, McMurray JJ, Ranjith N, Schaufelberger M, Vanhaecke J, van Veldhuisen DJ et al. (2007)
Rosuvastatin in older patients with systolic heart failure
N Engl J Med, 357 (22), 2248-61
PubMed 17984166

Wethal T, Kjekshus J, Røislien J, Ueland T, Andreassen AK, Wergeland R, Aukrust P, Fosså SD (2007)
Treatment-related differences in cardiovascular risk factors in long-term survivors of testicular cancer
J Cancer Surviv, 1 (1), 8-16
PubMed 18648940

Publications 2006

Damås JK, Smith C, Øie E, Fevang B, Halvorsen B, Waehre T, Boullier A, Breland U, Yndestad A, Ovchinnikova O, Robertson AK, Sandberg WJ, Kjekshus J, Taskén K, Frøland SS, Gullestad L, Hansson GK, Quehenberger O, Aukrust P (2006)
Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization
Arterioscler Thromb Vasc Biol, 27 (3), 614-20
PubMed 17170367

Estensen ME, Hognestad A, Syversen U, Squire I, Ng L, Kjekshus J, Dickstein K, Omland T (2006)
Prognostic value of plasma chromogranin A levels in patients with complicated myocardial infarction
Am Heart J, 152 (5), 927.e1-6
PubMed 17070161

Gravning J, Vege A, Kjekshus J (2006)
[Unexpected sudden death after percutaneous coronary intervention]
Tidsskr Nor Laegeforen, 126 (16), 2111-3
PubMed 16960998

Holm T, Ueland T, Halvorsen B, Hognestad A, Holm AG, Wergeland R, Gullestad L, Aukrust P, Kjekshus J (2006)
A protective anti-inflammatory phenotype in high-risk individuals who do not develop coronary artery disease
J Am Coll Cardiol, 47 (5), 1085-6
PubMed 16516099

Kennedy LM, Anker SD, Kjekshus J, Cook TJ, Willenheimer R (2006)
Impact of neurohormonal blockade on association between body mass index and mortality
Int J Cardiol, 119 (1), 33-40
PubMed 17052777

Ueland T, Espevik T, Kjekshus J, Gullestad L, Omland T, Squire IB, Frøland SS, Mollnes TE, Dickstein K, Aukrust P (2006)
Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarction
J Card Fail, 12 (8), 659-63
PubMed 17045187

van Veldhuisen DJ, Aass H, El Allaf D, Dunselman PH, Gullestad L, Halinen M, Kjekshus J, Ohlsson L, Wedel H, Wikstrand J, MERIT-HF Study Group (2006)
Presence and development of atrial fibrillation in chronic heart failure. Experiences from the MERIT-HF Study
Eur J Heart Fail, 8 (5), 539-46
PubMed 16567126

Waaler BA, Hisdal J, Ihlen H, Kjekshus J (2006)
Mechanisms behind the postprandial increase in cardiac output: a clue obtained from transplanted hearts
Eur J Appl Physiol, 97 (5), 516-20
PubMed 16718506

Publications 2005

Böhm M, Hjalmarson A, Kjekshus J, Laufs U, McMurray J, van Veldhuisen DJ (2005)
Heart failure and statins--why do we need a clinical trial?
Z Kardiol, 94 (4), 223-30
PubMed 15803258

Deedwania PC, Giles TD, Klibaner M, Ghali JK, Herlitz J, Hildebrandt P, Kjekshus J, Spinar J, Vitovec J, Stanbrook H, Wikstrand J, MERIT-HF Study Group (2005)
Efficacy, safety and tolerability of metoprolol CR/XL in patients with diabetes and chronic heart failure: experiences from MERIT-HF
Am Heart J, 149 (1), 159-67
PubMed 15660048

Dickstein K, Gleim GW, Snapinn S, James MK, Kjekshus J, OPTIMAAL Study Group (2005)
The impact of morbid events on survival following hospitalization for complicated myocardial infarction
Eur J Heart Fail, 8 (1), 74-80
PubMed 16081319

Gullestad L, Kjekshus J, Damås JK, Ueland T, Yndestad A, Aukrust P (2005)
Agents targeting inflammation in heart failure
Expert Opin Investig Drugs, 14 (5), 557-66
PubMed 15926863

Gullestad L, Ueland T, Fjeld JG, Holt E, Gundersen T, Breivik K, Følling M, Hodt A, Skårdal R, Kjekshus J, Andreassen A, Kjekshus E, Wergeland R, Yndestad A, Frøland SS, Semb AG, Aukrust P (2005)
Effect of thalidomide on cardiac remodeling in chronic heart failure: results of a double-blind, placebo-controlled study
Circulation, 112 (22), 3408-14
PubMed 16301340

Gullestad L, Wikstrand J, Deedwania P, Hjalmarson A, Egstrup K, Elkayam U, Gottlieb S, Rashkow A, Wedel H, Bermann G, Kjekshus J, MERIT-HF Study Group (2005)
What resting heart rate should one aim for when treating patients with heart failure with a beta-blocker? Experiences from the Metoprolol Controlled Release/Extended Release Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF)
J Am Coll Cardiol, 45 (2), 252-9
PubMed 15653024

Gurantz D, Yndestad A, Halvorsen B, Lunde OV, Omens JH, Ueland T, Aukrust P, Moore CD, Kjekshus J, Greenberg BH (2005)
Etanercept or intravenous immunoglobulin attenuates expression of genes involved in post-myocardial infarction remodeling
Cardiovasc Res, 67 (1), 106-15
PubMed 15949474

Hognestad A, Holm T, Simonsen S, Kjekshus J, Andreassen AK (2005)
Serial measurements of peripheral vascular reactivity and exercise capacity in congestive heart failure and after heart transplantation
J Card Fail, 11 (6), 447-54
PubMed 16105636

Kjekshus J, Dunselman P, Blideskog M, Eskilson C, Hjalmarson A, McMurray JV, Waagstein F, Wedel H, Wessman P, Wikstrand J, CORONA Study Group (2005)
A statin in the treatment of heart failure? Controlled rosuvastatin multinational study in heart failure (CORONA): study design and baseline characteristics
Eur J Heart Fail, 7 (6), 1059-69
PubMed 16227145

Orn S, Cleland JG, Romo M, Kjekshus J, Dickstein K (2005)
Recurrent infarction causes the most deaths following myocardial infarction with left ventricular dysfunction
Am J Med, 118 (7), 752-8
PubMed 15989909

Ueland T, Aukrust P, Yndestad A, Otterdal K, Frøland SS, Dickstein K, Kjekshus J, Gullestad L, Damås JK (2005)
Soluble CD40 ligand in acute and chronic heart failure
Eur Heart J, 26 (11), 1101-7
PubMed 15716285

Ueland T, Kjekshus J, Frøland SS, Omland T, Squire IB, Gullestad L, Dickstein K, Aukrust P (2005)
Plasma levels of soluble tumor necrosis factor receptor type I during the acute phase following complicated myocardial infarction predicts survival in high-risk patients
J Am Coll Cardiol, 46 (11), 2018-21
PubMed 16325035

Publications 2004

Girman CJ, Rhodes T, Mercuri M, Pyörälä K, Kjekshus J, Pedersen TR, Beere PA, Gotto AM, Clearfield M, 4S Group and the AFCAPS/TexCAPS Research Group (2004)
The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)
Am J Cardiol, 93 (2), 136-41
PubMed 14715336

Gullestad L, Myers J, Edvardsen T, Kjekshus J, Geiran O, Simonsen S (2004)
Predictors of exercise capacity and the impact of angiographic coronary artery disease in heart transplant recipients
Am Heart J, 147 (1), 49-54
PubMed 14691418

Hognestad A, Dickstein K, Myhre E, Snapinn S, Kjekshus J, OPTIMAAL Investigators (2004)
Effect of combined statin and beta-blocker treatment on one-year morbidity and mortality after acute myocardial infarction associated with heart failure
Am J Cardiol, 93 (5), 603-6
PubMed 14996587

Pedersen TR, Kjekshus J, Berg K, Haghfelt T, Faergeman O, Faergeman G, Pyörälä K, Miettinen T, Wilhelmsen L, Olsson AG, Wedel H, Scandinavian Simvastatin Survival Study Group (2004)
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). 1994
Atheroscler Suppl, 5 (3), 81-7
PubMed 15531279

Pedersen TR, Olsson AG, Faergeman O, Kjekshus J, Wedel H, Berg K, Wilhelmsen L, Haghfelt T, Thorgeirsson G, Pyörälä K, Miettinen T, Christophersen B, Tobert JA, Musliner TA, Cook TJ, Scandinavian Simavastatin Survival Study Group (2004)
Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S). 1998
Atheroscler Suppl, 5 (3), 99-106
PubMed 15531282

Pyörälä K, Ballantyne CM, Gumbiner B, Lee MW, Shah A, Davies MJ, Mitchel YB, Pedersen TR, Kjekshus J, Scandinavian Simvastatin Survival Study (4S) (2004)
Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: subgroup analyses of the Scandinavian Simvastatin Survival Study (4S)
Diabetes Care, 27 (7), 1735-40
PubMed 15220255

Strandberg TE, Pyörälä K, Cook TJ, Wilhelmsen L, Faergeman O, Thorgeirsson G, Pedersen TR, Kjekshus J, 4S Group (2004)
Mortality and incidence of cancer during 10-year follow-up of the Scandinavian Simvastatin Survival Study (4S)
Lancet, 364 (9436), 771-7
PubMed 15337403

Ueland T, Jemtland R, Godang K, Kjekshus J, Hognestad A, Omland T, Squire IB, Gullestad L, Bollerslev J, Dickstein K, Aukrust P (2004)
Prognostic value of osteoprotegerin in heart failure after acute myocardial infarction
J Am Coll Cardiol, 44 (10), 1970-6
PubMed 15542278

Publications 2003

Dunselman P, Hjalmarson A, Kjekshus J, McMurray J, Waagstein F, Executive Committee of the CORONA trial (2003)
The statin wars
Lancet, 362 (9398), 1854; discussion 1856
PubMed 14654327

Gullestad L, Kjekshus J (2003)
[Use of beta-blockaders in heart failure]
Tidsskr Nor Laegeforen, 123 (5), 651-2
PubMed 12683197

Hall C, Ihlen H, Bonarjee V, Dickstein K, Kjekshus J (2003)
N-terminal proatrial natriuretic peptide in primary care: relation to echocardiographic indices of cardiac function in mild to moderate cardiac disease
Int J Cardiol, 89 (2-3), 197-205
PubMed 12767543

Holm T, Damås JK, Holven K, Nordøy I, Brosstad FR, Ueland T, Währe T, Kjekshus J, Frøland SS, Eiken HG, Solum NO, Gullestad L, Nenseter M, Aukrust P (2003)
CXC-chemokines in coronary artery disease: possible pathogenic role of interactions between oxidized low-density lipoprotein, platelets and peripheral blood mononuclear cells
J Thromb Haemost, 1 (2), 257-62
PubMed 12871498

Wikstrand J, Fagerberg B, Goldstein S, Kjekshus J, Wedel H (2003)
COMET: a proposed mechanism of action to explain the results and concerns about dose
Lancet, 362 (9389), 1076-7; author reply 1077-8
PubMed 14522542

Wikstrand J, Wedel H, Ghali J, Deedwania P, Fagerberg B, Goldstein S, Gottlieb S, Hjalmarson A, Kjekshus J, Waagstein F (2003)
How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF)
Card Electrophysiol Rev, 7 (3), 264-75
PubMed 14739726

Publications 2002

Ballantyne CM, Olsson AG, Cook TJ, Mercuri MF, Pedersen TR, Kjekshus J (2002)
Low high-density lipoprotein cholesterol and response to simvastatin therapy in Scandinavian Simvastatin Survival Study (4S) - Response
Circulation, 106 (2), E8

Crea F, Monaco C, Lanza GA, Maggi E, Ginnetti F, Cianflone D, Niccoli G, Cook T, Bellomo G, Kjekshus J (2002)
Inflammatory predictors of mortality in the Scandinavian Simvastatin Survival Study
Clin Cardiol, 25 (10), 461-6
PubMed 12375804

Dickstein K, Kjekshus J (2002)
The OPTIMAL trial: losartan or captopril after acute myocardial infarction - Reply
Lancet, 360 (9348), 1885

Dickstein K, Kjekshus J, OPTIMAAL Steering Committee of the OPTIMAAL Study Group (2002)
Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan
Lancet, 360 (9335), 752-60
PubMed 12241832

Gottlieb SS, Fisher ML, Kjekshus J, Deedwania P, Gullestad L, Vitovec J, Wikstrand J, MERIT-HF Investigators (2002)
Tolerability of beta-blocker initiation and titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)
Circulation, 105 (10), 1182-8
PubMed 11889011

Holm T, Aukrust P, Aagaard E, Ueland T, Haugstad TS, Kjekshus J, Simonsen S, Frøland SS, Gullestad L, Andreassen AK (2002)
Hypertension in relation to nitric oxide, asymmetric dimethylarginine, and inflammation: different patterns in heart transplant recipients and individuals with essential hypertension
Transplantation, 74 (10), 1395-400
PubMed 12451238

Qi W, Mathisen P, Kjekshus J, Simonsen S, Endresen K, Bjørnerheim R, Hall C (2002)
The effect of aortic valve replacement on N-terminal natriuretic propeptides in patients with aortic stenosis
Clin Cardiol, 25 (4), 174-80
PubMed 12000075

Waehre T, Halvorsen B, Damås JK, Yndestad A, Brosstad F, Gullestad L, Kjekshus J, Frøland SS, Aukrust P (2002)
Inflammatory imbalance between IL-10 and TNFalpha in unstable angina potential plaque stabilizing effects of IL-10
Eur J Clin Invest, 32 (11), 803-10
PubMed 12423320

Wikstrand J, Hjalmarson A, Waagstein F, Fagerberg B, Goldstein S, Kjekshus J, Wedel H, MERIT-HF Study Group (2002)
Dose of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart failure (MERIT-HF)
J Am Coll Cardiol, 40 (3), 491-8
PubMed 12142116

Wikstrand J, Hjalmarson A, Waagstein F, Fagerberg B, Goldstein S, Kjekshus J, Wedel H, MERIT-HF Study Grp (2002)
Dose of Metoprolol CR/XL and clinical outcomes in patients with heart failure - Analysis of the experience in Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF)
J. Am. Coll. Cardiol., 40 (3), PII S0735-1097(02)01970-8-498

Publications 2001

Andreassen AK, Madsen S, Kjekshus J, Simonsen S (2001)
[Inhalation of a prostacyclin analog (iloprost) in primary and secondary pulmonary hypertension]
Tidsskr Nor Laegeforen, 121 (10), 1220-3
PubMed 11402748

Aukrust P, Gullestad L, Aass H, Fjeld JG, Wikeby L, Andreassen AK, Ihlen H, Simonsen S, Kjekshus J, Nitter-Hauge S, Ueland T, Froland SS (2001)
Increase in anti-inflammatory cytokine levels in chronic heart failure: A measure of treatment success or failure? Response
Circulation, 104 (18), E97-E98

Ballantyne CM, Olsson AG, Cook TJ, Mercuri MF, Pedersen TR, Kjekshus J (2001)
Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S
Circulation, 104 (25), 3046-51
PubMed 11748098

Dickstein K, Kjekshus J, OPTIMAAL Trial Steering Committee and Investigators. Optimal Trial in Myocardial Infarction with the Angiotensin II Antagonist Losartan (2001)
Comparison of baseline data, initial course, and management: losartan versus captopril following acute myocardial infarction (The OPTIMAAL Trial). OPTIMAAL Trial Steering Committee and Investigators. Optimal Trial in Myocardial Infarction with the Angiotensin II Antagonist Losartan
Am J Cardiol, 87 (6), 766-71, A7
PubMed 11249900

Goldstein S, Fagerberg B, Hjalmarson A, Kjekshus J, Waagstein F, Wedel H, Wikstrand J, MERIT-HF Study Group (2001)
Metoprolol controlled release/extended release in patients with severe heart failure: analysis of the experience in the MERIT-HF study
J Am Coll Cardiol, 38 (4), 932-8
PubMed 11583861

Gullestad L, Manhenke C, Aarsland T, Skårdal R, Fagertun H, Wikstrand J, Kjekshus J (2001)
Effect of metoprolol CR/XL on exercise tolerance in chronic heart failure - a substudy to the MERIT-HF trial
Eur J Heart Fail, 3 (4), 463-8
PubMed 11511433

Gullestad L, Ueland T, Brunsvig A, Kjekshus J, Simonsen S, Frøland SS, Aukrust P (2001)
Effect of metoprolol on cytokine levels in chronic heart failure--a substudy in the Metoprolol Controlled-Release Randomised Intervention Trial in Heart Failure (MERIT-HF)
Am Heart J, 141 (3), 418-21
PubMed 11231439

Gullestad L, Aass H, Andreassen AK, Ihlen H, Simonsen S, Kjekshus J, Wikeby L, Nitter-Hauge S, Fjeld JG, Lien E, Ueland T, Frøland SS, Aukrust P (2001)
[Immunomodulating treatment in advanced heart failure--effect of intravenous immunoglobulin]
Tidsskr Nor Laegeforen, 121 (16), 1902-7
PubMed 11488180

Gullestad L, Aass H, Fjeld JG, Wikeby L, Andreassen AK, Ihlen H, Simonsen S, Kjekshus J, Nitter-Hauge S, Ueland T, Lien E, Frøland SS, Aukrust P (2001)
Immunomodulating therapy with intravenous immunoglobulin in patients with chronic heart failure
Circulation, 103 (2), 220-5
PubMed 11208680

Holm T, Andreassen AK, Aukrust P, Andersen K, Geiran OR, Kjekshus J, Simonsen S, Gullestad L (2001)
Omega-3 fatty acids improve blood pressure control and preserve renal function in hypertensive heart transplant recipients
Eur Heart J, 22 (5), 428-36
PubMed 11207085

Holm T, Andreassen AK, Ueland T, Kjekshus J, Frøland SS, Kjekshus E, Simonsen S, Aukrust P, Gullestad L (2001)
Effect of pravastatin on plasma markers of inflammation and peripheral endothelial function in male heart transplant recipients
Am J Cardiol, 87 (6), 815-8, A9
PubMed 11249916

Holm T, Berge RK, Andreassen AK, Ueland T, Kjekshus J, Simonsen S, Frøland S, Gullestad L, Aukrust P (2001)
Omega-3 fatty acids enhance tumor necrosis factor-alpha levels in heart transplant recipients
Transplantation, 72 (4), 706-11
PubMed 11544435

Holven KB, Holm T, Aukrust P, Christensen B, Kjekshus J, Andreassen AK, Gullestad L, Hagve TA, Svilaas A, Ose L, Nenseter MS (2001)
Effect of folic acid treatment on endothelium-dependent vasodilation and nitric oxide-derived end products in hyperhomocysteinemic subjects
Am J Med, 110 (7), 536-42
PubMed 11343667

Kjekshus J (2001)
Debate: Statins should be used in patients with heart failure
Curr Control Trials Cardiovasc Med, 2 (6), 268-270
PubMed 11806812

Moer R, Myreng Y, Mølstad P, Albertsson P, Gunnes P, Lindvall B, Wiseth R, Ytre-Arne K, Kjekshus J, Golf S (2001)
Stenting in small coronary arteries (SISCA) trial. A randomized comparison between balloon angioplasty and the heparin-coated beStent
J Am Coll Cardiol, 38 (6), 1598-603
PubMed 11704369

Qi W, Mathisen P, Kjekshus J, Simonsen S, Bjørnerheim R, Endresen K, Hall C (2001)
Natriuretic peptides in patients with aortic stenosis
Am Heart J, 142 (4), 725-32
PubMed 11579366

Wedel H, Demets D, Deedwania P, Fagerberg B, Goldstein S, Gottlieb S, Hjalmarson A, Kjekshus J, Waagstein F, Wikstrand J, MERIT-HF Study Group (2001)
Challenges of subgroup analyses in multinational clinical trials: experiences from the MERIT-HF trial
Am Heart J, 142 (3), 502-11
PubMed 11526365

Wilhelmsen L, Pyörälä K, Wedel H, Cook T, Pedersen T, Kjekshus J (2001)
Risk factors for a major coronary event after myocardial infarction in the Scandinavian Simvastatin Survival Study (4S). Impact of predicted risk on the benefit of cholesterol-lowering treatment
Eur Heart J, 22 (13), 1119-27
PubMed 11428852

Publications 2000

Hjalmarson A, Goldstein S, Fagerberg B, Wedel H, Waagstein F, Kjekshus J, Wikstrand J, El Allaf D, Vítovec J, Aldershvile J, Halinen M, Dietz R, Neuhaus KL, Jánosi A, Thorgeirsson G, Dunselman PH, Gullestad L, Kuch J, Herlitz J, Rickenbacher P, Ball S, Gottlieb S, Deedwania P (2000)
Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF). MERIT-HF Study Group
JAMA, 283 (10), 1295-302
PubMed 10714728

Kjekshus J (2000)
Distribution of myocardial injury and its relation to epicardial ST-segment change after coronary occlusion in the dog
Cardiovasc Res, 45 (1), 107-10
PubMed 10728320

Kjekshus J (2000)
Distribution of myocardial injury and its relation to epicardial ST-segment changes after coronary artery occlusion in the dog
Cardiovasc. Res., 45 (1), 109-110

Latini R, Tognoni G, Maggioni AP, Baigent C, Braunwald E, Chen ZM, Collins R, Flather M, Franzosi MG, Kjekshus J, Køber L, Liu LS, Peto R, Pfeffer M, Pizzetti F, Santoro E, Sleight P, Swedberg K, Tavazzi L, Wang W, Yusuf S (2000)
Clinical effects of early angiotensin-converting enzyme inhibitor treatment for acute myocardial infarction are similar in the presence and absence of aspirin: systematic overview of individual data from 96,712 randomized patients. Angiotensin-converting Enzyme Inhibitor Myocardial Infarction Collaborative Group
J Am Coll Cardiol, 35 (7), 1801-7
PubMed 10841227

Pedersen TR, Kjekshus J (2000)
Statin drugs and the risk of fracture
JAMA-J. Am. Med. Assoc., 284 (15), 1921-1922

Pedersen TR, Wilhelmsen L, Faergeman O, Strandberg TE, Thorgeirsson G, Troedsson L, Kristianson J, Berg K, Cook TJ, Haghfelt T, Kjekshus J, Miettinen T, Olsson AG, Pyörälä K, Wedel H (2000)
Follow-up study of patients randomized in the Scandinavian simvastatin survival study (4S) of cholesterol lowering
Am J Cardiol, 86 (3), 257-62
PubMed 10922429

Qi W, Kjekshus J, Hall C (2000)
Differential responses of plasma atrial and brain natriuretic peptides to acute alteration in atrial pressure in pigs
Scand J Clin Lab Invest, 60 (1), 55-63
PubMed 10757454

Publications 1999

Dickstein K, Kjekshus J (1999)
Comparison of the effects of losartan and captopril on mortality in patients after acute myocardial infarction: the OPTIMAAL trial design. Optimal Therapy in Myocardial Infarction with the Angiotensin II Antagonist Losartan
Am J Cardiol, 83 (4), 477-81
PubMed 10073846

Gullestad L, Bjørnerheim R, Offstad J, Endresen K, Forfang K, Kjekshus J, Hansteen V (1999)
[Current use of beta-blockers in coronary artery disease]
Tidsskr Nor Laegeforen, 119 (1), 24-8
PubMed 10025200

Haffner SM, Alexander CM, Cook TJ, Boccuzzi SJ, Musliner TA, Pedersen TR, Kjekshus J, Pyörälä K (1999)
Reduced coronary events in simvastatin-treated patients with coronary heart disease and diabetes or impaired fasting glucose levels: subgroup analyses in the Scandinavian Simvastatin Survival Study
Arch Intern Med, 159 (22), 2661-7
PubMed 10597756

Herman WH, Alexander CM, Cook JR, Boccuzzi SJ, Musliner TA, Pedersen TR, Kjekshus J, Pyörälä K (1999)
Effect of simvastatin treatment on cardiovascular resource utilization in impaired fasting glucose and diabetes. Findings from the Scandinavian Simvastatin Survival Study
Diabetes Care, 22 (11), 1771-8
PubMed 10546006

Kjekshus J, Gullestad L (1999)
Heart rate as a therapeutic target in heart failure
Eur. Heart J. Suppl., 1 (H), H64-H69

Swedberg K, Kjekshus J, Snapinn S (1999)
Long-term survival in severe heart failure in patients treated with enalapril. Ten year follow-up of CONSENSUS I
Eur Heart J, 20 (2), 136-9
PubMed 10099910

Westheim A, Dickstein K, Gundersen T, Hole T, Kjekshus J, Myhre ES, Rønnevik PK, Samstad S, Smith P (1999)
[Chronic heart failure--suggestion to a management program]
Tidsskr Nor Laegeforen, 119 (23), 3427-31
PubMed 10553340

Publications 1998

Andreassen AK, Kvernebo K, Jørgensen B, Simonsen S, Kjekshus J, Gullestad L (1998)
Exercise capacity in heart transplant recipients: relation to impaired endothelium-dependent vasodilation of the peripheral microcirculation
Am Heart J, 136 (2), 320-8
PubMed 9704697

Aukrust P, Ueland T, Müller F, Andreassen AK, Nordøy I, Aas H, Kjekshus J, Simonsen S, Frøland SS, Gullestad L (1998)
Elevated circulating levels of C-C chemokines in patients with congestive heart failure
Circulation, 97 (12), 1136-43
PubMed 9537339

Braekken SK, Endresen K, Russell D, Brucher R, Kjekshus J (1998)
Influence of guidewire and catheter type on the frequency of cerebral microembolic signals during left heart catheterization
Am J Cardiol, 82 (5), 632-7
PubMed 9732893

Faergeman O, Kjekshus J, Cook T, Pyörälä K, Wilhelmsen L, Thorgeirsson G, Pedersen TR (1998)
Differences in the treatment of coronary heart disease between countries as revealed in the Scandinavian Simvastatin Survival Study (4S)
Eur Heart J, 19 (10), 1531-7
PubMed 9820992

Gullestad L, Haywood G, Aass H, Ross H, Yee G, Ueland T, Geiran O, Kjekshus J, Simonsen S, Bishopric N, Fowler M (1998)
Angiotensin II receptor subtype AT1 and AT2 expression after heart transplantation
Cardiovasc Res, 38 (2), 340-7
PubMed 9709394

Gullestad L, Aass H, Ross H, Ueland T, Geiran O, Kjekshus J, Simonsen S, Fowler M, Kobilka B (1998)
Neuropeptide Y receptor 1 (NPY-Y1) expression in human heart failure and heart transplantation
J Auton Nerv Syst, 70 (1-2), 84-91
PubMed 9686908

Klinge R, Hystad M, Kjekshus J, Karlberg BE, Djøseland O, Aakvaag A, Hall C (1998)
An experimental study of cardiac natriuretic peptides as markers of development of congestive heart failure
Scand J Clin Lab Invest, 58 (8), 683-91
PubMed 10088206

Pedersen TR, Kjekshus J, Pyörälä K, Olsson AG, Cook TJ, Musliner TA, Tobert JA, Haghfelt T (1998)
Effect of simvastatin on ischemic signs and symptoms in the Scandinavian simvastatin survival study (4S)
Am J Cardiol, 81 (3), 333-5
PubMed 9468077

Pedersen TR, Olsson AG, Faergeman O, Kjekshus J, Wedel H, Berg K, Wilhelmsen L, Haghfelt T, Thorgeirsson G, Pyörälä K, Miettinen T, Christophersen B, Tobert JA, Musliner TA, Cook TJ (1998)
Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S)
Circulation, 97 (15), 1453-60
PubMed 9576425

Rodevand O, Bjornerheim R, Aakhus S, Kjekshus J (1998)
Left ventricular volumes assessed by different new three-dimensional echocardiographic methods and ordinary biplane technique
Int J Card Imaging, 14 (1), 55-63
PubMed 9559379

Sirnes PA, Golf S, Myreng Y, Mølstad P, Albertsson P, Mangschau A, Endresen K, Kjekshus J (1998)
Sustained benefit of stenting chronic coronary occlusion: long-term clinical follow-up of the Stenting in Chronic Coronary Occlusion (SICCO) study
J Am Coll Cardiol, 32 (2), 305-10
PubMed 9708454

Publications 1997

Berg K, Dahlén G, Christophersen B, Cook T, Kjekshus J, Pedersen T (1997)
Lp(a) lipoprotein level predicts survival and major coronary events in the Scandinavian Simvastatin Survival Study
Clin Genet, 52 (5), 254-61
PubMed 9520115

Faergeman O, Kjekshus J (1997)
[Cholesterol depression prevents heart disease]
Ugeskr Laeger, 159 (15), 2193
PubMed 9148540

Gullestad L, Myers J, Bjornerheim R, Berg KJ, Djoseland O, Hall C, Lund K, Kjekshus J, Simonsen S (1997)
Gas exchange and neurohumoral response to exercise: influence of the exercise protocol
Med Sci Sports Exerc, 29 (4), 496-502
PubMed 9107632

Gundersen T, Dickstein K, Hole T, Kjekshus J, Myhre ES, Rønnevik P, Smith P, Westheim A (1997)
[Treatment of heart failure with beta-blockaders]
Tidsskr Nor Laegeforen, 117 (4), 526-8
PubMed 9148453

Hole T, Dickstein K, Gundersen T, Kjekshus J, Myhre ES, Rønnevik PK, Westheim AS (1997)
[Calcium channel blockers in heart failure]
Tidsskr Nor Laegeforen, 117 (16), 2329-32
PubMed 9265278

Johannesson M, Jönsson B, Kjekshus J, Olsson AG, Pedersen TR, Wedel H (1997)
Cost effectiveness of simvastatin treatment to lower cholesterol levels in patients with coronary heart disease. Scandinavian Simvastatin Survival Study Group
N Engl J Med, 336 (5), 332-6
PubMed 9011785

Kjekshus J (1997)
[Prevention--are we not good enough?]
Tidsskr Nor Laegeforen, 117 (16), 2293
PubMed 9265266

Kjekshus J (1997)
[Lipid reduction--benefit without risk?]
Tidsskr Nor Laegeforen, 117 (22), 3184-5
PubMed 9411850

Kjekshus J, Pedersen TR (1997)
Use of statins. Cost effectiveness was studied in 4S study
BMJ, 315 (7122), 1619-20
PubMed 9437297

Kjekshus J, Pedersen TR, Olsson AG, Faergeman O, Pyörälä K (1997)
The effects of simvastatin on the incidence of heart failure in patients with coronary heart disease
J Card Fail, 3 (4), 249-54
PubMed 9547437

Miettinen TA, Pyörälä K, Olsson AG, Musliner TA, Cook TJ, Faergeman O, Berg K, Pedersen T, Kjekshus J (1997)
Cholesterol-lowering therapy in women and elderly patients with myocardial infarction or angina pectoris: findings from the Scandinavian Simvastatin Survival Study (4S)
Circulation, 96 (12), 4211-8
PubMed 9416884

Nguyen KN, Aursnes I, Kjekshus J (1997)
Interaction between enalapril and aspirin on mortality after acute myocardial infarction: subgroup analysis of the Cooperative New Scandinavian Enalapril Survival Study II (CONSENSUS II)
Am J Cardiol, 79 (2), 115-9
PubMed 9193008

Pyorala K, Pedersen TR, Kjekshus J, Faergeman O, Olsson AG, Thorgeirsson G (1997)
Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease - A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)
Diabetes Care, 20 (4), 614-620

Pyŏrälä K, Pedersen TR, Kjekshus J, Faergeman O, Olsson AG, Thorgeirsson G (1997)
Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease. A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S)
Diabetes Care, 20 (4), 614-20
PubMed 9096989

Rodevand O, Bjornerheim R, Kolbjornsen O, Ihlen H, Kjekshus J (1997)
Left ventricular mass assessed by three-dimensional echocardiography using rotational acquisition
Clin Cardiol, 20 (11), 957-62
PubMed 9383590

Sniderman AD, Pedersen T, Kjekshus J (1997)
Putting low-density lipoproteins at center stage in atherogenesis
Am J Cardiol, 79 (1), 64-7
PubMed 9024738

Aaser E, Gullestad L, Tølløfsrud S, Lundberg J, Hall C, Djøseland O, Kjekshus J, Forfang K (1997)
Effect of bolus injection versus continuous infusion of furosemide on diuresis and neurohormonal activation in patients with severe congestive heart failure
Scand J Clin Lab Invest, 57 (4), 361-7
PubMed 9249883

Publications 1996

Gullestad L, Haywood G, Ross H, Bjornerheim R, Geiran O, Kjekshus J, Simonsen S, Fowler M (1996)
Exercise capacity of heart transplant recipients: the importance of chronotropic incompetence
J Heart Lung Transplant, 15 (11), 1075-83
PubMed 8956116

Gullestad L, Myers J, Noddeland H, Bjørnerheim R, Djøseland O, Hall C, Gieran O, Kjekshus J, Simonsen S (1996)
Influence of the exercise protocol on hemodynamic, gas exchange, and neurohumoral responses to exercise in heart transplant recipients
J Heart Lung Transplant, 15 (3), 304-13
PubMed 8777215

Hall C, Stokke O, Kjekshus J (1996)
[ProANF and heart failure in general practice]
Tidsskr Nor Laegeforen, 116 (25), 3048
PubMed 8975436

Jönsson B, Johannesson M, Kjekshus J, Olsson AG, Pedersen TR, Wedel H (1996)
Cost-effectiveness of cholesterol lowering. Results from the Scandinavian Simvastatin Survival Study (4S)
Eur Heart J, 17 (7), 1001-7
PubMed 8809516

Kjekshus J (1996)
[Cardio-reparation--or cardioversion]
Tidsskr Nor Laegeforen, 116 (15), 1774-5
PubMed 8693457

Kjekshus J (1996)
Treating the diabetic patient with coronary disease
Eur Heart J, 17 (9), 1298-301
PubMed 8880010

Kjekshus J, Faergeman O (1996)
[Reduction of cholesterol prevents disease]
Tidsskr Nor Laegeforen, 116 (28), 3319-20
PubMed 9011985

Kjekshus J, Pedersen TR, Tobert JA (1996)
Lipid-lowering therapy for patients with or at risk of coronary artery disease
Curr Opin Cardiol, 11 (4), 418-27
PubMed 8879953

Kjekshus J, Swedberg K (1996)
Treatment of heart failure
J Intern Med, 239 (4), 335-43
PubMed 8774388

Pedersen TR, Berg K, Cook TJ, Faergeman O, Haghfelt T, Kjekshus J, Miettinen T, Musliner TA, Olsson AG, Pyörälä K, Thorgeirsson G, Tobert JA, Wedel H, Wilhelmsen L (1996)
Safety and tolerability of cholesterol lowering with simvastatin during 5 years in the Scandinavian Simvastatin Survival Study
Arch Intern Med, 156 (18), 2085-92
PubMed 8862101

Pedersen TR, Kjekshus J, Berg K, Olsson AG, Wilhelmsen L, Wedel H, Pyörälä K, Miettinen T, Haghfelt T, Faergeman O, Thorgeirsson G, Jönsson B, Schwartz JS (1996)
Cholesterol lowering and the use of healthcare resources. Results of the Scandinavian Simvastatin Survival Study
Circulation, 93 (10), 1796-802
PubMed 8635258

Sirnes PA, Golf S, Myreng Y, Mølstad P, Emanuelsson H, Albertsson P, Brekke M, Mangschau A, Endresen K, Kjekshus J (1996)
Stenting in Chronic Coronary Occlusion (SICCO): a randomized, controlled trial of adding stent implantation after successful angioplasty
J Am Coll Cardiol, 28 (6), 1444-51
PubMed 8917256

Publications 1995

Andreassen AK, Gullestad L, Bjørnerheim R, Forfang K, Kjekshus J (1995)
[Intermittent claudication and beta-blockaders. An unfortunate combination?]
Tidsskr Nor Laegeforen, 115 (6), 725-8
PubMed 7900137

COLLINS R, PETO R, FLATHER M, PARISH S, SLEIGHT P, CONWAY M, PIPILIS A, BAIGENT C, BARNETT D, BOISSEL JP, BUDAJ A, CAIRNS J, CEREMUZYNSKI L, COHEN AF, DEBACKER G, DIAZ R, DIENSTL F, DOVE P, FRANZOSI MG, GENONI M, HALON DA, HEIKKILA J, HENNEKENS C, HORGAN J, HUNT D et al. (1995)
ISIS-4 - A RANDOMIZED FACTORIAL TRIAL ASSESSING EARLY ORAL CAPTOPRIL, ORAL MONONITRATE, AND INTRAVENOUS MAGNESIUM-SULFATE IN 58,050 PATIENTS WITH SUSPECTED ACUTE MYOCARDIAL-INFARCTION
Lancet, 345 (8951), 669-685

Dickstein K, Chang P, Willenheimer R, Haunsø S, Remes J, Hall C, Kjekshus J (1995)
Comparison of the effects of losartan and enalapril on clinical status and exercise performance in patients with moderate or severe chronic heart failure
J Am Coll Cardiol, 26 (2), 438-45
PubMed 7608448

Eriksson SV, Caidahl K, Hall C, Eneroth P, Kjekshus J, Offstad J, Swedberg K (1995)
Atrial natriuretic peptide ANP(1-98) and ANP(99-126) in patients with severe chronic congestive heart failure: relation to echocardiographic measurements. A subgroup analysis from the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
J Card Fail, 1 (2), 109-16
PubMed 9420640

Gullestad L, Simonsen S, Kjekshus J (1995)
[Reduced physical tolerance in patients with heart failure. Mechanisms and therapeutic effects]
Tidsskr Nor Laegeforen, 115 (1), 38-42
PubMed 7846658

Kendall MJ, Lynch KP, Hjalmarson A, Kjekshus J (1995)
Beta-blockers and sudden cardiac death
Ann Intern Med, 123 (5), 358-67
PubMed 7625625

Kjekshus J, Pedersen TR (1995)
Reducing the risk of coronary events: evidence from the Scandinavian Simvastatin Survival Study (4S)
Am J Cardiol, 76 (9), 64C-68C
PubMed 7572690

KJEKSHUS J, PEDERSEN TR (1995)
REDUCING THE RISK OF CORONARY EVENTS - EVIDENCE FROM THE SCANDINAVIAN SIMVASTATIN SURVIVAL STUDY (4S)
Am. J. Cardiol., 76 (9), C64-C68

Myhre ES, Gundersen T, Dickstein K, Hole T, Kjekshus J, Rønnevik P, Smith P, Westheim A (1995)
[Chronic left heart ventricle failure and inotropic stimulation]
Tidsskr Nor Laegeforen, 115 (3), 360-4
PubMed 7855836

PEDERSEN TR, KJEKSHUS J, BERG K, HAGHFELT T, FAERGEMAN O, THORGEIRSSON G, PYORALA K, MIETTINEN T, WILHELMSEN L, OLSSON AG, WEDEL H (1995)
BASE-LINE SERUM-CHOLESTEROL AND TREATMENT EFFECT IN THE SCANDINAVIAN SIMVASTATIN SURVIVAL STUDY (4S)
Lancet, 345 (8960), 1274-1275

Publications 1994

Eriksson SV, Eneroth P, Kjekshus J, Offstad J, Swedberg K (1994)
Neuroendocrine activation in relation to left ventricular function in chronic severe congestive heart failure: a subgroup analysis from the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
Clin Cardiol, 17 (11), 603-6
PubMed 7834934

Eriksson SV, Kjekshus J, Offstad J, Swedberg K (1994)
Patient characteristics in cases of chronic severe heart failure with different degrees of left ventricular systolic dysfunction
Cardiology, 85 (3-4), 137-44
PubMed 7987868

Gullestad L, Midtvedt K, Dolva LO, Norseth J, Kjekshus J (1994)
The magnesium loading test: reference values in healthy subjects
Scand J Clin Lab Invest, 54 (1), 23-31
PubMed 8171268

Gullestad L, Nes M, Rønneberg R, Midtvedt K, Falch D, Kjekshus J (1994)
Magnesium status in healthy free-living elderly Norwegians
J Am Coll Nutr, 13 (1), 45-50
PubMed 8157853

Hall C, Kjekshus J, Eneroth P, Snapinn S (1994)
The plasma concentration of N-terminal proatrial natriuretic factor ANF(1-98) is related to prognosis in severe heart failure
Clin Cardiol, 17 (4), 191-5
PubMed 8187369

Kjekshus J (1994)
[Treatment of heart failure--life and doctrine]
Tidsskr Nor Laegeforen, 114 (21), 2471-2
PubMed 7940445

PEDERSEN TR, KJEKSHUS J, OLSSON AG, BERG K, FAERGEMAN O, HAGHFELT T, MIETTINEN T, PYORALA K, THORGEIRSSON G, WEDEL H, WILHELMSEN L (1994)
SCANDINAVIAN SIMVASTATIN STUDY (4S) - REPLY
Lancet, 344 (8939-4), 1767-1768

Westheim A, Dickstein K, Gundersen T, Hole T, Myhre ES, Rønnevik PK, Smith P, Kjekshus J (1994)
[Chronic heart failure. A management program. Proposal for diagnosis and treatment]
Tidsskr Nor Laegeforen, 114 (12), 1424-7
PubMed 8079230

Publications 1993

Gullestad L, Birkeland K, Mølstad P, Høyer MM, Vanberg P, Kjekshus J (1993)
The effect of magnesium versus verapamil on supraventricular arrhythmias
Clin Cardiol, 16 (5), 429-34
PubMed 8504578

KJEKSHUS J, BERG K, PEDERSEN TR, OLSSON AG, WILHELMSEN L, WEDEL H, PYORALA K, MIETTINEN T, HAGHFELT T, FAERGEMAN O, THORGEIRSSON G, KRISTIANSON K, KRISTOFFERSEN B, GRAN T, LEHTO S, MIETTINEN H, ROMO M, THYGESEN K, HWANG IK, JULIAN DG, LUBSEN J, SMITH WM, FURBERG C, HUTTUNEN J (1993)
DESIGN AND BASE-LINE RESULTS OF THE SCANDINAVIAN SIMVASTATIN SURVIVAL STUDY OF PATIENTS WITH STABLE ANGINA AND OR PREVIOUS MYOCARDIAL-INFARCTION
Am. J. Cardiol., 71 (5), 393-400

KJEKSHUS J, SWEDBERG K (1993)
ACE INHIBITORS AFTER MYOCARDIAL-INFARCTION
N. Engl. J. Med., 328 (13), 968-969

Swedberg K, Kjekshus J (1993)
ACE inhibitors after myocardial infarction
BMJ, 306 (6882), 926-7
PubMed 8490427

Publications 1992

Collins R, Keech A, Peto R, Sleight P, Kjekshus J, Wilhelmsen L, MacMahon S, Shaw J, Simes J, Braunwald E (1992)
Cholesterol and total mortality: need for larger trials
BMJ, 304 (6843), 1689
PubMed 1633527

Gullestad L, Dolva LO, Søyland E, Manger AT, Falch D, Kjekshus J (1992)
Oral magnesium supplementation improves metabolic variables and muscle strength in alcoholics
Alcohol Clin Exp Res, 16 (5), 986-90
PubMed 1443440

Gullestad L, Dolva LO, Waage A, Falch D, Fagerthun H, Kjekshus J (1992)
Magnesium deficiency diagnosed by an intravenous loading test
Scand J Clin Lab Invest, 52 (4), 245-53
PubMed 1439510

Gullestad L, Kjekshus J (1992)
[Sudden cardiac death. Significance of beta blockaders]
Tidsskr Nor Laegeforen, 112 (22), 2843-7
PubMed 1357774

Gullestad L, Kjekshus J (1992)
[Myocardial disease in diabetes mellitus]
Tidsskr Nor Laegeforen, 112 (8), 1016-9
PubMed 1553723

Kjekshus J (1992)
[Treatment of chronic heart failure]
Tidsskr Nor Laegeforen, 112 (17), 2177-8
PubMed 1523647

Kjekshus J, Swedberg K, Snapinn S (1992)
Effects of enalapril on long-term mortality in severe congestive heart failure. CONSENSUS Trial Group
Am J Cardiol, 69 (1), 103-7
PubMed 1729857

Ljungman S, Kjekshus J, Swedberg K (1992)
Renal function in severe congestive heart failure during treatment with enalapril (the Cooperative North Scandinavian Enalapril Survival Study [CONSENSUS] Trial)
Am J Cardiol, 70 (4), 479-87
PubMed 1642186

Swedberg K, Held P, Kjekshus J, Rasmussen K, Rydén L, Wedel H (1992)
Effects of the early administration of enalapril on mortality in patients with acute myocardial infarction. Results of the Cooperative New Scandinavian Enalapril Survival Study II (CONSENSUS II)
N Engl J Med, 327 (10), 678-84
PubMed 1495520

Publications 1991

Gullestad L, Birkeland K, Nordby G, Larsen S, Kjekshus J (1991)
Effects of selective beta 2-adrenoceptor blockade on serum potassium and exercise performance in normal men
Br J Clin Pharmacol, 32 (2), 201-7
PubMed 1681847

Gullestad L, Oystein Dolva L, Birkeland K, Falch D, Fagertun H, Kjekshus J (1991)
Oral versus intravenous magnesium supplementation in patients with magnesium deficiency
Magnes Trace Elem, 10 (1), 11-6
PubMed 1814318

Publications 1990

Eriksson SV, Offstad J, Kjekshus J (1990)
M-mode echocardiography in patients with severe congestive heart failure. A subgroup analysis in the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
Drugs, 39 Suppl 4, 43-8; discussion 53-4
PubMed 2191854

Gilpin EA, Olshen RA, Chatterjee K, Kjekshus J, Moss AJ, Henning H, Engler R, Blacky AR, Dittrich H, Ross J (1990)
Predicting 1-year outcome following acute myocardial infarction: physicians versus computers
Comput Biomed Res, 23 (1), 46-63
PubMed 2306934

Hjalmarson A, Gilpin EA, Kjekshus J, Schieman G, Nicod P, Henning H, Ross J (1990)
Influence of heart rate on mortality after acute myocardial infarction
Am J Cardiol, 65 (9), 547-53
PubMed 1968702

Kjekshus J (1990)
Arrhythmias and mortality in congestive heart failure
Am J Cardiol, 65 (19), 42I-48I
PubMed 2159694

Kjekshus J, Gilpin E, Cali G, Blackey AR, Henning H, Ross J (1990)
Diabetic patients and beta-blockers after acute myocardial infarction
Eur Heart J, 11 (1), 43-50
PubMed 1968386

Swedberg K, Eneroth P, Kjekshus J, Snapinn S (1990)
Effects of enalapril and neuroendocrine activation on prognosis in severe congestive heart failure (follow-up of the CONSENSUS trial). CONSENSUS Trial Study Group
Am J Cardiol, 66 (11), 40D-44D; discussion 44D-45D
PubMed 2220604

Swedberg K, Eneroth P, Kjekshus J, Wilhelmsen L (1990)
Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group
Circulation, 82 (5), 1730-6
PubMed 2225374

Swedberg K, Kjekshus J (1990)
Effect of enalapril on mortality in congestive heart failure. Follow-up survival data from the CONSENSUS trial
Drugs, 39 Suppl 4, 49-52; discussion 53-4
PubMed 2191855

Publications 1989

Gullestad L, Dolva LO, Kjeldsen SE, Eide I, Kjekshus J (1989)
Effect of beta-adrenergic blockade on hormonal responses during continuous and intermittent exercise
Cardiovasc Drugs Ther, 3 (1), 63-71
PubMed 2577280

Gullestad L, Dolva LO, Nordby G, Skaaraas K, Larsen S, Kjekshus J (1989)
The importance of potassium and lactate for maximal exercise performance during beta blockade
Scand J Clin Lab Invest, 49 (6), 521-8
PubMed 2574496

Gullestad L, Dolva LO, Søyland E, Kjekshus J (1989)
[Beta blockaders and physical performance. Limiting factors]
Tidsskr Nor Laegeforen, 109 (25), 2544-7
PubMed 2573167

Gullestad L, Dolva LO, Aase O, Kjekshus J (1989)
Interaction of naloxone and timolol on maximal exercise capacity and the subjective perception of fatigue
Int J Sports Med, 10 (4), 259-63
PubMed 2606592

Kjekshus J, Swedberg K (1989)
Enalapril for congestive heart failure
Am J Cardiol, 63 (8), 26D-32D
PubMed 2537563

Publications 1988

Bjartveit K, Blomhoff JP, Drevon CA, Gjone E, Hjermann I, Holm HA, Kjekshus J, Levorsen A, Norum KR, Nylenna M (1988)
[Treatment of hypercholesterolemia in adults. An action plan]
Tidsskr Nor Laegeforen, 108 (27), 2285-8
PubMed 3206437

Gullestad L, Dolva LO, Søyland E, Kjekshus J (1988)
Difference between beta-1-selective and non-selective beta-blockade during continuous and intermittent exercise
Clin Physiol, 8 (5), 487-99
PubMed 3191663

Hall C, Mørkrid L, Kjekshus J (1988)
Redistribution of peripheral blood flow during acute left ventricular failure in the dog
Scand J Clin Lab Invest, 48 (8), 785-94
PubMed 3238323

Kjekshus J, Swedberg K (1988)
Tolerability of enalapril in congestive heart failure
Am J Cardiol, 62 (2), 67A-72A
PubMed 2839020

Kjekshus J, Vaagenes P (1988)
Cerebrospinal fluid creatine kinase isoenzyme BB levels do not predict the clinical outcome in patients unconscious following cardiac resuscitation
Clin Cardiol, 11 (5), 286, 364
PubMed 3383465

Swedberg K, Kjekshus J (1988)
Effects of enalapril on mortality in severe congestive heart failure: results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
Am J Cardiol, 62 (2), 60A-66A
PubMed 2839019

Publications 1987

Gullestad L, Dolva LO, Kjeldsen SE, Eide I, Kjekshus J (1987)
The effects of naloxone and timolol on plasma catecholamine levels during short-term dynamic exercise
Scand J Clin Lab Invest, 47 (8), 847-51
PubMed 2893446

Gullestad L, Søyland E, Dolva LO, Kjekshus J (1987)
[Angiotensin-converting enzyme inhibitors in heart failure]
Tidsskr Nor Laegeforen, 107 (25), 2112-6
PubMed 2823410

Gullestad L, Søyland E, Kjekshus J, Aase O, Bjørnstad P (1987)
[Magnesium deficiency. Diagnosis and occurrence of different disease conditions]
Tidsskr Nor Laegeforen, 107 (22), 1751-4
PubMed 3660356

Hall C, Mørkrid L, Kjekshus J (1987)
Effect of ACE-inhibition on tissue blood flow during acute left ventricular failure in the dog
Res Exp Med (Berl), 187 (1), 59-70
PubMed 3033782

Kjekshus J (1987)
Heart rate reduction--a mechanism of benefit?
Eur Heart J, 8 Suppl L, 115-22
PubMed 2897914

Kjekshus J (1987)
Nitrates in acute myocardial infarction
Drugs, 33 Suppl 4, 140-6
PubMed 3304958

Vaagenes P, Kjekshus J, Sivertsen E, Semb G (1987)
Temporal pattern of enzyme changes in cerebrospinal fluid in patients with neurologic complications after open heart surgery
Crit Care Med, 15 (8), 726-31
PubMed 3608528

WESTHEIM A, GRENDAHL H, KJEKSHUS J, SIVERTSSEN E, REFSUM HE (1987)
HEMODYNAMICS DURING REPEATED EXERCISE TESTS WITH SPECIAL REFERENCE TO THE WARM-UP PHENOMENON IN PATIENTS WITH ANGINA-PECTORIS
Clin. Physiol., 7 (2), 83-94

Westheim A, Grendahl H, Kjekshus J, Sivertssen E, Refsum HE (1987)
Haemodynamics during repeated exercise tests with special reference to the 'warm-up' phenomenon in patients with angina pectoris
Clin Physiol, 7 (2), 83-94
PubMed 3568584

Publications 1986

Gullestad L, Søyland E, Kjekshus J (1986)
[Magnesium and cardiovascular diseases]
Tidsskr Nor Laegeforen, 106 (7), 554-7
PubMed 3961781

Publications 1985

Grendahl H, Semb G, Kjekshus J (1985)
[Automatic implantable defibrillator. A method for the treatment of life-threatening arrhythmias]
Tidsskr Nor Laegeforen, 105 (19-21), 1310-1
PubMed 4012743

Gundersen T, Kjekshus J (1985)
The importance of pre- and postinfarction angina on timolol-related reduction in mortality and reinfarction
Clin Cardiol, 8 (2), 87-92
PubMed 3882290

Gundersen T, Kjekshus J (1985)
Timolol-related reduction in mortality and reinfarction in diabetic patients surviving acute myocardial infarction
Horm Metab Res Suppl, 15, 58-60
PubMed 3908282

Gundersen T, Kjekshus J, Stokke O, Pedersen T (1985)
Timolol maleate and HDL cholesterol after myocardial infarction
Eur Heart J, 6 (10), 840-4
PubMed 3908104

Nordrehaug JE, Johannessen KA, von der Lippe G, Sederholm M, Grøttum P, Kjekshus J (1985)
Effect of timolol on changes in serum potassium concentration during acute myocardial infarction
Br Heart J, 53 (4), 388-93
PubMed 3885979

Sederholm M, Grøttum P, Kjekshus J, Erhardt L (1985)
Course of chest pain and its relation to CK release and ST/QRS vector changes in patients with acute myocardial infarction randomized to treatment with intravenous timolol or placebo
Am Heart J, 110 (3), 521-8
PubMed 3898795

Publications 1984

Bjertnaes L, Hauge A, Kjekshus J, Søyland E (1984)
Cardiovascular responses to face immersion and apnea during steady state muscle exercise. A heart catheterization study on humans
Acta Physiol Scand, 120 (4), 605-12
PubMed 6485832

Dickstein K, Søyland E, Gundersen T, Abrahamsen AM, Kjekshus J (1984)
Acute and chronic hemodynamic effects of enalapril (MK-421) in congestive heart failure
Int J Cardiol, 6 (4), 445-58
PubMed 6092286

Ellingsen O, Kjekshus J (1984)
[Prazosin in exercise-induced angina pectoris. An open study of work capacity after a single dose of prazosin, isosorbide dinitrate, atenolol and nifedipine]
Tidsskr Nor Laegeforen, 104 (9), 657-60
PubMed 6729795

Hall C, Mørkrid L, Kjekshus J (1984)
Effect of ACE-Inhibition on regional blood flow during acute left ventricular failure in the dog. Preliminary report
Scand J Urol Nephrol Suppl, 79, 121-4
PubMed 6089310

Hall C, Mørkrid L, Kjekshus J (1984)
Effect of Ace-Inhibition on Regional Blood Flow During Acute Left Ventricular Failure in the Dog
Scand J Urol Nephrol, 18 (sup79), 121-124
PubMed 27786020

Kjekshus J (1984)
ACE Inhibitors in heart failure
Scand J Urol Nephrol Suppl, 79, 115-20
PubMed 6089309

Kjekshus J (1984)
Ace Inhibitors in Heart Failure
Scand J Urol Nephrol, 18 (sup79), 115-120
PubMed 27786016

KJEKSHUS J, BATHEN J, ORNING OM, STORSTEIN L (1984)
A DOUBLE-BLIND, CROSSOVER COMPARISON OF FLECAINIDE ACETATE AND DISOPYRAMIDE PHOSPHATE IN THE TREATMENT OF VENTRICULAR PREMATURE COMPLEXES
Am. J. Cardiol., 53 (5), B72-B78

Kjekshus J, Bathen J, Orning OM, Storstein L (1984)
A double-blind, crossover comparison of flecainide acetate and disopyramide phosphate in the treatment of ventricular premature complexes
Am J Cardiol, 53 (5), 72B-78B
PubMed 6421140

Publications 1983

Bøhmer T, Kjekshus J, Vaagenes P (1983)
Biochemical indices of cerebral ischemic injury
Scand J Clin Lab Invest, 43 (3), 261-5
PubMed 6622972

Gundersen T, Kjekshus J (1983)
Timolol treatment after myocardial infarction in diabetic patients
Diabetes Care, 6 (3), 285-90
PubMed 6347581

Sederholm M, Grøttum P, Erhardt L, Kjekshus J (1983)
Quantitative assessment of myocardial ischemia and necrosis by continuous vectorcardiography and measurement of creatine kinase release in patients
Circulation, 68 (5), 1006-12
PubMed 6616784

Publications 1982

Gundersen T, Abrahamsen AM, Kjekshus J, Rønnevik PK (1982)
Timolol-related reduction in mortality and reinfarction in patients ages 65-75 years surviving acute myocardial infarction. Prepared for the Norwegian Multicentre Study Group
Circulation, 66 (6), 1179-84
PubMed 6128084

Thaulow E, Dale J, Kjekshus J, Simonsen S, Hovig T, Solum NO (1982)
Pacing induced angina and platelet reactivity
Scand J Clin Lab Invest, 42 (8), 607-11
PubMed 7167726

Thaulow E, Ihlen H, Kjekshus J, Forfang K, Storstein O (1982)
Effects of red rest and prazosin in congestive heart failure
Acta Med Scand, 212 (3), 131-6
PubMed 7148503

THAULOW E, IHLEN H, KJEKSHUS J, FORFANG K, STORSTEIN O (1982)
EFFECTS OF BED REST AND PRAZOSIN IN CONGESTIVE HEART-FAILURE
Acta Med. Scand., 212 (3), 131-136

Publications 1981

Ihlen H, Thaulow E, Kjekshus J, Forfang K (1981)
Loss of prazosin effect in severe chronic CHF
Acta Med Scand Suppl, 652, 149-54
PubMed 6949461

IHLEN H, THAULOW E, KJEKSHUS J, FORFANG K (1981)
LOSS OF PRAZOSIN EFFECT IN SEVERE CHRONIC CHF
Acta Med. Scand. (652), 149-154

THAULOW E, KJEKSHUS J, ERIKSSEN J (1981)
EFFECT OF TIMOLOL ON PLATELET-AGGREGATION IN CORONARY HEART-DISEASE
Acta Med. Scand. (651), 101-109

Thaulow E, Kjekshus J, Erikssen J (1981)
Effect of timolol on platelet aggregation in coronary heart disease
Acta Med Scand Suppl, 651, 101-9
PubMed 7034470

von der Lippe G, Lund-Johansen P, Kjekshus J (1981)
Effect of timolol on late ventricular arrhythmias after acute myocardial infarction
Acta Med Scand Suppl, 651, 253-63
PubMed 6948502

Publications 1980

Vaagenes P, Kjekshus J, Torvik A (1980)
The relationship between cerebrospinal fluid creatine kinase and morphologic changes in the brain after transient cardiac arrest
Circulation, 61 (6), 1194-9
PubMed 7371132

Publications 1979

Grendahl H, Kjekshus J, Soyland E, Sivertssen E (1979)
Escape rhythm in complete A-V block. The recovery phase after overdrive suppression from artificial ventricular suppression from artificial ventricular pacing
Pacing Clin Electrophysiol, 2 (4), 455-61
PubMed 95314

Publications 1978

Grendahl H, Miller M, Kjekshus J (1978)
Overdrive suppression of implanted pacemakers in patients with AV block
Br Heart J, 40 (2), 106-13
PubMed 637960

Westheim AS, Christensen CC, Kjekshus J (1978)
Effect of penbutolol (Hoe 893 d) and practolol on exercise-induced angina pectoris 2 and 24 hours after a signle oral dose
Eur J Clin Pharmacol, 13 (3), 157-62
PubMed 27370

Publications 1972

Kjekshus J, Mjos OD (1972)
Effect of increased afterload on the inotropic state and uptake of free fatty acids in the intact dog heart
Acta Physiol Scand, 84 (3), 415-27
PubMed 5019038

Publications 1971

Kjekshus J, Noer G (1971)
[Determining the blood flow through the myocardium in patients]
Nord Med, 86 (34), 1014
PubMed 5099376

Mjös OD, Kjekshus J (1971)
Increased local metabolic rate by free fatty acids in the intact dog heart
Scand J Clin Lab Invest, 28 (4), 389-93
PubMed 5157041

Publications 1970

Bugge-Asperheim B, Kjekshus J (1970)
Left ventricular pressure and maximum rate of pressure rise as determinants of myocardial oxygen consumption during hemorrhagic hypotension in dogs
Acta Physiol Scand, 78 (2), 174-83
PubMed 4318564

Publications 1969

Kiil F, Kjekshus J, Löyning E (1969)
Renal autoregulation during infusion of noradrenaline, angiotensin and acetylcholine
Acta Physiol Scand, 76 (1), 10-23
PubMed 4309891

Kiil F, Kjekshus J, Löyning E (1969)
Role of autoregulation in maintaining glomerular filtration rate at large urine flow
Acta Physiol Scand, 76 (1), 24-39
PubMed 5823389

Kjekshus J, Aukland K, Kiil F (1969)
Oxygen cost of sodium reabsorption in proximal and distal parts of the nephron
Scand J Clin Lab Invest, 23 (4), 307-16
PubMed 4315557

Kjekshus J, Loyning E, Kiil F (1969)
Mechanisms in the maintenance of glomerular filttion rate during high urine flow
Acta Physiol Scand, 76 (1), 19A-20A
PubMed 5823377

Publications 1968

Bugge-Asperheim B, Kjekshus J (1968)
Effects of prolonged hypotension on myocardial function in dogs
Scand J Clin Lab Invest, 21 (2), 145-56
PubMed 5706638

Publications 1967

Aukland K, Kiil F, Kjekshus J (1967)
Relationship between ventricular pressures and right and left myocardial blood flow
Acta Physiol Scand, 70 (1), 116-26
PubMed 6035840

Aukland K, Kiil F, Kjekshus J, Semb G (1967)
Local myocardial blood flow measured by hydrogen polarography; distribution and effect of hypoxia
Acta Physiol Scand, 70 (1), 99-111
PubMed 6035846

Publications 1966

Aukland K, Kjekshus J (1966)
Tubular salt and water transport in hydrated dogs studied with push-flow technique
Am J Physiol, 210 (5), 971-9
PubMed 5947274