Kirsten Muri Boberg
Position: Professor, Head of Section, MD, PhD
Phone: +47 23 07 24 68
Email:
 

Author network for Kirsten Muri Boberg by COREMINE medical


Publications 2017

Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
Gut (in press)
PubMed 28779025

de Vries EM, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
Liver Int (in press)
PubMed 28267887

Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
J Hepatol, 66 (6), 1214-1222
PubMed 28161472

Weismüller TJ, Trivedi PJ, Bergquist A, Imam M, Lenzen H, Ponsioen CY, Holm K, Gotthardt D, Färkkilä MA, Marschall HU, Thorburn D, Weersma RK, Fevery J, Mueller T, Chazouillères O, Schulze K, Lazaridis KN, Almer S, Pereira SP, Levy C, Mason A, Naess S, Bowlus CL, Floreani A, Halilbasic E et al. (2017)
Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis
Gastroenterology, 152 (8), 1975-1984.e8
PubMed 28274849

Publications 2016

Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D (2016)
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Nat Rev Gastroenterol Hepatol, 13 (5), 261-80
PubMed 27095655

Bernuzzi F, Marabita F, Lleo A, Carbone M, Mirolo M, Marzioni M, Alpini G, Alvaro D, Boberg KM, Locati M, Torzilli G, Rimassa L, Piscaglia F, He XS, Bowlus CL, Yang GX, Gershwin ME, Invernizzi P (2016)
Serum microRNAs as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma
Clin Exp Immunol, 185 (1), 61-71
PubMed 26864161

Henriksen EK, Jørgensen KK, Kaveh F, Holm K, Hamm D, Olweus J, Melum E, Chung BK, Eide TJ, Lundin KE, Boberg KM, Karlsen TH, Hirschfield GM, Liaskou E (2016)
Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
J Hepatol, 66 (1), 116-122
PubMed 27647428

Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg Ø, Karlsen TH (2016)
Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
Liver Int, 37 (3), 458-465
PubMed 27558072

Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F et al. (2016)
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
Nat Genet, 49 (2), 269-273
PubMed 27992413

Kummen M, Vesterhus M, Trøseid M, Moum B, Svardal A, Boberg KM, Aukrust P, Karlsen TH, Berge RK, Hov JR (2016)
Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
United European Gastroenterol J, 5 (4), 532-541
PubMed 28588885

Zenouzi R, Weismüller TJ, Jørgensen KK, Bubenheim M, Lenzen H, Hübener P, Schulze K, Weiler-Normann C, Sebode M, Ehlken H, Pannicke N, Hartl J, Peiseler M, Hübener S, Karlsen TH, Boberg KM, Manns MP, Lohse AW, Schramm C (2016)
No Evidence That Azathioprine Increases Risk of Cholangiocarcinoma in Patients With Primary Sclerosing Cholangitis
Clin Gastroenterol Hepatol, 14 (12), 1806-1812
PubMed 27521513

Publications 2015

Andersen IM, Fosby B, Boberg KM, Clausen OP, Jebsen P, Melum E, Line PD, Foss A, Schrumpf E, Karlsen TH (2015)
Indications and Outcomes in Liver Transplantation in Patients With Primary Sclerosing Cholangitis in Norway
Transplant Direct, 1 (9), e39
PubMed 27500239

Andresen K, Boberg KM, Vedeld HM, Honne H, Jebsen P, Hektoen M, Wadsworth CA, Clausen OP, Lundin KE, Paulsen V, Foss A, Mathisen Ø, Aabakken L, Schrumpf E, Lothe RA, Lind GE (2015)
Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
Hepatology, 61 (5), 1651-9
PubMed 25644509

Berntsen NL, Klingenberg O, Juran BD, Benito de Valle M, Lindkvist B, Lazaridis KN, Boberg KM, Karlsen TH, Hov JR (2015)
Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis
Gastroenterology, 148 (5), 924-927.e2
PubMed 25655558

Folseraas T, Boberg KM (2015)
Cancer Risk and Surveillance in Primary Sclerosing Cholangitis
Clin Liver Dis, 20 (1), 79-98
PubMed 26593292

Fosby B, Melum E, Bjøro K, Bennet W, Rasmussen A, Andersen IM, Castedal M, Olausson M, Wibeck C, Gotlieb M, Gjertsen H, Toivonen L, Foss S, Makisalo H, Nordin A, Sanengen T, Bergquist A, Larsson ME, Soderdahl G, Nowak G, Boberg KM, Isoniemi H, Keiding S, Foss A, Line PD et al. (2015)
Liver transplantation in the Nordic countries - An intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982-2013
Scand J Gastroenterol, 50 (6), 797-808
PubMed 25959101

Harbord M, Annese V, Vavricka SR, Allez M, Barreiro-de Acosta M, Boberg KM, Burisch J, De Vos M, De Vries AM, Dick AD, Juillerat P, Karlsen TH, Koutroubakis I, Lakatos PL, Orchard T, Papay P, Raine T, Reinshagen M, Thaci D, Tilg H, Carbonnel F, European Crohn’s and Colitis Organisation (2015)
The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease
J Crohns Colitis, 10 (3), 239-54
PubMed 26614685

Schrumpf E, Boberg KM, Karlsen TH (2015)
Primary sclerosing cholangitis - the Norwegian experience
Scand J Gastroenterol, 50 (6), 781-96
PubMed 25866138

Thorsen T, Dahlgren US, Aandahl EM, Grzyb K, Karlsen TH, Boberg KM, Rydberg L, Naper C, Foss A, Bennet W (2015)
Liver transplantation with deceased ABO-incompatible donors is life-saving but associated with increased risk of rejection and post-transplant complications
Transpl Int, 28 (7), 800-12
PubMed 25736519

Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
Hepatology, 62 (1), 188-97
PubMed 25833813

Åberg F, Gissler M, Karlsen TH, Ericzon BG, Foss A, Rasmussen A, Bennet W, Olausson M, Line PD, Nordin A, Bergquist A, Boberg KM, Castedal M, Pedersen CR, Isoniemi H (2015)
Differences in long-term survival among liver transplant recipients and the general population: a population-based Nordic study
Hepatology, 61 (2), 668-77
PubMed 25266201

Publications 2014

Fosby B, Næss S, Hov JR, Traherne J, Boberg KM, Trowsdale J, Foss A, Line PD, Franke A, Melum E, Scott H, Karlsen TH (2014)
HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation
World J Gastroenterol, 20 (14), 3986-4000
PubMed 24744588

Naess S, Björnsson E, Anmarkrud JA, Al Mamari S, Juran BD, Lazaridis KN, Chapman R, Bergquist A, Melum E, Marsh SG, Schrumpf E, Lie BA, Boberg KM, Karlsen TH, Hov JR (2014)
Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease
Liver Int, 34 (10), 1488-95
PubMed 24517468

Næss S, Lie BA, Melum E, Olsson M, Hov JR, Croucher PJ, Hampe J, Thorsby E, Bergquist A, Traherne JA, Schrumpf E, Boberg KM, Schreiber S, Franke A, Karlsen TH (2014)
Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population
PLoS One, 9 (12), e114486
PubMed 25521205

Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2014)
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
Int J Cancer, 136 (4), 844-53
PubMed 24948044

Publications 2013

Andersen IM, Tengesdal G, Lie BA, Boberg KM, Karlsen TH, Hov JR (2013)
Effects of coffee consumption, smoking, and hormones on risk for primary sclerosing cholangitis
Clin Gastroenterol Hepatol, 12 (6), 1019-28
PubMed 24076415

Block M, Jørgensen KK, Oresland T, Lindholm E, Grzyb K, Cvancarova M, Vatn MH, Boberg KM, Börjesson L (2013)
Colectomy for patients with ulcerative colitis and primary sclerosing cholangitis - what next?
J Crohns Colitis, 8 (5), 421-30
PubMed 24239402

Boberg KM, Wisløff T, Kjøllesdal KS, Støvring H, Kristiansen IS (2013)
Cost and health consequences of treatment of primary biliary cirrhosis with ursodeoxycholic acid
Aliment Pharmacol Ther, 38 (7), 794-803
PubMed 23915021

Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
Hepatology, 58 (3), 1074-83
PubMed 22821403

Hagness M, Foss A, Line PD, Scholz T, Jørgensen PF, Fosby B, Boberg KM, Mathisen O, Gladhaug IP, Egge TS, Solberg S, Hausken J, Dueland S (2013)
Liver transplantation for nonresectable liver metastases from colorectal cancer
Ann Surg, 257 (5), 800-6
PubMed 23360920

Jørgensen KK, Lindström L, Cvancarova M, Karlsen TH, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2013)
Immunosuppression after liver transplantation for primary sclerosing cholangitis influences activity of inflammatory bowel disease
Clin Gastroenterol Hepatol, 11 (5), 517-23
PubMed 23333218

Karlsen TH, Boberg KM (2013)
Update on primary sclerosing cholangitis
J Hepatol, 59 (3), 571-82
PubMed 23603668

Karlsen TH, Vesterhus M, Boberg KM (2013)
Review article: controversies in the management of primary biliary cirrhosis and primary sclerosing cholangitis
Aliment Pharmacol Ther, 39 (3), 282-301
PubMed 24372568

Kummen M, Schrumpf E, Boberg KM (2013)
Liver abnormalities in bowel diseases
Best Pract Res Clin Gastroenterol, 27 (4), 531-42
PubMed 24090940

Lindström L, Hultcrantz R, Boberg KM, Friis-Liby I, Bergquist A (2013)
Association between reduced levels of alkaline phosphatase and survival times of patients with primary sclerosing cholangitis
Clin Gastroenterol Hepatol, 11 (7), 841-6
PubMed 23353641

Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Srivastava B, Dalekos G, Nöthen MM, Herms S et al. (2013)
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Nat Genet, 45 (6), 670-5
PubMed 23603763

Wannhoff A, Hov JR, Folseraas T, Rupp C, Friedrich K, Anmarkrud JA, Weiss KH, Sauer P, Schirmacher P, Boberg KM, Stremmel W, Karlsen TH, Gotthardt DN (2013)
FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis
J Hepatol, 59 (6), 1278-84
PubMed 23958938

Publications 2012

Andresen K, Boberg KM, Vedeld HM, Honne H, Hektoen M, Wadsworth CA, Clausen OP, Karlsen TH, Foss A, Mathisen O, Schrumpf E, Lothe RA, Lind GE (2012)
Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
Epigenetics, 7 (11), 1249-57
PubMed 22983262

Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
J Hepatol, 57 (2), 366-75
PubMed 22521342

Haugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Waelgaard L, Pischke SE, Mollnes TE, Inge Tønnessen T (2012)
Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts
Liver Transpl, 18 (12), 1421-9
PubMed 22767413

Håugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2012)
Early bedside detection of ischemia and rejection in liver transplants by microdialysis
Liver Transpl, 18 (7), 839-49
PubMed 22407878

Jørgensen KK, Lindström L, Cvancarova M, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2012)
Colorectal neoplasia in patients with primary sclerosing cholangitis undergoing liver transplantation: a Nordic multicenter study
Scand J Gastroenterol, 47 (8-9), 1021-9
PubMed 22577871

Lindström L, Boberg KM, Wikman O, Friis-Liby I, Hultcrantz R, Prytz H, Sandberg-Gertzén H, Sangfelt P, Rydning A, Folvik G, Gangsøy-Kristiansen M, Danielsson A, Bergquist A (2012)
High dose ursodeoxycholic acid in primary sclerosing cholangitis does not prevent colorectal neoplasia
Aliment Pharmacol Ther, 35 (4), 451-7
PubMed 22221173

Publications 2011

Boberg KM, Lind GE (2011)
Primary sclerosing cholangitis and malignancy
Best Pract Res Clin Gastroenterol, 25 (6), 753-64
PubMed 22117640

Hov JR, Kosmoliaptsis V, Traherne JA, Olsson M, Boberg KM, Bergquist A, Schrumpf E, Bradley JA, Taylor CJ, Lie BA, Trowsdale J, Karlsen TH (2011)
Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis
Hepatology, 53 (6), 1967-76
PubMed 21413052

Janse M, Lamberts LE, Franke L, Raychaudhuri S, Ellinghaus E, Muri Boberg K, Melum E, Folseraas T, Schrumpf E, Bergquist A, Björnsson E, Fu J, Jan Westra H, Groen HJ, Fehrmann RS, Smolonska J, van den Berg LH, Ophoff RA, Porte RJ, Weismüller TJ, Wedemeyer J, Schramm C, Sterneck M, Günther R, Braun F et al. (2011)
Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
Hepatology, 53 (6), 1977-85
PubMed 21425313

Jørgensen KK, Grzyb K, Lundin KE, Clausen OP, Aamodt G, Schrumpf E, Vatn MH, Boberg KM (2011)
Inflammatory bowel disease in patients with primary sclerosing cholangitis: clinical characterization in liver transplanted and nontransplanted patients
Inflamm Bowel Dis, 18 (3), 536-45
PubMed 21456044

Naalsund A, Lund MB, Mynarek G, Aakhus S, Boberg KM, Nordøy I (2011)
[A man in his 60s with severe respiratory failure]
Tidsskr Nor Laegeforen, 131 (17), 1654-7
PubMed 21901039

Wiencke K, Boberg KM (2011)
Current consensus on the management of primary sclerosing cholangitis
Clin Res Hepatol Gastroenterol, 35 (12), 786-91
PubMed 21963085

Publications 2010

Boberg KM, Chapman RW, Hirschfield GM, Lohse AW, Manns MP, Schrumpf E, International Autoimmune Hepatitis Group (2010)
Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue
J Hepatol, 54 (2), 374-85
PubMed 21067838

Chapman R, Fevery J, Kalloo A, Nagorney DM, Boberg KM, Shneider B, Gores GJ, American Association for the Study of Liver Diseases (2010)
Diagnosis and management of primary sclerosing cholangitis
Hepatology, 51 (2), 660-78
PubMed 20101749

Dolgos S, Hartmann A, Isaksen GA, Simonsen S, Bjørtuft Ø, Boberg KM, Bollerslev J (2010)
Osteoporosis is a prevalent finding in patients with solid organ failure awaiting transplantation - a population based study
Clin Transplant, 24 (5), E145-52
PubMed 20236290

Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH et al. (2010)
Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
PLoS One, 5 (8), e12403
PubMed 20811628

Karlsen TH, Schrumpf E, Boberg KM (2010)
Update on primary sclerosing cholangitis
Dig Liver Dis, 42 (6), 390-400
PubMed 20172772

Karlsen TH, Schrumpf E, Boberg KM (2010)
Primary sclerosing cholangitis
Best Pract Res Clin Gastroenterol, 24 (5), 655-66
PubMed 20955968

Melum E, Franke A, Schramm C, Weismüller TJ, Gotthardt DN, Offner FA, Juran BD, Laerdahl JK, Labi V, Björnsson E, Weersma RK, Henckaerts L, Teufel A, Rust C, Ellinghaus E, Balschun T, Boberg KM, Ellinghaus D, Bergquist A, Sauer P, Ryu E, Hov JR, Wedemeyer J, Lindkvist B, Wittig M et al. (2010)
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
Nat Genet, 43 (1), 17-9
PubMed 21151127

Ponsioen CY, Reitsma JB, Boberg KM, Aabakken L, Rauws EA, Schrumpf E (2010)
Validation of a cholangiographic prognostic model in primary sclerosing cholangitis
Endoscopy, 42 (9), 742-7
PubMed 20623444

Publications 2009

European Association for the Study of the Liver (2009)
EASL Clinical Practice Guidelines: management of cholestatic liver diseases
J Hepatol, 51 (2), 237-67
PubMed 19501929

Forsbring M, Vik ES, Dalhus B, Karlsen TH, Bergquist A, Schrumpf E, Bjørås M, Boberg KM, Alseth I (2009)
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
Carcinogenesis, 30 (7), 1147-54
PubMed 19443904

Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P et al. (2009)
Genome-wide association analysis in primary sclerosing cholangitis
Gastroenterology, 138 (3), 1102-11
PubMed 19944697

Scholz T, Karlsen TH, Sanengen T, Schrumpf E, Line PD, Boberg KM, Jörgensen PF, Fosby B, Bentdal O, Ostensen AB, Osnes S, Riddervold F, Haugaa H, Hausken J, Bergmann JB, Foss S, Björo K, Foss A, Levertransplantasjonsgruppen ved Oslo universitetssykehus, Rikshospitalet (2009)
[Liver transplantation in Norway through 25 years]
Tidsskr Nor Laegeforen, 129 (24), 2587-92
PubMed 20029553

Yu X, Wieczorek S, Franke A, Yin H, Pierer M, Sina C, Karlsen TH, Boberg KM, Bergquist A, Kunz M, Witte T, Gross WL, Epplen JT, Alarcón-Riquelme ME, Schreiber S, Ibrahim SM (2009)
Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases
Genes Immun, 10 (6), 601-5
PubMed 19387457

Publications 2008

Björnsson E, Olsson R, Bergquist A, Lindgren S, Braden B, Chapman RW, Boberg KM, Angulo P (2008)
The natural history of small-duct primary sclerosing cholangitis
Gastroenterology, 134 (4), 975-80
PubMed 18395078

Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Bianchi FB, Shibata M, Schramm C, Eisenmann de Torres B, Galle PR, McFarlane I, Dienes HP, Lohse AW, International Autoimmune Hepatitis Group (2008)
Simplified criteria for the diagnosis of autoimmune hepatitis
Hepatology, 48 (1), 169-76
PubMed 18537184

Hov JR, Boberg KM, Karlsen TH (2008)
Autoantibodies in primary sclerosing cholangitis
World J Gastroenterol, 14 (24), 3781-91
PubMed 18609700

Karlsen TH, Schrumpf E, Boberg KM (2008)
Gallbladder polyps in primary sclerosing cholangitis: not so benign
Curr Opin Gastroenterol, 24 (3), 395-9
PubMed 18408471

Melum E, Karlsen TH, Bergquist A, Schrumpf E, Boberg KM (2008)
An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitis
Am J Gastroenterol, 103 (4), 1045; author reply 1045-6
PubMed 18397431

Melum E, Karlsen TH, Schrumpf E, Bergquist A, Thorsby E, Boberg KM, Lie BA (2008)
Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms
Hepatology, 47 (1), 90-6
PubMed 18023027

Publications 2007

Eike MC, Nordang GB, Karlsen TH, Boberg KM, Vatn MH, IBSEN study group, Dahl-Jørgensen K, Rønningen KS, Joner G, Flatø B, Bergquist A, Thorsby E, Førre O, Kvien TK, Undlien DE, Lie BA (2007)
The FCRL3 -169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases
Ann Rheum Dis, 67 (9), 1287-91
PubMed 18065500

Karlsen TH, Boberg KM, Olsson M, Sun JY, Senitzer D, Bergquist A, Schrumpf E, Thorsby E, Lie BA (2007)
Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitis
J Hepatol, 46 (5), 899-906
PubMed 17383044

Karlsen TH, Boberg KM, Vatn M, Bergquist A, Hampe J, Schrumpf E, Thorsby E, Schreiber S, Lie BA, IBSEN Study Group (2007)
Different HLA class II associations in ulcerative colitis patients with and without primary sclerosing cholangitis
Genes Immun, 8 (3), 275-8
PubMed 17301827

Karlsen TH, Schrumpf E, Boberg KM (2007)
Genetic epidemiology of primary sclerosing cholangitis
World J Gastroenterol, 13 (41), 5421-31
PubMed 17907284

Wiencke K, Karlsen TH, Boberg KM, Thorsby E, Schrumpf E, Lie BA, Spurkland A (2007)
Primary sclerosing cholangitis is associated with extended HLA-DR3 and HLA-DR6 haplotypes
Tissue Antigens, 69 (2), 161-9
PubMed 17257319

Publications 2006

Berstad AE, Aabakken L, Smith HJ, Aasen S, Boberg KM, Schrumpf E (2006)
Diagnostic accuracy of magnetic resonance and endoscopic retrograde cholangiography in primary sclerosing cholangitis
Clin Gastroenterol Hepatol, 4 (4), 514-20
PubMed 16616358

Boberg KM, Foss A, Midtvedt K, Schrumpf E (2006)
ABO-incompatible deceased donor liver transplantation with the use of antigen-specific immunoadsorption and anti-CD20 monoclonal antibody
Clin Transplant, 20 (2), 265-8
PubMed 16640538

Boberg KM, Jebsen P, Clausen OP, Foss A, Aabakken L, Schrumpf E (2006)
Diagnostic benefit of biliary brush cytology in cholangiocarcinoma in primary sclerosing cholangitis
J Hepatol, 45 (4), 568-74
PubMed 16879890

Bowlus CL, Karlsen TH, Broomé U, Thorsby E, Vatn M, Schrumpf E, Lie BA, Boberg KM (2006)
Analysis of MAdCAM-1 and ICAM-1 polymorphisms in 365 Scandinavian patients with primary sclerosing cholangitis
J Hepatol, 45 (5), 704-10
PubMed 16750586

Karlsen TH, Hampe J, Wiencke K, Schrumpf E, Thorsby E, Lie BA, Broomé U, Schreiber S, Boberg KM (2006)
Genetic polymorphisms associated with inflammatory bowel disease do not confer risk for primary sclerosing cholangitis
Am J Gastroenterol, 102 (1), 115-21
PubMed 17100974

Karlsen TH, Lie BA, Frey Frøslie K, Thorsby E, Broomé U, Schrumpf E, Boberg KM (2006)
Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis
Gastroenterology, 131 (3), 781-7
PubMed 16952547

Melum E, Karlsen TH, Broomé U, Thorsby E, Schrumpf E, Boberg KM, Lie BA (2006)
The 32-base pair deletion of the chemokine receptor 5 gene (CCR5-Delta32) is not associated with primary sclerosing cholangitis in 363 Scandinavian patients
Tissue Antigens, 68 (1), 78-81
PubMed 16774544

Wiencke K, Boberg KM, Donaldson P, Harbo H, Ling V, Schrumpf E, Spurkland A (2006)
No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis
Scand J Gastroenterol, 41 (5), 586-91
PubMed 16638702

Publications 2005

Olsson R, Boberg KM, de Muckadell OS, Lindgren S, Hultcrantz R, Folvik G, Bell H, Gangsøy-Kristiansen M, Matre J, Rydning A, Wikman O, Danielsson A, Sandberg-Gertzén H, Ung KA, Eriksson A, Lööf L, Prytz H, Marschall HU, Broomé U (2005)
High-dose ursodeoxycholic acid in primary sclerosing cholangitis: a 5-year multicenter, randomized, controlled study
Gastroenterology, 129 (5), 1464-72
PubMed 16285948

Viken MK, Amundsen SS, Kvien TK, Boberg KM, Gilboe IM, Lilleby V, Sollid LM, Førre OT, Thorsby E, Smerdel A, Lie BA (2005)
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
Genes Immun, 6 (3), 271-3
PubMed 15759012

Publications 2004

Boberg KM, Schrumpf E (2004)
Diagnosis and treatment of cholangiocarcinoma
Curr Gastroenterol Rep, 6 (1), 52-9
PubMed 14720454

Wiencke K, Louka AS, Spurkland A, Vatn M, Schrumpf E, Boberg KM, IBSEN Study Group (2004)
Association of matrix metalloproteinase-1 and -3 promoter polymorphisms with clinical subsets of Norwegian primary sclerosing cholangitis patients
J Hepatol, 41 (2), 209-14
PubMed 15288468

Publications 2003

Boberg KM, Egeland T, Schrumpf E (2003)
Long-term effect of corticosteroid treatment in primary sclerosing cholangitis patients
Scand J Gastroenterol, 38 (9), 991-5
PubMed 14531538

Boberg KM, Jebsen P, Clausen OP, Aabakken L, Brekke I, Schrumpf E (2003)
Cholangiocarcinoma in situ in primary sclerosing cholangitis: diagnosis by brush cytology and treatment by liver transplantation
J Hepatol, 39 (3), 453
PubMed 12927935

Drivenes A, Bjøro K, Holter E, Bentdal Ø, Boberg KM (2003)
[Fulminant liver failure in acute hepatitis B virus infection]
Tidsskr Nor Laegeforen, 123 (2), 172-4
PubMed 12607499

Schrumpf E, Boberg KM (2003)
Hepatic and extrahepatic malignancies and primary sclerosing cholangitis
Gut, 52 (2), 165
PubMed 12524391

Publications 2002

Björnsson E, Boberg KM, Cullen S, Fleming K, Clausen OP, Fausa O, Schrumpf E, Chapman RW (2002)
Patients with small duct primary sclerosing cholangitis have a favourable long term prognosis
Gut, 51 (5), 731-5
PubMed 12377815

Boberg KM (2002)
Prevalence and epidemiology of autoimmune hepatitis
Clin Liver Dis, 6 (3), 635-47
PubMed 12362572

Boberg KM, Bergquist A, Mitchell S, Pares A, Rosina F, Broomé U, Chapman R, Fausa O, Egeland T, Rocca G, Schrumpf E (2002)
Cholangiocarcinoma in primary sclerosing cholangitis: risk factors and clinical presentation
Scand J Gastroenterol, 37 (10), 1205-11
PubMed 12408527

Boberg KM, Rocca G, Egeland T, Bergquist A, Broomé U, Caballeria L, Chapman R, Hultcrantz R, Mitchell S, Pares A, Rosina F, Schrumpf E (2002)
Time-dependent Cox regression model is superior in prediction of prognosis in primary sclerosing cholangitis
Hepatology, 35 (3), 652-7
PubMed 11870380

Schrumpf E, Boberg KM (2002)
Endoscopic treatment for primary sclerosing cholangitis?
J Hepatol, 36 (2), 278-9
PubMed 11830341

Publications 2001

Boberg KM, Spurkland A, Rocca G, Egeland T, Saarinen S, Mitchell S, Broomé U, Chapman R, Olerup O, Pares A, Rosina F, Schrumpf E (2001)
The HLA-DR3,DQ2 heterozygous genotype is associated with an accelerated progression of primary sclerosing cholangitis
Scand J Gastroenterol, 36 (8), 886-90
PubMed 11495087

Fleming KA, Boberg KM, Glaumann H, Bergquist A, Smith D, Clausen OP (2001)
Biliary dysplasia as a marker of cholangiocarcinoma in primary sclerosing cholangitis
J Hepatol, 34 (3), 360-5
PubMed 11322195

Mitchell SA, Grove J, Spurkland A, Boberg KM, Fleming KA, Day CP, Schrumpf E, Chapman RW, European Study Group of Primary Sclerosing Cholangitis (2001)
Association of the tumour necrosis factor alpha -308 but not the interleukin 10 -627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis
Gut, 49 (2), 288-94
PubMed 11454808

Schrumpf E, Boberg KM (2001)
Epidemiology of primary sclerosing cholangitis
Best Pract Res Clin Gastroenterol, 15 (4), 553-62
PubMed 11492967

Wiencke K, Spurkland A, Schrumpf E, Boberg KM (2001)
Primary sclerosing cholangitis is associated to an extended B8-DR3 haplotype including particular MICA and MICB alleles
Hepatology, 34 (4 Pt 1), 625-30
PubMed 11584356

Publications 2000

Boberg KM, Schrumpf E, Bergquist A, Broomé U, Pares A, Remotti H, Schjölberg A, Spurkland A, Clausen OP (2000)
Cholangiocarcinoma in primary sclerosing cholangitis: K-ras mutations and Tp53 dysfunction are implicated in the neoplastic development
J Hepatol, 32 (3), 374-80
PubMed 10735605

Schrumpf E, Boberg KM (2000)
Primary sclerosing cholangitis: challenges of a new millenium
Dig Liver Dis, 32 (9), 753-5
PubMed 11215553

Publications 1999

Boberg KM, Brosstad F, Egeland T, Egge T, Schrumpf E (1999)
Is a prolonged bleeding time associated with an increased risk of hemorrhage after liver biopsy?
Thromb Haemost, 81 (3), 378-81
PubMed 10102464

Giercksky T, Boberg KM, Farstad IN, Halvorsen S, Schrumpf E (1999)
Severe liver failure in exertional heat stroke
Scand J Gastroenterol, 34 (8), 824-7
PubMed 10499485

Spurkland A, Saarinen S, Boberg KM, Mitchell S, Broome U, Caballeria L, Ciusani E, Chapman R, Ercilla G, Fausa O, Knutsen I, Pares A, Rosina F, Olerup O, Thorsby E, Schrumpf E (1999)
HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations
Tissue Antigens, 53 (5), 459-69
PubMed 10372541

Publications 1998

Boberg KM, Aadland E, Jahnsen J, Raknerud N, Stiris M, Bell H (1998)
Incidence and prevalence of primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis in a Norwegian population
Scand J Gastroenterol, 33 (1), 99-103
PubMed 9489916

Publications 1997

Boberg KM, Schrumpf E (1997)
[Treatment of cholestatic liver diseases with ursodeoxycholic acid]
Tidsskr Nor Laegeforen, 117 (23), 3370-3
PubMed 9411890

Publications 1996

Boberg KM, Fausa O, Haaland T, Holter E, Mellbye OJ, Spurkland A, Schrumpf E (1996)
Features of autoimmune hepatitis in primary sclerosing cholangitis: an evaluation of 114 primary sclerosing cholangitis patients according to a scoring system for the diagnosis of autoimmune hepatitis
Hepatology, 23 (6), 1369-76
PubMed 8675153

Publications 1995

Boberg KM, Brinch L, Vatn M (1995)
Crohn disease and the myelodysplastic syndrome
Ann Intern Med, 122 (5), 395
PubMed 7847659

Publications 1994

Boberg KM, Lundin KE, Schrumpf E (1994)
Etiology and pathogenesis in primary sclerosing cholangitis
Scand J Gastroenterol Suppl, 204, 47-58
PubMed 7824878

Boberg KM, Schrumpf E, Fausa O, Elgjo K, Kolmannskog F, Haaland T, Holter E (1994)
Hepatobiliary disease in ulcerative colitis. An analysis of 18 patients with hepatobiliary lesions classified as small-duct primary sclerosing cholangitis
Scand J Gastroenterol, 29 (8), 744-52
PubMed 7973436

Boberg KM, Schrumpf E, Rogstad B, Berg KJ, Ganes T, Bergan A (1994)
[Treatment of paracetamol poisoning. An indication for liver transplantation?]
Tidsskr Nor Laegeforen, 114 (10), 1199-203
PubMed 8209319

Publications 1991

Boberg KM (1991)
[The significance of oxidized lipoproteins for the development of atherosclerosis. Antioxidants as a therapeutic alternative in atherosclerosis]
Tidsskr Nor Laegeforen, 111 (15), 1861-5
PubMed 1853321

Boberg KM, Pettersen KS, Prydz H (1991)
Toxicity of sitosterol to human umbilical vein endothelial cells in vitro
Scand J Clin Lab Invest, 51 (6), 509-16
PubMed 1767244

Lund E, Boberg KM, Byström S, Olund J, Carlström K, Björkhem I (1991)
Formation of novel C21-bile acids from cholesterol in the rat. Structure identification of the major Di- and trihydroxylated species
J Biol Chem, 266 (8), 4929-37
PubMed 2002039

Pettersen KS, Boberg KM, Stabursvik A, Prydz H (1991)
Toxicity of oxygenated cholesterol derivatives toward cultured human umbilical vein endothelial cells
Arterioscler Thromb, 11 (2), 423-8
PubMed 1900193

Publications 1990

Boberg KM, Einarsson K, Björkhem I (1990)
Apparent lack of conversion of sitosterol into C24-bile acids in humans
J Lipid Res, 31 (6), 1083-8
PubMed 2373958

Boberg KM, Lund E, Olund J, Björkhem I (1990)
Formation of C21 bile acids from plant sterols in the rat
J Biol Chem, 265 (14), 7967-75
PubMed 2335512

Publications 1989

Boberg KM, Akerlund JE, Björkhem I (1989)
Effect of sitosterol on the rate-limiting enzymes in cholesterol synthesis and degradation
Lipids, 24 (1), 9-12
PubMed 2747437

Boberg KM, Smith-Kielland I, Stabursvik A, Stokke O (1989)
Difference in cytotoxicity of (22R)-cholest-5-ene-3 beta,7 alpha,22-triol and (22R)-cholest-5-ene-3 beta,7 beta,22-triol is not explained by different patterns of metabolites
J Steroid Biochem, 33 (6), 1087-9
PubMed 2615353

Boberg KM, Stabursvik A, Björkhem I, Stokke O (1989)
Dehydroxylation of a 7 beta-hydroxy-C27 plant sterol in rat liver
Biochim Biophys Acta, 1004 (3), 321-6
PubMed 2758026

Publications 1988

Boberg KM, Skrede S (1988)
Content of sitosterol, cholestanol, and cholesterol in very low density lipoproteins of rat liver perfusate
Scand J Gastroenterol, 23 (4), 442-8
PubMed 3381065

Publications 1987

Boberg KM, Björkhem I, Skrede S (1987)
Normal activity of C27-steroid 26-hydroxylase in cultured sitosterolaemia fibroblasts
Scand J Clin Lab Invest, 47 (7), 701-4
PubMed 3685870

Publications 1986

Boberg KM, Skrede B, Skrede S (1986)
Metabolism of 24-ethyl-4-cholesten-3-one and 24-ethyl-5-cholesten-3 beta-ol (sitosterol) after intraperitoneal injection in the rat
Scand J Clin Lab Invest Suppl, 184, 47-54
PubMed 3473613