Jan Brinchmann's group

Cell Therapy Research Group


Tissue engineering is a relatively new niche within the field of human therapeutics. It involves the use of cells, frequently combined with biomaterials, to regenerate diseased, damaged or surgically removed tissues. Stem cells are immature cells with great potential for self-replication, but also for differentiation to become tissue-specific cells. Work performed in our group is directed towards the use stem and progenitor cells for tissue engineering of cartilage, bone and cardiovascular tissues. In the process we aim to unravel molecular mechanisms for cell differentiation and de-differentiation, and to understand the interactions between cells, extracellular matrix and biomaterials.


  • Tissue engineering of hyaline cartilage
  • Molecular mechanisms for chondrogenic differentiation of mesenchymal stem cells
  • Molecular mechanisms for bone generation
  • Tissue engineering of cardiovascular tissues
  • Molecular mechanisms for neovascularization

Link to Cell Therapy Research Group home page at UiO


Contact information:

Jan E. Brinchmann, MD, PhD. - Department of immunology - Oslo University Hospital Rikshospitalet PO Box 4950 Nydalen NO-0424 Oslo, Norway

About research focus